phosphoserine has been researched along with Disease Models, Animal in 52 studies
Phosphoserine: The phosphoric acid ester of serine.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Various evidences have documented that the pineal secretory product melatonin exerts an important anti-inflammatory effect in different experimental models including colitis." | 7.73 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "The potential anticonvulsant effect of group III metabotropic glutamate receptor (mGluR) agonist (R,S)-4-phosphonophenylglycine ((R,S)-PPG) against seizures induced in immature 12-day-old rats by bilateral intracerebroventricular (icv) infusion of DL-homocysteic acid (DL-HCA, 600 nmol/side) was examined in the present study." | 7.72 | Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine. ( Folbergrová, J; Haugvicová, R; Mares, P, 2003) |
| "Treatment with melatonin (15 mg/kg daily i." | 5.33 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "Colitis was induced by intracolonic instillation of dinitrobenzene sulfonic acid (DNBS)." | 5.33 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "Generalized clonic-tonic seizures were completely suppressed and cortical energy metabolite changes which normally accompany these seizures were either normalized (glucose and glycogen decreases) or markedly ameliorated (an accumulation of lactate)." | 5.32 | Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine. ( Folbergrová, J; Haugvicová, R; Mares, P, 2003) |
| " Effects of intrathecal glutamate transporter activator (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline and inhibitors (DL-threo-β-benzyloxyaspartate [TBOA], dihydrokainate, and DL-threo-β-hydroxyaspartate), or TBOA plus group III metabotropic glutamate receptor antagonist (RS)-α-methylserine-O-phosphate, on formalin- and CFA-induced inflammatory pain were examined." | 3.77 | Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant. ( Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M, 2011) |
| "In this study, the effect of (S)-3,4-dicarboxyphenylglycine (DCPG), a selective mGlu8 receptor agonist, has been investigated in inflammatory and neuropathic pain models in order to elucidate the role of mGlu8 receptor in modulating pain perception." | 3.74 | Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice. ( de Novellis, V; Maione, S; Marabese, I; Palazzo, E; Rossi, F; Scafuro, MA; Vita, D, 2007) |
| "Various evidences have documented that the pineal secretory product melatonin exerts an important anti-inflammatory effect in different experimental models including colitis." | 3.73 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "The potential anticonvulsant effect of group III metabotropic glutamate receptor (mGluR) agonist (R,S)-4-phosphonophenylglycine ((R,S)-PPG) against seizures induced in immature 12-day-old rats by bilateral intracerebroventricular (icv) infusion of DL-homocysteic acid (DL-HCA, 600 nmol/side) was examined in the present study." | 3.72 | Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine. ( Folbergrová, J; Haugvicová, R; Mares, P, 2003) |
