Page last updated: 2024-10-20

phthalic acid and Asthma

phthalic acid has been researched along with Asthma in 45 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies."4.31Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood. ( Doherty, DA; Foong, RE; Franklin, P; Hall, GL; Hart, RJ; Keelan, JA; Sanna, F; Sly, PD; Thorstensen, EB, 2023)
"We quantified urinary concentrations of eight phthalate metabolites and bisphenol A in mothers twice during pregnancy in 1999-2000 in Salinas, California."3.91Prenatal high molecular weight phthalates and bisphenol A, and childhood respiratory and allergic outcomes. ( Balmes, J; Berger, K; Calafat, AM; Eskenazi, B; Harley, KG; Holland, N; Kogut, K, 2019)
" A dose-response relationship was found between concentrations of DiBP in dust and asthma."1.72Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China. ( Hou, J; Sun, Y; Wang, P; Zhang, Q; Zhao, Y; Zhu, C, 2022)
" Furthermore, dose-response relationships for these associations are supported by trend analyses."1.32The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study. ( Bornehag, CG; Hägerhed-Engman, L; Hasselgren, M; Lundgren, B; Sigsgaard, T; Sundell, J; Weschler, CJ, 2004)
"Formaldehyde is a widely used irritating chemical, mainly employed as disinfectant or in the production of multiple resin products employed in the wood, shoe, and clothing industries."1.27Occupational asthma secondary to low molecular weight agents used in the plastic and resin industries. ( Andrach, RH; Bardana, EJ, 1983)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.67)18.7374
1990's0 (0.00)18.2507
2000's2 (4.44)29.6817
2010's17 (37.78)24.3611
2020's23 (51.11)2.80

