phthalic acid has been researched along with Diabetes Mellitus, Type 2 in 19 studies
phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Excerpt | Relevance | Reference |
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" The goal of this study was to compare the urine levels of bisphenol A and phthalate metabolites in subgroups of patients with metabolic syndrome composed of patients with and without three important components of metabolic syndrome (hypertension, dyslipidemia and diabetes)." | 7.83 | Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study. ( Haluzík, M; Lacinová, Z; Malý, M; Matějková, D; Matoulek, M; Mráz, M; Müllerová, D; Pavloušková, J; Piecha, R; Svačina, Š; Vavrouš, A; Vrbík, K, 2016) |
" The goal of this study was to compare the urine levels of bisphenol A and phthalate metabolites in subgroups of patients with metabolic syndrome composed of patients with and without three important components of metabolic syndrome (hypertension, dyslipidemia and diabetes)." | 3.83 | Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study. ( Haluzík, M; Lacinová, Z; Malý, M; Matějková, D; Matoulek, M; Mráz, M; Müllerová, D; Pavloušková, J; Piecha, R; Svačina, Š; Vavrouš, A; Vrbík, K, 2016) |
"We investigated the incidence of type 2 diabetes mellitus (T2DM) in Saudi subjects and correlated it with urinary phthalate metabolites' screening study." | 1.72 | Screening the incidence of diabetogensis with urinary phthalate in Saudi subjects. ( Al-Bazi, MM; Al-Malki, AL; Kumosani, TA; Moselhy, SS, 2022) |
" Phthalate was administered in drinking water at a daily dosage of 100 mg/kg." | 1.42 | Influence of phthalates on glucose homeostasis and atherosclerosis in hyperlipidemic mice. ( Chen, MH; Shi, W; Zhou, W, 2015) |
" Mexican-Americans and non-Hispanic blacks had stronger dose-response relationships for MnBP, MiBP, MCPP and ∑DEHP compared to non-Hispanic whites." | 1.40 | Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008. ( Huang, T; Isganaitis, E; James-Todd, T; Saxena, AR, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 11 (57.89) | 24.3611 |
2020's | 8 (42.11) | 2.80 |
Authors | Studies |
---|---|
Eales, J | 1 |
Bethel, A | 1 |
Galloway, T | 1 |
Hopkinson, P | 1 |
Morrissey, K | 1 |
Short, RE | 1 |
Garside, R | 1 |
Chen, Y | 2 |
Zhang, W | 2 |
Chen, J | 2 |
Wang, N | 2 |
Chen, C | 2 |
Wang, Y | 2 |
Wan, H | 2 |
Chen, B | 2 |
Lu, Y | 2 |
Al-Bazi, MM | 1 |
Kumosani, TA | 1 |
Al-Malki, AL | 1 |
Moselhy, SS | 1 |
Liu, XK | 1 |
Si, SW | 1 |
Ye, Y | 1 |
Li, JY | 1 |
Lyu, HH | 1 |
Ma, YM | 1 |
Zou, CY | 1 |
Sun, HJ | 1 |
Xue, L | 1 |
Xu, W | 1 |
Geng, HF | 1 |
Liang, J | 1 |
Sargis, RM | 1 |
Simmons, RA | 1 |
Chang, JW | 1 |
Liao, KW | 1 |
Huang, CY | 1 |
Huang, HB | 1 |
Chang, WT | 1 |
Jaakkola, JJK | 1 |
Hsu, CC | 1 |
Chen, PC | 1 |
Huang, PC | 1 |
Wang, G | 1 |
Chen, Q | 1 |
Tian, P | 1 |
Wang, L | 2 |
Li, X | 1 |
Lee, YK | 1 |
Zhao, J | 1 |
Zhang, H | 2 |
Chen, W | 1 |
Duan, Y | 3 |
Sun, H | 3 |
Yao, Y | 1 |
Han, L | 3 |
Chen, L | 3 |
Wang, B | 1 |
Zhu, L | 1 |
Luo, Y | 1 |
Mengozzi, A | 1 |
Carli, F | 1 |
Biancalana, E | 1 |
Della Latta, V | 1 |
Seghieri, M | 1 |
Gastaldelli, A | 1 |
Solini, A | 1 |
Kim, H | 1 |
Nam, K | 1 |
Oh, S | 1 |
Son, S | 1 |
Jeon, D | 1 |
Gye, MC | 1 |
Shin, I | 1 |
Huang, T | 1 |
Saxena, AR | 1 |
Isganaitis, E | 1 |
James-Todd, T | 1 |
Sun, Q | 2 |
Cornelis, MC | 1 |
Townsend, MK | 1 |
Tobias, DK | 1 |
Eliassen, AH | 1 |
Franke, AA | 1 |
Hauser, R | 1 |
Hu, FB | 1 |
Zhou, W | 1 |
Chen, MH | 1 |
Shi, W | 1 |
Song, Y | 2 |
Chou, EL | 1 |
Baecker, A | 1 |
You, NC | 1 |
Liu, S | 1 |
Okada, AK | 1 |
Teranishi, K | 1 |
Isas, JM | 1 |
Bedrood, S | 1 |
Chow, RH | 1 |
Langen, R | 1 |
Piecha, R | 1 |
Svačina, Š | 1 |
Malý, M | 1 |
Vrbík, K | 1 |
Lacinová, Z | 1 |
Haluzík, M | 1 |
Pavloušková, J | 1 |
Vavrouš, A | 1 |
Matějková, D | 1 |
Müllerová, D | 1 |
Mráz, M | 1 |
Matoulek, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - SGLT2 Subprotocol[NCT04242758] | Phase 4 | 30 participants (Actual) | Interventional | 2019-06-04 | Active, not recruiting | ||
Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - Protocol 2[NCT03622957] | 200 participants (Anticipated) | Observational | 2018-08-10 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for phthalic acid and Diabetes Mellitus, Type 2
Article | Year |
---|---|
Human health impacts of exposure to phthalate plasticizers: An overview of reviews.
