phosphotyrosine has been researched along with Disease Exacerbation in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, JH; Hwang, YE; Jeong, J; Kang, T; Keum, S; Kim, JW; Park, D; Park, E; Rhee, S; Yang, SJ | 1 |
| Chen, A; Cheng, ML; Hung, LM; Jiang, B; Li, Q; Li, X; Lin, D; Lin, F; Ma, H; Shih, LM; Suleman, M; Sun, D; Tang, HY; Tsau, MT; Wen, S; Xie, C; Zhang, F; Zhang, J; Zhao, W; Zhou, L | 1 |
| Deng, Y; Ding, Q; He, K; Li, H; Mu, G; Wu, L; Xu, M; Yang, D; Yu, H; Zhang, L; Zhou, J | 1 |
| Ahn, R; Cory, S; Ha, JR; Hallett, M; Hardy, WR; Im, YK; Maric, G; Park, M; Pawson, T; Sabourin, V; Siegel, PM; Ursini-Siegel, J; Zhao, H | 1 |
| Rapp, UR; Sperl, B; Ulaganathan, VK; Ullrich, A | 1 |
| de la Cueva, A; Kirsch, KH; Kumbrink, J; Sailer, N; Soni, S | 1 |
| Basu, N; Bhandari, R; Natarajan, VT; Visweswariah, SS | 1 |
| Freydin, B; Hooke, JA; Hyslop, T; Klimowicz, AC; Kovatich, AJ; Liu, C; Magliocco, AM; Nevalainen, MT; Peck, AR; Pequignot, E; Rimm, DL; Rosenberg, AL; Rui, H; Sauter, G; Shriver, CD; Stringer, GA; Tran, TH; Witkiewicz, AK; Yang, N | 1 |
| Bergin, O; Dervan, PA; Easty, DJ; Fallowfield, ME; McArdle, L | 1 |
| Kulkarni, S; Levitsky, P; Malovani, H; Nir, U; Parris, W; Pawson, T; Perry, E; Pomp, O; Shpungin, S; Taller, M; Tsruya, R; Weisberg, S | 1 |
| Attems, J; Czerwenka, K; Gschwantler-Kaulich, D; Hoschützky, H; Huber, I; Hudelist, G; Köstler, WJ; Kubista, E; Manavi, M; Müller, R; Singer, CF; Zielinski, CC | 1 |
| Buchanan, FG; DuBois, RN; Gorden, DL; Matrisian, LM; Matta, P; Shi, Q | 1 |
| Earp, HS; Liu, Y; Mahajan, NP; Majumder, S; Mohler, JL; Parker, CE; Warren, MR; Whang, YE | 1 |
| Chen, CS; Chen, Y; Choong, LY; Druker, BJ; Hande, MP; Lim, S; Lim, YP; Loh, MC; Man, X; Pan, M; Poonepalli, A; Salto-Tellez, M; Shah, N; Tan, PH; Toy, W; Wong, CY | 1 |
| McKeehan, K; McKeehan, WL; Wang, F; Yu, C | 1 |
| Bolay, H; Can, A; Dalkara, T; Gürsoy-Ozdemir, Y; Onur, R; Sara, Y | 1 |
1 trial(s) available for phosphotyrosine and Disease Exacerbation
| Article | Year |
|---|---|
Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Breast Neoplasms; Disease Progression; Enzyme Activation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Middle Aged; Neoplasm Metastasis; Peptides; Phosphotyrosine; Prognosis; Receptor, ErbB-2; Survival Rate; Trastuzumab | 2006 |
15 other study(ies) available for phosphotyrosine and Disease Exacerbation
| Article | Year |
|---|---|
Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics.
Topics: Amino Acid Sequence; Cell Line, Tumor; Cell Membrane; Cell Movement; Colorectal Neoplasms; Disease Progression; Dynamin II; Gene Expression Regulation, Neoplastic; Gold; HEK293 Cells; Humans; Matrix Metalloproteinase 14; Metal Nanoparticles; Neoplasm Invasiveness; Phosphorylation; Phosphotyrosine; Protein Binding; Pseudopodia; rac1 GTP-Binding Protein; Rho Guanine Nucleotide Exchange Factors; RNA, Messenger; src Homology Domains; Up-Regulation | 2021 |
c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3.
