phosphotyrosine has been researched along with Cell Transformation, Viral in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (74.77) | 18.7374 |
| 1990's | 26 (23.42) | 18.2507 |
| 2000's | 2 (1.80) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alberti, A; Chow, YH; De las Heras, M; Grego, E; Jones, L; Palmarini, M; Pretto, C; Zavala, G | 1 |
| Martinez, R; Nakamura, KD; Weber, MJ | 1 |
| Albigès-Rizo, C; Badowski, C; Block, MR; Chabadel, A; Grichine, A; Jurdic, P; Oddou, C; Pawlak, G; Pfaff, M | 1 |
| Dezelee, P; Perrot, D | 1 |
| Gilmore, T; Martin, GS; Radke, K | 1 |
| Anderson, DD; Beckmann, RP; Harms, EH; Nakamura, K; Weber, MJ | 1 |
| Blomberg, J; Reynolds, FH; Stephenson, JR; Van de Ven, WJ | 1 |
| Blomberg, J; Nalewaik, RP; Reynolds, FH; Stephenson, JR; Van de Ven, WJ | 1 |
| Chen, LB; Cheng, YS | 1 |
| Pepinsky, RB; Racker, E; Spector, M; Vogt, VM | 1 |
| Barbacid, M; Donner, L; Ruscetti, SK; Sherr, CJ | 1 |
| Sen, A | 1 |
| Kolata, GB | 1 |
| Benjamin, TL; Schaffhausen, B | 1 |
| Ghysdael, J; Neil, JC; Vogt, PK | 1 |
| Baltimore, D; Eisen, HN; Ross, AH | 1 |
| Erikson, RL; Gilmer, TM | 1 |
| Cooper, JA; Hunter, T | 2 |
| Marquardt, H; Reynolds, FH; Stephenson, JR; Todaro, GJ; Twardzik, DR | 1 |
| Balduzzi, PC; Feldman, RA; Hanafusa, H; Wang, LH | 1 |
| Kahn, P; Nakamura, K; Shin, S; Smith, RE; Weber, MJ | 1 |
| Beemon, K; McNelly, EA; Ryden, T | 1 |
| Berdot, C; Elliott, T; Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Benjamin, TL; Carmichael, GG; Dorsky, DI; Oliver, DB; Schaffhausen, BS | 1 |
| Adkins, B; Hunter, T; Sefton, BM | 1 |
| Ito, S; Pastan, I; Richert, N | 1 |
| Blomberg, J; Oroszlan, S; Reynolds, FH; Stephenson, JR | 1 |
| Fedele, LA; Galibert, F; Hampe, A; Laprevotte, I; Sherr, CJ | 1 |
| Ponticelli, AS; Rosenberg, N; Whitlock, CA; Witte, ON | 1 |
| Albert, D; Chen, AP; de Noronha, F; Essex, M; Kelliher, M; Niederkorn, JY; Shadduck, JA | 1 |
| Cooper, J; Hunter, T; Nakamura, KD; Weber, MJ | 1 |
| Hirano, A; Neil, JC; Vogt, PK | 1 |
| Iwashita, S; Kitamura, N; Yoshida, M | 1 |
| Garber, EA; Goldberg, AR; Hanafusa, H; Krueger, JG | 1 |
| Rohrschneider, L; Rosok, MJ | 1 |
| Blat, C; Golde, A; Harel, L; Villaudy, J | 1 |
| Pawson, T; Weinmaster, G | 1 |
| Brugge, JS; Darrow, D; Lipsich, LA; Yonemoto, W | 1 |
| Erikson, E; Erikson, RL; Foulkes, JG; Gilmer, TM | 1 |
| Baltimore, D; Foulkes, JG; Prywes, R; Rosenberg, N | 1 |
| Eisen, HN; Frackelton, AR; Ross, AH | 1 |
| Biquard, JM; Krsmanovic, V; Lee, SY; Paire, J; Vernet, G | 1 |
| Foulkes, JG | 1 |
| Comoglio, PM; Di Renzo, MF; Giancotti, FG; Marchisio, PC; Naldini, L; Tarone, G | 1 |
| Erikson, RL | 1 |
| Konopka, JB; Watanabe, SM; Witte, ON | 1 |
| Brown, DJ; Gordon, JA | 1 |
| Clinton, GM; Finley-Whelan, J | 1 |
| Hunter, T | 1 |
| Bauer, H; Ferdinand, FJ; Friis, RR; Gardner, L; Hennig, D; Johnson, L; Pedersen, NC; Theilen, GH; Ziemiecki, A | 1 |
| Cirillo, D; Comoglio, PM; Marchisio, PC; Naldini, L | 1 |
| Fujita, DJ; Vogel, LB | 1 |
| Hayman, MJ; Morimoto, AM | 1 |
| Nakamura, N; Sobue, K; Tanaka, J | 1 |
| Johansson, MW; Larsson, E; Lüning, B; Pasquale, EB; Ruoslahti, E | 1 |
| Huang, TS; Kuo, ML; Lin, JK; Yang, NC | 1 |
| Jelinek, T; Kaleko, M; Peterson, JE; Siddle, K; Weber, MJ | 1 |
| Cool, DE; Diltz, CD; Fischer, EH; Krebs, EG; Rohrschneider, LR; Zander, NF | 1 |
| Akiho, H; Noda, M; Nomura, Y; Tokumitsu, Y | 1 |
