phosphotyrosine has been researched along with Obesity in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, RJ; Dittmann, A; Kennedy, NJ; Mana, MD; Morshed, N; Soltero, NL; White, FM; Yilmaz, ÖH | 1 |
| Du, X; Hu, JP; Huang, K; Li, Y; Liu, JZ; Nie, F; Tang, YB; Tian, JY; Xiao, Z; Ye, F; Zhang, SE | 1 |
| Daniel, H; Ecker, J; Giesbertz, P; Höfle, AS; Padberg, I; Rein, D; Spanier, B | 1 |
| Dhar-Mascareno, M; Kral, JG; Mascareno, EJ; Ramirez, SN; Rouille, Y; Rozenberg, I | 1 |
| Baculikova, M; Fiala, R; Jezova, D; Macho, L; Zorad, S | 1 |
| Berger, J; Dallas-Yang, Q; Doebber, T; Jiang, G; Li, Z; Liu, F; Moller, DE; Shen, X; Szalkowski, D; Wu, M; Zhang, BB; Zhou, G | 1 |
| Brozinick, JT; Dohm, GL; Roberts, BR | 1 |
| Ide, T; Mochizuki, T; Murakami, K; Tsunoda, M | 1 |
| Chen, RH; Fan, HQ; Fei, L; Guo, M; Guo, XR; Liu, F; Ni, YH; Pan, XQ; Wang, B; Zhang, M | 1 |
| Budavari, A; Hotamisligil, GS; Murray, D; Spiegelman, BM | 1 |
| Carey, J; Dohm, GL; Giorgino, F; Goodyear, LJ; Sherman, LA; Smith, RJ | 1 |
| Livingston, JN; Moss, A; Moxley, RT; Unger, JW | 1 |
| Hayakawa, T; Ikeda, H; Morimoto, T; Shii, K; Shiraki, T | 1 |
| Emilsson, V; Hansson, A; Islam, MS; Morton, NM | 1 |
| Bedol, D; Ernsberger, P; Farrell, CJ; Friedman, JE; Ishizuka, T; Kaung, HL; Koletsky, RJ; Liu, S | 1 |
| Brenelli, SL; Carvalho, CR; Carvalho, DS; Saad, MJ; Villaça, V | 1 |
| Chan, CC; Cheng, A; Collins, S; Cromlish, W; Elchebly, M; Gresser, MJ; Himms-Hagen, J; Kennedy, BP; Loy, AL; Michaliszyn, E; Normandin, D; Payette, P; Ramachandran, C; Tremblay, ML | 1 |
| Le Marchand-Brustel, Y | 1 |
| Catalano, PM; Friedman, JE; Ruyter, I; Shao, J; Smith, S; Yamashita, H; Youngren, J | 1 |
| Eckel, J; Till, M; Uphues, I | 1 |
| Ménard, B; Nicod, P; Vollenweider, P | 1 |
| Brillon, DJ; Freidenberg, GR; Henry, RR; Olefsky, JM | 1 |
1 review(s) available for phosphotyrosine and Obesity
| Article | Year |
|---|---|
Molecular mechanisms of insulin action in normal and insulin-resistant states.
Topics: Animals; Aurothioglucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Mice; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine | 1999 |
21 other study(ies) available for phosphotyrosine and Obesity
| Article | Year |
|---|---|
High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network.
Topics: Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proteomics; Rats; Reactive Oxygen Species; Signal Transduction; src-Family Kinases | 2019 |
3-Phenylpropanoic acid-based phosphotyrosine (pTyr) mimetics: hit evolution to a novel orally active protein tyrosine phosphatase 1B (PTP1B) inhibitor.
Topics: Animals; Biomimetic Materials; Biomimetics; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mice; Molecular Structure; Obesity; Phenylpropionates; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Structure-Activity Relationship | 2014 |
Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Fatty Acids; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Glyoxylates; Insulin Resistance; Leptin; Liver; Lysine; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity; Phosphotyrosine; Signal Transduction; Sorbitol | 2015 |
Hexim1, a Novel Regulator of Leptin Function, Modulates Obesity and Glucose Disposal.
