Page last updated: 2024-10-20

phthalic acid and Infertility

phthalic acid has been researched along with Infertility in 17 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Infertility: A reduced or absent capacity to reproduce.

Research Excerpts

ExcerptRelevanceReference
"Exposure to phenols and phthalates has been separately linked to increased risks of infertility in women of reproductive age."8.12Association between co-exposure to phenols and phthalates mixture and infertility risk in women. ( Chen, Q; Yang, H; Zhan, W; Zhang, J, 2022)
" Four areas for development are suggested, and selected examples of research involved in those areas are discussed: (1) Translational applications: workplace exposures thought to cause infertility in men (1,2-dibromo-3-chloropropane, DBCP) and menstrual disturbances in women (2-bromopropane, 2BP) are given as examples of human effects that have prompted animal studies."4.81Reproductive toxicology: current and future directions. ( Hoyer, PB, 2001)
"Exposure to phenols and phthalates has been separately linked to increased risks of infertility in women of reproductive age."4.12Association between co-exposure to phenols and phthalates mixture and infertility risk in women. ( Chen, Q; Yang, H; Zhan, W; Zhang, J, 2022)
"Male infertility is a serious concern for public health, and the possible role of exposure to plasticizers such as phthalates and bisphenol A in contributing to the condition is widely debated."1.72A Case-Control Study on the Effects of Plasticizers Exposure on Male Fertility. ( Alteri, A; Capanna, S; Caporossi, L; Paci, E; Papaleo, B; Pigini, D; Tranfo, G; Viganò, P, 2022)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's7 (41.18)24.3611
2020's9 (52.94)2.80

Authors

AuthorsStudies
Yland, JJ1
Zhang, Y1
Williams, PL2
Mustieles, V2
Vagios, S1
Souter, I3
Calafat, AM2
Hauser, R3
Messerlian, C2
Zhan, W1
Yang, H1
Zhang, J1
Chen, Q1
Cosci, I1
Garolla, A1
Cabrelle, A1
Sut, S1
Dall'Acqua, S1
Ferlin, A1
Foresta, C1
De Toni, L1
Abdo, N1
Al-Khalaileh, H1
Alajlouni, M1
Hamadneh, J1
Alajlouni, AM1
Caporossi, L2
Viganò, P1
Paci, E2
Capanna, S2
Alteri, A1
Pigini, D1
Tranfo, G2
Papaleo, B2
Oluwayiose, OA1
Houle, E1
Whitcomb, BW2
Suvorov, A2
Rahil, T3
Sites, CK2
Krawetz, SA2
Visconti, PE1
Pilsner, JR3
Begum, TF1
Gerona, R1
Melamed, J1
McGough, A1
Lenhart, N1
Wong, R1
Mok-Lin, E1
Butts, CD1
Feingold, BJ1
Romeiko, XX1
Fujimoto, VY1
Bloom, MS1
Feng, YL1
Liao, X1
Chen, D1
Takser, L1
Cakmak, S1
Chan, P1
Zhu, J1
Trnka, B1
Polan, M1
Zigmont, VA1
Wu, H2
Estill, MS1
Shershebnev, A1
Dinnie, H1
Mínguez-Alarcón, L1
Christou, G1
Ford, JB1
Dimitriadis, I1
Kucińska, M1
Murias, M1
Dodge, LE1
Williams, MA1
Missmer, SA1
Olmsted, A1
Cantonwine, DE1
Shahsavari, S1
Sites, C1
Pak, VM1
McCauley, LA1
Pinto-Martin, J1
Aragona, C1
Romanzi, D1
De Carolis, C1
De Rosa, M1
Pera, A1
Hoyer, PB1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.[NCT00011713]1,474 participants (Actual)Observational1999-10-31Completed
To Investigate the Effect of Plasticizers on the Pregnancy in Vitro Fertilization Cycles[NCT03733912]80 participants (Actual)Observational2018-07-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for phthalic acid and Infertility

ArticleYear
[Cosmetics as source of xenoestrogens exposure].
    Przeglad lekarski, 2013, Volume: 70, Issue:8

    Topics: Aluminum; Cosmetics; Environmental Exposure; Estrogens; Humans; Infertility; Neoplasms; Parabens; Ph

2013
Phthalate exposures and human health concerns: A review and implications for practice.
    AAOHN journal : official journal of the American Association of Occupational Health Nurses, 2011, Volume: 59, Issue:5