Authors

AuthorsStudies
Preece, AS2
Knutz, M2
Lindh, CH1
Bornehag, CG6
Shu, H3
Lee, JY1
Lee, J1
Huh, DA1
Moon, KW1
Fandiño-Del-Rio, M2
Matsui, EC1
Peng, RD1
Meeker, JD1
Quirós-Alcalá, L2
Zhu, C2
Sun, Y3
Zhao, Y2
Hou, J2
Zhang, Q2
Wang, P1
Babadi, RS2
Riederer, AM2
Sampson, PD2
Sathyanarayana, S3
Kavanagh, TJ2
Krenz, JE2
Andra, SS2
Kim-Schulze, S2
Jansen, KL2
Torres, E2
Perez, A2
Younglove, LR2
Tchong-French, MI2
Karr, CJ3
Wang, JQ1
Liang, CM1
Hu, YB1
Xia, X1
Li, ZJ1
Gao, H1
Sheng, J1
Huang, K1
Wang, SF1
Zhu, P1
Hao, JH1
Tao, FB1
Dalton, KR1
Louis, LM1
Garza, MA1
Davis, MF1
Foong, RE1
Franklin, P1
Sanna, F1
Hall, GL1
Sly, PD1
Thorstensen, EB1
Doherty, DA1
Keelan, JA1
Hart, RJ1
Zhang, Y2
Ataei, Y2
Han, Y1
Yu, X1
Lu, Y1
Shen, Y1
Wang, X1
Wei, H1
Ni, K1
Qu, J1
Chen, G1
Liu, W2
S Ellie, A1
Dong, H1
Ahmad, UM1
Kim, SH1
Quoc, QL1
Park, HS1
Shin, YS1
Özel, F1
Stratmann, M1
Lindh, C1
Gennings, C1
Rüegg, J1
Duh, TH1
Yang, CJ1
Lee, CH1
Ko, YC1
Han, Q1
Gao, X1
Wang, S1
Wei, Z1
Wang, Y1
Xu, K1
Chen, M1
Tsai, ML1
Hsu, SH1
Wang, LT1
Liao, WT1
Lin, YC1
Kuo, CH1
Hsu, YL1
Feng, MC1
Kuo, FC1
Hung, CH1
Chen, Z1
Li, F1
Fu, L1
Xia, Y1
Luo, Y1
Guo, A1
Zhu, X1
Zhong, H1
Luo, Q1
Bølling, AK1
Sripada, K1
Becher, R1
Bekö, G1
Adgent, MA1
Carroll, KN1
Hazlehurst, MF1
Loftus, CT1
Szpiro, AA1
Barrett, ES1
LeWinn, KZ1
Bush, NR1
Tylavsky, FA1
Kannan, K1
Krais, AM1
Wikström, S1
Navaranjan, G1
Diamond, ML1
Harris, SA1
Jantunen, LM1
Bernstein, S1
Scott, JA1
Takaro, TK1
Dai, R1
Lefebvre, DL1
Azad, MB1
Becker, AB1
Mandhane, PJ1
Moraes, TJ1
Simons, E1
Turvey, SE1
Sears, MR1
Subbarao, P1
Brook, JR1
Zhang, J1
Sun, C1
Lu, R1
Zou, Z1
Huang, C1
Jahreis, S1
Trump, S1
Bauer, M1
Bauer, T1
Thürmann, L1
Feltens, R1
Wang, Q1
Gu, L1
Grützmann, K1
Röder, S1
Averbeck, M1
Weichenhan, D1
Plass, C1
Sack, U1
Borte, M1
Dubourg, V1
Schüürmann, G1
Simon, JC1
von Bergen, M1
Hackermüller, J1
Eils, R1
Lehmann, I1
Polte, T1
Li, MC1
Chen, CH1
Guo, YL1
Vernet, C1
Pin, I1
Giorgis-Allemand, L1
Philippat, C1
Benmerad, M1
Quentin, J1
Calafat, AM4
Ye, X1
Annesi-Maesano, I1
Siroux, V1
Slama, R1
Strassle, PD1
Smit, LAM1
Hoppin, JA2
Berger, K2
Eskenazi, B2
Balmes, J2
Holland, N2
Harley, KG2
Kogut, K1
Lü, J1
Cheng, X1
Wang, B1
Liu, Y1
Odebeatu, CC1
Taylor, T1
Fleming, LE1
J Osborne, N1
Jönsson, BA1
Larsson, M1
Nånberg, E2
Ait Bamai, Y1
Shibata, E1
Saito, I1
Araki, A1
Kanazawa, A2
Morimoto, K1
Nakayama, K1
Tanaka, M1
Takigawa, T1
Yoshimura, T1
Chikara, H1
Saijo, Y1
Kishi, R2
Ku, HY1
Su, PH1
Wen, HJ1
Sun, HL1
Wang, CJ1
Chen, HY1
Jaakkola, JJ1
Wang, SL1
Robinson, L1
Miller, R1
Kimber, I1
Dearman, RJ1
Win-Shwe, TT1
Yanagisawa, R1
Koike, E1
Nitta, H1
Takano, H1
Bertelsen, RJ1
Carlsen, KC1
Håland, G1
Mowinckel, P1
Carlsen, KH1
Løvik, M1
Tillett, T1
MOULIES, A1
MARC, Y1
MAEDER, E1
Sundell, J1
Weschler, CJ1
Sigsgaard, T1
Lundgren, B1
Hasselgren, M1
Hägerhed-Engman, L1
Bardana, EJ1
Andrach, RH1

Reviews

7 reviews available for phthalic acid and Asthma

ArticleYear
Health Effects of Exposure to Indoor Semi-Volatile Organic Compounds in Chinese Building Environment: A Systematic Review.
    International journal of environmental research and public health, 2022, 12-30, Volume: 20, Issue:1

    Topics: Adult; Air Pollutants; Air Pollution, Indoor; Asthma; Child; China; Environmental Exposure; Humans;

2022
Phthalate exposure and allergic diseases: Review of epidemiological and experimental evidence.
    Environment international, 2020, Volume: 139