Topics: 3T3 Cells; Adipogenesis; Animals; Arcuate Nucleus of Hypothalamus; Diet, High-Fat; Glucose; Glucose Transporter Type 4; Haploinsufficiency; HEK293 Cells; Heterozygote; Humans; Janus Kinase 2; Leptin; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phosphotyrosine; RNA-Binding Proteins; Signal Transduction; STAT3 Transcription Factor; Transcription Factors; Weight Gain | 2016 |
Rats with monosodium glutamate-induced obesity and insulin resistance exhibit low expression of Galpha(i2) G-protein.
Topics: Adipocytes; Animals; Cell Membrane; Down-Regulation; GTP-Binding Protein alpha Subunit, Gi2; Insulin Resistance; Male; Obesity; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Sodium Glutamate | 2008 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.
Topics: Adult; Body Mass Index; Deoxyglucose; Enzyme Activation; Epidermal Growth Factor; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Oncogene Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction | 2003 |
Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice.
Topics: Animals; Biomarkers; Gene Expression Regulation; Insulin; Insulin Receptor Substrate Proteins; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscles; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; PPAR alpha; Pyrimidines; Receptor, Insulin; Signal Transduction | 2004 |
Identification and characterization of NYGGF4, a novel gene containing a phosphotyrosine-binding (PTB) domain that stimulates 3T3-L1 preadipocytes proliferation.
Topics: 3T3-L1 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cell Proliferation; DNA, Complementary; Gene Expression Profiling; Humans; Mice; Molecular Sequence Data; Obesity; Phenotype; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; RNA, Messenger; S Phase; Sequence Analysis; Species Specificity; Transfection | 2006 |
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Immunoglobulin G; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Muscles; Neutralization Tests; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha; Tyrosine | 1994 |
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.
Topics: Adult; Biological Transport; Biopsy; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Receptor, Insulin; Reference Values; Tyrosine | 1995 |
Phosphotyrosine-containing proteins in the CNS of obese Zucker rats are decreased in the absence of changes in the insulin receptor.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Hippocampus; Immunohistochemistry; Insulin; Male; Molecular Sequence Data; Nerve Tissue Proteins; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Prosencephalon; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Tyrosine | 1993 |
Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats.
Topics: Animals; Blood Glucose; Body Weight; Gene Expression; Hindlimb; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Male; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Rats; Rats, Mutant Strains; Rats, Wistar; Receptor, Insulin; Reference Values; Signal Transduction; Thiazoles; Thiazolidinediones; Triglycerides | 1996 |
Rat insulinoma-derived pancreatic beta-cells express a functional leptin receptor that mediates a proliferative response.
Topics: Animals; Carrier Proteins; Cell Division; DNA Replication; Insulinoma; Islets of Langerhans; Obesity; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-fos; Rats; Receptors, Cell Surface; Receptors, Cytokine; Receptors, Leptin; Tumor Cells, Cultured | 1997 |
Reduced insulin receptor signaling in the obese spontaneously hypertensive Koletsky rat.
Topics: 3-O-Methylglucose; Animals; Blood Glucose; Crosses, Genetic; Female; Glucose Tolerance Test; Glucose Transporter Type 4; Homozygote; Humans; Hypertension; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction | 1997 |
Angiotensin-converting enzyme inhibitor increases insulin-induced pp185 phosphorylation in liver and muscle of obese rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar; Receptor, Insulin | 1998 |
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Gene Targeting; Glucose Tolerance Test; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Mice; Mice, Knockout; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor, Insulin; Signal Transduction | 1999 |
Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus (GDM): evidence for increased serine/threonine phosphorylation in pregnancy a
Topics: Alkaline Phosphatase; Biopsy; Blood Glucose; Diabetes Mellitus; Diabetes, Gestational; Female; Gene Expression; Humans; Insulin; Membrane Glycoproteins; Muscle, Skeletal; Obesity; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Pregnancy; Pyrophosphatases; Receptor, Insulin | 2000 |
Cardiac insulin resistance is associated with an impaired recruitment of phosphatidylinositol 3-kinase to GLUT4 vesicles.
Topics: Animals; Glucose Transporter Type 4; Heart; Immunosorbent Techniques; Insulin; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Obesity; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Rats; Rats, Zucker | 2000 |
Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance.
Topics: Adipose Tissue; Adult; Biological Transport; Blood Glucose; Blood Pressure; Body Mass Index; Cells, Cultured; Deoxyglucose; Enzyme Activation; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Middle Aged; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptor, Insulin; Reference Values | 2002 |
Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations.
Topics: Adipose Tissue; Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Middle Aged; Obesity; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine | 1989 |