phosphotyrosine has been researched along with Carcinoma, Epidermoid in 46 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 11 (23.91) | 18.7374 |
1990's | 24 (52.17) | 18.2507 |
2000's | 7 (15.22) | 29.6817 |
2010's | 4 (8.70) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Chen, W; Deng, R; Han, Z; Hanada, S; Liu, Y; Wang, X; Xu, Q; Yan, M; Zhang, J; Zhang, P | 1 |
Barbhuiya, MA; Chatterjee, A; Datta, KK; Gowda, H; Khan, AA; Kumar, MV; Kumar, RV; Nirujogi, RS; Pandey, A; Pinto, SM; Prasad, TS; Renuse, S; Srikumar, K; Syed, N | 1 |
Balaji, SA; Califano, JA; Chatterjee, A; Chavan, S; Gowda, H; Jain, AP; Kumar, MM; Mathur, PP; Nanjappa, V; Pandey, A; Pinto, SM; Prasad, TS; Puttamallesh, VN; Radhakrishnan, A; Raja, R; Rangarajan, A; Sahasrabuddhe, NA; Santosh, V; Sathe, G; Sidransky, D; Sukumar, G | 1 |
Jadwin, JA; Machida, K; Mayer, BJ; Ogiue-Ikeda, M; Oh, D; Yu, J | 1 |
Estrada, C; Hernández-Hernando, S; Jiménez, A; Ruano, MJ; Villalobo, A | 1 |
Gooding, WE; Grandis, JR; Li, M; Lui, VW; Niwa, H; Wentzel, AL | 1 |
Gu, J; Honke, K; Ihara, S; Inohara, H; Kubo, T; Miyoshi, E; Nakahara, S; Noda, K; Taniguchi, N | 1 |
Fenyo, D; Gibson, N; Griffin, G; Haley, JD; Hunt, T; Iwata, K; Petti, F; Settinari, T; Thelemann, A | 1 |
Ando, E; Furuta, M; Nakanishi, T; Nishimura, O; Tsunasawa, S | 1 |
Collins, B; Gooding, WE; Grandis, JR; Handler, PN; Seethala, RR; Siegfried, JM; Zhang, Q | 1 |
Cohen, S; Ushiro, H | 1 |
Bornstein, P; Brautigan, DL; Gallis, B | 1 |
Erikson, RL; Shealy, DJ | 1 |
Bornstein, P; Casnellie, JE; Gallis, B; Krebs, EG; Pike, LJ | 1 |
Cohen, S | 1 |
Hakomori, S; Igarashi, Y; Kitamura, K; Zhou, Q | 1 |
Daya-Makin, M; Hogg, JC; Lipp, M; Mogentale, TL; Parchomchuk, J; Pelech, SL; Sanghera, JS | 1 |
Kramer, RH; Matsumoto, K; Nakamura, T | 1 |
Doki, Y; Inoue, M; Iwazawa, T; Kadowaki, T; Matsui, S; Oka, H; Shimaya, K; Shiozaki, H; Takeichi, M; Tamura, S | 1 |
Jia, XS; Sun, AJ; Zhang, DR | 1 |
Cantey, JR; Dytoc, MT; Ismaili, A; Philpott, DJ; Sherman, PM | 1 |
Anderson, JM; Balda, MS; Van Itallie, CM | 1 |
Katoh, I; Kyushiki, H; Sakamoto, Y; Yoshinaka, Y | 1 |
Feghali, CA; Wright, TM | 1 |
Campbell, DL; Carbonaro-Hall, D; Hall, F; Pelech, S; Sanghera, J; Warburton, D; Williams, R; Wu, F | 1 |
Fogleman, PB; Schmidt-Ullrich, RK; Valerie, K; Walters, J | 1 |
Chen, PB; Contessa, JN; Dent, P; Kavanagh, BD; Mikkelsen, RB; Rorrer, WK; Schmidt-Ullrich, RK; Todd, DG; Valerie, K | 1 |
Chen, CF; Liang, YC; Lin, JK; Lin-shiau, SY | 1 |
Baba, S; Furukawa, F; Takigawa, M; Wakita, H | 1 |
Kuan, CY; Lee, SC; Wen, ZD; Yang, SD | 1 |
Cross, CE; Eiserich, JP; Goldkorn, T; Hristova, M; van der Vliet, A | 1 |
Theunissen, HJ; van den Doelen, AA; Veeneman, GH; Vink, PM; Zaman, GJ | 1 |
Mercurio, AM; Rabinovitz, I; Toker, A | 1 |
Fan , G; Malbon, CC; Shumay, E; Wang , H | 1 |
Moolenaar, WH; Ploegh, HL; Verheijden, GF | 1 |
Brock, T; Kahn, CR; Karasik, A; Pepinsky, RB; Reddy, SS | 1 |
Nesterov, A; Nikolsky, N; Reshetnikova, G; Vinogradova, N | 1 |
Nesterov, AM; Nikol'skiĭ, NN; Reshetnikova, GF; Sorkin, AD; Vinogradova, NA | 1 |
Kan, M; Kayada, Y; Myoken, Y; Okamoto, T; Sato, GH; Sato, JD | 1 |
Kornilova, ES; Nesterov, AM; Nikol'skiĭ, NN; Vdovina, IB | 1 |
Evans, RM; Gamou, S; Gill, GN; Lin, C; Rosenfeld, MG; Shimizu, N; Thompson, DM; Weber, W | 1 |
Landreth, GE; Rieser, GD; Williams, LK | 1 |
Bremer, EG; Hakomori, S; Schlessinger, J | 1 |
Cooper, JA; King, CS; Moss, B; Twardzik, DR | 1 |
Izumi, T; Kadowaki, T; Kasuga, M; Koyasu, S; Nishida, E; Sakai, H; Takaku, F; Tobe, K; Yahara, I | 1 |
Carpenter, G; Daniel, TO; Wahl, MI | 1 |
1 review(s) available for phosphotyrosine and Carcinoma, Epidermoid
Article | Year |
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Direct on-membrane peptide mass fingerprinting with MALDI-MS of tyrosine-phosphorylated proteins detected by immunostaining.
