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phosphoserine and Cancer of Prostate

phosphoserine has been researched along with Cancer of Prostate in 14 studies

Phosphoserine: The phosphoric acid ester of serine.

Research Excerpts

ExcerptRelevanceReference
"The normal prostate development and prostate cancer progression are mediated by androgen receptor (AR)."1.37Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5. ( Chen, MC; Chiang, MC; Hsu, FN; Huang, PH; Lee, GS; Lee, YT; Lin, E; Lin, H, 2011)
"Prostate cancer is the most frequently diagnosed male malignancy."1.37Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5. ( Chen, MC; Chiang, MC; Hsu, FN; Huang, PH; Lee, GS; Lee, YT; Lin, E; Lin, H, 2011)
"These results demonstrate that, in prostate cancer cells, the efficacy of chemotherapy may be limited by its effects on the intracellular signaling pathways found within the cell."1.35Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells. ( Chappell, WH; Lee, JT; McCubrey, JA; Steelman, LS, 2008)
"Interestingly, 10 of 15 primary prostate cancers examined by Western blotting overexpressed acid ceramidase (AC), suggesting that ceramide deacylation might serve to negate elevated levels of ceramide, creating a more antiapoptotic phenotype."1.33Modulation of ceramide metabolism enhances viral protein apoptin's cytotoxicity in prostate cancer. ( Bielawska, A; Bielawski, J; Dong, JY; El-Zawahry, AM; Elojeimy, S; Guo, GW; Hannun, YA; Holman, DH; Keane, T; Liu, X; Norris, JS; Rubinchik, S; Tavassoli, M, 2006)
"Resveratrol causes apoptosis in DU 145 prostate cancer cells."1.31Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line. ( Bennett, JA; Davis, FB; Davis, PJ; Lin, HY; Martino, LJ; Shih, A; Tang, HY, 2002)
"Whereas the early stage of prostate cancer is marked by excessive proliferation, in advanced stages of the disease, a decreased apoptotic death rate (increased cell survival) also contributes to net tumor growth."1.31Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. ( Bedolla, R; Brattain, M; Ghosh, PM; Kreisberg, JI; Malik, SN; Prihoda, T; Troyer, DA, 2002)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Wen, S1
Wei, Y1
Zen, C1
Xiong, W1
Niu, Y1
Zhao, Y1
Cobb, LJ1
Mehta, H1
Cohen, P1
Fu, YM1
Lin, H2
Liu, X2
Fang, W1
Meadows, GG1
Hsu, FN1
Chen, MC1
Chiang, MC1
Lin, E1
Lee, YT1
Huang, PH1
Lee, GS1
Jones, SE1
Palmer, TM1
Mao, L1
Dauchy, RT1
Blask, DE1
Slakey, LM1
Xiang, S1
Yuan, L1
Dauchy, EM1
Shan, B1
Brainard, GC1
Hanifin, JP1
Frasch, T1
Duplessis, TT1
Hill, SM1
Liu, T1
Li, Y1
Gu, H1
Zhu, G1
Li, J1
Cao, L1
Li, F1
Gupta, K1
Thakur, VS1
Bhaskaran, N1
Nawab, A1
Babcook, MA1
Jackson, MW1
Gupta, S1
Lin, HY1
Shih, A1
Davis, FB1
Tang, HY1
Martino, LJ1
Bennett, JA1
Davis, PJ1
Elojeimy, S1
El-Zawahry, AM1
Holman, DH1
Bielawska, A1
Bielawski, J1
Rubinchik, S1
Guo, GW1
Dong, JY1
Keane, T1
Hannun, YA1
Tavassoli, M1
Norris, JS1
Chen, S1
Xu, Y1
Yuan, X1
Bubley, GJ1
Balk, SP1
Lee, JT1
Steelman, LS1
Chappell, WH1
McCubrey, JA1
Lapko, VN1
Wells, TA1
Song, PS1
Malik, SN1
Brattain, M1
Ghosh, PM1
Troyer, DA1
Prihoda, T1
Bedolla, R1
Kreisberg, JI1

Other Studies

14 other studies available for phosphoserine and Cancer of Prostate

ArticleYear
Long non-coding RNA NEAT1 promotes bone metastasis of prostate cancer through N6-methyladenosine.
    Molecular cancer, 2020, 12-12, Volume: 19, Issue:1

    Topics: Adenosine; Aged; Aged, 80 and over; Animals; Bone Neoplasms; Cell Line, Tumor; Core Binding Factor A

2020
Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation.
    Molecular endocrinology (Baltimore, Md.), 2009, Volume: 23, Issue:10

    Topics: Amino Acid Sequence; Animals; Apoptosis; Casein Kinase II; Cell Line, Tumor; Cell Nucleus; Cell Surv

2009
Cell death of prostate cancer cells by specific amino acid restriction depends on alterations of glucose metabolism.
    Journal of cellular physiology, 2010, Volume: 224, Issue:2

    Topics: Amino Acids; Cell Death; Cell Line, Tumor; Fluorescent Antibody Technique; Glucose; Glycogen Synthas

2010
Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5.
    The Journal of biological chemistry, 2011, Sep-23, Volume: 286, Issue:38

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 5; Humans; Male; Mice; Models

2011
Protein kinase A-mediated phosphorylation of RhoA on serine 188 triggers the rapid induction of a neuroendocrine-like phenotype in prostate cancer epithelial cells.
    Cellular signalling, 2012, Volume: 24, Issue:8

    Topics: Carcinoma, Neuroendocrine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Human

2012
Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β.
    Molecular endocrinology (Baltimore, Md.), 2012, Volume: 26, Issue:11

    Topics: Animals; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Circadian Rhythm; Enzyme Activation; Epit

2012
p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2).
    The Journal of biological chemistry, 2013, Feb-01, Volume: 288, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chlorocebus aethiops

2013
Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Acetylation; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Line, Tumor; Cell Survival; C

2012
Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line.
    The Journal of urology, 2002, Volume: 168, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Mutational Analysis; Enzyme Activation; Gene Expre

2002
Modulation of ceramide metabolism enhances viral protein apoptin's cytotoxicity in prostate cancer.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2006, Volume: 14, Issue:5

    Topics: Adenoviridae; Animals; Apoptosis; Capsid Proteins; Caspases; Cell Line, Tumor; Ceramides; Enzyme Inh

2006
Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Oct-24, Volume: 103, Issue:43

    Topics: Androgens; CDC2 Protein Kinase; Cell Line, Tumor; Humans; Male; Phosphorylation; Phosphoserine; Pros

2006
Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells.
    Cell cycle (Georgetown, Tex.), 2008, Mar-01, Volume: 7, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme

2008
Protein kinase A-catalyzed phosphorylation and its effect on conformation in phytochrome A.
    Biochemistry, 1996, May-28, Volume: 35, Issue:21

    Topics: Acid Phosphatase; Adenoma; Adenosine Triphosphate; Amino Acid Sequence; Animals; Avena; Cattle; Circ

1996
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:4

    Topics: Humans; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Ki

2002