| "Heritable nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentration mechanisms in the kidney, which are mainly caused by loss-of-function mutations in the vasopressin type 2 receptor." | 1.43 | Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway. ( Ando, F; Kikuchi, E; Kondo, Y; Mori, T; Morimoto, T; Nomura, N; Rai, T; Sasaki, S; Sohara, E; Takahashi, D; Uchida, S; Vandewalle, A; Yui, N, 2016) |
| "Conversely, Tnfr1(-/-)Tag-expressing cancers resist cytokine-induced senescence and grow aggressively, even in TNFR1-expressing hosts." | 1.39 | T-helper-1-cell cytokines drive cancer into senescence. ( Alkhaled, M; Aßmann, S; Bauer, J; Berdel, J; Braumüller, H; Braungart, K; Brenner, E; Essmann, F; Fehrenbacher, B; Fend, F; Griessinger, C; Hahn, M; Handgretinger, R; Häring, HU; Kneilling, M; Mehra, T; Meier, F; Mocikat, R; Niessner, H; Pesic, M; Quintanilla-Martinez, L; Ranta, F; Röcken, M; Schaller, M; Schilbach, K; Schulze-Osthoff, K; Ullrich, S; van den Broek, M; Wieder, T; Zender, L, 2013) |
| "The mechanisms of Src implication in cancer and inflammation are linked to the ability of activated Src to phosphorylate multiple downstream targets that mediate its cellular effector functions." | 1.36 | Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells. ( Abdel Fattah, E; Eissa, NT; Gorgun, FM; Mazumdar, T; Pandit, L; Tyryshkin, A; Zeng, S, 2010) |
| "Hemostasis and thrombosis are regulated by agonist-induced activation of platelet integrin alpha(IIb)beta(3)." | 1.35 | The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function. ( Alrehani, N; Cruz, MA; Gushiken, FC; Hyojeong, H; Langlois, KW; Pradhan, S; Rumbaut, RE; Vijayan, KV, 2009) |
| "Accordingly, type 2 diabetes characterized by insulin resistance is associated with an increased risk of developing Alzheimer's disease." | 1.33 | Peripheral hyperinsulinemia promotes tau phosphorylation in vivo. ( Bruning, JC; Freude, S; Krone, W; Leeser, U; Plum, L; Schnitker, J; Schubert, M; Udelhoven, M, 2005) |
| "Treatment with melatonin (15 mg/kg daily i." | 1.33 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "Colitis was induced by intracolonic instillation of dinitrobenzene sulfonic acid (DNBS)." | 1.33 | Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. ( Crisafulli, C; Cuzzocrea, S; Di Bella, P; Esposito, E; Mazzon, E; Meli, R; Muià, C; Riccardi, L, 2006) |
