Page last updated: 2024-10-20

phthalic acid and Diabetes Mellitus, Adult-Onset

phthalic acid has been researched along with Diabetes Mellitus, Adult-Onset in 19 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Research Excerpts

ExcerptRelevanceReference
" The goal of this study was to compare the urine levels of bisphenol A and phthalate metabolites in subgroups of patients with metabolic syndrome composed of patients with and without three important components of metabolic syndrome (hypertension, dyslipidemia and diabetes)."7.83Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study. ( Haluzík, M; Lacinová, Z; Malý, M; Matějková, D; Matoulek, M; Mráz, M; Müllerová, D; Pavloušková, J; Piecha, R; Svačina, Š; Vavrouš, A; Vrbík, K, 2016)
" The goal of this study was to compare the urine levels of bisphenol A and phthalate metabolites in subgroups of patients with metabolic syndrome composed of patients with and without three important components of metabolic syndrome (hypertension, dyslipidemia and diabetes)."3.83Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study. ( Haluzík, M; Lacinová, Z; Malý, M; Matějková, D; Matoulek, M; Mráz, M; Müllerová, D; Pavloušková, J; Piecha, R; Svačina, Š; Vavrouš, A; Vrbík, K, 2016)
"We investigated the incidence of type 2 diabetes mellitus (T2DM) in Saudi subjects and correlated it with urinary phthalate metabolites' screening study."1.72Screening the incidence of diabetogensis with urinary phthalate in Saudi subjects. ( Al-Bazi, MM; Al-Malki, AL; Kumosani, TA; Moselhy, SS, 2022)
" Phthalate was administered in drinking water at a daily dosage of 100 mg/kg."1.42Influence of phthalates on glucose homeostasis and atherosclerosis in hyperlipidemic mice. ( Chen, MH; Shi, W; Zhou, W, 2015)
" Mexican-Americans and non-Hispanic blacks had stronger dose-response relationships for MnBP, MiBP, MCPP and ∑DEHP compared to non-Hispanic whites."1.40Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008. ( Huang, T; Isganaitis, E; James-Todd, T; Saxena, AR, 2014)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (57.89)24.3611
2020's8 (42.11)2.80

Authors

AuthorsStudies
Eales, J1
Bethel, A1
Galloway, T1
Hopkinson, P1
Morrissey, K1
Short, RE1
Garside, R1
Chen, Y2
Zhang, W2
Chen, J2
Wang, N2
Chen, C2
Wang, Y2
Wan, H2
Chen, B2
Lu, Y2
Al-Bazi, MM1
Kumosani, TA1
Al-Malki, AL1
Moselhy, SS1
Liu, XK1
Si, SW1
Ye, Y1
Li, JY1
Lyu, HH1
Ma, YM1
Zou, CY1
Sun, HJ1
Xue, L1
Xu, W1
Geng, HF1
Liang, J1
Sargis, RM1
Simmons, RA1
Chang, JW1
Liao, KW1
Huang, CY1
Huang, HB1
Chang, WT1
Jaakkola, JJK1
Hsu, CC1
Chen, PC1
Huang, PC1
Wang, G1
Chen, Q1
Tian, P1
Wang, L2
Li, X1
Lee, YK1
Zhao, J1
Zhang, H2
Chen, W1
Duan, Y3
Sun, H3
Yao, Y1
Han, L3
Chen, L3
Wang, B1
Zhu, L1
Luo, Y1
Mengozzi, A1
Carli, F1
Biancalana, E1
Della Latta, V1
Seghieri, M1
Gastaldelli, A1
Solini, A1
Kim, H1
Nam, K1
Oh, S1
Son, S1
Jeon, D1
Gye, MC1
Shin, I1
Huang, T1
Saxena, AR1
Isganaitis, E1
James-Todd, T1
Sun, Q2
Cornelis, MC1
Townsend, MK1
Tobias, DK1
Eliassen, AH1
Franke, AA1
Hauser, R1
Hu, FB1
Zhou, W1
Chen, MH1
Shi, W1
Song, Y2
Chou, EL1
Baecker, A1
You, NC1
Liu, S1
Okada, AK1
Teranishi, K1
Isas, JM1
Bedrood, S1
Chow, RH1
Langen, R1
Piecha, R1
Svačina, Š1
Malý, M1
Vrbík, K1
Lacinová, Z1
Haluzík, M1
Pavloušková, J1
Vavrouš, A1
Matějková, D1
Müllerová, D1
Mráz, M1
Matoulek, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - SGLT2 Subprotocol[NCT04242758]Phase 430 participants (Actual)Interventional2019-06-04Active, not recruiting
Exploring the Association Between Phthalates Exposure, Measured Through Their Urinary Metabolites, and Renal Function Impairment in Individuals With TYpe 2 Diabetes - Protocol 2[NCT03622957]200 participants (Anticipated)Observational2018-08-10Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for phthalic acid and Diabetes Mellitus, Adult-Onset

ArticleYear
Human health impacts of exposure to phthalate plasticizers: An overview of reviews.
    Environment international, 2022, Volume: 158