Topics: Antibodies, Phospho-Specific; Blotting, Western; Carcinoma, Squamous Cell; Cell Extracts; Cell Line, Tumor; Cell Membrane; Electrophoresis, Gel, Two-Dimensional; Epidermal Growth Factor; Humans; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphotyrosine; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2007 |
45 other study(ies) available for phosphotyrosine and Carcinoma, Epidermoid
Article | Year |
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A new gamboge derivative compound 2 inhibits cancer stem-like cells via suppressing EGFR tyrosine phosphorylation in head and neck squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Spheroids, Cellular; Tumor Burden; Xanthones; Xenograft Model Antitumor Assays | 2013 |
Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous-cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Ephrin-A2; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagus; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mass Spectrometry; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction | 2015 |
A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma.
Topics: Animals; Apoptosis; bcl-X Protein; Carcinoma, Squamous Cell; Caspase 9; Cell Line; Cell Movement; Dyrk Kinases; Female; Forkhead Box Protein O3; Harmine; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Nude; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Small Molecule Libraries; Squamous Cell Carcinoma of Head and Neck; Tandem Mass Spectrometry; Tissue Array Analysis; Transplantation, Heterologous | 2016 |
Fast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane.
Topics: Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Membrane; Diffusion; ErbB Receptors; Humans; Kinetics; Lung Neoplasms; Microscopy; Models, Chemical; Phosphorylation; Phosphotyrosine; Protein Structure, Tertiary; Signal Transduction; src Homology Domains | 2012 |
Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells.
Topics: Carcinoma, Squamous Cell; DNA, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Humans; Hydrazines; Kinetics; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Thymidine; Tumor Cells, Cultured | 2003 |
Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Coloring Agents; DNA-Binding Proteins; Docetaxel; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Transplantation; Oligonucleotides, Antisense; Phosphotyrosine; Signal Transduction; STAT3 Transcription Factor; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Vascular Endothelial Growth Factor A | 2003 |
Involvement of oligosaccharide changes in alpha5beta1 integrin in a cisplatin-resistant human squamous cell carcinoma cell line.
Topics: Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha5beta1; Lectins; Oligosaccharides; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases | 2003 |
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Chromatography, Affinity; Chromatography, Liquid; Enzyme Activation; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Immunoblotting; Isotopes; Mass Spectrometry; Models, Biological; Peptide Mapping; Phosphorylation; Phosphotyrosine; Proteins; Quinazolines; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src-Family Kinases | 2005 |
Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cohort Studies; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Phosphotyrosine; Receptors, Bombesin; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Transforming Growth Factor alpha | 2008 |
Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Chromatography, Thin Layer; Electrophoresis, Paper; Enzyme Activation; Epidermal Growth Factor; Humans; Membrane Proteins; Peptides; Phosphotyrosine; Protein Kinases; Tyrosine | 1980 |
Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn.
Topics: Carcinoma, Squamous Cell; Cations, Divalent; Cell Line; Cell Membrane; Humans; Kinetics; Membrane Proteins; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Tyrosine; Zinc | 1981 |
Human cells contain two forms of pp60c-src.
Topics: Carcinoma, Squamous Cell; Fibroblasts; Humans; Molecular Weight; Neoplasm Proteins; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphoproteins; Phosphotyrosine; Tyrosine; Viral Proteins | 1981 |
Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphoproteins; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1982 |
Purification of the receptor for epidermal growth factor from A-431 cells: its function as a tyrosyl kinase.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Molecular Weight; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Radioisotope Dilution Technique; Receptors, Cell Surface; Tyrosine | 1983 |
GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Dogs; ErbB Receptors; Erythrocytes; G(M3) Ganglioside; Humans; Kinetics; Macromolecular Substances; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Tumor Cells, Cultured; Tyrosine | 1994 |
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung.
