phosphotyrosine has been researched along with Acute Confusional Senile Dementia in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, Z; Fu, J; Liu, J | 1 |
| Akay, LA; Joughin, BA; LaRocque, L; Mastroeni, D; Morshed, N; Nott, A; Pao, PC; Penney, J; Ralvenius, WT; Rodriguez, FH; Tsai, LH; Watson, LA; White, FM | 1 |
| Abou-Fadel, J; Padarti, A; Zhang, J | 1 |
| Almeida-Santos, T; da Cruz E Silva, OA; Martins, S; Ramalho-Santos, J; Sousa, AP; Tavares, RS | 1 |
| Anderson, GM; Baguley, TD; Brouillette, J; Chatterjee, M; Cuny, GD; Ellman, JA; Foscue, E; Ghosh, D; Glicksman, MA; Greengard, P; Gresack, J; Kanyo, J; Kurup, P; Lam, TT; Lombroso, PJ; Nairn, AC; Ononenyi, C; Seyb, K; Tautz, L; Xu, J; Zhang, Y | 1 |
| Geahlen, RL; Ghosh, S | 1 |
| Collins, MA; Mitchell, RM; Neafsey, EJ | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Cini, C; Di Domenico, F; Mancuso, C; Perluigi, M; Preziosi, P; Sultana, R | 1 |
| Combs, CK; Dhawan, G; Floden, AM | 1 |
| Carlo, P; Dolcini, V; Russo, C; Russo, T; Salis, S; Schettini, G; Venezia, V; Violani, E; Zambrano, N | 1 |
| Anderton, BH; Bird, IN; Brion, JP; Byers, HL; Derkinderen, P; Hanger, DP; Kellie, S; Lenz, C; Leroy, K; Leung, KY; Noble, W; Perera, T; Price, C; Reynolds, CH; Scales, TM; Van Etten, RA; Ward, MA; Williamson, R | 1 |
| Eckert, A; Frölich, L; Gorriz, C; Maurer, K; Müller, WE; Peters, J; Schindowski, K; Schramm, U; Weinandi, T | 1 |
| Liu, WK; Yang, SD; Yen, SH; Yu, JS | 1 |
| Fabian, H; Lang, E; Mantsch, HH; Otvos, L; Szendrei, GI | 1 |
| Anderton, BH; Brion, JP; Couck, AM; Loviny, TL; Robertson, J | 1 |
| Aksenova, MV; Burbaeva, GSh; Vener, AV | 1 |
| Lu, Q; Soria, JP; Wood, JG | 1 |
| Donini, V; Duilio, A; Fiore, F; Minopoli, G; Russo, T; Zambrano, N | 1 |
| Borg, JP; Levy, E; Margolis, B; Ooi, J | 1 |
| Buxbaum, JD; Cheetham, J; De Candia, P; De Renzis, S; Faraonio, R; Fiore, F; Minopoli, G; Russo, T; Sabo, S; Sudol, M; Zambrano, N | 1 |
| Blanco, G; Brown, SD; Irving, NG; McLoughlin, DM; Miller, CC | 1 |
| Borg, JP; De Taddéo-Borg, M; Margolis, B; Turner, RS; Yang, Y | 1 |
| Dolcini, V; Russo, C; Salis, S; Schettini, G; Song, XH; Teller, JK; Venezia, V | 1 |
| Hirai, S; Hiraki, T; Homma, Y; Ito, Y; Kawasumi, M; Kita, Y; Kouyama, K; Kyriakis, JM; Matsuda, S; Niikura, T; Nishimoto, I; Ohno, S; Yamamoto, T; Yasukawa, T | 1 |
| Biernat, J; Dorée, M; Döring, F; Drewes, G; Goris, J; Lichtenberg-Kraag, B; Mandelkow, E; Mandelkow, EM | 1 |
| Masliah, E; Saitoh, T; Shapiro, IP | 1 |
| Wood, JG; Zinsmeister, P | 1 |
1 review(s) available for phosphotyrosine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Resurgence of phosphotyrosine binding domains: Structural and functional properties essential for understanding disease pathogenesis.
Topics: Alzheimer Disease; Binding Sites; Diabetes Mellitus; Humans; Hypercholesterolemia; Phosphotyrosine; Stroke | 2021 |
26 other study(ies) available for phosphotyrosine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Comprehensive binary interaction mapping of τ phosphotyrosine sites with SH2 domains in the human genome: Implications for the rational design of self-inhibitory phosphopeptides to target τ hyperphosphorylation signaling in Alzheimer's Disease.
