phosphoserine has been researched along with Obesity in 13 studies
Phosphoserine: The phosphoric acid ester of serine.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity is accompanied by impaired fasting glycerol release, lower HSL protein expression, and serine phosphorylation." | 3.74 | Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation. ( Blaak, EE; Goossens, GH; Jocken, JW; Kiens, B; Roepstorff, C; Saris, WH; van Baak, M; van der Baan, P, 2008) |
| "Obesity is defined as an abnormal accumulation of adipose tissue, which is one of the major metabolic organs that regulate energy homeostasis." | 2.72 | Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential. ( Han, J; Im, H; Im, S; Kim, K; Lee, YH; Park, JH, 2021) |
| "Obesity is accompanied by impaired fasting glycerol release, lower HSL protein expression, and serine phosphorylation." | 1.35 | Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation. ( Blaak, EE; Goossens, GH; Jocken, JW; Kiens, B; Roepstorff, C; Saris, WH; van Baak, M; van der Baan, P, 2008) |
| "Obesity is associated with insulin resistance and a state of abnormal inflammatory response." | 1.34 | Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. ( Araújo, EP; Carvalheira, JB; Carvalho-Filho, MA; Curi, R; Hirabara, SM; Prada, PO; Saad, MJ; Schenka, AA; Tsukumo, DM; Vassallo, J; Velloso, LA, 2007) |
| "We conclude that obesity is associated with increased intramyocellular ceramide content." | 1.32 | Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. ( Adams, JM; Berria, R; DeFronzo, RA; Mandarino, LJ; Pratipanawatr, T; Sullards, MC; Wang, E, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bukosza, EN | 1 |
| Kaucsár, T | 1 |
| Godó, M | 1 |
| Lajtár, E | 1 |
| Tod, P | 1 |
| Koncsos, G | 1 |
| Varga, ZV | 1 |
| Baranyai, T | 1 |
| Nguyen, MT | 1 |
| Schachner, H | 1 |
| Sőti, C | 1 |
| Ferdinandy, P | 1 |
| Giricz, Z | 1 |
| Szénási, G | 1 |
| Hamar, P | 1 |
| Im, H | 1 |
| Park, JH | 1 |
| Im, S | 1 |
| Han, J | 1 |
| Kim, K | 1 |
| Lee, YH | 1 |
| Kim, B | 1 |
| Figueroa-Romero, C | 1 |
| Pacut, C | 1 |
| Backus, C | 1 |
| Feldman, EL | 1 |
| Choi, JH | 2 |
| Banks, AS | 2 |
| Estall, JL | 1 |
| Kajimura, S | 1 |
| Boström, P | 1 |
| Laznik, D | 2 |
| Ruas, JL | 1 |
| Chalmers, MJ | 2 |
| Kamenecka, TM | 2 |
| Blüher, M | 1 |
| Griffin, PR | 2 |
| Spiegelman, BM | 2 |
| Busby, SA | 1 |
| Kumar, N | 1 |
| Kuruvilla, DS | 1 |
| Shin, Y | 1 |
| He, Y | 1 |
| Bruning, JB | 1 |
| Marciano, DP | 1 |
| Cameron, MD | 1 |
| Jurczak, MJ | 1 |
| Schürer, SC | 1 |
| Vidović, D | 1 |
| Shulman, GI | 1 |
| Jiang, G | 1 |
| Dallas-Yang, Q | 1 |
| Li, Z | 1 |
| Szalkowski, D | 1 |
| Liu, F | 1 |
| Shen, X | 1 |
| Wu, M | 1 |
| Zhou, G | 1 |
| Doebber, T | 1 |
| Berger, J | 1 |
| Moller, DE | 1 |
| Zhang, BB | 1 |
| Carvalheira, JB | 2 |
| Ribeiro, EB | 1 |
| Araújo, EP | 2 |
| Guimarães, RB | 1 |
| Telles, MM | 1 |
| Torsoni, M | 1 |
| Gontijo, JA | 1 |
| Velloso, LA | 2 |
| Saad, MJ | 2 |
| Adams, JM | 1 |
| Pratipanawatr, T | 1 |
| Berria, R | 1 |
| Wang, E | 1 |
| DeFronzo, RA | 1 |
| Sullards, MC | 1 |
| Mandarino, LJ | 1 |
| Gao, Z | 1 |
| Zhang, X | 1 |
| Zuberi, A | 1 |
| Hwang, D | 1 |
| Quon, MJ | 1 |
