Compounds > phosphotyrosine
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phosphotyrosine and Bone Loss, Osteoclastic

phosphotyrosine has been researched along with Bone Loss, Osteoclastic in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amugongo, S; Dai, W; Guan, M; Jia, J; Lam, KS; Lane, NE; Lay, YA; Liu, R; Nolta, J; Olivos, D; Olvera, D; Ritchie, RO; Saunders, M; Yao, W1
Arai, Y; Hakeda, Y; Kaneda, T; Kobayashi, Y; Kumegawa, M; Sato, T; Shin, K; Ueyama, S; Yoshida, Y1
Machida, K; Mayer, BJ1
Amoui, M; Baylink, DJ; Chen, ST; Lau, KH; Sheng, MH1
Kurokawa, T; Murakami, H; Nakamura, I; Suda, T; Takahashi, N; Tanaka, S; Udagawa, N1
Abe, M; Barbier, A; Konno, F; Murakami, H; Nakajo, S; Nakamura, I; Nakaya, K; Suda, T; Takahashi, N; Tanaka, S; Udagawa, N; Yuda, Y1
Adams, S; Azimioara, M; Bartlett, C; Bohacek, R; Cerasoli, F; Dalgarno, D; Guan, W; Haraldson, C; Hatada, M; Herson, J; Iuliucci, J; Lu, X; Merry, T; Metcalf, C; Narula, S; Pradeepan, S; Sawyer, T; Shakespeare, W; Smith, J; Stebbins, K; Sundaramoorthi, R; van Schravendijk, MR; Violette, S; Vu, C; Weigele, M; Yang, M1
Bohacek, RS; Dalgarno, DC; Hatada, M; Jacobsen, VA; Lynch, BA; Macek, KJ; Merry, T; Metcalf, CA; Narula, SS; Sawyer, TK; Shakespeare, WC; Violette, SM; Weigele, M1
Bartlett, C; Bohacek, RS; Dalgarno, DC; Eyermann, CJ; Guan, W; Hatada, M; Johnson, D; Kawahata, N; Lu, X; Luke, GP; Merry, T; Sawyer, TK; Shakespeare, WC; Smith, J; Sundaramoorthi, R; Violette, S; Wang, Y; Yang, MG1

Reviews

1 review(s) available for phosphotyrosine and Bone Loss, Osteoclastic

ArticleYear
The SH2 domain: versatile signaling module and pharmaceutical target.
    Biochimica et biophysica acta, 2005, Feb-14, Volume: 1747, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Bone Resorption; Drug Design; Humans; Molecular Sequence Data; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Signal Transduction; src Homology Domains; src-Family Kinases; Ubiquitin-Protein Ligases

2005

Other Studies

8 other study(ies) available for phosphotyrosine and Bone Loss, Osteoclastic

ArticleYear
Reversing bone loss by directing mesenchymal stem cells to bone.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:9

    Topics: Aging; Alendronate; Animals; Bone and Bones; Bone Resorption; Cell Differentiation; Cell Movement; Dipeptides; Estrogens; Extracellular Matrix; Female; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteogenesis; Phenylurea Compounds; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-akt

2013
The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.
    Journal of bone and mineral metabolism, 2004, Volume: 22, Issue:4

    Topics: Aniline Compounds; Animals; Binding Sites; Bone Resorption; Carrier Proteins; Cell Differentiation; Cell Lineage; Cells, Cultured; Crotonates; Electrophoretic Mobility Shift Assay; Hydroxybutyrates; Isoxazoles; Leflunomide; Membrane Glycoproteins; Mice; NF-kappa B; Nitriles; Osteoclasts; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Toluidines

2004
A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2.
    Archives of biochemistry and biophysics, 2007, Jul-01, Volume: 463, Issue:1

    Topics: Animals; Apoptosis; Bone Resorption; Cell Differentiation; Cell Survival; Mice; Mitogen-Activated Protein Kinase 9; NF-kappa B; Osteoclasts; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); RNA, Small Interfering

2007
Possible involvement of focal adhesion kinase, p125FAK, in osteoclastic bone resorption.
    Journal of cellular biochemistry, 1995, Volume: 58, Issue:4

    Topics: Animals; Animals, Newborn; Base Sequence; Benzoquinones; Bone Marrow Cells; Bone Resorption; Calcitriol; Cattle; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Dentin; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Hematopoietic Stem Cells; Immunohistochemistry; Lactams, Macrocyclic; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Osteoclasts; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Thionucleotides

1995
Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts.
    Bone, 1997, Volume: 20, Issue:5

    Topics: Actins; Animals; Bone Resorption; Cattle; Cells, Cultured; Cytoskeleton; Diphosphonates; Enzyme Inhibitors; Mice; Osteoclasts; Phosphotyrosine; Protein Tyrosine Phosphatases; Signal Transduction

1997
Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-15, Volume: 97, Issue:17

    Topics: Adsorption; Amino Acid Substitution; Animals; Binding Sites; Bone and Bones; Bone Resorption; Citric Acid; Crystallography, X-Ray; Dentin; Diphosphonates; Drug Design; Female; Hydroxyapatites; Inhibitory Concentration 50; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Models, Molecular; Molecular Mimicry; Osteoclasts; Parathyroid Hormone; Parathyroidectomy; Phosphotyrosine; Protein Conformation; Proto-Oncogene Proteins pp60(c-src); Rabbits; Rats; Rats, Wistar; src Homology Domains; Structure-Activity Relationship; Substrate Specificity

2000
X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor.
    Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

    Topics: Animals; Benzamides; Bone and Bones; Bone Resorption; Citric Acid; Crystallography, X-Ray; Cyclohexanes; Durapatite; Enzyme Inhibitors; Ligands; Models, Molecular; Molecular Mimicry; Organophosphorus Compounds; Osteoclasts; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Rabbits; src Homology Domains

2001
A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Animals; Benzamides; Binding Sites; Bone Resorption; Crystallography, X-Ray; Dentin; Drug Design; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Molecular Mimicry; Mutation; Organophosphonates; Osteoclasts; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Rabbits; src Homology Domains; Structure-Activity Relationship

2001