phthalic acid has been researched along with Breast Neoplasms in 25 studies
phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Breast cancer is the most common cancer and the second leading cause of cancer-related death amongst American women." | 6.72 | The Association of Bisphenol A and Phthalates with Risk of Breast Cancer: A Meta-Analysis. ( Bi, Y; Cai, W; Jiang, H; Liu, G; Liu, H; Wang, H, 2021) |
| " Since bisphenol A (BPA) and phthalates are epigenetically toxic, the purpose of this study was to examine whether BPA and phthalate metabolites, including monoethyl phthalate (MEP), mono‑n‑butyl phthalate (MBP), mono‑isobutyl phthalate (MIBP), mono(2‑ethylhexyl) phthalate (MEHP), mono(2‑ethyl‑5‑hydroxyhexyl) phthalate (MEHHP), mono(2‑ethyl‑5‑carboxypentyl) phthalate (MECPP), and mono(2‑ethyl‑5‑oxohexyl) phthalate (MEOHP), have an epigenetic impact on ADAM33 and the incidence of breast cancer." | 3.88 | Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals. ( Chiu, CC; Hou, MF; Kan, JY; Liang, SS; Ou-Yang, F; Peng, CY; Tsai, EM; Wang, TN; Yang, PJ, 2018) |
| " In this study, we synthesized phthalic acid chemical probes and demonstrated differing protein-protein interactions between MCF-7 cells and MDA-MB-231 breast cancer cell lines." | 3.80 | Analysis of protein-protein interactions in MCF-7 and MDA-MB-231 cell lines using phthalic acid chemical probes. ( Liang, SS; Tsai, EM; Wang, TN, 2014) |
| " The data for its dosage exposure to induce ill-effects remains largely inconsistent." | 2.82 | Mechanism of phthalate esters in the progression and development of breast cancer. ( Chugh, H; Mughees, M; Wajid, S, 2022) |
| "Breast cancer is the most common cancer and the second leading cause of cancer-related death amongst American women." | 2.72 | The Association of Bisphenol A and Phthalates with Risk of Breast Cancer: A Meta-Analysis. ( Bi, Y; Cai, W; Jiang, H; Liu, G; Liu, H; Wang, H, 2021) |
| "The incidence rate of breast cancer for African American women has recently converged with that of non-Hispanic White women in the United States, although African Americans have a higher mortality rate due to this disease." | 2.53 | A review of hair product use on breast cancer risk in African American women. ( Adkins-Jackson, PB; Clark, P; Mitchell, E; Montgomery, S; Stiel, L, 2016) |
| "BCSCs from breast cancer cell lines (MDA-MB-231 and MCF-7) were enriched using a tumorsphere formation assay." | 1.91 | Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway. ( Cao, WS; Chen, Y; Fu, JY; Geng, SS; Li, XT; Wu, JS; Xie, CF; Zhao, MJ; Zhong, CY; Zhu, JY, 2023) |
| " The MEOHP presented as a non-monotonic dose-response (NMDR) curve, being U-shaped." | 1.72 | Association between recurrent breast cancer and phthalate exposure modified by hormone receptors and body mass index. ( Hou, MF; Hsieh, TH; Lee, YJ; Ou-Yang, F; Tsai, EM; Wang, TN; Yang, PJ, 2022) |