    Topics: Animals; Asthma; Environmental Exposure; Humans; Hypersensitivity; Phthalic Acids

2020
Phthalate esters and childhood asthma: A systematic review and congener-specific meta-analysis.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 229

    Topics: Air Pollutants; Asthma; Child; Diethylhexyl Phthalate; Dust; Environmental Exposure; Esters; Humans;

2017
The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: a Review of Latest Findings.
    Current environmental health reports, 2015, Volume: 2, Issue:4

    Topics: Animals; Asthma; Benzhydryl Compounds; Endocrine Disruptors; Environmental Exposure; Humans; Hyperse

2015
[Potential risk of indoor semivolatile organic compounds indoors to human health].
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 2009, Volume: 64, Issue:3

    Topics: Air Pollution, Indoor; Animals; Asthma; Dust; Humans; Hypersensitivity; Japan; Pesticides; Phthalic

2009
Phthalate exposure and asthma in children.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Adolescent; Animals; Asthma; Child; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Expo

2010
An assessment of the ability of phthalates to influence immune and allergic responses.
    Toxicology, 2010, May-27, Volume: 271, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Asthma; Europe; Female; Humans; Hypersensitivity; Injections, Intra

2010

Trials

1 trial available for phthalic acid and Asthma

ArticleYear
Longitudinal measures of phthalate exposure and asthma exacerbation in a rural agricultural cohort of Latino children in Yakima Valley, Washington.
    International journal of hygiene and environmental health, 2022, Volume: 243

    Topics: Agriculture; Asthma; Child; Environmental Exposure; Environmental Pollutants; Hispanic or Latino; Hu

2022

Other Studies

37 other studies available for phthalic acid and Asthma

ArticleYear
Prenatal phthalate exposure and early childhood wheeze in the SELMA study.
    Journal of exposure science & environmental epidemiology, 2022, Volume: 32, Issue:2

    Topics: Asthma; Child; Child, Preschool; Environmental Exposure; Environmental Pollutants; Female; Humans; M

2022
Association between environmental exposure to phthalates and allergic disorders in Korean children: Korean National Environmental Health Survey (KoNEHS) 2015-2017.
    International journal of hygiene and environmental health, 2021, Volume: 238

    Topics: Asthma; Child; Environmental Exposure; Environmental Health; Environmental Pollutants; Humans; Phtha

2021
Phthalate biomarkers and associations with respiratory symptoms and healthcare utilization among low-income urban children with asthma.
    Environmental research, 2022, Volume: 212, Issue:Pt B

    Topics: Asthma; Biomarkers; Child; Delivery of Health Care; Diethylhexyl Phthalate; Environmental Exposure;

2022
Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China.
    Chemosphere, 2022, Volume: 302

    Topics: Asthma; Child; Dust; Environmental Exposure; Humans; Hypersensitivity; Phthalic Acids; Prevalence

2022
The effect of phthalates exposure during pregnancy on asthma in infants aged 0 to 36 months: a birth cohort study.
    Environmental geochemistry and health, 2023, Volume: 45, Issue:5

    Topics: Asthma; Child; Child, Preschool; Cohort Studies; Environmental Exposure; Environmental Pollutants; F

2023
Associations between repeated measures of urinary phthalate metabolites and biomarkers of oxidative stress in a rural agricultural cohort of children with asthma.
    The Science of the total environment, 2022, Nov-20, Volume: 848

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Agriculture; Asthma; Biomarkers; Child; Diethylhexyl Phthalate; DNA; En

2022
Microbiome alterations associated with phthalate exposures in a US-based sample of Latino workers.
    Environmental research, 2022, Volume: 214, Issue:Pt 4

    Topics: Asthma; Biomarkers; Environmental Exposure; Environmental Pollutants; Ethnicity; Hispanic or Latino;

2022
Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood.
    Respirology (Carlton, Vic.), 2023, Volume: 28, Issue:3