    Topics: Animals; Chemical Industry; Education, Nursing, Continuing; Female; Humans; Infertility; Male; Occup

2011
Reproductive toxicology: current and future directions.
    Biochemical pharmacology, 2001, Dec-15, Volume: 62, Issue:12

    Topics: Animals; Endocrine System; Environmental Exposure; Estrogens, Non-Steroidal; Female; Humans; Hydroca

2001

Other Studies

14 other studies available for phthalic acid and Infertility

ArticleYear
Phthalate and DINCH urinary concentrations across pregnancy and risk of preterm birth.
    Environmental pollution (Barking, Essex : 1987), 2022, Jan-01, Volume: 292, Issue:Pt B

    Topics: Female; Humans; Infant, Newborn; Infertility; Phthalic Acids; Pregnancy; Premature Birth; Prospectiv

2022
Association between co-exposure to phenols and phthalates mixture and infertility risk in women.
    Environmental research, 2022, Volume: 215, Issue:Pt 1

    Topics: Adolescent; Adult; Bayes Theorem; Benzhydryl Compounds; Diethylhexyl Phthalate; Environmental Exposu

2022
Lipophilic phthalic acid esters impair human sperm acrosomal reaction through the likely inhibition of phospholipase A
    Biochemical pharmacology, 2022, Volume: 205

    Topics: Arachidonic Acid; Calcimycin; Calcium Ionophores; Dibutyl Phthalate; Endocrine Disruptors; Esters; H

2022
Screening for phthalates biomarkers and its potential role in infertility outcomes in Jordan.
    Journal of exposure science & environmental epidemiology, 2023, Volume: 33, Issue:2

    Topics: Biomarkers; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans

2023
A Case-Control Study on the Effects of Plasticizers Exposure on Male Fertility.
    International journal of environmental research and public health, 2022, 12-23, Volume: 20, Issue:1

    Topics: Case-Control Studies; Environmental Exposure; Environmental Pollutants; Fertility; Humans; Infant, N

2022
Urinary phthalate metabolites and small non-coding RNAs from seminal plasma extracellular vesicles among men undergoing infertility treatment.
    Environmental pollution (Barking, Essex : 1987), 2023, Jul-15, Volume: 329

    Topics: Environmental Exposure; Environmental Pollutants; Extracellular Vesicles; Female; Humans; Infertilit

2023
Sources of exposure to urinary phthalates among couples undergoing infertility treatment.
    International journal of hygiene and environmental health, 2020, Volume: 229

    Topics: Adult; Anti-Allergic Agents; Cosmetics; Dietary Supplements; Environmental Exposure; Environmental P

2020
Correlations of phthalate metabolites in urine samples from fertile and infertile men: Free-form concentration vs. conjugated-form concentration.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 263, Issue:Pt A

    Topics: Biomarkers; Environmental Exposure; Environmental Pollutants; Fertility; Humans; Infertility; Male;

2020
Exposure to Di-2-ethylhexyl phthalate (DEHP) and infertility in women, NHANES 2013-2016.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 103

    Topics: Adult; Cross-Sectional Studies; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Exposure

2021
Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional study.
    Human reproduction (Oxford, England), 2017, 11-01, Volume: 32, Issue:11

    Topics: Adult; Cross-Sectional Studies; DNA Methylation; Female; Fertilization in Vitro; Humans; Infertility

2017
Placental weight in relation to maternal and paternal preconception and prenatal urinary phthalate metabolite concentrations among subfertile couples.
    Environmental research, 2019, Volume: 169

    Topics: Boston; Child; Environmental Pollutants; Family Characteristics; Fathers; Female; Humans; Infant, Ne

2019
Associations between paternal urinary phthalate metabolite concentrations and reproductive outcomes among couples seeking fertility treatment.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 58

    Topics: Adolescent; Adult; Biomarkers; Embryo Implantation; Fathers; Female; Fertility; Fertilization in Vit

2015
Urinary phthalate and phthalate alternative metabolites and isoprostane among couples undergoing fertility treatment.
    Environmental research, 2017, Volume: 153

    Topics: Adolescent; Adult; Cross-Sectional Studies; Diethylhexyl Phthalate; Environmental Exposure; Female;

2017
Urinary phthalate monoesters concentration in couples with infertility problems.
    Toxicology letters, 2012, Aug-13, Volume: 213, Issue:1

    Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Infertility; Infe

2012