phthalic acid has been researched along with Infertility, Male in 17 studies
phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
Infertility, Male: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lycopene (LYC) is a possible preventive and therapeutic agent for male infertility owing to its antioxidant properties." | 1.91 | Connexin-43 is a promising target for lycopene preventing phthalate-induced spermatogenic disorders. ( Chen, MS; Cui, JG; Li, JL; Li, XN; Wang, JX; Zhang, H; Zhao, Y, 2023) |
| " VA and VC supplementation attenuated the toxic effects of DEHP on the testicular functions, morphology, and semen characterization of the experimental adult male Wistar rats." | 1.72 | Vanillic acid and vitamin C attenuated di-2-ethylhexyl phthalate-induced testicular toxicity in adult male rats. ( Adedotun, OA; Adejayi, J; Gbotolorun, SC; Iteire, K; Ogunlade, B, 2022) |
| "Lycopene (LYC) is a natural antioxidant agent that has been recognized as a possible therapeutic option for treating male infertility." | 1.72 | Phthalate-induced testosterone/androgen receptor pathway disorder on spermatogenesis and antagonism of lycopene. ( Chen, MS; Cui, JG; Li, JL; Li, XN; Wang, JX; Zhang, H; Zhao, Y, 2022) |
| " After adjustment for age, body mass index (BMI), abstinence, smoking, drinking, and education, there was a borderline-significant dose-response relationship between MBP and sperm concentration, with odd ratios (ORs) 1." | 1.38 | Phthalates exposure of Chinese reproductive age couples and its effect on male semen quality, a primary study. ( Bao, H; Liu, F; Liu, L; Shen, H; Zhang, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Ogunlade, B | 1 |
| Gbotolorun, SC | 1 |
| Adedotun, OA | 1 |
| Iteire, K | 1 |
| Adejayi, J | 1 |
| Zhao, Y | 2 |
| Chen, MS | 2 |
| Wang, JX | 2 |
| Cui, JG | 2 |
| Zhang, H | 2 |
| Li, XN | 2 |
| Li, JL | 2 |
| Rana, R | 1 |
| Joon, S | 1 |
| Kumar Jain, A | 1 |
| Kumar Mohanty, N | 1 |
| Liu, L | 2 |
| Wang, H | 1 |
| Tian, M | 1 |
| Zhang, J | 2 |
| Panuwet, P | 1 |
| D'Souza, PE | 1 |
| Barr, DB | 1 |
| Huang, Q | 1 |
| Xia, Y | 1 |
| Shen, H | 2 |
| Han, X | 1 |
| Cui, Z | 1 |
| Zhou, N | 1 |
| Ma, M | 1 |
| Li, L | 1 |
| Li, Y | 1 |
| Lin, H | 1 |
| Ao, L | 1 |
| Shu, W | 1 |
| Liu, J | 1 |
| Cao, J | 1 |
| Kranvogl, R | 1 |
| Knez, J | 1 |
| Miuc, A | 1 |
| Vončina, E | 1 |
| Vončina, DB | 1 |
| Vlaisavljević, V | 1 |
| Kumar, N | 1 |
| Srivastava, S | 1 |
| Roy, P | 1 |
| Den Hond, E | 1 |
| Tournaye, H | 1 |
| De Sutter, P | 1 |
| Ombelet, W | 1 |
| Baeyens, W | 1 |
| Covaci, A | 1 |
| Cox, B | 1 |
| Nawrot, TS | 1 |
| Van Larebeke, N | 1 |
| D'Hooghe, T | 1 |
| Chang, WH | 1 |
| Li, SS | 1 |
| Wu, MH | 1 |
| Pan, HA | 1 |
| Lee, CC | 1 |
| Jurewicz, J | 1 |
| Hanke, W | 1 |
| Radwan, M | 1 |
| Bonde, JP | 1 |
| Bao, H | 1 |
| Liu, F | 1 |
| Tranfo, G | 1 |
| Caporossi, L | 1 |
| Paci, E | 1 |
| Aragona, C | 1 |
| Romanzi, D | 1 |
| De Carolis, C | 1 |
| De Rosa, M | 1 |
| Capanna, S | 1 |
| Papaleo, B | 1 |
| Pera, A | 1 |
| Rozati, R | 1 |
| Reddy, PP | 1 |
| Reddanna, P | 1 |
| Mujtaba, R | 1 |
| Hauser, R | 1 |
| Cravedi, JP | 1 |
| Zalko, D | 1 |
| Savouret, JF | 1 |
| Menuet, A | 1 |
| Jégou, B | 1 |
| Chen, GR | 1 |
| Dong, L | 1 |
| Ge, RS | 1 |
| Hardy, MP | 1 |
4 reviews available for phthalic acid and Infertility, Male
| Article | Year |
|---|---|
Human exposure to endocrine disrupting chemicals and fertility: A case-control study in male subfertility patients.