| Biesinger, B; Bröker, BM; Chitaev, NA; Emmrich, F; Fleckenstein, B; Guse, AH; Müller-Fleckenstein, I; Tsygankov, AY | 1 |
| Birge, RB; Cantley, LC; Fajardo, JE; Hanafusa, H; Reichman, C; Shoelson, SE; Songyang, Z | 1 |
| Andersson, LC; Auvinen, M; Hölttä, E | 1 |
| Bell, SM; Connolly, DC; Degen, JL; Maihle, NJ | 1 |
| Aguzzi, A; Brugge, JS; Soriano, P; Thomas, JE; Wagner, EF | 1 |
| Kuzumaki, N; Ogiso, Y; Shih, TY; Watari, H; Yokoyama, T | 1 |
| Frech, B; Fruehling, S; Grässer, FA; Herrold, R; Kremmer, E; Laux, G; Lee, SK; Longnecker, R | 1 |
| Birge, RB; Greulich, H; Hanafusa, H; Nievers, MG; van Bergen en Henegouwen, PM; Verkleij, AJ | 1 |
| Amrein, KE; Hurley, TR; Sefton, BM | 1 |
| Baltimore, D; Jackson, PK; Mayer, BJ; Van Etten, RA | 1 |
| Dixon, JE; Rhodes, JD; Woodford-Thomas, TA | 1 |
| Guan, JL; Shalloway, D | 1 |
| Carpenter, CL; Hou, W; Kapeller, R; Liu, Y; Schaffhausen, BS; Yoakim, M | 1 |
| Fukui, Y; Hanafusa, H; Matsuda, M; Mayer, BJ | 1 |
| Eason, P; Hirst, EM; Kellie, S; Nermut, MV | 1 |
| Cheung, RK; Dosch, HM | 1 |
| Druker, B; Kieff, E; Longnecker, R; Roberts, TM | 1 |
| Hanafusa, H | 1 |
| Klarlund, JK | 1 |
| Courtneidge, SA | 1 |
| Cirillo, D; Comoglio, PM; Giancotti, FG; Marchisio, PC; Tarone, G | 1 |
| Fujio, H; Owada, MK; Sakato, N; Seki, J | 1 |
| Brugge, JS | 1 |
| Sefton, BM | 1 |
| Lau, AF | 1 |
| Hunter, T; Patschinsky, T; Sefton, BM | 1 |
| Fukami, Y; Kanehisa, T; Nakamura, T; Nakayama, A | 1 |
| Martegani, E; Sturani, E; Toschi, L; Zippel, R | 1 |
| Cartwright, CA; Eckhart, W; Hutchinson, MA | 1 |
| Maher, PA; Pasquale, EB; Singer, SJ | 1 |
| Cooper, JA; King, CS; Moss, B; Twardzik, DR | 1 |
| Brugge, JS; Filson, AJ; Queral-Lustig, AE; Wang, JY; Yonemoto, W | 1 |
| Ogawa, R; Sugamura, K; Watanabe, Y | 1 |
| Belzer, SK; Collett, MS | 1 |
| Huang, ES; Muganda-Ojiaku, PM | 1 |
| Cantley, L; Kaplan, DR; Pallas, DC; Roberts, TM; Schaffhausen, B; White, M; Whitman, M | 1 |
| Burr, JG; Linder, ME | 2 |
| Kamps, MP; Sefton, BM | 2 |
| Kawai, S; Mizuno, S; Murakami, Y; Uehara, Y | 1 |
| Hunter, T; Middlemas, DS; Weinmaster, GA | 1 |
| Comoglio, PM; D'Urso, N; Giancotti, FG; Marchisio, PC; Tarone, G | 1 |
| Kaplan, JM; Varmus, HE; Verderame, MF | 1 |
| Eigenbrodt, E; Presek, P; Reinacher, M | 1 |
| Kato, J; Sato, M; Takeya, T | 1 |
| Grandori, C; Hamaguchi, M; Hanafusa, H | 1 |
| Buck, C; Duggan, K; Horwitz, A; Rohrschneider, L; Tapley, P | 1 |
| Glenney, JR; Zokas, L | 1 |
| Gavazzi, I; Marchisio, PC; Nermut, MV | 1 |
| Antler, AM; Edelman, GM; Greenberg, ME; Hanafusa, H | 1 |
2 review(s) available for phosphotyrosine and Cell Transformation, Viral
| Article | Year |
|---|---|
Phosphotyrosyl-protein phosphatases.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cell Transformation, Viral; Oncogenes; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Retroviridae; Tyrosine | 1983 |
Protein phosphorylation and cell transformation.
Topics: 1-Phosphatidylinositol 4-Kinase; Cell Transformation, Neoplastic; Cell Transformation, Viral; Genes, src; Humans; Neoplasm Proteins; Oncogene Protein pp60(v-src); Oncogene Protein v-crk; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein Binding; Retroviridae Proteins, Oncogenic; Signal Transduction; Tyrosine | 1991 |
109 other study(ies) available for phosphotyrosine and Cell Transformation, Viral
| Article | Year |
|---|---|
Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus.