    Topics: Diabetes Mellitus, Type 2; Environmental Exposure; Female; Humans; Male; Phthalic Acids; Plasticizer

2022
Environmental neglect: endocrine disruptors as underappreciated but potentially modifiable diabetes risk factors.
    Diabetologia, 2019, Volume: 62, Issue:10

    Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Endocrine Disruptors; Environmental Pollutants; Hum

2019
Endocrine-disrupting chemicals, risk of type 2 diabetes, and diabetes-related metabolic traits: A systematic review and meta-analysis.
    Journal of diabetes, 2016, Volume: 8, Issue:4

    Topics: Benzhydryl Compounds; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dioxins; Endocrine Disrupt

2016

Other Studies

16 other studies available for phthalic acid and Diabetes Mellitus, Adult-Onset

ArticleYear
Association of Phthalate Exposure with Thyroid Function and Thyroid Homeostasis Parameters in Type 2 Diabetes.
    Journal of diabetes research, 2021, Volume: 2021

    Topics: Aged; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Hom

2021
Screening the incidence of diabetogensis with urinary phthalate in Saudi subjects.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:19

    Topics: C-Peptide; Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Pollutants; Humans; Inci

2022
The Link between Exposure to Phthalates and Type 2 Diabetes Mellitus: A Study Based on NHANES Data and Bioinformatic Analysis.
    Biomedical and environmental sciences : BES, 2023, 09-20, Volume: 36, Issue:9

    Topics: Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Monitoring; Environmental Pollutant

2023
Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.
    International journal of hygiene and environmental health, 2020, Volume: 224

    Topics: Adult; Albuminuria; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diethylhexyl Pht

2020
Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 261

    Topics: Animals; Diabetes Mellitus, Type 2; Diethylhexyl Phthalate; Dysbiosis; Gastrointestinal Microbiome;

2020
Perturbation of serum metabolome in relation to type 2 diabetes mellitus and urinary levels of phthalate metabolites and bisphenols.
    Environment international, 2021, Volume: 155

    Topics: Biomarkers; Diabetes Mellitus, Type 2; Humans; Metabolome; Metabolomics; Phthalic Acids

2021
Exposure to phthalates and cardiovascular diseases in Chinese with type 2 diabetes.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:41

    Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; China; Diabetes Mellitus, Type 2; Environme

2021
Exposure to phthalates in patients with diabetes and its association with oxidative stress, adiponectin, and inflammatory cytokines.
    Environment international, 2017, Volume: 109

    Topics: Adiponectin; Adult; Aged; Biomarkers; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Hum

2017
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
    The Journal of clinical endocrinology and metabolism, 2019, 05-01, Volume: 104, Issue:5

    Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp

2019
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
    The Journal of clinical endocrinology and metabolism, 2019, 05-01, Volume: 104, Issue:5

    Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp

2019
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
    The Journal of clinical endocrinology and metabolism, 2019, 05-01, Volume: 104, Issue:5

    Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp

2019
Phthalates Exposure as Determinant of Albuminuria in Subjects With Type 2 Diabetes: A Cross-Sectional Study.
    The Journal of clinical endocrinology and metabolism, 2019, 05-01, Volume: 104, Issue:5

    Topics: Aged; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Environmental Exp

2019
Association between phthalate exposure and glycosylated hemoglobin, fasting glucose, and type 2 diabetes mellitus: A case-control study in China.
    The Science of the total environment, 2019, Jun-20, Volume: 670

    Topics: Aged; Blood Glucose; China; Diabetes Mellitus, Type 2; Environmental Exposure; Environmental Polluta

2019
Toxicological assessment of phthalates and their alternatives using human keratinocytes.
    Environmental research, 2019, Volume: 175

    Topics: Diabetes Mellitus, Type 2; Dibutyl Phthalate; Environmental Pollutants; Humans; Keratinocytes; Phtha

2019
Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008.
    Environmental health : a global access science source, 2014, Feb-05, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Black People; Blood Glucose; Child; Diabetes Mellitus, Type 2; Endocrine Di

2014
Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: a prospective investigation in the Nurses' Health Study (NHS) and NHSII cohorts.
    Environmental health perspectives, 2014, Volume: 122, Issue:6

    Topics: Aged; Benzhydryl Compounds; Body Mass Index; Diabetes Mellitus, Type 2; Environmental Exposure; Envi

2014
Influence of phthalates on glucose homeostasis and atherosclerosis in hyperlipidemic mice.
    BMC endocrine disorders, 2015, Apr-02, Volume: 15

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Endocrine Dis

2015
Diabetic Risk Factors Promote Islet Amyloid Polypeptide Misfolding by a Common, Membrane-mediated Mechanism.
    Scientific reports, 2016, 08-17, Volume: 6

    Topics: Circular Dichroism; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Membranes; Microsc

2016
Urine Levels of Phthalate Metabolites and Bisphenol A in Relation to Main Metabolic Syndrome Components: Dyslipidemia, Hypertension and Type 2 Diabetes. A Pilot Study.
    Central European journal of public health, 2016, Volume: 24, Issue:4

    Topics: Benzhydryl Compounds; Biomarkers; Chromatography, High Pressure Liquid; Czech Republic; Diabetes Mel

2016