phosphoserine has been researched along with Diabetes Mellitus, Type 2 in 12 studies
Phosphoserine: The phosphoric acid ester of serine.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin resistance is characterised by a decrease in insulin effect on glucose transport in muscle and adipose tIssue." | 2.42 | Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling. ( Barrès, R; Gonzalez, T; Grémeaux, T; Gual, P; Le Marchand-Brustel, Y; Tanti, JF, 2004) |
| "Platelets in patients with type 2 diabetes (T2D) are more sensitive to aggregation, which has been attributed to a reduced ability to produce nitric oxide (NO)." | 1.38 | Dehydroepiandrosterone prevents the aggregation of platelets obtained from postmenopausal women with type 2 diabetes mellitus through the activation of the PKC/eNOS/NO pathway. ( Gomez, GI; Moreno, M; Muñoz, YC; Solis, CL; Valladares, LE; Velarde, V, 2012) |
| "Accordingly, type 2 diabetes characterized by insulin resistance is associated with an increased risk of developing Alzheimer's disease." | 1.33 | Peripheral hyperinsulinemia promotes tau phosphorylation in vivo. ( Bruning, JC; Freude, S; Krone, W; Leeser, U; Plum, L; Schnitker, J; Schubert, M; Udelhoven, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, CT | 1 |
| Chen, KY | 1 |
| Wang, W | 1 |
| Chiu, JY | 1 |
| Wu, D | 1 |
| Chao, TY | 1 |
| Hu, CJ | 1 |
| Chau, KD | 1 |
| Bamodu, OA | 1 |
| Choi, JH | 1 |
| Choi, SS | 1 |
| Kim, ES | 1 |
| Jedrychowski, MP | 1 |
| Yang, YR | 1 |
| Jang, HJ | 1 |
| Suh, PG | 1 |
| Banks, AS | 1 |
| Gygi, SP | 1 |
| Spiegelman, BM | 1 |
| Gogg, S | 1 |
| Smith, U | 1 |
| Jansson, PA | 1 |
| Muñoz, YC | 1 |
| Gomez, GI | 1 |
| Moreno, M | 1 |
| Solis, CL | 1 |
| Valladares, LE | 1 |
| Velarde, V | 1 |
| Bouzakri, K | 1 |
| Roques, M | 1 |
| Gual, P | 2 |
| Espinosa, S | 1 |
| Guebre-Egziabher, F | 1 |
| Riou, JP | 1 |
| Laville, M | 2 |
| Le Marchand-Brustel, Y | 2 |
| Tanti, JF | 2 |
| Vidal, H | 2 |
| Grémeaux, T | 1 |
| Gonzalez, T | 1 |
| Barrès, R | 1 |
| Freude, S | 1 |
| Plum, L | 1 |
| Schnitker, J | 1 |
| Leeser, U | 1 |
| Udelhoven, M | 1 |
| Krone, W | 1 |
| Bruning, JC | 1 |
| Schubert, M | 1 |
| Li, X | 1 |
| Monks, B | 1 |
| Ge, Q | 1 |
| Birnbaum, MJ | 1 |
| Cozzone, D | 1 |
| Fröjdö, S | 1 |
| Disse, E | 1 |
| Debard, C | 1 |
| Pirola, L | 1 |
| Dunaif, A | 1 |
| Xia, J | 1 |
| Book, CB | 1 |
| Schenker, E | 1 |
| Tang, Z | 1 |
| Häring, HU | 1 |
| Kellerer, M | 1 |
| Mosthaf, L | 1 |
| Echwald, SM | 1 |
| Bach, H | 1 |
| Vestergaard, H | 1 |
| Richelsen, B | 1 |
| Kristensen, K | 1 |
| Drivsholm, T | 1 |
| Borch-Johnsen, K | 1 |
| Hansen, T | 1 |
| Pedersen, O | 1 |
2 reviews available for phosphoserine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Homeostasis; Humans; Insulin; Insulin | 2004 |
Modulation of insulin signalling in non-insulin-dependent diabetes mellitus: significance of altered receptor isoform patterns and mechanisms of glucose-induced receptor modulation.
Topics: Animals; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Phosphoserine; Receptor, Insulin; Sign | 1994 |
10 other studies available for phosphoserine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling.
Topics: alpha-Synuclein; Animals; Diabetes Mellitus, Type 2; Disease Progression; Dopaminergic Neurons; Geno | 2020 |
Thrap3 docks on phosphoserine 273 of PPARγ and controls diabetic gene programming.
Topics: 3T3 Cells; Adipokines; Animals; Cells, Cultured; Cyclin-Dependent Kinase 5; Diabetes Mellitus, Type | 2014 |
Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1.
Topics: Adipose Tissue; Biopsy, Needle; Diabetes Mellitus, Type 2; Endothelin-1; Endothelium, Vascular; Enzy | 2009 |
Dehydroepiandrosterone prevents the aggregation of platelets obtained from postmenopausal women with type 2 diabetes mellitus through the activation of the PKC/eNOS/NO pathway.
Topics: Blood Platelets; Cyclic GMP; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Enzyme Activation; E | 2012 |
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.
Topics: Biopsy; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hexokin | 2003 |
Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.
Topics: Animals; Brain; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Hyperinsul | 2005 |
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.
Topics: Animals; Cell Line, Tumor; Chromatin; Diabetes Mellitus, Type 2; Down-Regulation; Gene Expression Re | 2007 |
Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 2; Enzyme Activation; Female; Humans; Insulin; Isoenzymes; Male; Midd | 2008 |
Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome.
Topics: Adult; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Fibroblasts; Humans; Insul | 1995 |
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.
Topics: Amino Acid Substitution; Animals; Diabetes Mellitus, Type 2; Female; Genetic Variation; Genotype; Hu | 2002 |