phosphotyrosine has been researched along with Disease Models, Animal in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 11 (31.43) | 29.6817 |
| 2010's | 17 (48.57) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Krasovska, V; Reynolds, KE; Scott, AL | 1 |
| Davis, RJ; Dittmann, A; Kennedy, NJ; Mana, MD; Morshed, N; Soltero, NL; White, FM; Yilmaz, ÖH | 1 |
| Burden, SJ; Corrado, AD; Hattori, T; Ketavarapu, G; Koide, A; Koide, S; Leloup, N; Oury, J; Zhang, W | 1 |
| Dittmann, K; Huber, SM; Julien-Schraermeyer, S; Klumpp, D; Rodemann, HP; Schraermeyer, U; Stegen, B; Tschulakow, AV | 1 |
| Chen, L; Chen, Z; Cui, Y; Guo, X; Huang, Q; Jiang, Y; Lei, X; Su, H; Weng, J; Yu, L; Yu, S; Zhang, Y | 1 |
| Alvarez, LA; Corcionivoschi, N; Friedmacher, F; Fujiwara, N; Gosemann, JH; Puri, P | 1 |
| Chen, F; Jiang, L; Li, Z; Liu, X; Xu, Y; Zhang, C | 1 |
| Du, X; Hu, JP; Huang, K; Li, Y; Liu, JZ; Nie, F; Tang, YB; Tian, JY; Xiao, Z; Ye, F; Zhang, SE | 1 |
| Anderson, GM; Baguley, TD; Brouillette, J; Chatterjee, M; Cuny, GD; Ellman, JA; Foscue, E; Ghosh, D; Glicksman, MA; Greengard, P; Gresack, J; Kanyo, J; Kurup, P; Lam, TT; Lombroso, PJ; Nairn, AC; Ononenyi, C; Seyb, K; Tautz, L; Xu, J; Zhang, Y | 1 |
| Denhez, B; Geraldes, P; Guimond, MO; Jones, N; Lizotte, F; Takano, T | 1 |
| Chao, H; Grande, R; Harris, TE; Li, C; Li, H; Lira, V; Yan, Z | 1 |
| Rapp, UR; Sperl, B; Ulaganathan, VK; Ullrich, A | 1 |
| Brahmachari, S; Dawson, TM; Dawson, VL; Ge, P; Karuppagounder, SS; Kim, D; Ko, HS; Kumar, M; Lee, SH; Lee, Y; Mao, X; Pletnikova, O; Shin, JH; Troncoso, JC | 1 |
| Anahtar, M; Bar-Natan, M; Blonquist, T; Bradner, JE; Frank, DA; Giaccone, ZT; Heppler, LN; Hetz, C; Ho, VT; Jones, N; Kim, H; Kroll, Y; Liu, S; Marineau, JJ; Neuberg, D; Shaw, D; Soiffer, RJ; Stone, RM; Toniolo, PA; Walker, SR; Xiang, M; Ye, DQ | 1 |
| Ardi, VC; Conn, EM; Deryugina, EI; Hooper, JD; Kupriyanova, TA; Partridge, JJ; Quigley, JP; Wortmann, A | 1 |
| Dao-Feng, B; Wei, D; Xin-Long, C; Zhao-Fan, X | 1 |
| Backx, PH; deTombe, PP; Hardy, WR; Jones, N; Kabir, MG; Pasculescu, A; Pawson, T; Vanderlaan, RD | 1 |
| Frank, DA; Haque, N; Humphreys, BD; Nelson, EA; Takakura, A; Zandi-Nejad, K; Zhou, J | 1 |
| Gladding, CM; Lombroso, PJ; Milnerwood, AJ; Raymond, LA; Sepers, MD; Xu, J; Zhang, LY | 1 |
| Andoh, T; Ito, S; Katano, T; Kuraishi, Y; Mabuchi, T; Matsumura, S; Nakatsuka, T; Nakazawa, T; Nishio, N; Sasaki, A; Unezaki, S; Yamamoto, T | 1 |
| Carvalho, CR; Lima, MH; Rocha, EM; Saad, MJ; Thirone, AC; Ueno, M | 1 |
| Beggs, HE; Goebbels, S; Gorski, J; Jones, KR; Nave, KA; Reichardt, LF; Schahin-Reed, D; Sretavan, D; Zang, K | 1 |
| Nixon, RR | 1 |
| Bornmann, WG; Clarkson, B; Ilaria, RL; Tong, WP; Veach, DR; Wolff, NC | 1 |
| Nakazawa, A; Osuka, K; Tokuda, M; Usuda, N; Watanabe, Y; Yamauchi, K; Yoshida, J | 1 |
| Bumm, T; Corbin, AS; Deininger, MW; Druker, BJ; Goss, VL; Griswold, IJ; Johnson, K; Lee, KA; MacPartlin, M; Moseson, EM; O'Hare, T; Polakiewicz, RD; Smith, C; Stoffregen, EP; Wood, LJ | 1 |
| Eckert, A; Frölich, L; Gorriz, C; Maurer, K; Müller, WE; Peters, J; Schindowski, K; Schramm, U; Weinandi, T | 1 |
| McNiven, MA; Singh, VP | 1 |
| Budavari, A; Hotamisligil, GS; Murray, D; Spiegelman, BM | 1 |
| Caldwell, RB; Roque, RS | 1 |
| Begum, N; Ragolia, L | 1 |
| Blake, DJ; Davies, KE; Loh, NY; Nawrotzki, R; Ruegg, MA | 1 |
| Chen, F; Eisenberg, RA; Feuerstein, N; Madaio, M; Maldonado, M | 1 |
| de Aos, IE; Ilaria, RL; Roumiantsev, S; Van Etten, RA; Varticovski, L | 1 |