| "This study was undertaken to assess cytotoxic effects of selected aluminium compounds, parabens and phthalates in combination with silver nanoparticles (AgNP, 15 and 45 nm by STEM, Ag15 and Ag45, respectively) on cell lines of the human breast epithelium, normal (MCF-10A) and transformed (MDA-MB-231 and MCF-7)." | 1.56 | Cytotoxic effects in transformed and non-transformed human breast cell lines after exposure to silver nanoparticles in combination with selected aluminium compounds, parabens or phthalates. ( Celichowski, G; Cieślak, M; Domeradzka-Gajda, K; Grobelny, J; Kowalczyk, K; Puchowicz, D; Ranoszek-Soliwoda, K; Roszak, J; Smok-Pieniążek, A; Spryszyńska, S; Stępnik, M; Świercz, R; Tomaszewska, E, 2020) |
| "Risk of breast cancer, however, was not found to be significantly associated with phthalate, phthalate metabolites, and BPA in unadjusted or adjusted logistic regression models." | 1.46 | Environmental estrogen-like endocrine disrupting chemicals and breast cancer. ( Deoraj, A; Felty, Q; Morgan, M; Roy, D, 2017) |
| "The association between BDE-47 and breast cancer warrants further investigation." | 1.40 | Case-control study of breast cancer and exposure to synthetic environmental chemicals among Alaska Native women. ( Calafat, AM; Holmes, AK; Kieszak, SM; Koller, KR; Lanier, AP; Rubin, CH; Sacco, FD; Sjodin, A; Varner, DW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 14 (56.00) | 24.3611 |
| 2020's | 10 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Wolff, MS | 2 |
| Shen, J | 1 |
| Parada, H | 1 |
| Santella, RM | 1 |
| Neugut, AI | 1 |
| Chen, J | 1 |
| Teitelbaum, SL | 2 |
| Yang, PJ | 2 |
| Hou, MF | 2 |
| Ou-Yang, F | 2 |
| Hsieh, TH | 1 |
| Lee, YJ | 1 |
| Tsai, EM | 3 |
| Wang, TN | 3 |
| Mukherjee Das, A | 1 |
| Gogia, A | 1 |
| Garg, M | 1 |
| Elaiyaraja, A | 1 |
| Arambam, P | 1 |
| Mathur, S | 1 |
| Babu-Rajendran, R | 1 |
| Deo, SVS | 1 |
| Kumar, L | 1 |
| Das, BC | 1 |
| Janardhanan, R | 1 |
| Cao, WS | 1 |
| Zhao, MJ | 1 |
| Chen, Y | 1 |
| Zhu, JY | 1 |
| Xie, CF | 1 |
| Li, XT | 1 |
| Geng, SS | 1 |
| Zhong, CY | 1 |
| Fu, JY | 1 |
| Wu, JS | 1 |
| Chen, FP | 1 |
| Chien, MH | 1 |
| Lee, CH | 1 |
| Jenkins, H | 1 |
| MacLean, L | 1 |
| McClean, S | 1 |
| Cooke, G | 1 |
| Devereux, M | 1 |
| Howe, O | 1 |
| Pereira, MD | 1 |
| May, NV | 1 |
| Enyedy, ÉA | 1 |
| Creaven, BS | 1 |
| Kim, CE | 1 |
| Binder, AM | 1 |
| Corvalan, C | 1 |
| Pereira, A | 1 |
| Shepherd, J | 1 |
| Calafat, AM | 5 |
| Botelho, JC | 1 |
| Hampton, JM | 1 |
| Trentham-Dietz, A | 1 |
| Michels, KB | 1 |
| Roszak, J | 1 |
| Smok-Pieniążek, A | 1 |
| Spryszyńska, S | 1 |
| Kowalczyk, K | 1 |
| Domeradzka-Gajda, K | 1 |
| Świercz, R | 1 |
| Grobelny, J | 1 |
| Tomaszewska, E | 1 |
| Ranoszek-Soliwoda, K | 1 |
| Celichowski, G | 1 |
| Cieślak, M | 1 |
| Puchowicz, D | 1 |
| Stępnik, M | 1 |
| Mughees, M | 1 |
| Chugh, H | 1 |
| Wajid, S | 1 |
| Liu, G | 1 |
| Cai, W | 1 |
| Liu, H | 1 |
| Jiang, H | 1 |
| Bi, Y | 1 |
| Wang, H | 1 |
| Zuccarello, P | 1 |
| Oliveri Conti, G | 1 |
| Cavallaro, F | 1 |
| Copat, C | 1 |
| Cristaldi, A | 1 |
| Fiore, M | 1 |
| Ferrante, M | 1 |
| Liang, SS | 2 |
| Chiu, CC | 1 |
| Kan, JY | 1 |
| Peng, CY | 1 |
| Reeves, KW | 1 |
| Díaz Santana, M | 1 |
| Manson, JE | 1 |
| Hankinson, SE | 1 |
| Zoeller, RT | 1 |
| Bigelow, C | 1 |
| Sturgeon, SR | 1 |