Topics: Animals; Carcinogenesis; Colonic Neoplasms; Disease Progression; Enzyme Activation; Glycolysis; HCT116 Cells; HEK293 Cells; Humans; Mice, Inbred C57BL; Mutation; Neoplasms; Phosphofructokinase-2; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Reactive Oxygen Species | 2020 |
Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13-RhoA-ROCK signaling pathway.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Polarity; Disease Progression; Focal Adhesions; Gastrins; Golgi Apparatus; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Organic Chemicals; Pancreatic Neoplasms; Paxillin; Phosphorylation; Phosphotyrosine; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors | 2018 |
The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Fibronectins; Humans; Integrin alpha5beta1; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Mutation; Neovascularization, Pathologic; Phosphotyrosine; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Shc Signaling Adaptor Proteins; Signal Transduction; Vascular Endothelial Growth Factor A | 2013 |
Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Cell Line; Cell Membrane; Disease Models, Animal; Disease Progression; Exons; Female; Gene Knock-In Techniques; Germ-Line Mutation; Humans; Lung Neoplasms; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Polymorphism, Single Nucleotide; Receptor, Fibroblast Growth Factor, Type 4; Signal Transduction; STAT3 Transcription Factor | 2015 |
A truncated phosphorylated p130Cas substrate domain is sufficient to drive breast cancer growth and metastasis formation in vivo.
Topics: Amino Acid Motifs; Animals; Breast Neoplasms; Cell Line, Tumor; Crk-Associated Substrate Protein; CSK Tyrosine-Protein Kinase; Disease Progression; Female; Genes, Reporter; Heterografts; Humans; MCF-7 Cells; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Neoplasm Metastasis; Neoplasm Proteins; Peptide Fragments; Phosphorylation; Phosphotyrosine; Protein Domains; Protein Processing, Post-Translational; Recombinant Fusion Proteins; src-Family Kinases | 2016 |
Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Disease Progression; Enzyme Activation; Guanylate Cyclase; Humans; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Enterotoxin; Receptors, Guanylate Cyclase-Coupled; Receptors, Peptide; Sequence Alignment; src-Family Kinases | 2009 |
Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cohort Studies; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Female; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Phosphorylation; Phosphotyrosine; Prognosis; Protein Processing, Post-Translational; STAT5 Transcription Factor; Survival Analysis; Treatment Failure; Tumor Suppressor Proteins; Young Adult | 2011 |
Tyrosine phosphate in melanoma progression.
Topics: Disease Progression; Humans; Immunoenzyme Techniques; Melanocytes; Melanoma; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Skin Neoplasms; Tumor Cells, Cultured | 2003 |
TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; Brain; Brain Neoplasms; Cell Line; Culture Media, Serum-Free; Cytoplasm; Disease Progression; DNA-Binding Proteins; Down-Regulation; Elongin; Golgi Apparatus; Golgi Matrix Proteins; Immunohistochemistry; Immunoprecipitation; Mice; Molecular Sequence Data; Phosphotyrosine; Plasmids; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Sequence Homology, Amino Acid; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription Factors; Transfection; Ubiquitin; Ubiquitin-Protein Ligases; Vesicular Transport Proteins | 2004 |
Role of beta-arrestin 1 in the metastatic progression of colorectal cancer.
Topics: Arrestins; beta-Arrestin 1; beta-Arrestins; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Movement; Collagen; Colorectal Neoplasms; CSK Tyrosine-Protein Kinase; Cytosol; Densitometry; Dinoprostone; Disease Progression; Drug Combinations; ErbB Receptors; Humans; Immunohistochemistry; Immunoprecipitation; Laminin; Microscopy, Fluorescence; Models, Biological; Neoplasm Metastasis; Phosphotyrosine; Protein-Tyrosine Kinases; Proteoglycans; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; src-Family Kinases; Time Factors; Transcriptional Activation | 2006 |
Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation.
Topics: Androgens; Animals; Cell Line, Tumor; Disease Progression; DNA, Neoplasm; Enhancer Elements, Genetic; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Models, Genetic; Mutation; Neuregulin-1; Phosphorylation; Phosphotyrosine; Prostatic Neoplasms; Protein Binding; Protein Transport; Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptors, Androgen; Transcription, Genetic; Transplantation, Heterologous | 2007 |
Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics.
Topics: Animals; Asian People; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Drug Delivery Systems; Drug Resistance, Neoplasm; Enzyme Activation; ErbB Receptors; Female; Gefitinib; Gene Dosage; Humans; Mice; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; Proteomics; Quinazolines; Reproducibility of Results | 2007 |
Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.
Topics: Animals; Binding Sites; Cell Division; Cellular Senescence; Disease Progression; Isoenzymes; Male; MAP Kinase Signaling System; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Precancerous Conditions; Prostatic Neoplasms; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Transcription, Genetic; Transfection; Type C Phospholipases | 2002 |
Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.
Topics: Animals; Calcium-Binding Proteins; Cerebral Cortex; Disease Progression; Glutamic Acid; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Membrane Glycoproteins; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar; Synapsins; Synaptic Transmission; Synaptophysin; Synaptotagmins; Time | 2002 |