Page last updated: 2024-08-23

phosphotyrosine and Neoplasms

phosphotyrosine has been researched along with Neoplasms in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.45)	18.7374
1990's	9 (15.52)	18.2507
2000's	24 (41.38)	29.6817
2010's	18 (31.03)	24.3611
2020's	5 (8.62)	2.80

Authors

Authors	Studies
Feng, Y; Jin, X; Liu, J; Peng, P; Qu, Y; Shu, H; Wang, L; Wang, Y; Wei, M; Xia, M	1
Allen, S; Madan, LK; Welsh, CL	1
Caruso, IP; de Melo, FA; de Oliveira, LC; Dias, RVR; Leite, VBP; Moreira, GC; Pedro, RP; Sanches, MN	1
Chen, A; Cheng, ML; Hung, LM; Jiang, B; Li, Q; Li, X; Lin, D; Lin, F; Ma, H; Shih, LM; Suleman, M; Sun, D; Tang, HY; Tsau, MT; Wen, S; Xie, C; Zhang, F; Zhang, J; Zhao, W; Zhou, L	1
Bera, AK; Gan, H; Gurbani, D; Liu, Y; Park, JM; Potts, MB; Pruett-Miller, SM; Sakurada, SM; von Hoyningen-Huene, SJ; Westover, KD; Yang, SW; Zhuang, W	1
Beekhof, R; de Goeij-de Haas, RR; Dekker, H; Jiménez, CR; Knol, JC; Labots, M; Pham, TV; Piersma, SR; van der Mijn, JC; van Grieken, NCT; Verheul, HMW	1
Alečković, M; Arellano, ML; Boggon, TJ; Chen, GZ; Chen, J; Elf, S; Fan, J; Gong, W; Gu, TL; He, C; Hitosugi, T; Jin, P; Kang, HB; Kang, S; Kang, Y; Khoury, HJ; Khuri, FR; LeRoy, G; Lonial, S; Seo, JH; Shan, C; Shin, DM; Wang, Y; Xie, J; Zhang, L; Zhou, L	1
Sato, K	1
Kim, Y; Lu, F; Okada, N; Sun, H; Xiong, X; Zhang, H; Zhu, L	1
Azoubel, S; Ferreira, CV; Peppelenbosch, MP; Queiroz, KC; Souza, AC	1
Geerts, T; Göhlmann, HW; Janssen, B; King, P; Lavrijssen, T; Page, M; Perera, T; Rockx, C; Talloen, W; Versele, M	1
Ardi, VC; Conn, EM; Deryugina, EI; Hooper, JD; Kupriyanova, TA; Partridge, JJ; Quigley, JP; Wortmann, A	1
Dahlbäck, B; Gomez, MF; Hafizi, S; Sernstad, E; Swinny, JD	1
Lai, R; Li, L; Ma, Y; Wang, P; Wu, F; Young, LC	1
Xu, LH; Yu, Q; Zhang, X	1
Del Rosario, AM; White, FM	1
Bouvet, M; Bristow, JM; Cantin, GT; Edgington, TS; Hoffman, RM; Kaushal, S; Kelber, JA; Klemke, RL; Lin, R; Tran Cao, HS; Wang, W; Wang, Y; Yates, JR	1
Baggerly, K; Bogler, O; Cavenee, WK; Chumbalkar, V; Diao, L; Furnari, FB; Hawley, L; Hwang, Y; Latha, K; Maywald, R; Sawaya, R	1
Bongarzone, I; Caccia, D; Carniti, C; De Bortoli, M; Miccichè, F; Mondellini, P; Zanetti Domingues, L	1
Ahmad, R; Alam, M; Kosugi, M; Kufe, D; Uchida, Y	1
Fu, C; Kaneko, T; Li, L; Li, SS; Moran, MF; Schiller, MR; Tibiche, C; Wang, E	1
Hardy, S; Labbé, DP; Tremblay, ML	1
Butt, AM; Feng, D; Idrees, M; Lu, J; Tong, Y	1
Haura, EB	1
Bryson, BD; White, FM	1
Graeber, TG; Graham, NA; Kohli, B; Komisopoulou, E; Lo, RS; Mellinghoff, IK; Mischel, PS; Ribas, A; Tahmasian, M; Teitell, MA; Vivanco, I; Wu, H; Zhu, M	1
Blake, RA; Chan, J; Harris, D; Howlett, AR; Kiewlich, D; Le, P; Liang, C; Lipson, KE; McMahon, G; Miller, T; Patel, N; Rice, A; Sun, L; Vasile, S; Wang, X	1
Gamero, AM; Wiltrout, RH; Young, HA	1
Berg, T; Schust, J	1
Druker, BJ; Epstein, RJ; Lim, YP; Ooi, LL; Wong, CY	1
Comb, MJ; Goss, VL; Guo, A; Lee, KA; Moritz, A; Polakiewicz, RD; Rush, J; Spek, EJ; Zha, XM; Zhang, H	1
Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A	1
Chiariotti, L; Florio, T; Fusco, A; Iuliano, R; Pera, IL; Santoro, M; Schettini, G; Susini, C; Trapasso, F; Viglietto, G	1
Egeblad, M; Elenius, K; Isola, J; Junttila, TT; Laine, VJ; Määttä, JA; Peri, L; Sundvall, M	1
Drube, S; Liebmann, C; Stirnweiss, J; Valkova, C	1
Brandt, B; Buerger, H; Mikesch, JH; Roetger, A; Schier, K; Simon, R	1
Land, H; Xia, M	1
Crockett, DK; Elenitoba-Johnson, KS; Lim, MS; Schumacher, JA	1
Olson, MF	1
Gutzman, JH; Nikolai, SE; Rugowski, DE; Schuler, LA	1
Blaskovich, MA; Greedy, B; Guida, WC; Jove, R; Lawrence, HR; Lawrence, NJ; McLaughlin, MM; Sebti, SM; Siddiquee, K; Turkson, J; Yip, ML; Zhang, S	1
Ang, BK; Chen, Y; Choong, LY; Druker, BJ; Hew, CL; Li, B; Lim, S; Lim, YP; Lin, Q; Low, TY; Ray, RS; Sze, NS; Tan, YL; Toy, W; Wong, CH	1
Fu, L; Liu, J; Liu, Y; Sun, P; Wang, X; Yan, J; Yan, Q; Yu, L; Zhang, Z	1
