phosphotyrosine has been researched along with Carcinoma, Hepatocellular in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 14 (46.67) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Alaggio, R; Alisi, A; Castellano, A; D'Oria, V; De Stefanis, C; Francalanci, P; Giovannoni, I; Grimaldi, C; Romito, I | 1 |
| Huang, X; Li, Y; Ma, K; Zhang, J; Zhong, W | 1 |
| Chai, H; Chen, S; Cheng, F; Deng, L; Dong, T; Sun, D; Xiong, X; Yan, Y; Yu, Y | 1 |
| Barrera, AZ; Bas, M; Chen, X; Dong, G; Hofauer, B; Hou, Y; Ji, Y; Jiao, Y; Knopf, A; Li, F; Li, Q; Li, W; Li, Z; Liu, Z; Lu, X; Ma, F; Mansour, N; Muñoz, RF; Ng, R; Ren, D; Ren, J; Song, G; Steer, CJ; Stock, KF; Strassen, U; Tang, R; Wickham, RE; Wu, H; Xu, Y; You, M; Yue, H; Zhang, H | 1 |
| Canfrán-Duque, A; García-Oya, I; González-Yanes, C; Martínez de Ubago, M; Pérez-Pérez, A; Quintana-Portillo, R; Rodríguez de Fonseca, F; Sánchez-Margalet, V | 1 |
| Carr, BI; Wang, M; Wang, Z | 1 |
| Bache, KG; Madshus, IH; Mehlum, A; Raiborg, C; Stenmark, H | 1 |
| Ramachandran, C; Waddleton, D; Wang, Q | 1 |
| Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A | 1 |
| Chen, J; Cui, JF; Dai, Z; Feng, JT; Liu, YK; Shen, HL; Song, HY; Sun, RX; Zhang, LJ; Zhu, YS | 1 |
| Danaher, M; Fallon, RJ; Saxena, A; Saylors, RL | 1 |
| Chen, DS; Chiou, LL; Horng, MC; Huang, GT; Lai, MY; Lee, HS; Lee, SC; Sheu, JC | 1 |
| Pessin, JE; Yamauchi, K | 1 |
| Bhavani, K; Brown, NV; de la Monte, S; Sasaki, Y; Wands, JR; Xu, YY | 1 |
| Carlton, GW; Culouscou, JM; Green, JM; Plowman, GD; Shoyab, M | 1 |
| Hamburger, AW; Mishra, S | 1 |
| Cheng, LY; Mack, P; Wang, DF; Yang, EB | 1 |
| Tanaka, S; Wands, JR | 1 |
| Chang, HM; Chuang, LM; Lee, SC; Wang, PH | 1 |
| Hocke, GM; Nemetz, C; Piekorz, RP | 1 |
| Anai, M; Asano, T; Fukushima, Y; Funaki, M; Ichimura, T; Inukai, K; Isobe, T; Kikuchi, M; Ogihara, T; Oka, Y; Onishi, Y; Sakoda, H; Taoka, M; Yazaki, Y | 1 |
| Carr, BI; Ni, R; Nishikawa, Y | 1 |
| Hatase, O; Masaki, T; Nishioka, M; Okada, M; Omata, M; Shirai, M; Shiratori, Y; Tokuda, M | 1 |
| Denk, H; Fuchsbichler, A; Hauser, H; Heid, H; Stumptner, C; Zatloukal, K | 1 |
| Dansi, P; Desiderio, MA; Matteucci, E; Tacchini, L | 1 |
| Decaux, JF; Girard, J; Sawka-Verhelle, D; Tartare-Deckert, S; Van Obberghen, E | 1 |
| Goldstein, BJ; Mahadev, K; Zhu, L; Zilbering, A | 1 |
| Carloni, V; Cordella, C; Gentilini, P; Laffi, G; Mazzocca, A; Pantaleo, P | 1 |
| Backer, JM; Collinson, LM; Futter, CE; Hopkins, CR | 1 |
| Hirasa, M; Ogawa, R; Ohtsuka, M; Sasadaira, H; Uchida, H; Watanabe, Y; Yabe, H | 1 |
30 other study(ies) available for phosphotyrosine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Focal Adhesion Kinase (FAK) Over-Expression and Prognostic Implication in Pediatric Hepatocellular Carcinoma.
Topics: beta Catenin; Carcinoma, Hepatocellular; Cell Nucleus; Child; Enhancer of Zeste Homolog 2 Protein; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Cirrhosis; Liver Neoplasms; Lysine; Male; Methylation; Phosphorylation; Phosphotyrosine; Prognosis; Proliferating Cell Nuclear Antigen; Tumor Burden; Up-Regulation | 2020 |
Ganglioside GM3 promotes HGF-stimulated motility of murine hepatoma cell through enhanced phosphorylation of cMet at specific tyrosine sites and PI3K/Akt-mediated migration signaling.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Down-Regulation; G(M2) Ganglioside; G(M3) Ganglioside; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Signal Transduction; Up-Regulation | 2013 |
Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture.
