Page last updated: 2024-10-20

phthalic acid and Allergic Reaction

phthalic acid has been researched along with Allergic Reaction in 28 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Research Excerpts

ExcerptRelevanceReference
"Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies."4.31Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood. ( Doherty, DA; Foong, RE; Franklin, P; Hall, GL; Hart, RJ; Keelan, JA; Sanna, F; Sly, PD; Thorstensen, EB, 2023)
"We quantified urinary concentrations of eleven phthalate metabolites, four parabens, and five other phenols in mothers twice during pregnancy and assessed probable asthma, aeroallergies, and lung function in their age seven children."3.96Prenatal phthalate, paraben, and phenol exposure and childhood allergic and respiratory outcomes: Evaluating exposure to chemical mixtures. ( Balmes, J; Berger, K; Calafat, AM; Coker, E; Eskenazi, B; Harley, K; Holland, N; Kogut, K; Rauch, S, 2020)
" A dose-response relationship was found between concentrations of DiBP in dust and asthma."1.72Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China. ( Hou, J; Sun, Y; Wang, P; Zhang, Q; Zhao, Y; Zhu, C, 2022)
"Infectious diseases were defined using questionnaires for each specified age."1.48Effects of prenatal di(2-ethylhexyl) phthalate exposure on childhood allergies and infectious diseases: The Hokkaido Study on Environment and Children's Health. ( Ait Bamai, Y; Araki, A; Kishi, R; Miyashita, C; Nakajima, T; Sasaki, S, 2018)
" Furthermore, dose-response relationships for these associations are supported by trend analyses."1.32The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study. ( Bornehag, CG; Hägerhed-Engman, L; Hasselgren, M; Lundgren, B; Sigsgaard, T; Sundell, J; Weschler, CJ, 2004)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's12 (42.86)24.3611
2020's12 (42.86)2.80

Authors

AuthorsStudies
Ketema, RM1
Ait Bamai, Y5
Miyashita, C3
Saito, T1
Kishi, R6
Ikeda-Araki, A1
Zhu, C1
Sun, Y1
Zhao, Y2
Hou, J1
Zhang, Q1
Wang, P1
Foong, RE1
Franklin, P1
Sanna, F1
Hall, GL1
Sly, PD1
Thorstensen, EB1
Doherty, DA1
Keelan, JA1
Hart, RJ1
Sung, M1
Kim, DH1
Jee, HM1
Kim, JH1
Ha, EK1
Shin, YH1
Han, MY1
Özel, F1
Stratmann, M1
Lindh, C1
Gennings, C1
Bornehag, CG4
Rüegg, J1
Tsai, ML1
Hsu, SH1
Wang, LT1
Liao, WT1
Lin, YC1
Kuo, CH1
Hsu, YL1
Feng, MC1
Kuo, FC1
Hung, CH1
Araki, A4
Bastiaensen, M1
Van den Eede, N1
Kawai, T2
Tsuboi, T2
Itoh, S1
Goudarzi, H1
Konno, S1
Covaci, A1
Berger, K2
Coker, E1
Rauch, S1
Eskenazi, B2
Balmes, J2
Kogut, K1
Holland, N2
Calafat, AM2
Harley, K1
Bølling, AK1
Sripada, K1
Becher, R1
Bekö, G1
Preece, AS1
Shu, H1
Knutz, M1
Krais, AM1
Wikström, S1
Wang, WR1
Chen, NT1
Hsu, NY1
Kuo, IY1
Chang, HW1
Wang, JY1
Su, HJ1
Wan, Y1
North, ML1
Navaranjan, G1
Ellis, AK1
Siegel, JA1
Diamond, ML1
Nakajima, T1
Sasaki, S1
Harley, KG1
Lü, J1
Cheng, X1
Wang, B1
Liu, Y1
Zhang, Y1
Hoppin, JA1
Jaramillo, R1
London, SJ1
Bertelsen, RJ1
Salo, PM1
Sandler, DP1
Zeldin, DC1
Shibata, E1
Saito, I2
Kanazawa, A2
Morimoto, K1
Nakayama, K1
Tanaka, M1
Takigawa, T1
Yoshimura, T1
Chikara, H1
Saijo, Y1
Gascon, M1
Casas, M1
Morales, E1
Valvi, D1
Ballesteros-Gómez, A1
Luque, N1
Rubio, S1
Monfort, N1
Ventura, R1
Martínez, D1
Sunyer, J1
Vrijheid, M1
Chen, L1
Chen, J1
Xie, CM1
Wang, X1
Zhang, YH1
Robinson, L1
Miller, R1
Yoshioka, E1
Cong, S1
Herberth, G1
Pierzchalski, A1
Feltens, R1
Bauer, M1
Röder, S1
Olek, S1
Hinz, D1
Borte, M1
von Bergen, M1
Lehmann, I1
Nanberg, E1
Kimber, I1
Dearman, RJ1
Glue, C1
Millner, A1
Bodtger, U1
Jinquan, T1
Poulsen, LK1
Sundell, J1
Weschler, CJ1
Sigsgaard, T1
Lundgren, B1
Hasselgren, M1
Hägerhed-Engman, L1
Röckel, A1
Klinke, B1
Hertel, J1
Baur, X1
Thiel, C1
Abdelhamid, S1
Fiegel, P1
Walb, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (EDCs) in Women of Child-Bearing Age and Their Partners[NCT05780047]220 participants (Actual)Interventional2022-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for phthalic acid and Allergic Reaction