Burke, TR	1
Hamburger, AW; Mishra, S	1
Fry, DW; Hanks, SK; Withers, BE	1
Cao, T; King, CR; Sastry, L	1
Bigner, SH; Bose, S; Giovanella, BC; Hibshoosh, H; Ittmann, M; Li, J; Liaw, D; McCombie, R; Miliaresis, C; Parsons, R; Podsypanina, K; Puc, J; Rodgers, L; Tycko, B; Wang, SI; Wigler, MH; Yen, C	1
Patarca, R	1
Akopov, SB; Bazarnova, TM; Buldyaeva, TV; Filatova, LS; Zbarsky, IB	1
Bakker, AB; Bauer, S; Lanier, LL; Phillips, JH; Song, Y; Spies, T; Wu, J	1
Serini, G	1
Freeman, AL; Kain, R; Lindberg, RA; Ogawa, K; Pasquale, EB; Pasqualini, R	1
Thornalley, PJ; Xu, K	1
Davies, MA; Jasser, SA; Koul, D; Lu, Y; Mills, GB; Shen, R; Shi, Y; Yung, WK	1
Dittmann, KH; Mayer, C; Rodemann, HP	1
Iwamura, K; Noguchi, K; Ogawa, R; Ohtsuka, M; Watanabe, Y	1
Chiado'Piat, L; Cirillo, D; Comoglio, PM; Di Renzo, MF; Giordano, S; Naldini, L	1

Reviews

9 review(s) available for phosphotyrosine and Neoplasms

Article	Year
Setting sail: Maneuvering SHP2 activity and its effects in cancer. Advances in cancer research, 2023, Volume: 160 Topics: Carcinogenesis; Cell Differentiation; Cell Transformation, Neoplastic; Humans; Neoplasms; Phosphotyrosine	2023
Cellular functions regulated by phosphorylation of EGFR on Tyr845. International journal of molecular sciences, 2013, May-23, Volume: 14, Issue:6 Topics: Animals; ErbB Receptors; Humans; Neoplasms; Phosphorylation; Phosphotyrosine	2013
From immune response to cancer: a spot on the low molecular weight protein tyrosine phosphatase. Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:7 Topics: Cell Movement; Genetic Predisposition to Disease; Humans; Immune System; Immune System Diseases; Lymphocyte Activation; Neoplasms; Phosphorylation; Phosphotyrosine; Polymorphism, Genetic; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Reactive Oxygen Species; Signal Transduction	2009
Quantifying oncogenic phosphotyrosine signaling networks through systems biology. Current opinion in genetics & development, 2010, Volume: 20, Issue:1 Topics: Mass Spectrometry; Microarray Analysis; Models, Biological; Mutation; Neoplasms; Phosphorylation; Phosphotyrosine; Signal Transduction; Systems Biology	2010
Protein tyrosine phosphatases in cancer: friends and foes! Progress in molecular biology and translational science, 2012, Volume: 106 Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Phosphotyrosine; Prenylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Structure-Activity Relationship; Sumoylation; Tumor Suppressor Proteins	2012
From modules to medicine: How modular domains and their associated networks can enable personalized medicine. FEBS letters, 2012, Aug-14, Volume: 586, Issue:17 Topics: Animals; Genomics; Genotype; Humans; Mass Spectrometry; Neoplasms; Phosphorylation; Phosphotyrosine; Precision Medicine; Protein Interaction Mapping; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteins; src Homology Domains	2012
Inactivation of Stat3 in tumor cells: releasing a brake on immune responses against cancer? Cancer cell, 2004, Volume: 5, Issue:2 Topics: Cell Division; Chemokine CCL5; Dendritic Cells; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, MHC Class II; Interleukin-10; Interleukin-6; Models, Molecular; Neoplasms; Phosphotyrosine; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes; Trans-Activators; Tumor Necrosis Factor-alpha	2004
The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy. Cellular oncology : the official journal of the International Society for Cellular Oncology, 2006, Volume: 28, Issue:5-6 Topics: Antigens, CD; CD55 Antigens; Humans; Ligands; Membrane Glycoproteins; Neoplasms; Phosphotyrosine; Receptors, G-Protein-Coupled; Signal Transduction	2006
Protein phosphorylation and dephosphorylation in physiologic and oncologic processes. Critical reviews in oncogenesis, 1996, Volume: 7, Issue:5-6 Topics: Animals; Cell Transformation, Neoplastic; Humans; Neoplasms; Oncogene Proteins; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins	1996