| Spiegelman, D | 1 |
| Tinker, L | 1 |
| Luo, J | 1 |
| Chen, B | 1 |
| Meliker, J | 1 |
| Bonner, MR | 1 |
| Cote, ML | 1 |
| Cheng, TD | 1 |
| Crobeddu, B | 1 |
| Ferraris, E | 1 |
| Kolasa, E | 1 |
| Plante, I | 1 |
| Ahern, TP | 1 |
| Broe, A | 1 |
| Lash, TL | 1 |
| Cronin-Fenton, DP | 1 |
| Ulrichsen, SP | 1 |
| Christiansen, PM | 1 |
| Cole, BF | 1 |
| Tamimi, RM | 1 |
| Sørensen, HT | 1 |
| Damkier, P | 1 |
| Kantor, ED | 1 |
| Romano, ME | 1 |
| Mervish, N | 1 |
| McGovern, KJ | 1 |
| Pinney, SM | 1 |
| Windham, GC | 1 |
| Biro, FM | 1 |
| Kushi, LH | 1 |
| Silva, MJ | 1 |
| Ye, X | 1 |
| Holmes, AK | 1 |
| Koller, KR | 1 |
| Kieszak, SM | 1 |
| Sjodin, A | 1 |
| Sacco, FD | 1 |
| Varner, DW | 1 |
| Lanier, AP | 1 |
| Rubin, CH | 1 |
| Stiel, L | 1 |
| Adkins-Jackson, PB | 1 |
| Clark, P | 1 |
| Mitchell, E | 1 |
| Montgomery, S | 1 |
| Mérida-Ortega, Á | 1 |
| Hernández-Alcaraz, C | 1 |
| Hernández-Ramírez, RU | 2 |
| García-Martínez, A | 1 |
| Trejo-Valdivia, B | 1 |
| Salinas-Rodríguez, A | 1 |
| Svensson, K | 1 |
| Cebrián, ME | 2 |
| Franco-Marina, F | 1 |
| López-Carrillo, L | 2 |
| Morgan, M | 1 |
| Deoraj, A | 1 |
| Felty, Q | 1 |
| Roy, D | 1 |
| Torres-Sánchez, L | 1 |
| Galván-Portillo, M | 1 |
| Needham, LL | 1 |
| Ruiz-Ramos, R | 1 |
| Witorsch, RJ | 1 |
| Thomas, JA | 1 |
| Okubo, T | 1 |
| Suzuki, T | 1 |
| Yokoyama, Y | 1 |
| Kano, K | 1 |
| Kano, I | 1 |
5 reviews available for phthalic acid and Breast Neoplasms
| Article | Year |
|---|---|
Mechanism of phthalate esters in the progression and development of breast cancer.
Topics: Breast Neoplasms; Endocrine Disruptors; Esters; Female; Humans; Phthalic Acids | 2022 |
The Association of Bisphenol A and Phthalates with Risk of Breast Cancer: A Meta-Analysis.
Topics: Benzhydryl Compounds; Breast Neoplasms; Environmental Exposure; Environmental Pollutants; Female; Hu | 2021 |
Implication of dietary phthalates in breast cancer. A systematic review.
Topics: Breast Neoplasms; Diet; Environmental Exposure; Female; Humans; Phthalic Acids | 2018 |
A review of hair product use on breast cancer risk in African American women.
Topics: Black or African American; Breast Neoplasms; Environmental Exposure; Estrogens; Female; Hair Prepara | 2016 |
Personal care products and endocrine disruption: A critical review of the literature.
Topics: Animals; Breast Neoplasms; Carbanilides; Carcinoma, Ductal, Breast; Cosmetics; Endocrine Disruptors; | 2010 |
20 other studies available for phthalic acid and Breast Neoplasms
| Article | Year |
|---|---|
Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project.
Topics: Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Environmental Exposure; Female; Humans; L | 2022 |
Association between recurrent breast cancer and phthalate exposure modified by hormone receptors and body mass index.
Topics: Adult; Aged; Body Mass Index; Breast Neoplasms; Environmental Exposure; Female; Humans; Middle Aged; | 2022 |
Urinary concentration of endocrine-disrupting phthalates and breast cancer risk in Indian women: A case-control study with a focus on mutations in phthalate-responsive genes.