Topics: Animals; Cell Size; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Chickens; Fibroblasts; Jaagsiekte sheep retrovirus; Lung; Lung Neoplasms; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Adenomatosis, Ovine; Sheep, Domestic; Tumor Cells, Cultured; Viral Envelope Proteins | 2003 |
Identification of phosphotyrosine-containing proteins in untransformed and Rous sarcoma virus-transformed chicken embryo fibroblasts.
Topics: Animals; Avian Leukosis Virus; Cell Transformation, Viral; Chick Embryo; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Molecular Weight; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Proteins | 1982 |
Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization.
Topics: Animals; Calpain; Cell Communication; Cell Movement; Cell Transformation, Viral; Cricetinae; Enzyme Activation; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Mice; Mutant Proteins; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Pseudopodia; Rous sarcoma virus; Vanadates | 2008 |
Modifications in the phosphorylation of cell proteins related to the expression of src gene in chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Gene Expression Regulation; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Tyrosine; Viral Proteins | 1984 |
Transformation by Rous sarcoma virus: a cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Tyrosine; Viral Proteins | 1980 |
Biological properties of "partial" transformation mutants of Rous sarcoma virus and characterization of their pp60src kinase.
Topics: Animals; Avian Sarcoma Viruses; Cell Adhesion; Cell Division; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeleton; Fibronectins; Fluorescent Antibody Technique; Microscopy, Electron, Scanning; Mutation; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1981 |
Differences in mechanisms of transformation by independent feline sarcoma virus isolates.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Epidermal Growth Factor; Mink; Phosphotyrosine; Protein Kinases; Rats; Retroviridae; Sarcoma Viruses, Feline; Tyrosine; Viral Proteins | 1981 |
Snyder-Theilen feline sarcoma virus P85 contains a single phosphotyrosine acceptor site recognized by its associated protein kinase.
Topics: Binding Sites; Cell Transformation, Neoplastic; Cell Transformation, Viral; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae; Sarcoma Viruses, Feline; Serine; Tyrosine; Viral Proteins | 1981 |
Detection of phosphotyrosine-containing 34,000-dalton protein in the framework of cells transformed with Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Cytoplasm; Fibronectins; Interferons; Molecular Weight; Phosphorylation; Phosphotyrosine; Proteins; Rats; Temperature; Tyrosine | 1981 |
A mouse homolog to the avian sarcoma virus src protein is a member of a protein kinase cascade.
Topics: Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Transformation, Viral; Mice; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein Kinases; Rats; Tyrosine; Viral Proteins | 1981 |
Transformation-defective mutants of Snyder-Theilen feline sarcoma virus lack tyrosine-specific protein kinase activity.
Topics: Animals; Cell Line; Cell Transformation, Viral; Genes, Viral; Mink; Mutation; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae; Sarcoma Viruses, Feline; Tyrosine; Viral Proteins | 1981 |
Purified low-molecular-weight protein kinase from murine sarcoma virus particles catalyzes tyrosine phosphorylation endogenously but phosphorylates cellular proteins at serine.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Viral; Magnesium; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Sarcoma Viruses, Murine; Serine; Tyrosine | 1981 |
Reevaluation of cancer data eagerly awaited.
Topics: Biomedical Research; Cell Transformation, Viral; Glycolysis; Neoplasms, Experimental; Phosphotyrosine; Protein Kinases; Sodium-Potassium-Exchanging ATPase; Tyrosine | 1981 |
Comparison of phosphorylation of two polyoma virus middle T antigens in vivo and in vitro.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Antigens, Viral, Tumor; Cell Line; Cell Transformation, Viral; Cell-Free System; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Polyomavirus; Protein Kinases; Tyrosine | 1981 |
Cleavage of four avian sarcoma virus polyproteins with virion protease p15 removes gag sequences and yields large fragments that function as tyrosine phosphoacceptors in vitro.
Topics: Alpharetrovirus; Cell Transformation, Viral; Gene Products, gag; Peptide Fragments; Peptide Hydrolases; Phosphoproteins; Phosphotyrosine; Protein Kinases; Structure-Activity Relationship; Tyrosine; Viral Proteins | 1981 |
Phosphotyrosine-containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten.
Topics: Antibody Specificity; Cell Transformation, Viral; Chromatography, Affinity; Haptens; Phosphotyrosine; Proteins; Tyrosine | 1981 |
Rous sarcoma virus transforming protein, p60src, expressed in E. coli, functions as a protein kinase.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; DNA, Recombinant; Escherichia coli; Genes, Viral; Phosphoproteins; Phosphotyrosine; Protein Kinases; Tyrosine | 1981 |
Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.
Topics: Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Receptors, Cell Surface; Tyrosine | 1981 |
Transformation induced by Abelson murine leukemia virus involves production of a polypeptide growth factor.
Topics: Abelson murine leukemia virus; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; ErbB Receptors; Molecular Weight; Peptides; Phosphotyrosine; Rats; Receptors, Cell Surface; Transforming Growth Factors; Tyrosine | 1982 |
Avian sarcoma virus UR2 encodes a transforming protein which is associated with a unique protein kinase activity.
