Page last updated: 2024-08-23

phosphotyrosine and Leukemia, Myeloid, Acute

phosphotyrosine has been researched along with Leukemia, Myeloid, Acute in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (9.09)	18.7374
1990's	6 (27.27)	18.2507
2000's	7 (31.82)	29.6817
2010's	5 (22.73)	24.3611
2020's	2 (9.09)	2.80

Authors

Authors	Studies
Beekhof, R; Cloos, J; Cucchi, DGJ; Henneman, AA; Janssen, JJWM; Jimenez, CR; Knol, JC; Ossenkoppele, GJ; Pham, TV; Piersma, SR; van Alphen, C; van Meerloo, J; Verheul, HMW	1
Cloos, J; Cucchi, DGJ; Henneman, AA; Janssen, JJWM; Jimenez, CR; Knol, JC; Pham, TV; Piersma, SR; Schelfhorst, T; van Alphen, C	1
Kazi, JU; Rönnstrand, L	1
Jin, LL; McGlade, CJ; Minden, MD; Moran, MF; Taylor, P; Tong, J; Trudel, S; Wybenga-Groot, LE	1
Anahtar, M; Bar-Natan, M; Blonquist, T; Bradner, JE; Frank, DA; Giaccone, ZT; Heppler, LN; Hetz, C; Ho, VT; Jones, N; Kim, H; Kroll, Y; Liu, S; Marineau, JJ; Neuberg, D; Shaw, D; Soiffer, RJ; Stone, RM; Toniolo, PA; Walker, SR; Xiang, M; Ye, DQ	1
Bader, GD; Cavalli, FM; Helmy, M; Jin, L; Karisch, R; Minden, MD; Moran, MF; Neel, BG; St-Germain, J; Taylor, MD; Taylor, P; Tong, J	1
Askenazi, M; Griffin, JD; Jiang, J; Luckey, CJ; Marto, JA; Zhang, Y	1
Bagrintseva, K; Haferlach, T; Hiddemann, W; Schnittger, S; Schoch, C; Spiekermann, K	1
Breitenbuecher, F; Choudhary, CR; Cohen, PS; Ehninger, G; Estey, E; Feldman, E; Fischer, T; Giles, F; Gratwohl, A; Gschaidmeier, H; Huber, C; Kasper, S; Kindler, T; Klimek, V; Mueller-Tidow, C; Nimer, SD; Schiller, G; Serve, H	1
Clark, J; Cohen, P; DeAngelo, DJ; Estey, E; Fox, EA; Galinsky, I; Gilliland, DG; Grandin, W; Griffin, JD; Klimek, V; Lebwohl, D; Neuberg, D; Nimer, SD; Stone, RM; Wang, Y	1
Jing, N; Shao, H; Tweardy, DJ; Xu, X	1
Chang, Y; Chen, SS; Jiang, B; Li, JL; Liu, YR; Lu, DP; Qin, YZ; Ruan, GR; Zhu, HH	1
Bardet, V; Demur, C; Dos Santos, C; Payrastre, B; Prade-Houdellier, N; Récher, C	1
Arima, F; Iwasaki, H; Kubota, A; Niho, Y; Ohno, Y; Okamura, S; Otsuka, T; Shimoda, K	1
Hanazono, Y; Hirai, H; Iki, S; Inuo, EK; Kitagawa, S; Mimura, T; Minoda, S; Urabe, A; Yagisawa, M; Yuo, A	1
Asahi, M; Inazu, T; Nakamura, H; Saito, H; Tohyama, K; Tohyama, Y; Tsubokawa, M; Yamamura, H	1
Brizzi, MF; Dentelli, P; Ferrero, D; Lanfrancone, L; Pegoraro, L; Rosso, A	1
Hood, WF; Li, X; Monahan, JB; Polazzi, JO; Shieh, JJ; Welply, JK	1
Alai, M; Barbacid, M; Bustelo, XR; Cutler, RL; Krystal, G; Mui, AL	1
Griffin, JD; Ikeda, H; Ishikawa, J; Kanakura, Y; Kanayama, Y; Kitayama, H; Kuriu, A; Tamaki, T; Tarui, S; Yonezawa, T	1
Frank, DA; Sartorelli, AC	2