Other Studies

49 other study(ies) available for phosphotyrosine and Neoplasms

Article	Year
EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association. The Journal of biological chemistry, 2022, Volume: 298, Issue:9 Topics: Epidermal Growth Factor; ErbB Receptors; Humans; N-Acetylglucosaminyltransferases; Neoplasms; Phosphorylation; Phosphotyrosine; Pyruvate Kinase; STAT5 Transcription Factor; Tyrosine	2022
Unveiling Metastable Ensembles of GRB2 and the Relevance of Interdomain Communication during Folding. Journal of chemical information and modeling, 2023, 10-23, Volume: 63, Issue:20 Topics: Amino Acid Sequence; GRB2 Adaptor Protein; Neoplasms; Phosphotyrosine; Protein Binding; Signal Transduction; src Homology Domains	2023
c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3. Cell reports, 2020, 03-24, Volume: 30, Issue:12 Topics: Animals; Carcinogenesis; Colonic Neoplasms; Disease Progression; Enzyme Activation; Glycolysis; HCT116 Cells; HEK293 Cells; Humans; Mice, Inbred C57BL; Mutation; Neoplasms; Phosphofructokinase-2; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Reactive Oxygen Species	2020
The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51. PLoS biology, 2021, Volume: 19, Issue:6 Topics: Adenine; Animals; Autophagy; Beclin-1; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Enzyme Activation; Mice; Neoplasms; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Piperidines; Protein Binding; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Tacrolimus Binding Proteins	2021
Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection. Journal of proteomics, 2017, 06-06, Volume: 162 Topics: Biopsy; HCT116 Cells; Humans; Immunoprecipitation; Neoplasms; Phosphopeptides; Phosphoproteins; Phosphotyrosine; Precision Medicine; Proteomics; Reproducibility of Results; Tandem Mass Spectrometry	2017
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nature communications, 2013, Volume: 4 Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Enzyme Stability; Glyceric Acids; Glycolysis; Histidine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Neoplasms; Phosphoglycerate Mutase; Phosphorylation; Phosphotyrosine	2013
Acid sphingomyelinase is required for cell surface presentation of Met receptor tyrosine kinase in cancer cells. Journal of cell science, 2016, 11-15, Volume: 129, Issue:22 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cholesterol; Enzyme Activation; Female; Humans; Integrin beta3; Ligands; Melanoma; Membrane Glycoproteins; Neoplasms; Phosphotyrosine; Proto-Oncogene Proteins c-met; Qa-SNARE Proteins; Receptor, IGF Type 1; Signal Transduction; Sphingomyelin Phosphodiesterase; trans-Golgi Network; Viral Envelope Proteins	2016
Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout. Molecular cancer therapeutics, 2009, Volume: 8, Issue:7 Topics: Animals; Cell Line, Tumor; Drug Evaluation, Preclinical; ErbB Receptors; Gene Expression Profiling; Humans; Kinetics; Mice; Mice, Nude; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Array Analysis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Transplantation, Heterologous; Tyrosine	2009
Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Molecular cancer research : MCR, 2009, Volume: 7, Issue:8 Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Apoptosis; Cell Adhesion Molecules; Cell Membrane; Cell Shape; Chick Embryo; Disease Models, Animal; Doxorubicin; HeLa Cells; Humans; Kinetics; Male; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Phosphotyrosine; Prostatic Neoplasms; Tumor Stem Cell Assay	2009
Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effects. The international journal of biochemistry & cell biology, 2010, Volume: 42, Issue:1 Topics: Cell Compartmentation; Cell Line, Tumor; Cell Movement; Cytoplasm; Green Fluorescent Proteins; GTPase-Activating Proteins; Humans; Intercellular Signaling Peptides and Proteins; Intracellular Space; Microfilament Proteins; Microscopy, Fluorescence; Neoplasms; Phosphoric Monoester Hydrolases; Phosphotyrosine; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Reproducibility of Results; Structure-Activity Relationship; Subcellular Fractions; Tensins; Tumor Suppressor Proteins	2010
Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry. The Journal of biological chemistry, 2010, Jan-01, Volume: 285, Issue:1 Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Cell Survival; Chromatography, Affinity; Chromatography, Liquid; Enzyme Activation; Humans; Molecular Sequence Data; Mutant Proteins; Mutation; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Structure, Secondary; Protein-Tyrosine Kinases; Structure-Activity Relationship; Tandem Mass Spectrometry	2010
Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth. Molecular cancer, 2010, Jan-14, Volume: 9 Topics: Animals; Apoptosis; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colony-Forming Units Assay; Dogs; Epithelial Cells; Extracellular Matrix; Focal Adhesion Kinase 2; Gene Knockdown Techniques; Humans; Neoplasms; Phosphorylation; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Protein Binding; Signal Transduction	2010
Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jun-15, Volume: 107, Issue:24 Topics: Actins; Animals; Base Sequence; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Computational Biology; Cytoskeleton; DNA Primers; Female; Focal Adhesions; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Neoplasms; Pancreatic Neoplasms; Phosphotyrosine; Protein-Tyrosine Kinases; Proteomics; Pseudopodia; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases	2010
Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR. Journal of proteome research, 2011, Mar-04, Volume: 10, Issue:3 Topics: Animals; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms; Phosphopeptides; Phosphotyrosine; Signal Transduction; STAT5 Transcription Factor; Tandem Mass Spectrometry	2011
Secretome compartment is a valuable source of biomarkers for cancer-relevant pathways. Journal of proteome research, 2011, Sep-02, Volume: 10, Issue:9 Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cluster Analysis; Computational Biology; Dasatinib; Databases, Protein; Humans; Intracellular Space; Models, Biological; Neoplasm Proteins; Neoplasms; Phosphotyrosine; Proteome; Pyrimidines; Signal Transduction; Thiazoles; Transforming Growth Factor beta	2011
MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells. PloS one, 2011, Volume: 6, Issue:11 Topics: Aerobiosis; Amino Acid Sequence; Animals; Cell Line, Tumor; Cysteine; Down-Regulation; ErbB Receptors; Gene Silencing; Glycolysis; Humans; Molecular Sequence Data; Mucin-1; Mutant Proteins; Mutation; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyruvate Kinase; Rats	2011
The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer. Genome research, 2012, Volume: 22, Issue:7 Topics: Animals; Cell Communication; Cell Membrane; Cytoplasm; Evolution, Molecular; Humans; Models, Genetic; Neoplasms; Organ Specificity; Phosphorylation; Phosphotyrosine; Phylogeny; Protein Binding; Protein-Tyrosine Kinases; Signal Transduction; src Homology Domains	2012
Computational identification and modeling of crosstalk between phosphorylation, O-β-glycosylation and methylation of FoxO3 and implications for cancer therapeutics. International journal of molecular sciences, 2012, Volume: 13, Issue:3 Topics: Amino Acid Sequence; Forkhead Box Protein O3; Forkhead Transcription Factors; Glycosylation; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Kinases	2012