| Hirata, AE; Rojas, FA; Saad, MJ | 1 |
35 other study(ies) available for phosphotyrosine and Disease Models, Animal
| Article | Year |
|---|---|
Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3.
Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Interleukin-6; Male; Mice; Mice, Knockout; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Purinergic P2Y Receptor Agonists; Receptors, Interleukin-6; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Tenascin; Toll-Like Receptor 4; Uridine Triphosphate | 2021 |
High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network.
Topics: Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proteomics; Rats; Reactive Oxygen Species; Signal Transduction; src-Family Kinases | 2019 |
Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia.
Topics: Aging; Agrin; Animals; Animals, Newborn; Antibodies; Disease Models, Animal; Female; LDL-Receptor Related Proteins; Male; Mice; Molecular Targeted Therapy; Muscle Fibers, Skeletal; Muscle Proteins; Mutation; Myasthenic Syndromes, Congenital; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-crk; Receptor Protein-Tyrosine Kinases; Recurrence; Synapses | 2021 |
The radioprotector ortho-phospho-L-tyrosine (pTyr) attenuates the side effects of fractionated irradiation in retinoblastoma mouse models but also decreases the local tumour control.
Topics: Animals; Cell Survival; Disease Models, Animal; Dose Fractionation, Radiation; Mice; Phosphotyrosine; Radiation-Protective Agents; Retinal Neoplasms; Retinoblastoma; Tumor Suppressor Protein p53 | 2017 |
β-Catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability.
Topics: Acute Lung Injury; Adherens Junctions; Animals; beta Catenin; Capillary Permeability; Disease Models, Animal; Focal Adhesion Protein-Tyrosine Kinases; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Lung; Male; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Phosphotyrosine; Sepsis; Signal Transduction; Stress Fibers | 2019 |
Spatiotemporal alterations in Sprouty-2 expression and tyrosine phosphorylation in nitrofen-induced pulmonary hypoplasia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Nerve Tissue Proteins; Phenyl Ethers; Phosphotyrosine; Pregnancy; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; RNA, Messenger; Specific Pathogen-Free Organisms | 2013 |
Mammalian diaphanous-related formin 1 is required for motility and invadopodia formation in human U87 glioblastoma cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cortactin; Disease Models, Animal; Formins; Glioblastoma; Humans; Male; Mice; Mice, Nude; Phosphotyrosine; RNA, Small Interfering; Transfection; Wound Healing | 2014 |
3-Phenylpropanoic acid-based phosphotyrosine (pTyr) mimetics: hit evolution to a novel orally active protein tyrosine phosphatase 1B (PTP1B) inhibitor.
Topics: Animals; Biomimetic Materials; Biomimetics; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mice; Molecular Structure; Obesity; Phenylpropionates; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Structure-Activity Relationship | 2014 |
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Benzothiepins; Catalytic Domain; Cell Death; Cerebral Cortex; Cognition Disorders; Cysteine; Disease Models, Animal; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Neurons; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases, Non-Receptor; Substrate Specificity | 2014 |
Increased SHP-1 protein expression by high glucose levels reduces nephrin phosphorylation in podocytes.