ArticleYear
Phthalate exposure and allergic diseases: Review of epidemiological and experimental evidence.
    Environment international, 2020, Volume: 139

    Topics: Animals; Asthma; Environmental Exposure; Humans; Hypersensitivity; Phthalic Acids

2020
The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: a Review of Latest Findings.
    Current environmental health reports, 2015, Volume: 2, Issue:4

    Topics: Animals; Asthma; Benzhydryl Compounds; Endocrine Disruptors; Environmental Exposure; Humans; Hyperse

2015
[Potential risk of indoor semivolatile organic compounds indoors to human health].
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 2009, Volume: 64, Issue:3

    Topics: Air Pollution, Indoor; Animals; Asthma; Dust; Humans; Hypersensitivity; Japan; Pesticides; Phthalic

2009
Phthalate exposure and asthma in children.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Adolescent; Animals; Asthma; Child; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Expo

2010
An assessment of the ability of phthalates to influence immune and allergic responses.
    Toxicology, 2010, May-27, Volume: 271, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Asthma; Europe; Female; Humans; Hypersensitivity; Injections, Intra

2010

Other Studies

23 other studies available for phthalic acid and Allergic Reaction

ArticleYear
Phthalates mixture on allergies and oxidative stress biomarkers among children: The Hokkaido study.
    Environment international, 2022, Volume: 160

    Topics: Bayes Theorem; Biomarkers; Child; Environmental Exposure; Environmental Pollutants; Humans; Hypersen

2022
Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China.
    Chemosphere, 2022, Volume: 302

    Topics: Asthma; Child; Dust; Environmental Exposure; Humans; Hypersensitivity; Phthalic Acids; Prevalence

2022
Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood.
    Respirology (Carlton, Vic.), 2023, Volume: 28, Issue:3

    Topics: Asthma; Benzhydryl Compounds; Child, Preschool; Cohort Studies; Environmental Exposure; Female; Huma

2023
Urine phthalate levels were associated with skin barrier dysfunction and atopic sensitization in children.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:7

    Topics: Child; Dermatitis, Atopic; Humans; Hypersensitivity; Immunoglobulin E; Phthalic Acids

2023
Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study.
    Environment international, 2023, Volume: 178

    Topics: Asthma; Child; Child, Preschool; Environmental Exposure; Environmental Illness; Environmental Pollut

2023
Di(2-ethylhexyl) phthalate mediates IL-33 production
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Asthma; Child, Preschool; Diethylhexyl Phthalate; Female; Humans; Hypersensitivity; Interle

2023
Combined exposure to phthalate esters and phosphate flame retardants and plasticizers and their associations with wheeze and allergy symptoms among school children.
    Environmental research, 2020, Volume: 183

    Topics: Child; Environmental Exposure; Esters; Flame Retardants; Humans; Hypersensitivity; Phosphates; Phtha

2020
Prenatal phthalate, paraben, and phenol exposure and childhood allergic and respiratory outcomes: Evaluating exposure to chemical mixtures.
    The Science of the total environment, 2020, Jul-10, Volume: 725

    Topics: Bayes Theorem; Child; Environmental Exposure; Environmental Pollutants; Female; Humans; Hypersensiti