Topics: Alpharetrovirus; Animals; Cell Transformation, Viral; Chick Embryo; Genes, Viral; Phosphorylation; Phosphotyrosine; RNA, Viral; Tyrosine; Viral Proteins | 1982 |
Tumorigenicity of partial transformation mutants of Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Body Temperature; Cell Transformation, Viral; Chick Embryo; Chickens; Graft Rejection; Mice; Mice, Nude; Neoplasm Transplantation; Phosphotyrosine; Sarcoma, Avian; Species Specificity; Tyrosine; Virulence | 1982 |
Transformation by avian sarcoma viruses leads to phosphorylation of multiple cellular proteins on tyrosine residues.
Topics: Alpharetrovirus; Animals; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Fibroblasts; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Proteins; Tyrosine; Viral Proteins | 1982 |
Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1982 |
Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation.
Topics: Animals; Antigens, Viral; Antigens, Viral, Tumor; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Cytoplasm; DNA, Recombinant; Mice; Mutation; Phosphotyrosine; Polyomavirus; Protein Kinases; Structure-Activity Relationship; Tyrosine | 1982 |
Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Compartmentation; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeleton; Detergents; Phosphoproteins; Phosphotyrosine; Protein Kinases; Solubility; Tyrosine | 1982 |
The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins.
Topics: Alpharetrovirus; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chick Embryo; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1982 |
Phospholipids stimulate phosphorylation of vinculin by the tyrosine-specific protein kinase of Rous sarcoma virus.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Enzyme Activation; Magnesium; Manganese; Muscle Proteins; Phosphatidylinositols; Phospholipids; Phosphorylation; Phosphotyrosine; Protein Kinases; Substrate Specificity; Tyrosine; Vinculin | 1982 |
Tyrosine phosphorylation sites common to transforming proteins encoded by Gardner and Snyder-Theilen FeSV.
Topics: Animals; Cell Line; Cell Transformation, Viral; Molecular Weight; Peptide Fragments; Phosphorylation; Phosphotyrosine; Protein Precursors; Protein Processing, Post-Translational; Rats; Retroviridae; Sarcoma Viruses, Feline; Tyrosine; Viral Proteins | 1982 |
Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes.
Topics: Amino Acid Sequence; Base Sequence; Biological Evolution; Cell Transformation, Viral; Gene Products, gag; Genes; Genes, Viral; Oncogenes; Phosphotyrosine; Protein Kinases; Retroviridae; Sarcoma Viruses, Feline; Substrate Specificity; Tyrosine; Viral Proteins | 1982 |
In vivo tyrosine phosphorylations of the Abelson virus transforming protein are absent in its normal cellular homolog.
Topics: Abelson murine leukemia virus; Animals; Cell Transformation, Viral; Cross Reactions; Leukemia Virus, Murine; Mice; Oncogenes; Phosphorylation; Phosphotyrosine; Tyrosine | 1982 |
Feline sarcoma virus-specific transformation-related proteins and protein kinase activity in tumor cells.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Fibrosarcoma; Gene Products, gag; Melanoma; Mink; Peptides; Phosphotyrosine; Protein Kinases; Retroviridae; Retroviridae Proteins, Oncogenic; Sarcoma Viruses, Feline; Tumor Virus Infections; Tyrosine; Viral Proteins | 1983 |
Phosphotyrosine-containing proteins and expression of transformation parameters in cells infected with partial transformation mutants of Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Genetic Markers; Mutation; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Species Specificity; Tyrosine; Viral Proteins | 1983 |
ts Transformation mutants of avian sarcoma virus PRCII: lack of strict correlation between transforming ability and properties of the P105-associated kinase.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Fibroblasts; Helper Viruses; Mutation; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein Kinases; Temperature; Tyrosine; Viral Proteins | 1983 |
Molecular events leading to fusiform morphological transformation by partial src deletion mutant of Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Fibronectins; Muscle Proteins; Mutation; Phosphoproteins; Phosphotyrosine; Tyrosine; Vinculin | 1983 |
Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins.
Topics: Animals; Avian Sarcoma Viruses; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Membrane Proteins; Mutation; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein Kinases; Temperature; Tyrosine; Viral Proteins | 1983 |
Transformation parameters and pp60src localization in cells infected with partial transformation mutants of Rous sarcoma virus.
Topics: Animals; Cell Adhesion; Cell Compartmentation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chickens; Contractile Proteins; Cytoskeleton; Fibronectins; Filamins; Microfilament Proteins; Muscle Proteins; Mutation; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphotyrosine; Tyrosine; Vinculin; Viral Proteins | 1983 |
Rous sarcoma virus-induced changes in the pattern of phosphorylation of non-histone nuclear proteins.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Chromosomal Proteins, Non-Histone; Fibroblasts; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Kinases; Tyrosine | 1983 |
Localization and characterization of phosphorylation sites of the Fujinami avian sarcoma virus and PRCII virus transforming proteins.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Gene Products, gag; Phosphorylation; Phosphotyrosine; Tyrosine; Viral Proteins | 1982 |
The association of the transforming protein of Rous sarcoma virus with two cellular phosphoproteins.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chickens; Macromolecular Substances; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1983 |
Avian sarcoma viruses, protein kinases and cell transformation.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Epidermal Growth Factor; Escherichia coli; Gene Expression Regulation; Oncogene Protein pp60(v-src); Phosphoprotein Phosphatases; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1983 |
Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation.
