Page last updated: 2024-10-15

phosphoserine and Status Epilepticus

phosphoserine has been researched along with Status Epilepticus in 3 studies

Phosphoserine: The phosphoric acid ester of serine.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
"Recently, several groups reported that seizures increase mammalian target of rapamycin (mTOR) kinase activity, and such increased activity in genetic models can contribute to spontaneous seizures."5.39Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment. ( Blazejczyk, M; Caban, B; Jaworski, J; Kazmierska, P; Konopacki, J; Macias, M; Rodo, A; Skalecka, A; Tarkowski, B, 2013)
"Recently, several groups reported that seizures increase mammalian target of rapamycin (mTOR) kinase activity, and such increased activity in genetic models can contribute to spontaneous seizures."1.39Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment. ( Blazejczyk, M; Caban, B; Jaworski, J; Kazmierska, P; Konopacki, J; Macias, M; Rodo, A; Skalecka, A; Tarkowski, B, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Kim, JE1
Park, H1
Lee, JE1
Kang, TC1
Macias, M1
Blazejczyk, M1
Kazmierska, P1
Caban, B1
Skalecka, A1
Tarkowski, B1
Rodo, A1
Konopacki, J1
Jaworski, J1
Silayeva, L1
Deeb, TZ1
Hines, RM1
Kelley, MR1
Munoz, MB1
Lee, HH1
Brandon, NJ1
Dunlop, J1
Maguire, J1
Davies, PA1
Moss, SJ1

Other Studies

3 other studies available for phosphoserine and Status Epilepticus

ArticleYear
CDDO-Me Inhibits Microglial Activation and Monocyte Infiltration by Abrogating NFκB- and p38 MAPK-Mediated Signaling Pathways Following Status Epilepticus.
    Cells, 2020, 05-01, Volume: 9, Issue:5

    Topics: Animals; Chemokine CCL2; Frontal Lobe; Male; MAP Kinase Signaling System; Microglia; Models, Biologi

2020
Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Astrocytes; Brain; Cell Death; Cell Nucleus; Hippocampus; Kainic Acid; Male; Neurons; Phosp

2013
KCC2 activity is critical in limiting the onset and severity of status epilepticus.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-17, Volume: 112, Issue:11

    Topics: Animals; Chlorides; Endocytosis; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Glutamates; K Cl

2015