Signaling for death: tyrosine phosphorylation in the response to glucose deprivation. Molecular systems biology, 2012, Jun-26, Volume: 8 Topics: Glucose; Humans; Models, Biological; Neoplasms; Phosphotyrosine; Signal Transduction	2012
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Molecular systems biology, 2012, Jun-26, Volume: 8 Topics: Cell Death; Cell Line, Tumor; Feedback, Physiological; Focal Adhesions; Glucose; Humans; Mass Spectrometry; Mitochondria; Models, Biological; NADPH Oxidases; Neoplasms; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction	2012
Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion. Molecular cancer therapeutics, 2003, Volume: 2, Issue:11 Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Hepatocyte Growth Factor; Humans; Indoles; Models, Molecular; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Conformation; Proto-Oncogene Proteins c-met; Pyrroles; Signal Transduction	2003
A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3. Analytical biochemistry, 2004, Jul-01, Volume: 330, Issue:1 Topics: Antigens, CD; Cytokine Receptor gp130; DNA-Binding Proteins; Fluorescein; Fluorescence Polarization; Humans; Membrane Glycoproteins; Neoplasms; Peptides; Phosphotyrosine; src Homology Domains; STAT3 Transcription Factor; Trans-Activators	2004
Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Chromatography; Cytoskeleton; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Humans; Immunoblotting; Ligands; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasms; Phosphoproteins; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine	2004
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nature biotechnology, 2005, Volume: 23, Issue:1 Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Chromatography, Liquid; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Mass Spectrometry; Mice; Neoplasms; NIH 3T3 Cells; Peptides; Phosphorylation; Phosphotyrosine; Proteomics; Signal Transduction; Tyrosine	2005
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids. The American journal of pathology, 2005, Volume: 166, Issue:2 Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine	2005
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue. Oncogene, 2005, Apr-28, Volume: 24, Issue:19 Topics: Animals; Blotting, Western; Cell Adhesion; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Humans; Immunoblotting; Immunoprecipitation; Mutation; Neoplasms; Paxillin; Peptides; Phenotype; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 3; src-Family Kinases; Thyroid Gland; Thyroid Neoplasms; Transfection; Tyrosine	2005
Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth. Molecular biology of the cell, 2006, Volume: 17, Issue:1 Topics: ADAM Proteins; ADAM17 Protein; Adult; Aged; Aged, 80 and over; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Dimerization; Endopeptidases; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Ligands; Middle Aged; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Isoforms; Protein Processing, Post-Translational; Receptor, ErbB-4; Signal Transduction; Solubility	2006
Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling. Cellular signalling, 2006, Volume: 18, Issue:10 Topics: Animals; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Ligands; Matrix Metalloproteinases; Neoplasms; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Receptors, Adrenergic, beta-2; Signal Transduction; Transcriptional Activation	2006
Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility. Nature structural & molecular biology, 2007, Volume: 14, Issue:3 Topics: Animals; Cell Line, Tumor; Cell Movement; Colon; Down-Regulation; Enzyme Activation; GTPase-Activating Proteins; Humans; Mice; Models, Biological; Mutant Proteins; Neoplasms; Phosphotyrosine; Protein Transport; ras Proteins; rhoA GTP-Binding Protein; Tumor Suppressor Protein p53; Up-Regulation	2007
