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phosphotyrosine and Granulocytic Leukemia

phosphotyrosine has been researched along with Granulocytic Leukemia in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's8 (32.00)18.2507
2000's9 (36.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bardelli, M; Fasler-Kan, E; Gibbs, BF; Prokhorov, A; Rüegg, L; Sumbayev, VV; Varani, L1
Drexler, HG; Quentmeier, H; Reinhardt, J; Zaborski, M1
Allebach, J; Brown, P; Chen, P; Kim, KT; Levis, M; Small, D1
Eklund, EA; Horvath, E; Huang, W; Lindsey, S; Saberwal, G; Zhu, C1
Martínez-Barriocanal, A; Sayós, J1
Abe, A; Emi, N; Hayakawa, F; Kiyoi, H; Miyata, Y; Naoe, T; Okamoto, M; Towatari, M; Watamoto, K1
Gu, TL; Macneill, J; Nardone, J; Nimer, SD; Polakiewicz, RD; Popova, L; Reeves, C; Rush, J1
Chung, EJ; Kajiguchi, T; Kiyoi, H; Lee, S; Levis, MJ; Naoe, T; Neckers, L; Stine, A; Trepel, JB1
Ihle, JN; Miura, O; Yi, T; Zhang, J1
Kharbanda, S; Kufe, D; Yuan, ZM1
Feghali, CA; Wright, TM1
Barnekow, A; Büchner, T; Cassens, U; Koch, OM; Kremerskothen, J; Müller, C; Zühlsdorf, M1
Feldman, RA; Jücker, M; Schiffer, CA1
Akiyama, Y; Bessho, R; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, K1
Bonmann, M; Cassens, U; Koch, OM; Müller, C1
Kruijer, W; Schuringa, JJ; Vellenga, E; Wierenga, AT1
Asano, S; Iijima, Y; Kruh, GD; Okuda, K; Sakaki, Y; Sato, Y; Setoyama, M; Tojo, A; Tokunaga, K; Tri, NK1
Druker, B; Griffin, JD; Ikeda, H; Ishikawa, J; Kanakura, Y; Kanayama, Y; Kitayama, H; Kuriu, A; Nishiura, T; Yagura, H1
Aglietta, M; Cirillo, DM; Comoglio, PM; Gavosto, F; Naldini, L; Stacchini, A1
Arlinghaus, RB; Gallick, GE; Gutterman, JU; Keating, MJ; Kloetzer, WS; Kouttab, NM; Kurzrock, R; Maxwell, SA; Parsons, SJ; Talpaz, M1
Foulkes, JG; Frackelton, AR; Huhn, RD; Posner, MR; Rayter, SI1
Morla, AO; Richardson, JM; Wang, JY1
Evans, JP; Hoffbrand, AV; Wickremasinghe, RG1
Glazer, RI; Knode, MC; Yu, G1
Comoglio, PM; Di Renzo, MF; Gaudino, G1

Reviews

1 review(s) available for phosphotyrosine and Granulocytic Leukemia

ArticleYear
Protein tyrosine kinases associated with human malignancies.
    Annals of the New York Academy of Sciences, 1987, Volume: 511

    Topics: Antibodies, Neoplasm; Carcinoma, Small Cell; Cell Division; Cell Transformation, Neoplastic; Fusion Proteins, bcr-abl; Humans; Leukemia, Myeloid; Neoplasm Proteins; Oncogenes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Bombesin; Receptors, Cell Surface; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Tyrosine

1987

Other Studies

24 other study(ies) available for phosphotyrosine and Granulocytic Leukemia

ArticleYear
The immune receptor Tim-3 mediates activation of PI3 kinase/mTOR and HIF-1 pathways in human myeloid leukaemia cells.
    The international journal of biochemistry & cell biology, 2015, Volume: 59

    Topics: Calcium; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Galectins; Hepatitis A Virus Cellular Receptor 2; Humans; Hypoxia-Inducible Factor 1; Leukemia, Myeloid; Ligands; Membrane Proteins; Models, Biological; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Stem Cell Factor; Time Factors; TOR Serine-Threonine Kinases; Type C Phospholipases; Vascular Endothelial Growth Factor A