Topics: Breast Neoplasms; Case-Control Studies; Dibutyl Phthalate; Diethylhexyl Phthalate; Female; Genetic P | 2022 |
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Hedgehog Proteins; Humans; Neoplastic Stem Cells; Oncoge | 2023 |
Regulation of the cell cycle and P13K/AKT/mTOR signaling pathway by phthalates in normal human breast cells.
Topics: Breast Neoplasms; Cell Division; Cyclin A; Dibutyl Phthalate; Diethylhexyl Phthalate; Female; Humans | 2023 |
Structural and solution speciation studies on selected [Cu(NN)(OO)] complexes and an investigation of their biomimetic activity, ROS generation and their cytotoxicity in normoxic, hypoxic and anoxic environments in MCF-7 breast cancer-derived cells.
Topics: Antineoplastic Agents; Biomimetics; Breast Neoplasms; Coordination Complexes; Copper; Female; Humans | 2023 |
Time-specific impact of mono-benzyl phthalate (MBzP) and perfluorooctanoic acid (PFOA) on breast density of a Chilean adolescent Cohort.
Topics: Adolescent; Breast Density; Breast Neoplasms; Chile; Cohort Studies; Female; Humans; Phthalic Acids | 2023 |
Cytotoxic effects in transformed and non-transformed human breast cell lines after exposure to silver nanoparticles in combination with selected aluminium compounds, parabens or phthalates.
Topics: Aluminum Compounds; Breast Neoplasms; Cell Cycle; Cell Line; Cell Survival; Drug Interactions; Femal | 2020 |
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals.
Topics: ADAM Proteins; Adult; Aged; Benzhydryl Compounds; Breast Neoplasms; Case-Control Studies; Chromatogr | 2018 |
Urinary Phthalate Biomarker Concentrations and Postmenopausal Breast Cancer Risk.
Topics: Aged; Biomarkers; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Creatinine; Disease Sus | 2019 |
Di(2-ethylhexyl) phthalate (DEHP) increases proliferation of epithelial breast cancer cells through progesterone receptor dysregulation.
Topics: Breast Neoplasms; Cell Proliferation; Diethylhexyl Phthalate; Humans; Phthalic Acids; Receptors, Pro | 2019 |
Phthalate Exposure and Breast Cancer Incidence: A Danish Nationwide Cohort Study.
Topics: Breast Neoplasms; Cohort Studies; Denmark; Female; Humans; Incidence; Phthalic Acids | 2019 |
Phthalate Exposure From Prescription Medications and Breast Cancer Risk.
Topics: Breast Neoplasms; Cohort Studies; Denmark; Humans; Phthalic Acids | 2019 |
Dietary predictors of urinary environmental biomarkers in young girls, BCERP, 2004-7.
Topics: Benzhydryl Compounds; Biomarkers; Breast Neoplasms; Child; Diet; Environmental Exposure; Environment | 2014 |
Analysis of protein-protein interactions in MCF-7 and MDA-MB-231 cell lines using phthalic acid chemical probes.
Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Female; Humans; MCF-7 Cells; Phthalic Acids; Protein Int | 2014 |
Case-control study of breast cancer and exposure to synthetic environmental chemicals among Alaska Native women.
Topics: Adult; Aged; Aged, 80 and over; Alaska; Analysis of Variance; Breast Neoplasms; Case-Control Studies | 2014 |
Phthalate exposure, flavonoid consumption and breast cancer risk among Mexican women.
Topics: Breast Neoplasms; Case-Control Studies; Chromatography, High Pressure Liquid; Diethylhexyl Phthalate | 2016 |
Environmental estrogen-like endocrine disrupting chemicals and breast cancer.
Topics: Adult; Aged; Benzhydryl Compounds; Breast Neoplasms; Endocrine Disruptors; Environmental Pollutants; | 2017 |
Exposure to phthalates and breast cancer risk in northern Mexico.
Topics: Breast Neoplasms; Case-Control Studies; Environmental Exposure; Female; Humans; Mexico; Middle Aged; | 2010 |
Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line, Tumor; Dose-Response Re | 2003 |