Evaluation of enrichment techniques for mass spectrometry: identification of tyrosine phosphoproteins in cancer cells. The Journal of molecular diagnostics : JMD, 2007, Volume: 9, Issue:2 Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cell Line, Tumor; Chromatography, Affinity; Chromatography, Liquid; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Phosphoproteins; Phosphotyrosine; Vanadates	2007
Mechanisms of tumour cell invasion and metastasis. Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:6 Topics: Cadherins; Clinical Trials as Topic; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Phosphotyrosine	2007
Stat5 activation inhibits prolactin-induced AP-1 activity: distinct prolactin-initiated signals in tumorigenesis dependent on cell context. Oncogene, 2007, Sep-20, Volume: 26, Issue:43 Topics: Cell Line, Tumor; Humans; Neoplasms; Phosphotyrosine; Prolactin; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Transcription Factor AP-1	2007
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Proceedings of the National Academy of Sciences of the United States of America, 2007, May-01, Volume: 104, Issue:18 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Cell Line; Computational Biology; DNA; Drug Evaluation, Preclinical; Gene Expression Regulation; Humans; Mice; Models, Molecular; Neoplasms; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; STAT3 Transcription Factor; Transcription, Genetic; Xenograft Model Antitumor Assays	2007
Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells. Proteomics, 2007, Volume: 7, Issue:14 Topics: Amino Acid Sequence; Cell Line, Tumor; Epidermal Growth Factor; Gefitinib; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Neoplasms; Phosphoproteins; Phosphotyrosine; Proteomics; Quinazolines; Serine Endopeptidases; Signal Transduction; Tandem Mass Spectrometry	2007
Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth. Biochimica et biophysica acta, 2008, Volume: 1783, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lewis Blood Group Antigens; Lewis X Antigen; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasms; Phosphotyrosine; RNA, Small Interfering; Transfection; Xenograft Model Antitumor Assays	2008
Protein-tyrosine kinases: potential targets for anticancer drug development. Stem cells (Dayton, Ohio), 1994, Volume: 12, Issue:1 Topics: Drug Design; Humans; Hydroquinones; Neoplasms; Phenols; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine	1994
Association of inhibition of cell growth by O-phospho-L-tyrosine with decreased tyrosine phosphorylation. Cancer letters, 1996, Apr-19, Volume: 102, Issue:1-2 Topics: 3T3 Cells; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Drug Interactions; Female; Humans; Insulin; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Receptor, ErbB-2; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine	1996
Correlations between the expression, phosphotyrosine content and enzymatic activity of focal adhesion kinase, pp125FAK, in tumor and nontransformed cells. Cancer biochemistry biophysics, 1996, Volume: 15, Issue:3 Topics: Blotting, Western; Cell Adhesion Molecules; Cell Line; Colonic Neoplasms; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Reference Values; Tumor Cells, Cultured	1996
Multiple Grb2-protein complexes in human cancer cells. International journal of cancer, 1997, Jan-17, Volume: 70, Issue:2 Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Genes, ras; GRB2 Adaptor Protein; Humans; Macromolecular Substances; Mice; Neoplasm Proteins; Neoplasms; Phosphotyrosine; Protein Binding; Proteins; Receptor, ErbB-2; src Homology Domains; Transfection; Tumor Cells, Cultured	1997