Trials

1 trial(s) available for phosphotyrosine and Leukemia, Myeloid, Acute

Article	Year
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood, 2005, Jan-01, Volume: 105, Issue:1 Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Enzyme Activation; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Phosphotyrosine; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Staurosporine	2005

Article

Year

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

Blood, 2005, Jan-01, Volume: 105, Issue:1

Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Enzyme Activation; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Phosphotyrosine; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Staurosporine

2005

Other Studies

21 other study(ies) available for phosphotyrosine and Leukemia, Myeloid, Acute

Article	Year
Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines. Molecular & cellular proteomics : MCP, 2020, Volume: 19, Issue:5 Topics: Antineoplastic Agents; Cell Line, Tumor; Cluster Analysis; Computer Simulation; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Molecular Targeted Therapy; Mutation; Phosphorylation; Phosphotyrosine; Protein Kinases; Proteome; Proteomics; Reproducibility of Results	2020
The influence of delay in mononuclear cell isolation on acute myeloid leukemia phosphorylation profiles. Journal of proteomics, 2021, 04-30, Volume: 238 Topics: Cell Separation; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Phosphotyrosine; Proteomics	2021
Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling. Molecular oncology, 2013, Volume: 7, Issue:3 Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Models, Molecular; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Interaction Maps; Protein Structure, Tertiary; Sequence Alignment; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Ubiquitination	2013
Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity. Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:3 Topics: Amino Acid Sequence; Binding Sites; Cell Line, Tumor; Conserved Sequence; Crystallography, X-Ray; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Models, Molecular; Multiple Myeloma; Phosphotyrosine; Protein Structure, Secondary; Proteomics; src Homology Domains; src-Family Kinases; Substrate Specificity	2015
Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent. Blood, 2016, 10-06, Volume: 128, Issue:14 Topics: Animals; Antineoplastic Agents; Apoptosis; Atovaquone; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytokine Receptor gp130; Disease Models, Animal; Down-Regulation; Drug Discovery; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Mice; Phosphorylation; Phosphotyrosine; STAT3 Transcription Factor; Treatment Outcome	2016
Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia. Proteomics, 2017, Volume: 17, Issue:6 Topics: Humans; Leukemia, Myeloid, Acute; Phosphorylation; Phosphotyrosine; Protein Kinases; Proteome; Proteomics; Signal Transduction	2017
A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia. Molecular & cellular proteomics : MCP, 2010, Volume: 9, Issue:5 Topics: Amino Acid Substitution; Animals; Cell Line, Tumor; Down-Regulation; fms-Like Tyrosine Kinase 3; Isotope Labeling; Janus Kinases; Leukemia, Myeloid, Acute; Ligands; Mice; Models, Biological; Mutant Proteins; Mutation; Peptides; Phosphotyrosine; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Signal Transduction; STAT5 Transcription Factor; Up-Regulation	2010
A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia. Blood, 2002, Nov-01, Volume: 100, Issue:9 Topics: Aged; Animals; Cell Division; Codon; DNA Mutational Analysis; Enzyme Inhibitors; Exons; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Humans; Indoles; Interleukin-3; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Mice; Mutagenesis, Insertional; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured	2002
Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML). Blood, 2005, Jan-01, Volume: 105, Issue:1 Topics: Animals; Cell Cycle; Cell Line; DNA-Binding Proteins; Enzyme Activation; fms-Like Tyrosine Kinase 3; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Mice; Milk Proteins; Models, Molecular; Mutation; Phosphotyrosine; Protein Structure, Tertiary; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Tyrosine	2005
Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. Journal of immunology (Baltimore, Md. : 1950), 2006, Mar-01, Volume: 176, Issue:5 Topics: Arginine; Cell Line; Computational Biology; Glutamic Acid; Humans; Leukemia, Myeloid, Acute; Ligands; Lysine; Models, Molecular; Phosphopeptides; Phosphotyrosine; Protein Binding; Receptors, Granulocyte Colony-Stimulating Factor; STAT3 Transcription Factor	2006