Topics: Animals; Caspase 3; Cell Line; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glucose; GPI-Linked Proteins; HEK293 Cells; Humans; Insulin; Kidney Glomerulus; Membrane Proteins; Mice; Mice, Transgenic; Phosphorylation; Phosphotyrosine; Podocytes; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Receptors, IgG; Signal Transduction | 2015 |
Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells.
Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Cell Line; Deoxyglucose; Disease Models, Animal; Gene Knockdown Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice, Obese; Models, Biological; Muscle Cells; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphorylation; Phosphotyrosine; Physical Conditioning, Animal; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Urocortins | 2015 |
Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Cell Line; Cell Membrane; Disease Models, Animal; Disease Progression; Exons; Female; Gene Knock-In Techniques; Germ-Line Mutation; Humans; Lung Neoplasms; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Polymorphism, Single Nucleotide; Receptor, Fibroblast Growth Factor, Type 4; Signal Transduction; STAT3 Transcription Factor | 2015 |
Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration.
Topics: Aged; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Female; Gene Deletion; HEK293 Cells; Humans; Lewy Bodies; Male; Mice; Mice, Transgenic; Mutation; Neurites; Neurodegenerative Diseases; Neuroprotection; Parkinson Disease; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-abl | 2016 |
Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent.
Topics: Animals; Antineoplastic Agents; Apoptosis; Atovaquone; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytokine Receptor gp130; Disease Models, Animal; Down-Regulation; Drug Discovery; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Mice; Phosphorylation; Phosphotyrosine; STAT3 Transcription Factor; Treatment Outcome | 2016 |
Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Apoptosis; Cell Adhesion Molecules; Cell Membrane; Cell Shape; Chick Embryo; Disease Models, Animal; Doxorubicin; HeLa Cells; Humans; Kinetics; Male; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Phosphotyrosine; Prostatic Neoplasms; Tumor Stem Cell Assay | 2009 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Burns; C-Peptide; Disease Models, Animal; Glucose Clamp Technique; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle, Skeletal; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Serine; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2011 |
The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.
Topics: Animals; Biomechanical Phenomena; Cardiomyopathy, Dilated; Collagen; Disease Models, Animal; Extracellular Matrix Proteins; Heart; Mice; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Phosphotyrosine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2011 |
Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways.
Topics: Adult; Aminosalicylic Acids; Animals; Animals, Newborn; Benzenesulfonates; Cell Line; Cysts; Disease Models, Animal; Gene Expression; Genes, Reporter; Humans; Kidney; Mice; Mice, Knockout; Phosphorylation; Phosphotyrosine; Polycystic Kidney, Autosomal Dominant; Pyrimethamine; Signal Transduction; STAT3 Transcription Factor | 2011 |
Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model.
Topics: Animals; Calpain; Coculture Techniques; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Huntington Disease; Ion Channel Gating; Mice; Models, Biological; Neostriatum; Neurons; Phosphorylation; Phosphotyrosine; Protein Transport; Protein Tyrosine Phosphatases, Non-Receptor; Receptors, N-Methyl-D-Aspartate; Synapses | 2012 |
Involvement of Tyr1472 phosphorylation of NMDA receptor NR2B subunit in postherpetic neuralgia in model mice.
Topics: Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Gene Knock-In Techniques; Glial Cell Line-Derived Neurotrophic Factor; Herpes Simplex; Herpesvirus 1, Human; Male; Mice; Mice, Inbred C57BL; Mutant Proteins; N-Methylaspartate; Neuralgia, Postherpetic; Neurites; Neurotoxins; Phosphorylation; Phosphotyrosine; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Skin; Structure-Activity Relationship; Substance P | 2012 |
Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.
Topics: Aging; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Epinephrine; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar | 2002 |
FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.
Topics: Animals; Astrocytes; Bacterial Proteins; Basement Membrane; Blotting, Western; Calbindin 2; Calbindins; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cerebral Cortex; Cytoskeletal Proteins; Disease Models, Animal; DNA-Binding Proteins; Dura Mater; Dystroglycans; Embryo, Mammalian; Extracellular Matrix Proteins; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glial Fibrillary Acidic Protein; Heterozygote; Homeodomain Proteins; Immunohistochemistry; Infections; Intracellular Signaling Peptides and Proteins; Lamins; Membrane Glycoproteins; Mice; Mice, Knockout; Microscopy, Electron; Microtubule-Associated Proteins; Muscular Dystrophies; Mutation; Nerve Tissue Proteins; Neurons; Otx Transcription Factors; Phosphopyruvate Hydratase; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Reelin Protein; S100 Calcium Binding Protein G; Serine Endopeptidases; Silver Staining; src-Family Kinases; Staining and Labeling; Transcription Factors | 2003 |
Prion-associated increases in Src-family kinases.
Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain; Cell Line, Tumor; Densitometry; Detergents; Disease Models, Animal; Glycosylphosphatidylinositols; Humans; Immunoprecipitation; Mice; Mice, Transgenic; Mutation; Phosphorylation; Phosphotyrosine; Prion Diseases; Prions; Protein Binding; Protein Conformation; Protein Isoforms; Receptors, Transferrin; Scrapie; src-Family Kinases; Time Factors; Transfection | 2005 |
PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.
Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Molecular Structure; Mutation; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Stem Cell Factor; Survival Rate; Time Factors | 2005 |
Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Endothelium, Vascular; Immunohistochemistry; Interleukin-6; Janus Kinase 1; Muscle, Smooth, Vascular; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Signal Transduction; STAT3 Transcription Factor; Subarachnoid Hemorrhage | 2006 |
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.
Topics: Amino Acid Sequence; Animals; Benzamides; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; Disease Models, Animal; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Myeloid Progenitor Cells; Phosphotransferases; Phosphotyrosine; Piperazines; Protein Structure, Tertiary; Pyrimidines; Signal Transduction; Substrate Specificity | 2006 |
Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy.
Topics: Aged; Alzheimer Disease; Animals; Apolipoproteins E; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunologic Memory; Immunotherapy; Leukocytes, Mononuclear; Lymphocyte Count; Male; Mice; Mice, Transgenic; Phosphotyrosine | 2007 |
Src-mediated cortactin phosphorylation regulates actin localization and injurious blebbing in acinar cells.
Topics: Actins; Animals; Cell Surface Extensions; Ceruletide; Cortactin; Cytoskeleton; Disease Models, Animal; Enzyme Activation; Male; Mutant Proteins; Pancreas, Exocrine; Pancreatitis; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley | 2008 |
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Immunoglobulin G; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Muscles; Neutralization Tests; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha; Tyrosine | 1994 |
Isolation and culture of retinal microglia.
Topics: Animals; Cell Division; Cell Separation; Cells, Cultured; Disease Models, Animal; Lectins; Macrophage-1 Antigen; Microscopy, Fluorescence; Neuroglia; Phagocytosis; Phosphotyrosine; Rats; Rats, Mutant Strains; Retina; Retinal Degeneration; Tyrosine; Vimentin | 1993 |
Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats.
Topics: Adaptor Proteins, Signal Transducing; Adipocytes; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Activation; Glucose Transporter Type 4; GRB2 Adaptor Protein; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Phosphatase 1; Proteins; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction | 1998 |
Characterisation of alpha-dystrobrevin in muscle.
Topics: Agrin; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Cytoskeletal Proteins; Disease Models, Animal; Dystrophin-Associated Proteins; Fetus; Humans; Membrane Proteins; Mice; Mice, Inbred mdx; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Neuropeptides; Phosphotyrosine; Protein Isoforms; Synapses; Utrophin; Vanadates | 1998 |
Induction of autoimmunity in a transgenic model of B cell receptor peripheral tolerance: changes in coreceptors and B cell receptor-induced tyrosine-phosphoproteins.
Topics: Animals; Autoantibodies; Autoantigens; B-Lymphocytes; Disease Models, Animal; Enzyme Precursors; Graft vs Host Reaction; Immune Tolerance; Immunoglobulin D; Immunoglobulin M; Intracellular Signaling Peptides and Proteins; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphocyte Activation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muramidase; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Self Tolerance; Syk Kinase | 1999 |
The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase.
Topics: Animals; Bone Marrow Cells; Cell Line; Cell Transformation, Neoplastic; Disease Models, Animal; Enzyme Activation; Female; Fusion Proteins, bcr-abl; Interleukin-3; Leukemia, B-Cell; Leukemia, Experimental; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred BALB C; Myeloid Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Point Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Signal Transduction; src Homology Domains; Stem Cells | 2001 |
Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction | 2001 |