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (New York, N.Y.), 1997, Mar-28, Volume: 275, Issue:5308 Topics: Amino Acid Sequence; Brain Neoplasms; Breast Neoplasms; Chromosome Mapping; Chromosomes, Human, Pair 10; Female; Frameshift Mutation; Genes, Tumor Suppressor; Glioblastoma; Humans; Male; Microfilament Proteins; Molecular Sequence Data; Mutation; Neoplasm Transplantation; Neoplasms; Phosphoric Monoester Hydrolases; Phosphotyrosine; Prostatic Neoplasms; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; PTEN Phosphohydrolase; Sequence Deletion; Sequence Homology, Amino Acid; Tensins; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins	1997
Phosphorylation and biosynthesis of high molecular weight proteins of tumor nuclear matrix. Cell research, 1998, Volume: 8, Issue:3 Topics: Animals; Antigens, Nuclear; HeLa Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Molecular Weight; Neoplasms; Nuclear Matrix; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar	1998
An activating immunoreceptor complex formed by NKG2D and DAP10. Science (New York, N.Y.), 1999, Jul-30, Volume: 285, Issue:5428 Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Ligands; Lymphocyte Activation; Membrane Proteins; Mice; Molecular Sequence Data; Neoplasms; NK Cell Lectin-Like Receptor Subfamily K; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Receptors, Immunologic; Receptors, Natural Killer Cell; Signal Transduction; src Homology Domains; T-Lymphocytes; Tumor Cells, Cultured	1999
Loss of E-cadherin tyrosine phosphorylation in human cancers. Molecular medicine today, 1999, Volume: 5, Issue:8 Topics: beta Catenin; Cadherins; Cell Adhesion; Cytoskeletal Proteins; Humans; Neoplasms; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Kinases; Trans-Activators	1999
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene, 2000, Dec-07, Volume: 19, Issue:52 Topics: Animals; Blotting, Western; Breast Neoplasms; Capillaries; Cells, Cultured; Collagen; Drug Combinations; Endothelium, Vascular; Ephrin-A1; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Laminin; Ligands; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Phosphotyrosine; Proteins; Proteoglycans; Receptor Protein-Tyrosine Kinases; Receptor, EphA2; Sarcoma, Kaposi; Signal Transduction; Transplantation, Heterologous; Tumor Cells, Cultured	2000
Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK. British journal of cancer, 2001, Mar-02, Volume: 84, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Neoplasms; Phosphorylation; Phosphotyrosine; Signal Transduction	2001
Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity. Oncogene, 2002, Apr-04, Volume: 21, Issue:15 Topics: Amino Acid Motifs; Animals; Binding Sites; Catalytic Domain; Cell Division; Central Nervous System Neoplasms; Genes, Tumor Suppressor; Glioma; Humans; Kinetics; Mice; Mice, Nude; Mutation; Neoplasms; Phosphoric Monoester Hydrolases; Phosphotyrosine; Protein Structure, Tertiary; PTEN Phosphohydrolase; Sequence Analysis, Protein; Tumor Cells, Cultured; Tumor Suppressor Proteins	2002
O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation. International journal of cancer, 2001, Volume: 96 Suppl Topics: Blotting, Western; Cell Line, Transformed; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Mutation; Neoplasms; Phosphotyrosine; Radiation-Protective Agents; Serine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
Anti-O-phosphotyrosine antibodies in human sera. Microbiology and immunology, 1985, Volume: 29, Issue:8 Topics: Adolescent; Adult; Aged; Antibodies; Antibody Affinity; Child; Child, Preschool; Collagen Diseases; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infant; Infant, Newborn; Liver Diseases; Lung Diseases; Male; Middle Aged; Neoplasms; Nervous System Diseases; Phosphotyrosine; Tyrosine	1985
Proteins phosphorylated on tyrosine as markers of human tumor cell lines. International journal of cancer, 1987, Apr-15, Volume: 39, Issue:4 Topics: Cell Line; ErbB Receptors; Humans; Molecular Weight; Neoplasm Proteins; Neoplasms; Oncogenes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine	1987