    Topics: Asthma; Benzhydryl Compounds; Child, Preschool; Cohort Studies; Environmental Exposure; Female; Huma

2023
Phthalate Metabolites in Urine of Chinese Children and Their Association with Asthma and Allergic Symptoms.
    International journal of environmental research and public health, 2022, 10-28, Volume: 19, Issue:21

    Topics: Asthma; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Environmental Polluta

2022
Di-(2-ethylhexyl) phthalate aggravates fine particulate matter-induced asthma in weanling mice due to T follicular helper cell-dependent response.
    Toxicology, 2023, 01-15, Volume: 484

    Topics: Adjuvants, Immunologic; Allergens; Animals; Asthma; Diethylhexyl Phthalate; Female; Immunoglobulin E

2023
The effect of apigenin, an aryl hydrocarbon receptor antagonist, in Phthalate-Exacerbated eosinophilic asthma model.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:13

    Topics: Animals; Apigenin; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflamma

2023
Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study.
    Environment international, 2023, Volume: 178

    Topics: Asthma; Child; Child, Preschool; Environmental Exposure; Environmental Illness; Environmental Pollut

2023
A Study of the Relationship between Phthalate Exposure and the Occurrence of Adult Asthma in Taiwan.
    Molecules (Basel, Switzerland), 2023, Jul-05, Volume: 28, Issue:13

    Topics: Adult; Asthma; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Hum

2023
Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma through the TRPA1-p38 MAPK pathway.
    Toxicology letters, 2023, Aug-01, Volume: 384

    Topics: Animals; Asthma; Diethylhexyl Phthalate; Mice; Microplastics; Ovalbumin; p38 Mitogen-Activated Prote

2023
Di(2-ethylhexyl) phthalate mediates IL-33 production
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Asthma; Child, Preschool; Diethylhexyl Phthalate; Female; Humans; Hypersensitivity; Interle

2023
Role of inflammatory lipid and fatty acid metabolic abnormalities induced by plastic additives exposure in childhood asthma.
    Journal of environmental sciences (China), 2024, Volume: 137

    Topics: Asthma; Child; Child, Preschool; Fatty Acids; Flame Retardants; Humans; Infant; Organophosphates

2024
A combined cohort analysis of prenatal exposure to phthalate mixtures and childhood asthma.
    Environment international, 2020, Volume: 143

    Topics: Asthma; Child; Child, Preschool; Cohort Studies; Environmental Exposure; Environmental Pollutants; F

2020
Phthalate levels in indoor dust and associations to croup in the SELMA study.
    Journal of exposure science & environmental epidemiology, 2021, Volume: 31, Issue:2

    Topics: Asthma; Child; Croup; Dust; Environmental Exposure; Female; Gas Chromatography-Mass Spectrometry; Hu

2021
Early life exposure to phthalates and the development of childhood asthma among Canadian children.
    Environmental research, 2021, Volume: 197

    Topics: Asthma; Canada; Child; Cohort Studies; Environmental Exposure; Humans; Phthalic Acids

2021
Associations between phthalic acid esters in household dust and childhood asthma in Shanghai, China.
    Environmental research, 2021, Volume: 200

    Topics: Asthma; Child; China; Dust; Esters; Humans; Phthalic Acids

2021
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.
    The Journal of allergy and clinical immunology, 2018, Volume: 141, Issue:2

    Topics: Adult; Animals; Asthma; Child; Disease Models, Animal; Epigenesis, Genetic; Female; Germany; Humans;

2018
    Environmental health perspectives, 2017, 09-08, Volume: 125, Issue:9

    Topics: Asthma; Child, Preschool; Environmental Exposure; Environmental Pollutants; Female; Humans; Male; Ma

2017
Endotoxin enhances respiratory effects of phthalates in adults: Results from NHANES 2005-6.
    Environmental research, 2018, Volume: 162

    Topics: Adult; Asthma; Cross-Sectional Studies; Dust; Endotoxins; Environmental Exposure; Humans; Nutrition