Topics: Adult; Aged; Aged, 80 and over; bcl-X Protein; Carcinoma, Hepatocellular; Cell Nucleus; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Middle Aged; Phosphorylation; Phosphotyrosine; Pyruvate Kinase; STAT3 Transcription Factor; Transcription Factor RelA; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation; Young Adult | 2015 |
Topics: Acute Disease; Adenoma; Adenoma, Pleomorphic; Adolescent; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Animals; Antigens, CD; B-Lymphocytes; Carcinogenesis; Carcinoma, Hepatocellular; CD4-Positive T-Lymphocytes; Diet, High-Fat; Down-Regulation; Elasticity Imaging Techniques; Female; Gene Expression Profiling; Gene Expression Regulation; Hep G2 Cells; HIV Infections; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Integrins; Interferon-alpha; Lipid Metabolism; Liver; Liver Neoplasms; Lupus Erythematosus, Systemic; Lymphocyte Depletion; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; MicroRNAs; Middle Aged; Multimodal Imaging; Non-alcoholic Fatty Liver Disease; Oligonucleotides, Antisense; Parotid Gland; Parotid Neoplasms; Phenotype; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Predictive Value of Tests; Protein-Tyrosine Kinases; Reoperation; Signal Transduction; Spleen; src-Family Kinases; STAT2 Transcription Factor; Sterol Regulatory Element Binding Protein 1; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Toll-Like Receptor 7; Toll-Like Receptor 9; Tumor Suppressor Protein p53; Ultrasonography, Doppler, Color; Young Adult | 2015 |
Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Ligands; Liver Neoplasms; MAP Kinase Signaling System; Oleic Acids; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphotyrosine; PPAR alpha; Pyrimidines; Rats; Receptor, Insulin; Signal Transduction | 2009 |
Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells.
Topics: Actins; Benzenesulfonates; Carcinoma, Hepatocellular; Cofilin 1; Cytoskeleton; Enzyme Activation; Humans; Liver Neoplasms; Models, Biological; Niacinamide; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-met; Pyridines; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Signal Transduction; Sorafenib | 2010 |
Phosphorylation of Hrs downstream of the epidermal growth factor receptor.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; CSK Tyrosine-Protein Kinase; Endosomal Sorting Complexes Required for Transport; Endosomes; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Genes, src; HeLa Cells; Humans; Liver Neoplasms; Mice; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2002 |
Development of a time-resolved fluorescent assay for measuring tyrosine-phosphorylated proteins in cells.
Topics: Animals; Antibodies, Monoclonal; Biotinylation; Blotting, Western; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Europium; Fluoroimmunoassay; Insulin; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Tumor Cells, Cultured | 2002 |
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids.
Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine | 2005 |
[Differential analysis of tyrosine-phosphorylated proteins in human hepatocellular carcinoma cell lines with different metastasis potentials].
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Humans; Liver Neoplasms; Neoplasm Metastasis; Neoplasm Proteins; Phosphotyrosine | 2005 |
Defective asialoglycoprotein receptor endocytosis mediated by tyrosine kinase inhibitors. Requirement for a tyrosine in the receptor internalization signal.
Topics: Adenosine Triphosphate; Alkaloids; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Catechols; Cell Line; Endocytosis; Genistein; Humans; Isoflavones; Kinetics; Liver Neoplasms; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Transferrin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Lack of critical domains in the beta-chain of hepatocyte growth factor.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Dogs; Hepatocyte Growth Factor; Humans; Liver; Liver Neoplasms; Macromolecular Substances; Mice; Mutagenesis; Phosphotyrosine; Polymerase Chain Reaction; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Deletion; Spodoptera; Transfection; Tumor Cells, Cultured; Tyrosine | 1995 |
Epidermal growth factor-induced association of the SHPTP2 protein tyrosine phosphatase with a 115-kDa phosphotyrosine protein.
Topics: 3T3 Cells; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; Tumor Cells, Cultured; Tyrosine | 1995 |
Effect of ethanol on p36 protein kinase substrate and insulin receptor substrate 1 expression and tyrosyl phosphorylation in human hepatocellular carcinoma cells.