Topics: Adenocarcinoma; Amino Acid Sequence; Antibodies; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Casein Kinases; Caseins; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lung; Lung Neoplasms; Molecular Sequence Data; Myelin Basic Protein; Peptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Substrate Specificity; Tyrosine | 1994 |
Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells.
Topics: Benzoquinones; Carcinoma, Squamous Cell; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Hepatocyte Growth Factor; Humans; In Vitro Techniques; Integrins; Lactams, Macrocyclic; Mouth Neoplasms; Neoplasm Invasiveness; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-met; Quinones; Receptor Protein-Tyrosine Kinases; Rifabutin; Tumor Cells, Cultured; Tyrosine | 1994 |
Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line.
Topics: alpha Catenin; Benzoquinones; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Aggregation; Cell Line; Culture Techniques; Cytoskeletal Proteins; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Fibroblasts; Fluorescent Antibody Technique; Gels; Humans; Lactams, Macrocyclic; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Quinones; Rifabutin; Signal Transduction; Trans-Activators; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine; Vanadates | 1995 |
[The expression of C-FOS, C-JUN and phosphotyrosine gene products in lung cancer].
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Gene Expression; Humans; Lung Neoplasms; Phosphotyrosine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tyrosine | 1994 |
Increased adherence of Escherichia coli RDEC-1 to human tissue culture cells results in the activation of host signaling pathways.
Topics: Actinin; Animals; Bacterial Adhesion; Carcinoma, Squamous Cell; Cell Line; Cell Line, Transformed; Diarrhea; Epithelium; Escherichia coli; Escherichia coli Infections; Fluorescent Antibody Technique; Humans; Intestines; Phosphotyrosine; Plasmids; Rabbits; Signal Transduction; Species Specificity; Tumor Cells, Cultured; Tyrosine | 1995 |
Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells.
Topics: Actins; Blotting, Western; Carcinoma, Squamous Cell; Cell Line; Cytochalasin D; Epidermal Growth Factor; Humans; Intercellular Junctions; Membrane Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine; Zonula Occludens-1 Protein | 1995 |
Alterations of the cytoskeletal organization in tumor cell lines by a cardiotonic drug, vesnarinone, through protein tyrosine phosphorylation.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Carcinoma, Squamous Cell; Cardiotonic Agents; Catechols; Cell Communication; Cell Line; Cell Line, Transformed; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Genes, src; Humans; Immunoblotting; Lung Neoplasms; Mice; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Pyrazines; Quinolines; Tubulin; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vimentin | 1995 |
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.
Topics: Adenosine Triphosphate; Antibodies; Base Sequence; Carcinoma, Squamous Cell; Cell Line; Cell-Free System; Cytosol; Humans; Interferon-gamma; Kinetics; Leukemia, Myeloid; Ligands; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Repetitive Sequences, Nucleic Acid; Skin Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Identification of a human epidermal growth factor receptor-associated protein kinase as a new member of the mitogen-activated protein kinase/extracellular signal-regulated protein kinase family.
Topics: Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Humans; Isoenzymes; Kidney Neoplasms; Molecular Sequence Data; Molecular Weight; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Proteins; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Wilms Tumor | 1993 |
Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells.
Topics: Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cobalt Radioisotopes; Confidence Intervals; Dose-Response Relationship, Radiation; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Kinetics; Phosphorylation; Phosphotyrosine; Signal Transduction; Tumor Cells, Cultured; Up-Regulation | 1996 |
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation.
Topics: Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Division; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Nitriles; Phospholipase C gamma; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinazolines; Radiation, Ionizing; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 1997 |
Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Division; DNA, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Humans; Ligands; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tea; Tumor Cells, Cultured | 1997 |
Human squamous-cell-carcinoma cell line (DJM-1) cells synthesize P-cadherin molecules via an elevation of extracellular calcium: calcium regulates P-cadherin-gene expression at the translational level via protein tyrosine phosphorylation.
Topics: Base Sequence; Cadherins; Calcium; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Membrane; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; RNA, Messenger; Skin Neoplasms; Tumor Cells, Cultured | 1997 |
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway.
Topics: Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Squamous Cell; Enzyme Activation; Enzyme Induction; Genistein; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase C; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1998 |
Peroxynitrite induces covalent dimerization of epidermal growth factor receptors in A431 epidermoid carcinoma cells.