Topics: Adult; Benzhydryl Compounds; Case-Control Studies; Dioxins; Endocrine Disruptors; Environmental Expo | 2015 |
Environmental factors and semen quality.
Topics: Cell Phone; Environmental Exposure; Environmental Pollutants; Humans; Infertility, Male; Male; Pesti | 2009 |
The environment and male fertility: recent research on emerging chemicals and semen quality.
Topics: Age Factors; Environmental Monitoring; Environmental Pollutants; Epidemiological Monitoring; Fertili | 2006 |
[The concept of endocrine disruption and human health].
Topics: Abnormalities, Drug-Induced; Animals; Benzhydryl Compounds; Diethylstilbestrol; Endocrine Disruptors | 2007 |
1 trial available for phthalic acid and Infertility, Male
| Article | Year |
|---|---|
Role of environmental estrogens in the deterioration of male factor fertility.
Topics: Adult; Animals; Diet; Diet, Vegetarian; Environmental Pollutants; Esters; Fishes; Humans; Infertilit | 2002 |
12 other studies available for phthalic acid and Infertility, Male
| Article | Year |
|---|---|
Vanillic acid and vitamin C attenuated di-2-ethylhexyl phthalate-induced testicular toxicity in adult male rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Diethylhexyl Phthalate; Female; Humans; Infertility, Male; Mal | 2022 |
Connexin-43 is a promising target for lycopene preventing phthalate-induced spermatogenic disorders.
Topics: Animals; Connexin 43; Diethylhexyl Phthalate; Humans; Infertility, Male; Lycopene; Male; Mice; Semen | 2023 |
Phthalate-induced testosterone/androgen receptor pathway disorder on spermatogenesis and antagonism of lycopene.
Topics: Androgens; Diethylhexyl Phthalate; Humans; Infertility, Male; Lycopene; Male; Phthalic Acids; Recept | 2022 |
A study on the effect of phthalate esters and their metabolites on idiopathic infertile males.
Topics: Environmental Exposure; Esters; Humans; Infertility, Male; Male; Phthalic Acids; Semen Analysis; Spe | 2020 |
Phthalate metabolites related to infertile biomarkers and infertility in Chinese men.
Topics: Adult; Asian People; Biomarkers; Case-Control Studies; Diethylhexyl Phthalate; Environmental Exposur | 2017 |
Urinary phthalate metabolites and male reproductive function parameters in Chongqing general population, China.
Topics: Adult; China; DNA Damage; Environmental Exposure; Gonadal Steroid Hormones; Humans; Infertility, Mal | 2014 |
Simultaneous determination of phthalates, their metabolites, alkylphenols and bisphenol A using GC-MS in urine of men with fertility problems.
Topics: Adult; Benzhydryl Compounds; Calibration; Endocrine Disruptors; Gas Chromatography-Mass Spectrometry | 2014 |
Impact of low molecular weight phthalates in inducing reproductive malfunctions in male mice: Special emphasis on Sertoli cell functions.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Immunoenzyme Techniques; Infertility, Ma | 2015 |
Phthalates might interfere with testicular function by reducing testosterone and insulin-like factor 3 levels.
Topics: Adult; Case-Control Studies; Humans; Infertility, Male; Insulin; Male; Middle Aged; Phthalic Acids; | 2015 |
Phthalates exposure of Chinese reproductive age couples and its effect on male semen quality, a primary study.
Topics: Adult; China; Cohort Studies; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutan | 2012 |
Urinary phthalate monoesters concentration in couples with infertility problems.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Infertility; Infe | 2012 |
[Relationship between phthalates and testicular dysgenesis syndrome].
Topics: Adult; Cryptorchidism; Female; Fetus; Gonadal Dysgenesis; Humans; Infant, Newborn; Infertility, Male | 2007 |