| "Generalized clonic-tonic seizures were completely suppressed and cortical energy metabolite changes which normally accompany these seizures were either normalized (glucose and glycogen decreases) or markedly ameliorated (an accumulation of lactate)." | 1.32 | Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine. ( Folbergrová, J; Haugvicová, R; Mares, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.92) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (23.08) | 29.6817 |
| 2010's | 35 (67.31) | 24.3611 |
| 2020's | 4 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Yuan, J | 1 |
| Yu, X | 2 |
| Liu, X | 1 |
| Tan, C | 1 |
| Chen, Y | 1 |
| Xu, T | 1 |
| Foote, KM | 1 |
| Lyman, KA | 1 |
| Han, Y | 1 |
| Michailidis, IE | 1 |
| Heuermann, RJ | 1 |
| Mandikian, D | 1 |
| Trimmer, JS | 1 |
| Swanson, GT | 1 |
| Chetkovich, DM | 1 |
| Kumari, R | 1 |
| Kumar, R | 1 |
| Kumar, S | 1 |
| Singh, AK | 1 |
| Hanpude, P | 1 |
| Jangir, D | 1 |
| Maiti, TK | 1 |
| Muñoz-Lasso, DC | 1 |
| Mollá, B | 1 |
| Calap-Quintana, P | 1 |
| García-Giménez, JL | 1 |
| Pallardo, FV | 1 |
| Palau, F | 1 |
| Gonzalez-Cabo, P | 1 |
| Martín-Flores, N | 1 |
| Pérez-Sisqués, L | 1 |
| Creus-Muncunill, J | 1 |
| Masana, M | 1 |
| Ginés, S | 2 |
| Alberch, J | 1 |
| Pérez-Navarro, E | 1 |
| Malagelada, C | 1 |
| Zhou, J | 1 |
| Tien, AC | 1 |
| Alberta, JA | 1 |
| Ficarro, SB | 1 |
| Griveau, A | 1 |
| Sun, Y | 1 |
| Deshpande, JS | 1 |
| Card, JD | 1 |
| Morgan-Smith, M | 1 |
| Michowski, W | 1 |
| Hashizume, R | 1 |
| James, CD | 1 |
| Ligon, KL | 1 |
| Snider, WD | 1 |
| Sicinski, P | 1 |
| Marto, JA | 1 |
| Rowitch, DH | 1 |
| Stiles, CD | 1 |
| Daldin, M | 1 |
| Fodale, V | 1 |
| Cariulo, C | 1 |
| Azzollini, L | 1 |
| Verani, M | 1 |
| Martufi, P | 1 |
| Spiezia, MC | 1 |
| Deguire, SM | 1 |
| Cherubini, M | 1 |
| Macdonald, D | 1 |
| Weiss, A | 1 |
| Bresciani, A | 1 |
| Vonsattel, JG | 1 |
| Petricca, L | 1 |
| Marsh, JL | 1 |
| Santimone, I | 1 |
| Marano, M | 1 |
| Lashuel, HA | 1 |
| Squitieri, F | 1 |
| Caricasole, A | 1 |
| Ranieri, A | 1 |
| Kemp, E | 1 |
| Burgoyne, JR | 1 |
| Avkiran, M | 1 |
| Kurano, M | 1 |
| Tsuneyama, K | 1 |
| Morimoto, Y | 1 |
| Shimizu, T | 1 |
| Jona, M | 1 |
| Kassai, H | 1 |
| Nakao, K | 1 |
| Aiba, A | 1 |
| Yatomi, Y | 1 |
| Chen, J | 1 |
| Ren, Y | 1 |
| Gui, C | 1 |
| Zhao, M | 1 |
| Wu, X | 1 |
| Mao, K | 1 |
| Li, W | 1 |
| Zou, F | 1 |
| Kawa, Y | 1 |
| Nagano, T | 1 |
| Yoshizaki, A | 1 |
| Dokuni, R | 1 |
| Katsurada, M | 1 |
| Terashita, T | 1 |
| Yasuda, Y | 1 |
| Umezawa, K | 1 |
| Yamamoto, M | 1 |
| Kamiryo, H | 1 |
| Kobayashi, K | 1 |
| Nishimura, Y | 1 |
| Ma, C | 1 |
| Tian, X | 1 |
| Kim, JP | 1 |
| Xie, D | 1 |
| Ao, X | 1 |
| Shan, D | 1 |
| Lin, Q | 1 |
| Hudock, MR | 1 |
| Bai, X | 1 |
| Yang, J | 1 |
| Cavallucci, V | 1 |
| Berretta, N | 1 |
| Nobili, A | 1 |
| Nisticò, R | 1 |