Topics: Diabetes Mellitus, Type 2; Environmental Exposure; Female; Humans; Male; Phthalic Acids; Plasticizer | 2022 |
Environmental neglect: endocrine disruptors as underappreciated but potentially modifiable diabetes risk factors.
Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Endocrine Disruptors; Environmental Pollutants; Hum | 2019 |
Endocrine-disrupting chemicals, risk of type 2 diabetes, and diabetes-related metabolic traits: A systematic review and meta-analysis.
Topics: Benzhydryl Compounds; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dioxins; Endocrine Disrupt | 2016 |
16 other studies available for phthalic acid and Diabetes Mellitus, Type 2
Article | Year |
---|---|
Association of Phthalate Exposure with Thyroid Function and Thyroid Homeostasis Parameters in Type 2 Diabetes.
Topics: Aged; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Hom | 2021 |
Screening the incidence of diabetogensis with urinary phthalate in Saudi subjects.
Topics: C-Peptide; Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Pollutants; Humans; Inci | 2022 |
The Link between Exposure to Phthalates and Type 2 Diabetes Mellitus: A Study Based on NHANES Data and Bioinformatic Analysis.
Topics: Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Monitoring; Environmental Pollutant | 2023 |
Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.
Topics: Adult; Albuminuria; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diethylhexyl Pht | 2020 |
Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents.
Topics: Animals; Diabetes Mellitus, Type 2; Diethylhexyl Phthalate; Dysbiosis; Gastrointestinal Microbiome; | 2020 |
Perturbation of serum metabolome in relation to type 2 diabetes mellitus and urinary levels of phthalate metabolites and bisphenols.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Humans; Metabolome; Metabolomics; Phthalic Acids | 2021 |
Exposure to phthalates and cardiovascular diseases in Chinese with type 2 diabetes.
Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; China; Diabetes Mellitus, Type 2; Environme | 2021 |
Exposure to phthalates in patients with diabetes and its association with oxidative stress, adiponectin, and inflammatory cytokines.
Topics: Adiponectin; Adult; Aged; Biomarkers; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Hum | 2017 |
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp | 2019 |
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp | 2019 |
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp | 2019 |
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp | 2019 |
Association between phthalate exposure and glycosylated hemoglobin, fasting glucose, and type 2 diabetes mellitus: A case-control study in China.
Topics: Aged; Blood Glucose; China; Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Polluta | 2019 |
Toxicological assessment of phthalates and their alternatives using human keratinocytes.
Topics: Diabetes Mellitus, Type 2; Dibutyl Phthalate; Environmental Pollutants; Humans; Keratinocytes; Phtha | 2019 |
Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008.
Topics: Adolescent; Adult; Aged; Black People; Blood Glucose; Child; Diabetes Mellitus, Type 2; Endocrine Di | 2014 |
Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: a prospective investigation in the Nurses' Health Study (NHS) and NHSII cohorts.
Topics: Aged; Benzhydryl Compounds; Body Mass Index; Diabetes Mellitus, Type 2; Environmental Exposure; Envi | 2014 |
Influence of phthalates on glucose homeostasis and atherosclerosis in hyperlipidemic mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Endocrine Dis | 2015 |
Diabetic Risk Factors Promote Islet Amyloid Polypeptide Misfolding by a Common, Membrane-mediated Mechanism.
Topics: Circular Dichroism; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Membranes; Microsc | 2016 |
Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study.
Topics: Benzhydryl Compounds; Biomarkers; Chromatography, High Pressure Liquid; Czech Republic; Diabetes Mel | 2016 |