phosphoserine has been researched along with Multiple System Atrophy in 1 studies
Phosphoserine: The phosphoric acid ester of serine.
Multiple System Atrophy: A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast to Parkinson's disease (PD) where the pathological α-syn aggregates are almost exclusively neuronal, the α-syn inclusions in MSA are principally observed in oligodendrocytes (OLs) where they form glial cytoplasmic inclusions (GCIs)." | 1.56 | Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy. ( Bezard, E; De Giorgi, F; Doudnikoff, E; Faggiani, E; He, X; Ichas, F; Laferrière, F; Meissner, WG; Zinghirino, F, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laferrière, F | 1 |
| He, X | 1 |
| Zinghirino, F | 1 |
| Doudnikoff, E | 1 |
| Faggiani, E | 1 |
| Meissner, WG | 1 |
| Bezard, E | 1 |
| De Giorgi, F | 1 |
| Ichas, F | 1 |
1 other study available for phosphoserine and Multiple System Atrophy
| Article | Year |
|---|---|
Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy.
Topics: alpha-Synuclein; Amyloid; Animals; Brain; Cells, Cultured; Humans; Mice, Inbred C57BL; Mice, Transge | 2020 |