| Mercuri, NB | 1 |
| D'Amelio, M | 1 |
| Contín, MA | 1 |
| Arietti, MM | 1 |
| Benedetto, MM | 1 |
| Bussi, C | 1 |
| Guido, ME | 1 |
| Fathallah, AM | 1 |
| Ramakrishnan, R | 1 |
| Balu-Iyer, SV | 2 |
| Ozmen, L | 1 |
| Collin, L | 1 |
| Liu, SB | 1 |
| Zhang, MM | 1 |
| Cheng, LF | 1 |
| Shi, J | 1 |
| Lu, JS | 1 |
| Zhuo, M | 1 |
| Ando, K | 1 |
| Oka, M | 1 |
| Ohtake, Y | 1 |
| Hayashishita, M | 1 |
| Shimizu, S | 1 |
| Hisanaga, S | 1 |
| Iijima, KM | 1 |
| Hasegawa, Y | 1 |
| Uekawa, K | 1 |
| Kawano, T | 1 |
| Suzuki, H | 1 |
| Kim-Mitsuyama, S | 1 |
| Dai, X | 1 |
| Ding, Y | 1 |
| Liu, Z | 1 |
| Zhang, W | 1 |
| Zou, MH | 1 |
| Ando, F | 1 |
| Sohara, E | 1 |
| Morimoto, T | 1 |
| Yui, N | 1 |
| Nomura, N | 1 |
| Kikuchi, E | 1 |
| Takahashi, D | 1 |
| Mori, T | 1 |
| Vandewalle, A | 1 |
| Rai, T | 1 |
| Sasaki, S | 1 |
| Kondo, Y | 1 |
| Uchida, S | 1 |
| Zhuang, N | 1 |
| Li, L | 1 |
| Chen, S | 1 |
| Wang, T | 1 |
| Ye, Y | 1 |
| Zhao, Z | 1 |
| Xu, H | 2 |
| Zhang, X | 1 |
| Su, X | 1 |
| Yang, Y | 1 |
| He, X | 1 |
| Dolan, S | 1 |
| Gunn, MD | 1 |
| Biddlestone, L | 1 |
| Nolan, AM | 1 |
| Tyryshkin, A | 1 |
| Gorgun, FM | 1 |
| Abdel Fattah, E | 1 |
| Mazumdar, T | 1 |
| Pandit, L | 1 |
| Zeng, S | 1 |
| Eissa, NT | 1 |
| Gushiken, FC | 1 |
| Hyojeong, H | 1 |
| Pradhan, S | 1 |
| Langlois, KW | 1 |
| Alrehani, N | 1 |
| Cruz, MA | 1 |
| Rumbaut, RE | 1 |
| Vijayan, KV | 1 |
| Iijima, K | 1 |
| Gatt, A | 1 |
| Iijima-Ando, K | 1 |
| Xin-Long, C | 1 |
| Zhao-Fan, X | 1 |
| Dao-Feng, B | 1 |
| Wei, D | 1 |
| Austin, PJ | 1 |
| Betts, MJ | 1 |
| Broadstock, M | 1 |
| O'Neill, MJ | 1 |
| Mitchell, SN | 1 |
| Duty, S | 1 |
| Sofola, O | 1 |
| Kerr, F | 1 |
| Rogers, I | 1 |
| Killick, R | 1 |
| Augustin, H | 1 |
| Gandy, C | 1 |
| Allen, MJ | 1 |
| Hardy, J | 1 |
| Lovestone, S | 1 |
| Partridge, L | 1 |
| Yaster, M | 1 |
| Guan, X | 1 |
| Petralia, RS | 1 |
| Rothstein, JD | 1 |
| Lu, W | 1 |
| Tao, YX | 1 |
| Beurel, E | 1 |
| Song, L | 1 |
| Jope, RS | 1 |
| Roy, D | 1 |
| Dittmer, DP | 1 |
| Choi, JH | 1 |
| Banks, AS | 1 |
| Kamenecka, TM | 1 |
| Busby, SA | 1 |
| Chalmers, MJ | 1 |
| Kumar, N | 1 |
| Kuruvilla, DS | 1 |
| Shin, Y | 1 |
| He, Y | 1 |
| Bruning, JB | 1 |
| Marciano, DP | 1 |
| Cameron, MD | 1 |
| Laznik, D | 1 |
| Jurczak, MJ | 1 |
| Schürer, SC | 1 |
| Vidović, D | 1 |
| Shulman, GI | 1 |
| Spiegelman, BM | 1 |
| Griffin, PR | 1 |
| Coffee, RL | 1 |
| Williamson, AJ | 1 |
| Adkins, CM | 1 |
| Gray, MC | 1 |
| Page, TL | 1 |
| Broadie, K | 1 |
| Wang, P | 1 |
| Guan, YF | 1 |
| Du, H | 1 |
| Zhai, QW | 1 |
| Su, DF | 1 |
| Miao, CY | 1 |
| Vera, G | 1 |
| Tapia, R | 1 |
| Di Pardo, A | 1 |
| Maglione, V | 1 |
| Alpaugh, M | 1 |
| Horkey, M | 1 |
| Atwal, RS | 1 |
| Sassone, J | 1 |
| Ciammola, A | 1 |