Topics: Abelson murine leukemia virus; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Viral; Fibroblasts; Leukemia Virus, Murine; Lymphocytes; Mice; Molecular Weight; Peptides; Phosphotyrosine; Transforming Growth Factors; Tyrosine | 1983 |
Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Transformation, Viral; Cells, Cultured; Epidermal Growth Factor; Humans; Mice; Phosphoproteins; Phosphotyrosine; Protein Kinases; Tyrosine | 1983 |
Immunological study of a cellular 35K phosphorylated polypeptide detected in Rous sarcoma virus transformed cells.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Coturnix; Cricetinae; Cytoskeleton; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Kinases; Rats; Tyrosine; Viral Proteins | 1983 |
Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies.
Topics: Animals; Avian Sarcoma Viruses; Azo Compounds; Cell Transformation, Viral; Fluorescent Antibody Technique; Molecular Weight; Muscle Proteins; Oncogene Protein pp60(v-src); p-Azobenzenearsonate; Phosphoproteins; Phosphotyrosine; Tyrosine; Vinculin; Viral Proteins | 1984 |
Functional studies on the Rous sarcoma virus transforming gene product.
Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Viral Proteins | 1984 |
An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.
Topics: Animals; Cell Transformation, Viral; DNA, Neoplasm; Gene Expression Regulation; Humans; Leukemia, Experimental; Neoplasm Proteins; Oncogenes; Peptide Fragments; Phosphoproteins; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine | 1984 |
The stimulation of pp60v-src kinase activity by vanadate in intact cells accompanies a new phosphorylation state of the enzyme.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Immunoglobulin Heavy Chains; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein Kinases; Tyrosine; Vanadium; Viral Proteins | 1984 |
Tyrosyl kinases acquired from anchorage-independent cells by a membrane-enveloped virus.
Topics: Amino Acids; Animals; Cell Adhesion; Cell Line; Cell Transformation, Viral; Cricetinae; Kidney; Kinetics; Phosphorus Radioisotopes; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine; Vesicular stomatitis Indiana virus; Virion | 1984 |
The proteins of oncogenes.
Topics: Animals; Annexins; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA; Epidermal Growth Factor; ErbB Receptors; Guanosine Triphosphate; Humans; Membrane Proteins; Neoplasm Proteins; Nucleoproteins; Oncogene Protein pp60(v-src); Oncogenes; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Binding; Protein Biosynthesis; Protein Kinases; Receptors, Cell Surface; Retroviridae; Tyrosine; Viral Proteins | 1984 |
Biological and biochemical characterization of a new isolate of feline sarcoma virus: Theilen-Pedersen (TP1-FeSV).
Topics: Acylation; Animals; Cats; Cell Transformation, Viral; Cells, Cultured; Gene Products, gag; Oncogenes; Phosphotyrosine; Protein Kinases; Retroviridae; Sarcoma Viruses, Feline; Tyrosine; Viral Proteins; Virus Replication | 1984 |
Visualization of phosphotyrosine containing molecules within the detergent insoluble cell matrix of v-src transformed fibroblasts.
Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Detergents; Gold; Immunoenzyme Techniques; Mice; Mice, Inbred Strains; Oncogene Protein pp60(v-src); Phosphotyrosine; Tyrosine; Viral Proteins | 1984 |
The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Binding Sites; Cell Line; Cell Transformation, Viral; Chick Embryo; Humans; In Vitro Techniques; Leukocytes; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; T-Lymphocytes; Tyrosine | 1993 |
Role of oligomerization of the S13 Env-Sea oncoprotein in cell transformation.
Topics: Alpharetrovirus; Animals; Blotting, Western; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Centrifugation, Density Gradient; Glycoproteins; Hexosaminidases; Oncogene Proteins, Viral; Oxidation-Reduction; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein-Tyrosine Kinases; Rats; Tyrosine | 1994 |
Rous sarcoma virus-transformed cells develop peculiar adhesive structures along the cell periphery.
Topics: Actins; Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Cell Adhesion; Cell Membrane; Cell Transformation, Viral; Cytoplasm; Fluorescent Antibody Technique; Integrins; Microscopy, Electron, Scanning Transmission; Molecular Sequence Data; Phosphoproteins; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Rats; Receptors, Cytoadhesin; Receptors, Fibronectin; Receptors, Vitronectin; Time Factors; Tyrosine | 1993 |
Altered localization and cytoplasmic domain-binding properties of tyrosine-phosphorylated beta 1 integrin.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Cell Adhesion; Cell Compartmentation; Cell Membrane; Cell Transformation, Viral; Integrin beta1; Integrins; Mice; Molecular Sequence Data; Peptides; Phosphotyrosine; Tyrosine | 1994 |
Reversion of the transformed phenotypes of v-H-ras NIH3T3 cells by flavonoids through attenuating the content of phosphotyrosine.