Topics: Annexin A2; Carcinoma, Hepatocellular; Cell Division; Cell Line; DNA Replication; Ethanol; Gene Expression Regulation, Enzymologic; Humans; Insulin Receptor Substrate Proteins; Liver Neoplasms; Phosphoproteins; Phosphorylation; Phosphotyrosine; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1995 |
Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Differentiation; CHO Cells; Chromatography; Cricetinae; ErbB Receptors; Glycoproteins; Humans; Liver Neoplasms; Molecular Sequence Data; Molecular Weight; Neuregulins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Receptor, ErbB-4; Receptors, Cell Surface; Recombinant Proteins; Tumor Cells, Cultured; Tyrosine | 1993 |
Association of inhibition of cell growth by O-phospho-L-tyrosine with decreased tyrosine phosphorylation.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Drug Interactions; Female; Humans; Insulin; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Receptor, ErbB-2; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine | 1996 |
Genistein, a tyrosine kinase inhibitor, reduces EGF-induced EGF receptor internalization and degradation in human hepatoma HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Isoflavones; Kinetics; Liver Neoplasms; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1996 |
A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Humans; Insulin Receptor Substrate Proteins; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Phosphoproteins; Phosphotyrosine; Receptor, IGF Type 1; Receptor, Insulin; Sequence Deletion; Signal Transduction; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured | 1996 |
Novel pathway of insulin signaling involving Stat1alpha in Hep3B cells.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleotides; DNA-Binding Proteins; Immunoblotting; Insulin; Interferon-Stimulated Gene Factor 3; Interleukin-4; Nuclear Proteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Signal Transduction; Transcription Factors; Tumor Cells, Cultured | 1997 |
Members of the family of IL-6-type cytokines activate Stat5a in various cell types.
Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA-Binding Proteins; Gene Expression Regulation; Growth Inhibitors; Humans; Interleukin-6; Leukemia; Leukemia Inhibitory Factor; Liver Neoplasms; Lymphokines; Mice; Milk Proteins; Phosphotyrosine; Protein Binding; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.
Topics: 14-3-3 Proteins; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Brain; Carcinoma, Hepatocellular; Cattle; Cell Line; CHO Cells; Cricetinae; Gene Library; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Mice; Molecular Sequence Data; Myocardium; Okadaic Acid; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein Biosynthesis; Proteins; Rats; Receptor, Insulin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spodoptera; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1997 |
Cell growth inhibition by a novel vitamin K is associated with induction of protein tyrosine phosphorylation.
Topics: Carcinoma, Hepatocellular; Catechols; Cell Division; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Humans; Kinetics; Liver Neoplasms; Mercaptoethanol; Naphthoquinones; Nitriles; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sulfhydryl Compounds; Tumor Cells, Cultured; Tyrphostins; Vanadates; Vitamin K | 1998 |
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma.
Topics: Aged; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; CSK Tyrosine-Protein Kinase; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Inbred LEC; Rats, Wistar; src-Family Kinases | 1999 |
Identification of p62, a phosphotyrosine independent ligand of p56lck kinase, as a major component of intracytoplasmic hyaline bodies in hepatocellular carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoma, Hepatocellular; Cytoplasm; Humans; Inclusion Bodies; Liver Neoplasms; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Phosphotyrosine; Sequestosome-1 Protein | 1999 |
Hepatocyte growth factor signal coupling to various transcription factors depends on triggering of Met receptor and protein kinase transducers in human hepatoma cells HepG2.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipper Transcription Factors; Carcinoma, Hepatocellular; Dimerization; DNA-Binding Proteins; Hepatocyte Growth Factor; Humans; Liver Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Protein Kinase C; Proto-Oncogene Proteins c-met; Signal Transduction; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Tumor Cells, Cultured | 2000 |
Stat 5B, activated by insulin in a Jak-independent fashion, plays a role in glucokinase gene transcription.
Topics: 3T3 Cells; Animals; Carcinoma, Hepatocellular; DNA; DNA-Binding Proteins; Glucokinase; Humans; Insulin; Insulin-Like Growth Factor I; Janus Kinase 1; Janus Kinase 2; Liver; Liver Neoplasms; Mice; Milk Proteins; Mutagenesis, Site-Directed; Phosphotyrosine; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; STAT5 Transcription Factor; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Dexamethasone; Humans; Hydrogen Peroxide; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms; Mice; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Tumor Cells, Cultured | 2001 |
The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells.
Topics: Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Collagen; Culture Media; Enzyme Activation; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha6beta1; Integrins; Kinetics; Laminin; Liver Neoplasms; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 2001 |
Human VPS34 is required for internal vesicle formation within multivesicular endosomes.
Topics: Androstadienes; Antibodies, Monoclonal; Autocrine Communication; Carcinoma, Hepatocellular; Coated Vesicles; Endosomes; Epidermal Growth Factor; ErbB Receptors; Humans; Lysosomes; Microinjections; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotyrosine; Protein Transport; Tumor Cells, Cultured; Wortmannin | 2001 |
Increase of phosphotyrosine-containing proteins in human carcinomas.
Topics: Carcinoma; Carcinoma, Hepatocellular; Chromatography, Affinity; Esophageal Neoplasms; Fluorescent Antibody Technique; Humans; Liver Neoplasms; Molecular Weight; Neoplasm Proteins; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Stomach Neoplasms; Tissue Distribution; Tyrosine | 1985 |