| Steffan, JS | 1 |
| Fouad, K | 1 |
| Truant, R | 1 |
| Sipione, S | 1 |
| Duran, JM | 1 |
| Taghavi, S | 1 |
| Berretta, RM | 1 |
| Makarewich, CA | 1 |
| Sharp Iii, T | 1 |
| Starosta, T | 1 |
| Udeshi, F | 1 |
| George, JC | 1 |
| Kubo, H | 1 |
| Houser, SR | 1 |
| Krolikowski, JG | 1 |
| Jones, DW | 1 |
| Ge, ZD | 1 |
| Pagel, PS | 1 |
| Pritchard, KA | 1 |
| Weihrauch, D | 1 |
| Braumüller, H | 1 |
| Wieder, T | 1 |
| Brenner, E | 1 |
| Aßmann, S | 1 |
| Hahn, M | 1 |
| Alkhaled, M | 1 |
| Schilbach, K | 1 |
| Essmann, F | 1 |
| Kneilling, M | 1 |
| Griessinger, C | 1 |
| Ranta, F | 1 |
| Ullrich, S | 1 |
| Mocikat, R | 1 |
| Braungart, K | 1 |
| Mehra, T | 1 |
| Fehrenbacher, B | 1 |
| Berdel, J | 1 |
| Niessner, H | 1 |
| Meier, F | 1 |
| van den Broek, M | 1 |
| Häring, HU | 1 |
| Handgretinger, R | 1 |
| Quintanilla-Martinez, L | 1 |
| Fend, F | 1 |
| Pesic, M | 1 |
| Bauer, J | 1 |
| Zender, L | 1 |
| Schaller, M | 1 |
| Schulze-Osthoff, K | 1 |
| Röcken, M | 1 |
| Osuka, K | 2 |
| Watanabe, Y | 2 |
| Usuda, N | 2 |
| Nakazawa, A | 2 |
| Fukunaga, K | 1 |
| Miyamoto, E | 1 |
| Takayasu, M | 1 |
| Tokuda, M | 2 |
| Yoshida, J | 2 |
| Folbergrová, J | 1 |
| Haugvicová, R | 1 |
| Mares, P | 1 |
| Musicki, B | 1 |
| Kramer, MF | 1 |
| Becker, RE | 1 |
| Burnett, AL | 1 |
| Freude, S | 1 |
| Plum, L | 1 |
| Schnitker, J | 1 |
| Leeser, U | 1 |
| Udelhoven, M | 1 |
| Krone, W | 1 |
| Bruning, JC | 1 |
| Schubert, M | 1 |
| Yamauchi, K | 1 |
| Brunner, TB | 1 |
| Ernst-Stecken, A | 1 |
| Jeske, I | 1 |
| Grabenbauer, GG | 1 |
| Sauer, R | 1 |
| Distel, L | 1 |
| Mazzon, E | 1 |
| Esposito, E | 1 |
| Crisafulli, C | 1 |
| Riccardi, L | 1 |
| Muià, C | 1 |
| Di Bella, P | 1 |
| Meli, R | 1 |
| Cuzzocrea, S | 1 |
| Marabese, I | 1 |
| de Novellis, V | 1 |
| Palazzo, E | 1 |
| Scafuro, MA | 1 |
| Vita, D | 1 |
| Rossi, F | 1 |
| Maione, S | 1 |
| Miclea, RD | 1 |
| Purohit, VS | 1 |
| Schweigreiter, R | 1 |
| Stasyk, T | 1 |
| Contarini, I | 1 |
| Frauscher, S | 1 |
| Oertle, T | 1 |
| Klimaschewski, L | 1 |
| Huber, LA | 1 |
| Bandtlow, CE | 1 |
| Glimcher, MJ | 1 |
| Reit, B | 1 |
| Kossiva, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis[NCT02737202] | Phase 2 | 28 participants (Actual) | Interventional | 2016-04-30 | Terminated | ||
| Evaluation of the Initial Prescription of Ketamine and Milnacipran Forin Depression in Patients With a Progressive Disease[NCT02783430] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
52 other studies available for phosphoserine and Disease Models, Animal
| Article | Year |
|---|---|
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Topics: Animals; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Epilepsy; E | 2021 |
Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function.