2020
Phthalate levels in indoor dust and associations to croup in the SELMA study.
    Journal of exposure science & environmental epidemiology, 2021, Volume: 31, Issue:2

    Topics: Asthma; Child; Croup; Dust; Environmental Exposure; Female; Gas Chromatography-Mass Spectrometry; Hu

2021
Associations among phthalate exposure, DNA methylation of TSLP, and childhood allergy.
    Clinical epigenetics, 2021, 04-09, Volume: 13, Issue:1

    Topics: Child; Cytokines; DNA Methylation; Female; Humans; Hypersensitivity; Male; Phthalic Acids

2021
Indoor exposure to phthalates and polycyclic aromatic hydrocarbons (PAHs) to Canadian children: the Kingston allergy birth cohort.
    Journal of exposure science & environmental epidemiology, 2022, Volume: 32, Issue:1

    Topics: Birth Cohort; Canada; Child; Dust; Humans; Hypersensitivity; Phthalic Acids; Polycyclic Aromatic Hyd

2022
Effects of prenatal di(2-ethylhexyl) phthalate exposure on childhood allergies and infectious diseases: The Hokkaido Study on Environment and Children's Health.
    The Science of the total environment, 2018, Mar-15, Volume: 618

    Topics: Child; Communicable Diseases; Environmental Pollutants; Female; Humans; Hypersensitivity; Japan; Mal

2018
Associations between prenatal maternal urinary concentrations of personal care product chemical biomarkers and childhood respiratory and allergic outcomes in the CHAMACOS study.
    Environment international, 2018, Volume: 121, Issue:Pt 1

    Topics: Adolescent; Adult; Asthma; Bayes Theorem; Biomarkers; Child; Cohort Studies; Cosmetics; Eczema; Envi

2018
[Effects of phthalate on pulmonary allergy of offspring during intrauterin and lactating exposure].
    Wei sheng yan jiu = Journal of hygiene research, 2019, Volume: 48, Issue:1

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Humans; Hypersensitiv

2019
Phthalate exposure and allergy in the U.S. population: results from NHANES 2005-2006.
    Environmental health perspectives, 2013, Volume: 121, Issue:10

    Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Hypersens

2013
Exposure to house dust phthalates in relation to asthma and allergies in both children and adults.
    The Science of the total environment, 2014, Jul-01, Volume: 485-486

    Topics: Adolescent; Adult; Air Pollutants; Air Pollution, Indoor; Asthma; Child; Child, Preschool; Dust; Env

2014
Prenatal exposure to bisphenol A and phthalates and childhood respiratory tract infections and allergy.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:2

    Topics: Benzhydryl Compounds; Child; Child, Preschool; Environmental Exposure; Female; Humans; Hypersensitiv

2015
Maternal Disononyl Phthalate Exposure Activates Allergic Airway Inflammation via Stimulating the Phosphoinositide 3-kinase/Akt Pathway in Rat Pups.
    Biomedical and environmental sciences : BES, 2015, Volume: 28, Issue:3

    Topics: Animals; Blotting, Western; Bronchitis; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Dr

2015
Exposure to phthalates in house dust and associated allergies in children aged 6-12years.
    Environment international, 2016, Volume: 96

    Topics: Child; Dermatitis, Atopic; Diethylhexyl Phthalate; Dust; Environmental Exposure; Environmental Pollu

2016
Prenatal phthalate exposure associates with low regulatory T-cell numbers and atopic dermatitis in early childhood: Results from the LINA mother-child study.
    The Journal of allergy and clinical immunology, 2017, Volume: 139, Issue:4

    Topics: Child, Preschool; Cohort Studies; Dermatitis, Atopic; Female; Humans; Hypersensitivity; Infant; Male

2017
In vitro effects of monophthalates on cytokine expression in the monocytic cell line THP-1 and in peripheral blood mononuclear cells from allergic and non-allergic donors.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:6

    Topics: Cell Line; Cytokines; Gene Expression Regulation; Humans; Hypersensitivity; Monocytes; Phthalic Acid

2002
The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study.
    Environmental health perspectives, 2004, Volume: 112, Issue:14

    Topics: Air Pollution, Indoor; Asthma; Case-Control Studies; Child; Child, Preschool; Dust; Female; Humans;

2004
Allergy to dialysis materials.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:7

    Topics: Complement Activation; Cyanates; Eosinophilia; Ethylene Oxide; Formaldehyde; Humans; Hypersensitivit

1989