Topics: 3T3 Cells; Animals; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chamomile; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Flavonoids; Genes, ras; Genistein; Isoflavones; Kaempferols; Mice; Oils, Volatile; Phenotype; Phosphotyrosine; Plants, Medicinal; Protein-Tyrosine Kinases; Quercetin; Tyrosine | 1994 |
c phosphorylation and activation of the IGF-I receptor in src-transformed cells.
Topics: Animals; Cell Line; Cell Transformation, Viral; Genes, src; Humans; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Rats; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Time Factors; Transfection; Tyrosine | 1994 |
Suppression of v-fms-induced transformation by overexpression of a truncated T-cell protein tyrosine phosphatase.
Topics: Animals; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Genes, fms; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; T-Lymphocytes; Transfection; Tyrosine | 1993 |
Decrease in coupling of Gs in v-src-transformed NIH-3T3 fibroblasts: possible involvement of tyrosine phosphorylation of Gs by pp60v-src.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Cell Transformation, Viral; Cyclic AMP; Genes, src; GTP-Binding Proteins; In Vitro Techniques; Iodocyanopindolol; Membrane Proteins; Mice; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Phosphotyrosine; Pindolol; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Signal Transduction; Tyrosine | 1993 |
Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors.
Topics: Antigens, Bacterial; Calcium; Cell Division; Cell Transformation, Viral; Clone Cells; Herpesvirus 2, Saimiriine; Humans; In Vitro Techniques; Phosphoproteins; Phosphotyrosine; T-Lymphocytes; Tetanus Toxoid; Tyrosine | 1993 |
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Oncogene Protein v-crk; Oncogenes; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Binding; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Tyrosine; Vanadates | 1993 |
Polyamines are essential for cell transformation by pp60v-src: delineation of molecular events relevant for the transformed phenotype.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Line; Cell Transformation, Viral; Eflornithine; GTPase-Activating Proteins; Oncogene Protein pp60(v-src); Ornithine Decarboxylase; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Polyamines; Proteins; ras GTPase-Activating Proteins; Rats; Signal Transduction; Tyrosine | 1993 |
Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases.
Topics: Animals; Cell Transformation, Viral; Chick Embryo; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyrosine; Urokinase-Type Plasminogen Activator | 1993 |
Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src.
Topics: Animals; Antigens, Polyomavirus Transforming; Cell Transformation, Viral; Cells, Cultured; Gene Expression Regulation, Viral; In Vitro Techniques; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); src-Family Kinases; Tyrosine | 1993 |
Resistance of NIH3T3 cells to v-fes transformation induced by a dominant negative H-ras mutant.
Topics: 3T3 Cells; Animals; Cell Transformation, Viral; Fusion Proteins, gag-onc; Gene Expression Regulation, Viral; Genes, Dominant; Genes, ras; Mice; Oncogene Proteins, Viral; Oncogenes; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Tyrosine | 1993 |
Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; B-Lymphocytes; Base Sequence; Calcium; Cell Line, Transformed; Cell Transformation, Viral; DNA Primers; DNA, Viral; Fluorescent Antibody Technique; Genetic Vectors; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Mutagenesis; Oncogene Proteins, Viral; Phosphotyrosine; Polymerase Chain Reaction; Protein Structure, Secondary; Rats; Receptors, Antigen, B-Cell; Recombination, Genetic; Sequence Deletion; Signal Transduction; Viral Matrix Proteins; Virus Replication | 1996 |
v-Crk-induced cell transformation: changes in focal adhesion composition and signaling.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Crk-Associated Substrate Protein; Cytoskeleton; Mice; Oncogene Protein v-crk; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Retroviridae Proteins, Oncogenic; Signal Transduction; src Homology Domains | 1997 |
Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Base Sequence; Cell Transformation, Viral; Cells, Cultured; Enzyme Stability; Escherichia coli; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oncogene Proteins, Viral; Oncogenes; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Sequence Homology, Amino Acid; Temperature; Thermodynamics; Tyrosine | 1992 |
Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cloning, Molecular; DNA Mutational Analysis; Humans; Immunoblotting; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oncogene Proteins v-abl; Phosphotyrosine; Retroviridae; Tyrosine | 1992 |
Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Endoplasmic Reticulum; Gene Expression; Mice; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phosphotyrosine; Protein Tyrosine Phosphatases; Transfection; Tyrosine | 1992 |
Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Line; Cell Transformation, Viral; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunologic Techniques; In Vitro Techniques; Integrins; Membrane Glycoproteins; Mice; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1992 |
Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase.
Topics: 1-Phosphatidylinositol 4-Kinase; 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Binding Sites; Cell Transformation, Viral; Cloning, Molecular; Genes, src; Mice; Models, Biological; Phosphoproteins; Phosphotransferases; Phosphotyrosine; Polyomavirus; Protein Conformation; Tyrosine | 1992 |
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins.
Topics: Animals; Cell Line, Transformed; Cell Transformation, Viral; Oncogene Protein v-crk; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Retroviridae Proteins; Signal Transduction; Tyrosine | 1990 |
Cell/substratum adhesions in RSV-transformed rat fibroblasts.