[Detection of phosphotyrosine in bcr-abl-positive cells with PY20 antibody and its clinical applications]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2006, Volume: 27, Issue:7 Topics: Antibodies, Monoclonal; Bone Marrow Cells; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Phosphotyrosine	2006
A critical role for Lyn in acute myeloid leukemia. Blood, 2008, Feb-15, Volume: 111, Issue:4 Topics: Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Morpholines; Oncogene Proteins, Viral; Phosphotyrosine; Reference Values; RNA, Small Interfering; Sirolimus; src-Family Kinases; U937 Cells	2008
G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils. Biochemical and biophysical research communications, 1994, Sep-15, Volume: 203, Issue:2 Topics: Cell Division; Granulocyte Colony-Stimulating Factor; Humans; Immunosorbent Techniques; Janus Kinase 2; Kinetics; Leukemia, Myeloid, Acute; Neutrophils; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Tumor Cells, Cultured; Tyrosine	1994
Tyrosine phosphorylation of vav protooncogene product in primary human myelogenous leukemic cells stimulated by granulocyte colony-stimulating factor. Biochemical and biophysical research communications, 1995, Jun-15, Volume: 211, Issue:2 Topics: Amino Acid Sequence; Antibodies; Blotting, Western; Cell Cycle Proteins; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Proto-Oncogenes; Recombinant Proteins; Tumor Cells, Cultured; Tyrosine	1995
Interleukin-3 activates Syk in a human myeloblastic leukemia cell line, AML193. European journal of biochemistry, 1997, Nov-01, Volume: 249, Issue:3 Topics: Blotting, Western; Enzyme Activation; Enzyme Precursors; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-3; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Receptors, Interleukin-3; Signal Transduction; Syk Kinase; Tumor Cells, Cultured	1997
c-Cbl tyrosine phosphorylation and subcellular localization in human primary leukemic cells. Experimental hematology, 1998, Volume: 26, Issue:13 Topics: Adaptor Proteins, Signal Transducing; Blotting, Western; GRB2 Adaptor Protein; Humans; Immunosorbent Techniques; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Nuclear Proteins; Phosphorylation; Phosphotyrosine; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; src Homology Domains; Subcellular Fractions; Ubiquitin-Protein Ligases	1998
Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors. Experimental hematology, 2001, Volume: 29, Issue:4 Topics: Animals; Antigens, CD34; Bone Marrow Cells; Cell Line; Cricetinae; Dimerization; DNA; DNA-Binding Proteins; Electrophoresis; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-3; Janus Kinase 2; Leukemia, Myeloid, Acute; Mice; Milk Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Granulocyte Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Surface Plasmon Resonance; Trans-Activators; Transfection; Tumor Cells, Cultured	2001
Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells. The Journal of biological chemistry, 1992, Sep-05, Volume: 267, Issue:25 Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Cytokines; Hematopoiesis; Hematopoietic Cell Growth Factors; Humans; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Oncogene Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins c-vav; Recombinant Proteins; Stem Cell Factor; Transfection; Tyrosine	1992
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells. Blood, 1991, Dec-01, Volume: 78, Issue:11 Topics: Blotting, Northern; Blotting, Western; Cell Division; Gene Expression; Hematopoietic Cell Growth Factors; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Phosphorylation; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Stem Cell Factor; Tumor Cells, Cultured; Tyrosine	1991
Regulation of protein phosphotyrosine content by changes in tyrosine kinase and protein phosphotyrosine phosphatase activities during induced granulocytic and monocytic differentiation of HL-60 leukemia cells. Biochemical and biophysical research communications, 1986, Oct-15, Volume: 140, Issue:1 Topics: Cell Differentiation; Cell Line; Granulocytes; Humans; Leukemia, Myeloid, Acute; Monocytes; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tyrosine	1986
Biochemical characterization of tyrosine kinase and phosphotyrosine phosphatase activities of HL-60 leukemia cells. Cancer research, 1988, Aug-01, Volume: 48, Issue:15 Topics: Adenosine Triphosphate; Cations, Divalent; Cell Line; Ethylmaleimide; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Peptides; Phosphoprotein Phosphatases; Phosphotyrosine; Polymers; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tyrosine	1988