Topics: Alzheimer Disease; Binding Sites; Genome, Human; Humans; Phosphopeptides; Phosphotyrosine; Protein Binding; src Homology Domains | 2022 |
Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Antibodies; Cell Death; Cell Line; Humans; Inflammation; Interferon-gamma; Mice, Transgenic; Microglia; Nerve Degeneration; Peptides; Phagocytosis; Phosphoproteins; Phosphotyrosine; Proteome; Proteomics; Sialic Acid Binding Immunoglobulin-like Lectins; Signal Transduction; Up-Regulation | 2020 |
Alzheimer's disease-related amyloid-β
Topics: Acrosome; Alzheimer Disease; Amyloid beta-Peptides; Calcium; Cell Survival; Humans; Intracellular Space; Male; Mitochondria; Phosphorylation; Phosphotyrosine; Sperm Motility; Spermatozoa | 2017 |
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Benzothiepins; Catalytic Domain; Cell Death; Cerebral Cortex; Cognition Disorders; Cysteine; Disease Models, Animal; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Neurons; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases, Non-Receptor; Substrate Specificity | 2014 |
Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Line; Cytoplasmic Granules; Gene Expression; Genes, Reporter; Humans; Immunoglobulin G; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Microglia; Phagocytosis; Phosphotyrosine; Protein-Tyrosine Kinases; Reactive Nitrogen Species; Reactive Oxygen Species; Stress, Physiological; Syk Kinase | 2015 |
Essential involvement of the NMDA receptor in ethanol preconditioning-dependent neuroprotection from amyloid-betain vitro.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Dose-Response Relationship, Drug; Ethanol; In Vitro Techniques; Neurons; Neuroprotective Agents; Peptide Fragments; Phosphotyrosine; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2009 |
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cognition; Enzyme Activation; Female; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Phosphoserine; Phosphothreonine; Phosphotyrosine; Up-Regulation | 2011 |
Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cells, Cultured; Dasatinib; Female; Humans; Male; Mice; Mice, Inbred C57BL; Microglia; Phosphotyrosine; Plaque, Amyloid; Polymers; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Signal transduction through tyrosine-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.
Topics: Adaptor Proteins, Signal Transducing; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Astrocytes; Brain; Cerebral Cortex; GRB2 Adaptor Protein; Humans; Middle Aged; Peptide Fragments; Phosphorylation; Phosphotyrosine; Proteins; Reference Values; Signal Transduction; src Homology Domains | 2002 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Topics: Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; Brain Chemistry; Cell Line, Tumor; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Female; Fetal Proteins; Humans; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuroblastoma; Neurofibrillary Tangles; Neurons; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-fyn; src-Family Kinases; tau Proteins; Transfection; Vanadates | 2005 |
Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy.
Topics: Aged; Alzheimer Disease; Animals; Apolipoproteins E; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunologic Memory; Immunotherapy; Leukocytes, Mononuclear; Lymphocyte Count; Male; Mice; Mice, Transgenic; Phosphotyrosine | 2007 |
Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's diseased brain tau by kinase FA/GSK-3 alpha.
Topics: Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Humans; Kinetics; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Substrate Specificity; tau Proteins; Tyrosine | 1993 |
Tyrosine- versus serine-phosphorylation leads to conformational changes in a synthetic tau peptide.
Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies, Monoclonal; Genes, Synthetic; Humans; Immunodominant Epitopes; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Conformation; Protein Processing, Post-Translational; Spectroscopy, Fourier Transform Infrared; tau Proteins; Tyrosine | 1994 |
Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-tau in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Blotting, Western; Chymotrypsin; Epitopes; Humans; Microscopy, Immunoelectron; Neurofibrillary Tangles; Neurofilament Proteins; Peptide Fragments; Peptide Mapping; Phosphotyrosine; tau Proteins; Trypsin; Tyrosine; Ubiquitins | 1993 |
Drastic reduction of the zinc- and magnesium-stimulated protein tyrosine kinase activities in Alzheimer's disease hippocampus.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Female; Hippocampus; Humans; Magnesium; Male; Middle Aged; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Tyrosine; Zinc | 1993 |
p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons.
Topics: Alzheimer Disease; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Antibody Technique; Hippocampus; Humans; Microinjections; Microtubules; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Phosphotyrosine; Pregnancy; Rats; tau Proteins; Tyrosine | 1993 |
The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; DNA, Complementary; Humans; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; PC12 Cells; Phosphotyrosine; Protein Binding; Rats; Sequence Homology, Amino Acid; src Homology Domains | 1995 |
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.
Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Binding Sites; Brain; Cell Line; Friedreich Ataxia; Genetic Vectors; Humans; Kidney; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phosphotyrosine; Proto-Oncogene Proteins c-myc; Recombinant Proteins; src Homology Domains; Transfection | 1996 |
Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Binding Sites; COS Cells; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; PC12 Cells; Phosphorylation; Phosphotyrosine; Point Mutation; Precipitin Tests; Protein Binding; Proteins; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1997 |
Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor prote
Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Chromosome Mapping; Humans; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nuclear Proteins; Phosphotyrosine; Protein Binding | 1998 |
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Binding Sites; Cell Line; Cloning, Molecular; Culture Media, Conditioned; Endopeptidases; Gene Expression; Humans; Kidney; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Phosphotyrosine; Protein Processing, Post-Translational; Sequence Analysis, DNA | 1998 |
Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain.
Topics: Adolescent; Adult; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Antibodies; Blotting, Western; Densitometry; Down Syndrome; Female; Humans; Male; Middle Aged; Peptide Fragments; Phosphotyrosine; Pyrrolidonecarboxylic Acid; Tyrosine | 2001 |
c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK.
Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amino Acid Motifs; Amino Acid Substitution; Amyloid beta-Protein Precursor; Animals; Brain; Carrier Proteins; Gene Library; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Nuclear Proteins; Phosphotyrosine; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Trans-Activators; Two-Hybrid System Techniques | 2001 |
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.
Topics: Alzheimer Disease; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Chromatography, Ion Exchange; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Reference Values; Substrate Specificity; Swine; tau Proteins; Tyrosine | 1992 |
Altered protein tyrosine phosphorylation in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Blotting, Western; Humans; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1991 |
Tyrosine phosphorylation systems in Alzheimer's disease pathology.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Hippocampus; Humans; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Tyrosine | 1991 |