Topics: Actin Cytoskeleton; Actinin; Actins; Animals; Avian Sarcoma Viruses; Cell Adhesion; Cell Transformation, Viral; Clathrin; Cytoskeletal Proteins; Fluorescent Antibody Technique; In Vitro Techniques; Intermediate Filaments; Microscopy, Electron, Scanning; Oncogene Protein pp60(v-src); Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Tyrosine; Vinculin | 1991 |
The tyrosine kinase lck is critically involved in the growth transformation of human B lymphocytes.
Topics: B-Lymphocytes; Base Sequence; Blotting, Western; Cell Transformation, Viral; Gene Expression; Herpesvirus 4, Human; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Oligonucleotide Probes; Oligonucleotides, Antisense; Phosphotyrosine; Protein-Tyrosine Kinases; Time Factors; Tyrosine | 1991 |
An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase.
Topics: Amino Acid Sequence; Antigens, Viral; Cell Line; Cell Transformation, Viral; Cloning, Molecular; DNA Mutational Analysis; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; In Vitro Techniques; Membrane Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Structure-Activity Relationship; Transfection; Tyrosine; Viral Matrix Proteins; Viral Proteins | 1991 |
Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Deoxyglucose; Kinetics; Mice; Moloney murine sarcoma virus; Phosphatidylinositols; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphotyrosine; Rats; Tyrosine; Vanadates; Vanadium; Zinc | 1985 |
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Transformation, Viral; Enzyme Activation; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); Rats; Tyrosine; Vanadates; Vanadium; Viral Proteins | 1985 |
Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes.
Topics: Actins; Animals; Avian Sarcoma Viruses; Cell Adhesion; Cell Transformation, Viral; Cricetinae; Cytoskeletal Proteins; Fibroblasts; Microscopy, Electron; Muscle Proteins; Phosphotyrosine; Tyrosine; Vinculin | 1985 |
Direct identification of phosphotyrosine-containing proteins in some retrovirus-transformed cells by use of anti-phosphotyrosine antibody.
Topics: Animals; Antibodies; Antibody Specificity; B-Lymphocytes; Cell Transformation, Viral; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae; Tyrosine | 1986 |
Interaction of the Rous sarcoma virus protein pp60src with the cellular proteins pp50 and pp90.
Topics: Animals; Avian Sarcoma Viruses; Binding Sites; Biological Transport; Cell Membrane; Cell Transformation, Viral; Macromolecular Substances; Molecular Weight; Mutation; Myristates; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine | 1986 |
The viral tyrosine protein kinases.
Topics: Abelson murine leukemia virus; Animals; Avian Sarcoma Viruses; Cell Compartmentation; Cell Transformation, Viral; ErbB Receptors; Myristic Acid; Myristic Acids; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Cell Surface; Retroviridae; Retroviridae Proteins; Substrate Specificity; Tyrosine | 1986 |
Phosphotyrosine-containing 120,000-dalton protein coimmunoprecipitated with pp60v-src from Rous sarcoma virus-transformed mammalian cells.
Topics: Animals; Arvicolinae; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chemical Precipitation; Chick Embryo; Epitopes; Immune Sera; Mice; Molecular Weight; Muscle Proteins; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Retroviridae Proteins; Tyrosine; Vinculin | 1986 |
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chickens; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Retroviridae Proteins; Species Specificity; Tyrosine; Vanadium | 1986 |
Phosphorylation of tyrosine residues of calmodulin in Rous sarcoma virus-transformed cells.
Topics: Animals; Avian Sarcoma Viruses; Calmodulin; Cell Transformation, Viral; Chick Embryo; In Vitro Techniques; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine | 1986 |
The interaction with PDGF as a source of G1 phase heterogeneity in normal mouse fibroblasts.
Topics: Animals; Cell Cycle; Cell Transformation, Viral; Culture Media; Fibroblasts; Interphase; Mice; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Simian virus 40; Tyrosine | 1986 |
Structural and functional modification of pp60c-src associated with polyoma middle tumor antigen from infected or transformed cells.
Topics: Amino Acid Sequence; Animals; Antigens, Viral, Tumor; Cell Line; Cell Transformation, Viral; Mice; Peptide Fragments; Phosphorylation; Phosphotyrosine; Polyomavirus; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Rats; Tyrosine | 1985 |
Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; Immunologic Techniques; Muscle Proteins; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Talin; Tyrosine; Vinculin | 1986 |
Vaccinia virus growth factor stimulates tyrosine protein kinase activity of A431 cell epidermal growth factor receptors.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Viral; Enzyme Activation; ErbB Receptors; Growth Substances; Humans; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vaccinia virus; Viral Proteins | 1986 |
Detection of phosphotyrosine-containing proteins in polyomavirus middle tumor antigen-transformed cells after treatment with a phosphotyrosine phosphatase inhibitor.
Topics: Antigens, Viral, Tumor; Cell Transformation, Viral; Immunosorbent Techniques; Molecular Weight; Phosphoprotein Phosphatases; Phosphoproteins; Phosphotyrosine; Polyomavirus; Protein Tyrosine Phosphatases; Tyrosine; Vanadium | 1987 |
Tyrosine phosphorylation of an interleukin 2 receptor-like protein in cells transformed by human T cell leukemia virus type I.
Topics: Antibodies, Monoclonal; Cell Line; Cell Transformation, Viral; Deltaretrovirus; Humans; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tyrosine | 1987 |
Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.