2018
Associations between prenatal maternal urinary concentrations of personal care product chemical biomarkers and childhood respiratory and allergic outcomes in the CHAMACOS study.
    Environment international, 2018, Volume: 121, Issue:Pt 1

    Topics: Adolescent; Adult; Asthma; Bayes Theorem; Biomarkers; Child; Cohort Studies; Cosmetics; Eczema; Envi

2018
Prenatal high molecular weight phthalates and bisphenol A, and childhood respiratory and allergic outcomes.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2019, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Asthma; Bayes Theorem; Benzhydryl Compounds; Biomarkers; California; Child; Child

2019
[Effects of phthalate on pulmonary allergy of offspring during intrauterin and lactating exposure].
    Wei sheng yan jiu = Journal of hygiene research, 2019, Volume: 48, Issue:1

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Humans; Hypersensitiv

2019
Phthalates and asthma in children and adults: US NHANES 2007-2012.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:27

    Topics: Adolescent; Adult; Asthma; Child; Environmental Exposure; Female; Humans; Logistic Models; Longitudi

2019
PVC flooring at home and development of asthma among young children in Sweden, a 10-year follow-up.
    Indoor air, 2014, Volume: 24, Issue:3

    Topics: Asthma; Child, Preschool; Cohort Studies; Female; Floors and Floorcoverings; Follow-Up Studies; Huma

2014
Exposure to house dust phthalates in relation to asthma and allergies in both children and adults.
    The Science of the total environment, 2014, Jul-01, Volume: 485-486

    Topics: Adolescent; Adult; Air Pollutants; Air Pollution, Indoor; Asthma; Child; Child, Preschool; Dust; Env

2014
Prenatal and postnatal exposure to phthalate esters and asthma: a 9-year follow-up study of a taiwanese birth cohort.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adult; Asthma; Child; Child, Preschool; Cohort Studies; Environmental Exposure; Esters; Female; Foll

2015
Expression levels of neuroimmune biomarkers in hypothalamus of allergic mice after phthalate exposure.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:10

    Topics: Allergens; Animals; Asthma; Biomarkers; Chemokine CCL3; Diethylhexyl Phthalate; Dose-Response Relati

2013
Urinary biomarkers for phthalates associated with asthma in Norwegian children.
    Environmental health perspectives, 2013, Volume: 121, Issue:2

    Topics: Asthma; Biomarkers; Body Burden; Child; Cross-Sectional Studies; Humans; Norway; Phthalic Acids

2013
Phthalates and childhood asthma: revealing an association through urinary biomarkers.
    Environmental health perspectives, 2013, Volume: 121, Issue:2

    Topics: Asthma; Biomarkers; Humans; Phthalic Acids

2013
[Asthmatic therapy and rhino-tracheo-bronchial diseases in childhood. (Therapeutic trials of ammonium phthalate)].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1961, Volume: 138

    Topics: Ammonium Compounds; Asthma; Bronchitis; Child; Disease; Humans; Infant; Phthalic Acids; Quaternary A

1961
[RHINITIS VASOMOTORICA DUE TO EPOXY RESIN HARDENERS (PHTHALIC ACID ANHYDRIDE)].
    Dermatologica, 1964, Volume: 129

    Topics: Asthma; Epoxy Resins; Humans; Maleates; Naphthoquinones; Occupational Diseases; Phthalic Acids; Phth

1964
The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study.
    Environmental health perspectives, 2004, Volume: 112, Issue:14

    Topics: Air Pollution, Indoor; Asthma; Case-Control Studies; Child; Child, Preschool; Dust; Female; Humans;

2004
Occupational asthma secondary to low molecular weight agents used in the plastic and resin industries.
    European journal of respiratory diseases, 1983, Volume: 64, Issue:4

    Topics: Asthma; Cyanates; Formaldehyde; Humans; Occupational Diseases; Phthalic Acids; Plastics; Resins, Pla

1983