2015
FLT3 mutations in acute myeloid leukemia cell lines.
    Leukemia, 2003, Volume: 17, Issue:1

    Topics: Acute Disease; Base Sequence; Blotting, Western; Cell Transformation, Neoplastic; DNA-Binding Proteins; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid; Milk Proteins; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Point Mutation; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; STAT5 Transcription Factor; Tandem Repeat Sequences; Thymidine; Trans-Activators; Tumor Cells, Cultured

2003
FLT3/ITD mutation signaling includes suppression of SHP-1.
    The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7

    Topics: Acute Disease; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; fms-Like Tyrosine Kinase 3; Furans; Humans; Hydrolysis; Indoles; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Vanadates

2005
Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein.
    Molecular and cellular biology, 2006, Volume: 26, Issue:17

    Topics: Animals; Bone Marrow; Cell Differentiation; Glutamine; Humans; Interferon Regulatory Factors; Interferon-gamma; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Lysine; Mice; Mice, Inbred C57BL; Mutant Proteins; Myeloid Cells; Neurofibromin 1; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Transcriptional Activation; U937 Cells

2006
Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Sep-01, Volume: 177, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antigens, Surface; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Conserved Sequence; Hexosaminidases; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Mice; Molecular Sequence Data; Organ Specificity; Phosphorylation; Phosphotyrosine; Protein Binding; Receptors, Immunologic; Sequence Alignment; Signal Transduction; Transcription, Genetic

2006
Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.
    Leukemia, 2007, Volume: 21, Issue:3

    Topics: Acute Disease; Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Line; Drug Design; Drug Screening Assays, Antitumor; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cells; Leukemia, Myeloid; Membrane Proteins; Mice; Mice, Inbred C3H; Molecular Sequence Data; Mutant Proteins; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrimidines; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Tandem Repeat Sequences; Transfection

2007
Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia.
    Leukemia, 2007, Volume: 21, Issue:3

    Topics: Acute Disease; Biomarkers, Tumor; Cell Line, Tumor; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Humans; Leukemia, Myeloid; Neoplasm Proteins; Oncogene Proteins, Fusion; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; RNA, Small Interfering; STAT5 Transcription Factor; Translocation, Genetic

2007
FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.
    Leukemia, 2007, Volume: 21, Issue:12

    Topics: Active Transport, Cell Nucleus; Acute Disease; Animals; beta Catenin; Cell Line, Tumor; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Interleukin-3; Leukemia, Myeloid; Membrane Proteins; Mice; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Recombinant Proteins; RNA, Small Interfering; Staurosporine; Transcription, Genetic; Tyrphostins

2007
Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites.
    Blood, 1995, Jan-01, Volume: 85, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Disulfides; Erythropoietin; Immunosorbent Techniques; Interleukin-3; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Mice; Molecular Sequence Data; Peptide Fragments; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Erythropoietin; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Tyrosine

1995
1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells.
    Biochemistry, 1995, Jan-24, Volume: 34, Issue:3

    Topics: Amino Acid Sequence; CDC2 Protein Kinase; Cytarabine; Humans; In Vitro Techniques; Leukemia, Myeloid; Macromolecular Substances; Molecular Sequence Data; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; src-Family Kinases; Tumor Cells, Cultured; Tyrosine

1995
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.
    The Biochemical journal, 1995, Sep-01, Volume: 310 ( Pt 2)

    Topics: Adenosine Triphosphate; Antibodies; Base Sequence; Carcinoma, Squamous Cell; Cell Line; Cell-Free System; Cytosol; Humans; Interferon-gamma; Kinetics; Leukemia, Myeloid; Ligands; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Repetitive Sequences, Nucleic Acid; Skin Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates

1995
Rapid quantitative analysis of protein tyrosine residue phosphorylation in defined cell populations in whole blood and bone marrow aspirates.
    British journal of haematology, 1996, Volume: 94, Issue:3

    Topics: Acute Disease; Bone Marrow; Flow Cytometry; Hematologic Tests; Humans; Leukemia, Myeloid; Phosphorylation; Phosphotyrosine

1996
A tyrosine-phosphorylated protein of 140 kD is constitutively associated with the phosphotyrosine binding domain of Shc and the SH3 domains of Grb2 in acute myeloid leukemia cells.
    Blood, 1997, Mar-15, Volume: 89, Issue:6