Topics: Animals; Antibodies, Monoclonal; Arvicolinae; Avian Sarcoma Viruses; Cell Transformation, Viral; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadium | 1987 |
Alteration of protein phosphorylation patterns in cell lines morphologically transformed by human cytomegalovirus.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Humans; Isoelectric Point; Membrane Proteins; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Kinases; Spermidine; Tyrosine | 1987 |
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Gene Expression Regulation; Mice; Mice, Inbred BALB C; Oncogene Protein gp140(v-fms); Oncogene Proteins v-sis; Oncogene Proteins, Viral; Oncogenes; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Platelet-Derived Growth Factor; Polyomavirus; Protein-Tyrosine Kinases; Retroviridae Proteins; Simian virus 40; Substrate Specificity; Tyrosine | 1987 |
Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Immunosorbent Techniques; Membrane Proteins; Molecular Weight; Myristic Acid; Myristic Acids; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Retroviridae Proteins; Structure-Activity Relationship; Subcellular Fractions; Tyrosine | 1988 |
Identification of multiple novel polypeptide substrates of the v-src, v-yes, v-fps, v-ros, and v-erb-B oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine.
Topics: Animals; Antibodies; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Oncogene Proteins, Viral; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Substrate Specificity; Tyrosine | 1988 |
Inhibition of transforming activity of tyrosine kinase oncogenes by herbimycin A.
Topics: Animals; Arvicolinae; Benzoquinones; Cell Line; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Lactams, Macrocyclic; Mice; Oncogene Proteins, Viral; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tyrosine | 1988 |
A major site of tyrosine phosphorylation within the SH2 domain of Fujinami sarcoma virus P130gag-fps is not required for protein-tyrosine kinase activity or transforming potential.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; DNA Mutational Analysis; Gene Expression Regulation; Oncogene Proteins, Viral; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Structure-Activity Relationship; Tyrosine; Viral Fusion Proteins | 1988 |
Immunological characterization of proteins detected by phosphotyrosine antibodies in cells transformed by Rous sarcoma virus.
Topics: Annexins; Avian Sarcoma Viruses; Calcium-Binding Proteins; Cell Line; Cell Transformation, Viral; Cytoskeletal Proteins; Molecular Weight; Muscle Proteins; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphotyrosine; Receptors, Fibronectin; Receptors, Immunologic; Retroviridae Proteins; Tyrosine; Vinculin | 1988 |
Vanadate-treated baby hamster kidney fibroblasts show cytoskeleton and adhesion patterns similar to their Rous sarcoma virus-transformed counterparts.
Topics: Actin Cytoskeleton; Animals; Avian Sarcoma Viruses; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Cytoskeleton; Fibroblasts; Kidney; Phenotype; Phosphoproteins; Phosphotyrosine; Tyrosine; Vanadates | 1988 |
A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner.
Topics: Alleles; Animals; Avian Sarcoma Viruses; Base Sequence; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; DNA, Viral; L Cells; Molecular Sequence Data; Mutation; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Retroviridae Proteins; Substrate Specificity; Tyrosine | 1989 |
Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Immunosorbent Techniques; Kinetics; Oncogene Protein pp60(v-src); Phosphoenolpyruvate; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Pyruvate Kinase; Retroviridae Proteins; Tyrosine | 1988 |
Characterization of partially activated p60c-src in chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Enzyme Activation; Extracellular Matrix; Fibroblasts; Oncogene Protein pp60(v-src); Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; Retroviridae Proteins; Tyrosine | 1989 |
Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies.
Topics: Animals; Antibodies; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Kinetics; Mutation; Oncogenes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Tyrosine | 1988 |
Most of the substrates of oncogenic viral tyrosine protein kinases can be phosphorylated by cellular tyrosine protein kinases in normal cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Avian Sarcoma Viruses; Blotting, Western; Cell Line; Cell Transformation, Viral; Mice; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; Rats; Retroviridae Proteins; Substrate Specificity; Tyrosine | 1988 |
Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Glycosylation; Integrins; Membrane Glycoproteins; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Trypsin; Tunicamycin; Tyrosine | 1989 |
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton.
Topics: Animals; Antibodies, Monoclonal; Avian Sarcoma Viruses; Blotting, Western; Cell Transformation, Viral; Chick Embryo; Cytoskeletal Proteins; Fluorescent Antibody Technique; Molecular Weight; Phosphoproteins; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Tyrosine | 1989 |
Ultrastructure and gold-immunolabelling of cell-substratum adhesions (podosomes) in RSV-transformed BHK cells.
Topics: Animals; Avian Sarcoma Viruses; Calcium-Binding Proteins; Cell Adhesion; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytoskeletal Proteins; Gelsolin; Gold; Immunohistochemistry; Microfilament Proteins; Microscopy, Electron; Oncogene Protein pp60(v-src); Phosphotyrosine; Rosette Formation; Tyrosine; Vinculin | 1989 |
Increased phosphorylation of tyrosine in vinculin does not occur upon transformation by some avian sarcoma viruses.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeleton; Muscle Proteins; Phosphorylation; Phosphotyrosine; Tyrosine; Vinculin | 1985 |