| Lefevre, M | 1 |
| Ye, J | 1 |
| Tsukumo, DM | 1 |
| Carvalho-Filho, MA | 1 |
| Prada, PO | 1 |
| Hirabara, SM | 1 |
| Schenka, AA | 1 |
| Vassallo, J | 1 |
| Curi, R | 1 |
| Hosooka, T | 1 |
| Noguchi, T | 1 |
| Kotani, K | 1 |
| Nakamura, T | 1 |
| Sakaue, H | 1 |
| Inoue, H | 1 |
| Ogawa, W | 1 |
| Tobimatsu, K | 1 |
| Takazawa, K | 1 |
| Sakai, M | 1 |
| Matsuki, Y | 1 |
| Hiramatsu, R | 1 |
| Yasuda, T | 1 |
| Lazar, MA | 1 |
| Yamanashi, Y | 1 |
| Kasuga, M | 1 |
| Jocken, JW | 1 |
| Roepstorff, C | 1 |
| Goossens, GH | 1 |
| van der Baan, P | 1 |
| van Baak, M | 1 |
| Saris, WH | 1 |
| Kiens, B | 1 |
| Blaak, EE | 1 |
| Dunaif, A | 1 |
| Xia, J | 1 |
| Book, CB | 1 |
| Schenker, E | 1 |
| Tang, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Muscle Insulin Resistance In Aging[NCT02230839] | 200 participants (Anticipated) | Interventional | 2014-06-30 | Active, not recruiting | |||
| Regulation of Lipolysis by Insulin in Skeletal Muscle and Adipose Tissue in Type 2 Diabetes[NCT01680133] | 20 participants (Actual) | Observational | 2007-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phosphoserine and Obesity
| Article | Year |
|---|---|
Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Energy Metabolism; Humans; Metabolic Diseases; Obesi | 2021 |
12 other studies available for phosphoserine and Obesity
| Article | Year |
|---|---|
Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats.
Topics: Adipose Tissue; Animals; Biomarkers; Body Weight; Collagen; Diet, High-Fat; Fibrosis; Gene Expressio | 2019 |
Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485 Phosphorylation.
Topics: Adenylate Kinase; Alzheimer Disease; Animals; Cell Line; Diabetes Complications; Diet, High-Fat; Hum | 2015 |
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
Topics: Adipose Tissue; Amino Acid Sequence; Animals; Cell Line; Cyclin-Dependent Kinase 5; Diabetes Mellitu | 2010 |
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Biphenyl Compounds; Body Fluids; Chloroceb | 2011 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Pro | 2002 |
Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats.
Topics: Animals; Blood Glucose; Body Weight; Hypothalamus; Injections, Intraventricular; Insulin; Insulin Re | 2003 |
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.
Topics: Adult; Blood Glucose; Ceramides; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Humans | 2004 |
Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.
Topics: Adipocytes; Adipose Tissue; Animal Feed; Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; F | 2004 |
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.
Topics: Adipose Tissue; Animal Feed; Animals; Blood Glucose; Body Weight; Cell Shape; Dietary Fats; Enzyme A | 2007 |
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.
Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Adiposity; Animals; Diet; DNA-Binding Proteins; Ext | 2008 |
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Body Mass Index; Glycerol; Humans; Isoproterenol; K | 2008 |
Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome.
Topics: Adult; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Fibroblasts; Humans; Insul | 1995 |