Topics: Carbodiimides; Carcinoma, Squamous Cell; Cell Division; Cross-Linking Reagents; Dimerization; ErbB Receptors; Humans; Isoenzymes; Kinetics; Molecular Weight; Nitrates; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Tyrosine kinase activity of purified recombinant cytoplasmic domain of platelet-derived growth factor beta-receptor (beta-PDGFR) and discovery of a novel inhibitor of receptor tyrosine kinases.
Topics: 3T3 Cells; Animals; Becaplermin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cytoplasm; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factor 2; Growth Substances; Humans; Indoles; Kinetics; Mice; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1999 |
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells.
Topics: Actins; Antigens, Surface; Carbazoles; Carcinoma, Squamous Cell; Cell Membrane; Cell Size; Chemotaxis; Desmosomes; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Integrin alpha6beta4; Integrins; Keratins; Laminin; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Pseudopodia; Signal Transduction; Tumor Cells, Cultured | 1999 |
c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization.
Topics: Adrenergic beta-Agonists; Amino Acid Substitution; Animals; beta-Adrenergic Receptor Kinases; Binding Sites; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Genes, Reporter; Green Fluorescent Proteins; Humans; Iodocyanopindolol; Isoproterenol; Luminescent Proteins; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; src Homology Domains; src-Family Kinases; Transfection; Tumor Cells, Cultured | 2001 |
Retention of epidermal growth factor receptors in the endoplasmic reticulum of adenovirus-infected cells.
Topics: Adenoviruses, Human; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Membrane; Down-Regulation; Endoplasmic Reticulum; ErbB Receptors; Histocompatibility Antigens Class I; Humans; KB Cells; Kinetics; Oligosaccharides; Phosphotyrosine; Receptors, Transferrin; Time Factors; Tyrosine | 1992 |
Augmented desensitization to epidermal growth factor (EGF) immediate actions: a novel mechanism for altered EGF growth response in mutant A431 cells.
Topics: Annexins; Calcium; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Division; Cytoplasm; Drug Tolerance; Epidermal Growth Factor; ErbB Receptors; Humans; Mutation; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine | 1990 |
Functional state of the epidermal growth factor-receptor complexes during their internalization in A-431 cells.
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine | 1990 |
[The immunofluorescent detection of phosphorylated receptors of the epidermal growth factor during their internalization in A-431 cells].
Topics: Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Phosphorylation; Phosphotyrosine; Staining and Labeling; Temperature; Tumor Cells, Cultured; Tyrosine | 1990 |
Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites.
Topics: Amino Acid Sequence; Binding Sites; Carcinoma, Squamous Cell; Cell Membrane; Endothelial Growth Factors; Endothelium, Vascular; Humans; In Vitro Techniques; Lymphokines; Molecular Sequence Data; Molecular Weight; Phosphoproteins; Phosphotyrosine; Receptors, Mitogen; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Temperature; Time Factors; Tumor Cells, Cultured; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1991 |
[The direct demonstration of the tyrosine phosphorylation of epidermal growth factor receptors internalized in the endosomes of A431 cells].
Topics: Antibodies; Carcinoma, Squamous Cell; Cell Fractionation; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; Organelles; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine | 1991 |
Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; Chromosomes, Human, 6-12 and X; Clone Cells; Epidermal Growth Factor; ErbB Receptors; Gene Amplification; Humans; Neoplasm Proteins; Phosphoproteins; Phosphotyrosine; Receptors, Cell Surface; RNA, Messenger; RNA, Neoplasm; Translocation, Genetic; Tyrosine | 1985 |
Association of the epidermal growth factor receptor kinase with the detergent-insoluble cytoskeleton of A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Line; Cytoskeleton; Epidermal Growth Factor; ErbB Receptors; Humans; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cell Surface; Tyrosine | 1985 |
Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.
Topics: Amino Acids; Animals; Carcinoma, Squamous Cell; Cattle; Cell Division; Cell Line; Depression, Chemical; Dogs; Epidermal Growth Factor; ErbB Receptors; Female; Fibroblasts; G(M1) Ganglioside; G(M3) Ganglioside; Gangliosides; Humans; Immunosorbent Techniques; Mice; Mouth Neoplasms; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Receptors, Cell Surface; Tyrosine | 1986 |
Vaccinia virus growth factor stimulates tyrosine protein kinase activity of A431 cell epidermal growth factor receptors.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Viral; Enzyme Activation; ErbB Receptors; Growth Substances; Humans; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vaccinia virus; Viral Proteins | 1986 |
Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell.
Topics: Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Immunosorbent Techniques; Insulin; Insulin-Like Growth Factor I; Molecular Weight; Phosphorylation; Phosphotyrosine; Proteins; Receptor, Insulin; Receptors, Somatomedin; Somatomedins; Tyrosine | 1987 |
Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells.
Topics: Antibodies; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Cytosol; Epidermal Growth Factor; Hydrolysis; Inositol Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Substrate Specificity; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1988 |