Topics: Amino Acid Sequence; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dendrites; | 2019 |
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease.
Topics: Actin Cytoskeleton; alpha-Synuclein; Amyloid; Animals; Apoptosis; Cell Death; Cell Line, Tumor; Comp | 2020 |
Cofilin dysregulation alters actin turnover in frataxin-deficient neurons.
Topics: Actin Cytoskeleton; Actin-Related Protein 2-3 Complex; Actins; Animals; Axons; Cells, Cultured; Cofi | 2020 |
Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cells, Cultured; Cerebral Cortex; Corpus Striatum; De | 2020 |
A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.
Topics: Animals; Carcinogenesis; Casein Kinase II; Cell Line, Tumor; Cyclin-Dependent Kinases; Disease Model | 2017 |
Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.
Topics: Animals; Brain; Disease Models, Animal; Drosophila; Exons; Fibroblasts; HEK293 Cells; Humans; Huntin | 2017 |
β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573.
Topics: Adenoviridae; Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Cardiomegaly; Disease Models, | 2018 |
Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury.
Topics: Alanine Transaminase; Animals; Apolipoproteins M; Clustered Regularly Interspaced Short Palindromic | 2018 |
Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Apoptosis; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Enzyme | 2018 |
Role of S1P/S1PR3 axis in release of CCL20 from human bronchial epithelial cells.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchi; Cell Line; Chemokine CCL20; Disease Models, Anim | 2018 |
Citrate-based materials fuel human stem cells by metabonegenic regulation.
Topics: Adenosine Triphosphate; Animals; Biocompatible Materials; Biopolymers; Bone Regeneration; Cell Adhes | 2018 |
Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; CA1 Region, Hippocampal; Calcineurin Inhibitors; Caspase 3; Dendrites; D | 2013 |
Photoreceptor damage induced by low-intensity light: model of retinal degeneration in mammals.
Topics: Animals; Annexin A5; Caspase 3; Cell Death; Disease Models, Animal; In Situ Nick-End Labeling; Light | 2013 |
O-phospho-l-serine mediates hyporesponsiveness toward FVIII in hemophilia A-murine model by inducing tolerogenic properties in dendritic cells.
Topics: Adjuvants, Immunologic; Animals; Antibodies; CD40 Antigens; Cells, Cultured; Coagulants; Dendritic C | 2014 |
[Passive Tau immunotherapy for prevention of Tau pathology progression].
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Disease Models, Animal; Disease Progression; | 2015 |
Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.
Topics: Adamantane; Adenylyl Cyclases; Animals; Behavior, Animal; Calcium; Cell Membrane; Chronic Pain; Dise | 2015 |
Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.
Topics: Alzheimer Disease; Amino Acid Substitution; Animals; Disease Models, Animal; Drosophila melanogaster | 2016 |
Blockage of Central Sphingosine-1-phosphate Receptor does not Abolish the Protective Effect of FTY720 in Early Brain Injury after Experimental Subarachnoid Hemorrhage.
Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Fingolimod Hydrochloride; Male; Neuroprotective | 2017 |
Phosphorylation of CHOP (C/EBP Homologous Protein) by the AMP-Activated Protein Kinase Alpha 1 in Macrophages Promotes CHOP Degradation and Reduces Injury-Induced Neointimal Disruption In Vivo.
Topics: AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Apoptosis; Carotid Artery, Common; Caroti | 2016 |
Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway.
Topics: Animals; Aquaporin 2; Arachidonic Acid; beta Catenin; Calcineurin; Calcium; Calcium Signaling; Cycli | 2016 |
PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control.
Topics: Amino Acid Sequence; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; | 2016 |
Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Hippocampus; Male; MAP Kinase Signaling | 2016 |
The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat.
Topics: Allosteric Regulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzhydryl Compounds; Carra | 2009 |
Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Epidermal Gr | 2010 |
The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.