    Topics: Acute Disease; Animals; ErbB Receptors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Mice; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; src Homology Domains; Tumor Cells, Cultured

1997
Role of protein tyrosine phosphorylation in etoposide-induced apoptosis and NF-kappa B activation.
    Biochemical pharmacology, 1998, Jan-15, Volume: 55, Issue:2

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Cytarabine; DNA Fragmentation; Etoposide; Humans; Kinetics; Lactams, Macrocyclic; Leukemia, Myeloid; NF-kappa B; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinones; Rifabutin; Tumor Cells, Cultured

1998
Flow cytometric analysis of protein phosphorylation in the hematopoetic system.
    Leukemia & lymphoma, 1998, Volume: 29, Issue:3-4

    Topics: Acute Disease; Adult; Flow Cytometry; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Lymphocytes; Monocytes; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Tyrosine

1998
Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.
    Blood, 2000, Jun-15, Volume: 95, Issue:12

    Topics: Acute Disease; Carrier Proteins; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Phosphorylation; Phosphoserine; Phosphotyrosine; Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

2000
Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG.
    Oncogene, 2002, Jun-27, Volume: 21, Issue:28

    Topics: Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Colony-Forming Units Assay; DNA-Binding Proteins; ETS Translocation Variant 6 Protein; Fibroblasts; Fusion Proteins, bcr-abl; Genes, abl; Humans; Interleukin-3; Leukemia, Myeloid; Oncogene Proteins; Phosphorylation; Phosphotyrosine; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-ets; Rats; Recombinant Proteins; Repressor Proteins; Tumor Cells, Cultured; Tyrosine

2002
Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product.
    Blood, 1991, Dec-01, Volume: 78, Issue:11

    Topics: Blotting, Northern; Cell Division; Gene Expression; Genistein; Hematopoietic Cell Growth Factors; Humans; Immunologic Techniques; Isoflavones; Leukemia, Myeloid; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Stem Cell Factor; Tumor Cells, Cultured; Tyrosine

1991
Phosphotyrosine antibodies identify the p210c-abl tyrosine kinase and proteins phosphorylated on tyrosine in human chronic myelogenous leukemia cells.
    Molecular and cellular biology, 1986, Volume: 6, Issue:5

    Topics: Amino Acids; Antibodies; Antigen-Antibody Complex; Bone Marrow; Cell Line; Fusion Proteins, bcr-abl; Humans; Leukemia, Myeloid; Neoplasm Proteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Reference Values; Tyrosine

1986
Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients.
    Cancer research, 1987, Mar-15, Volume: 47, Issue:6

    Topics: Amino Acids; Antigen-Antibody Complex; Blast Crisis; Cell Line; Humans; Leukemia, Myeloid; Molecular Weight; Peptide Mapping; Philadelphia Chromosome; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Tyrosine

1987
Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:13

    Topics: Amino Acid Sequence; Blast Crisis; Blood Proteins; Cell Line; Fusion Proteins, bcr-abl; Humans; Leukemia, Myeloid; Leukocytes; Neoplasm Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Recombinant Fusion Proteins; Recombinant Proteins; Tyrosine

1987
Reduction in protein tyrosine phosphorylation during differentiation of human leukemia cell line K-562.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Cell Differentiation; Cell Line; Hemin; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-abl; Tyrosine

1987
Tyrosine protein kinase substrates in Philadelphia-positive human chronic granulocytic leukemia derived cell lines (K562 and BV173): detection by using an immunoblotting technique.
    Leukemia, 1987, Volume: 1, Issue:6

    Topics: Humans; Immunosorbent Techniques; Leukemia, Myeloid; Molecular Weight; Neoplasm Proteins; Philadelphia Chromosome; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine

1987
Analysis of tyrosine kinase activity in cell extracts using nondenaturing polyacrylamide gel electrophoresis.
    Analytical biochemistry, 1987, Volume: 164, Issue:1

    Topics: Adenosine Triphosphate; Cell Line; Chromatography; Electrophoresis, Polyacrylamide Gel; Granulocytes; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Leukemia, Myeloid; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine

1987