Page last updated: 2024-10-15

phosphoserine and Nerve Degeneration

phosphoserine has been researched along with Nerve Degeneration in 13 studies

Phosphoserine: The phosphoric acid ester of serine.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"In vivo, a middle cerebral artery occlusion/reperfusion (MCAO/R) model in adult male Sprague Dawley rats (250-300 g) was established, and in vitro, cultured primary neurons were subjected to oxygen-glucose deprivation/reoxygenation (OGD/R) to imitate I/R injury."1.62Phosphorylation at S548 as a Functional Switch of Sterile Alpha and TIR Motif-Containing 1 in Cerebral Ischemia/Reperfusion Injury in Rats. ( Chen, G; Li, H; Li, X; Shen, H; Sun, Q; Wang, Z; Wu, J; Wu, X; Xue, T; Zhang, Y, 2021)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Xue, T1
Sun, Q1
Zhang, Y1
Wu, X1
Shen, H1
Li, X1
Wu, J1
Li, H1
Wang, Z1
Chen, G1
Zhang, S1
Liu, YQ1
Jia, C1
Lim, YJ1
Feng, G1
Xu, E1
Long, H1
Kimura, Y1
Tao, Y1
Zhao, C1
Wang, C1
Liu, Z2
Hu, JJ1
Ma, MR1
Jiang, L1
Li, D1
Wang, R1
Dawson, VL1
Dawson, TM1
Li, YM1
Mao, X1
Liu, C1
Van Rompuy, AS1
Oliveras-Salvá, M1
Van der Perren, A1
Corti, O1
Van den Haute, C1
Baekelandt, V1
Zhuang, N1
Li, L1
Chen, S1
Wang, T1
Mukerjee, R1
Deshmane, SL1
Fan, S1
Del Valle, L1
White, MK1
Khalili, K1
Amini, S1
Sawaya, BE1
Iijima-Ando, K2
Zhao, L1
Gatt, A2
Shenton, C1
Iijima, K2
Ksiezak-Reding, H1
Pyo, HK1
Feinstein, B1
Pasinetti, GM1
Klumpp, S1
Thissen, MC1
Krieglstein, J1
Copani, A1
Bruno, V1
Battaglia, G1
Leanza, G1
Pellitteri, R1
Russo, A1
Stanzani, S1
Nicoletti, F1
Price, MT1
Romano, C1
Fix, AS1
Tizzano, JP1
Olney, JW1
Shiurba, RA1
Ishiguro, K1
Takahashi, M1
Sato, K1
Spooner, ET1
Mercken, M1
Yoshida, R1
Wheelock, TR1
Yanagawa, H1
Imahori, K1
Nixon, RA1
Oh, JD1
Vaughan, CL1
Chase, TN1

Reviews

1 review available for phosphoserine and Nerve Degeneration

ArticleYear
Protein phosphatases types 2Calpha and 2Cbeta in apoptosis.
    Biochemical Society transactions, 2006, Volume: 34, Issue:Pt 6

    Topics: Animals; Apoptosis; Cell Survival; Enzyme Activation; Fatty Acids, Nonesterified; Fatty Acids, Unsat

2006

Other Studies

12 other studies available for phosphoserine and Nerve Degeneration

ArticleYear
Phosphorylation at S548 as a Functional Switch of Sterile Alpha and TIR Motif-Containing 1 in Cerebral Ischemia/Reperfusion Injury in Rats.
    Molecular neurobiology, 2021, Volume: 58, Issue:2

    Topics: Animals; Armadillo Domain Proteins; Axons; Brain Ischemia; Cells, Cultured; Cytoskeletal Proteins; I

2021
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-29, Volume: 118, Issue:26

    Topics: alpha-Synuclein; Amyloid; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Cell Line, Tumor; E

2021
Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.
    Molecular neurodegeneration, 2015, 06-23, Volume: 10

    Topics: alpha-Synuclein; Animals; Cell Count; Cell Line, Tumor; Dependovirus; Dopaminergic Neurons; Female;

2015
PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control.
    Cell death & disease, 2016, 12-01, Volume: 7, Issue:12

    Topics: Amino Acid Sequence; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins;

2016
Involvement of the p53 and p73 transcription factors in neuroAIDS.
    Cell cycle (Georgetown, Tex.), 2008, Sep-01, Volume: 7, Issue:17

    Topics: AIDS Dementia Complex; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cell Line, Tumor; DNA-Bindin

2008
A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration.
    Human molecular genetics, 2010, May-15, Volume: 19, Issue:10

    Topics: Animals; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; Drosophila melanogaster; Enzyme Activ

2010
Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.
    Human molecular genetics, 2010, Aug-01, Volume: 19, Issue:15

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Brain; Checkpoint

2010
Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro.
    Biochimica et biophysica acta, 2003, Nov-20, Volume: 1639, Issue:3

    Topics: Alzheimer Disease; Amino Acid Sequence; Biomarkers; Cloning, Molecular; Consensus Sequence; Escheric

2003
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.
    Molecular pharmacology, 1995, Volume: 47, Issue:5

    Topics: Aminobutyrates; Amyloid beta-Peptides; Animals; Apoptosis; Benzoates; Calcium Channels; Cells, Cultu

1995
Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents.
    Neuropharmacology, 1995, Volume: 34, Issue:8

    Topics: Alanine; Animals; Animals, Newborn; Asparagine; Brain Diseases; Excitatory Amino Acid Antagonists; I

1995
Immunocytochemistry of tau phosphoserine 413 and tau protein kinase I in Alzheimer pathology.
    Brain research, 1996, Oct-21, Volume: 737, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Antibody Specificity; Brain;

1996
Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal NMDA receptor subunits.
    Brain research, 1999, Mar-13, Volume: 821, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Antiparkinson Agent

1999