Topics: Animals; Blood Platelets; Catalytic Domain; Disease Models, Animal; Fibrinogen; Glycogen Synthase Ki | 2009 |
Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Brain; Checkpoint | 2010 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Burns; C-Peptide; Disease Models, Animal; Glucose | 2011 |
Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease.
Topics: Aminobutyrates; Animals; Aspartic Acid; Disease Models, Animal; Excitatory Amino Acid Agonists; Glut | 2010 |
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Drosophil | 2010 |
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; | 2011 |
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice.
Topics: Amino Acid Substitution; Animals; Antidepressive Agents; Cerebral Cortex; Depression; Disease Models | 2011 |
Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma.
Topics: Animals; Biopsy; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Enzyme Activation; Hu | 2011 |
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Biphenyl Compounds; Body Fluids; Chloroceb | 2011 |
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.
Topics: Animals; Animals, Genetically Modified; Brain; Cytoskeleton; Disease Models, Animal; Drosophila mela | 2012 |
Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia.
Topics: Adenine; Animals; Autophagy; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Glucose; Infar | 2012 |
Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo.
Topics: 4-Aminopyridine; Amino Acids; Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Disea | 2012 |
Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.
Topics: Animals; Codon; Corpus Striatum; Dimerization; Disease Models, Animal; Dopamine and cAMP-Regulated P | 2012 |
A characterization and targeting of the infarct border zone in a swine model of myocardial infarction.
Topics: Animals; Biomechanical Phenomena; Blotting, Western; Disease Models, Animal; Echocardiography; Fluor | 2012 |
4F decreases IRF5 expression and activation in hearts of tight skin mice.
Topics: Animals; Apolipoprotein A-I; Apoptosis; Disease Models, Animal; Echocardiography; Endothelial Cells; | 2012 |
T-helper-1-cell cytokines drive cancer into senescence.
Topics: Animals; Antigens, Polyomavirus Transforming; Cell Cycle; Cell Proliferation; Cellular Senescence; C | 2013 |
Phosphorylation of neuronal nitric oxide synthase at Ser847 by CaM-KII in the hippocampus of rat brain after transient forebrain ischemia.
Topics: Animals; Benzylamines; Blood Pressure; Body Temperature; Calcium-Calmodulin-Dependent Protein Kinase | 2002 |
Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation | 2003 |
Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction.
Topics: Acetylglucosamine; Animals; Diabetes Complications; Disease Models, Animal; Enzyme Activation; Erect | 2005 |
Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.
Topics: Animals; Brain; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Hyperinsul | 2005 |
Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Endothelium, Vascular; | 2006 |
Molecular verification of stereotactic radiotherapy in rats using ATMpS1981 immunofluorescence.
Topics: Animals; Brain; Brain Chemistry; Brain Neoplasms; Disease Models, Animal; Fluorescent Antibody Techn | 2006 |
Melatonin modulates signal transduction pathways and apoptosis in experimental colitis.
Topics: Animals; Apoptosis; Colitis; Cytokines; Dinitrofluorobenzene; Disease Models, Animal; JNK Mitogen-Ac | 2006 |
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Benzoates; Carrageenan; Dinucleoside Phosphates | 2007 |
O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII.
Topics: Animals; Antibodies, Monoclonal; Binding Sites; Coagulants; Disease Models, Animal; Drug Stability; | 2007 |
Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site.
Topics: Amino Acid Sequence; Animals; Apoptosis; Caspase 7; Caspase Inhibitors; CDC2 Protein Kinase; CHO Cel | 2007 |
Serine phosphate, threonine phosphate and gamma-carboxyglutamic acid in normal and experimentally induced, pathologically calcified rat skin (topical cutaneous calciphylaxis).
Topics: 1-Carboxyglutamic Acid; Animals; Calciphylaxis; Dihydrotachysterol; Disease Models, Animal; Female; | 1981 |