phosphoserine has been researched along with Breast Cancer in 54 studies
Phosphoserine: The phosphoric acid ester of serine.
Excerpt | Relevance | Reference |
---|---|---|
"Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients." | 7.85 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients." | 5.46 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"Here, we report the development of the breast cancer cell model MCF7::C1199 having Rac1 enhanced activity with the aim of evaluating the role of Rac1 in acquired endocrine resistance." | 5.46 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"Herein, using the T47D breast cancer model, we probed mechanisms of cell cycle-dependent PR action." | 5.40 | Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. ( Daniel, AR; Diep, CH; Dressing, GE; Hagan, CR; Knudsen, KE; Knutson, TP; Lange, CA; Schiewer, MJ, 2014) |
"Analysis of 65 ErbB2-expressing primary breast cancers reveals a highly significant relationship between Ser1113 phosphorylation and EGFR overexpression (p < 0." | 5.31 | Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer. ( Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H, 2001) |
" In this report, we show that cervical cancer HeLa cells and breast cancer MDA MB 231 cells with reduced GRK5 expression display increased sensitivity to the apoptotic effects of paclitaxel (Taxol)." | 3.91 | G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel. ( Alp, D; Benovic, JL; Jacinto, AZ; Lagman, J; Lee, CS; Peng, N; Sayegh, P; So, CH; Sok, V; Sulon, SM, 2019) |
"Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients." | 3.85 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"These findings may explain in part the aneuploidy observed in BRCA2-mutated tumors." | 1.56 | Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1. ( Beaurepere, R; Boucherit, V; Carreira, A; Duchambon, P; Ehlén, Å; El Marjou, A; Julien, M; Martin, C; Miron, S; Ropars, V; Sessa, G; Theillet, FX; Zinn-Justin, S, 2020) |
"Cancer metastasis accounts for the major cause of cancer-related deaths." | 1.56 | Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis. ( Cai, Z; Chilton, FH; D'Agostino, RB; Furdui, CM; Han, F; Hsu, CC; Hsu, FC; Huang, CY; Jin, G; Kucera, GL; Li, CF; Lin, HK; Liu, C; Pan, BS; Parks, JS; Pasche, B; Peng, D; Rezaeian, AH; Tsai, FJ; Wang, CY; Wang, G; Wang, YH; Watabe, K; Wu, SY; Yang, SC; Zhang, A; Zhang, W; Zhang, X, 2020) |
"Approximately 70% of breast cancer cells express oestrogen receptor alpha (ERα)." | 1.46 | A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells. ( Bando, Y; Chen, YA; Honda, J; Imoto, I; Izumi, K; Katagiri, T; Komatsu, M; Miyoshi, Y; Mizuguchi, K; Ono, M; Sasa, M; Shima, H; Yoshimaru, T, 2017) |
"Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients." | 1.46 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"Here, we report the development of the breast cancer cell model MCF7::C1199 having Rac1 enhanced activity with the aim of evaluating the role of Rac1 in acquired endocrine resistance." | 1.46 | Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. ( Alonso, DF; Cardama, GA; Comin, MJ; Gomez, DE; Gonzalez, N; Menna, PL; Pifano, M; Segatori, VI, 2017) |
"The inhibitory effects of PP4c on breast cancer cell survival and growth were lost in PEA15 knockdown cells, confirming that PP4c action is mediated, at least in part, through the de-phosphorylation of apoptosis regulator PEA15." | 1.43 | The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells. ( Mohammed, HN; Mourtada-Maarabouni, M; Pickard, MR, 2016) |
"Our work shows that PP4 regulates breast cancer cell survival and identifies a novel PP4c-PEA15 signalling axis in the control of breast cancer cell survival." | 1.43 | The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells. ( Mohammed, HN; Mourtada-Maarabouni, M; Pickard, MR, 2016) |
"Herein, using the T47D breast cancer model, we probed mechanisms of cell cycle-dependent PR action." | 1.40 | Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. ( Daniel, AR; Diep, CH; Dressing, GE; Hagan, CR; Knudsen, KE; Knutson, TP; Lange, CA; Schiewer, MJ, 2014) |
"Here, we have used human breast cancer T47D cells stably overexpressing PAK1 wild type or PAK1 Y3F mutant in which Tyr(s) 153, 201, and 285 were mutated to phenylalanines to demonstrate that phosphorylation of these three tyrosines are required for maximal PRL-dependent ruffling." | 1.39 | Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A. ( Cook, L; Diakonova, M; Hammer, A; Li, Q; Mattingly, RR; Oladimeji, P; Rider, L, 2013) |
"We therefore examined Axin1 in breast cancer and report decreased AXIN1 expression and a shift in the ratio of expression of two naturally occurring AXIN1 splice variants." | 1.38 | Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression. ( Arnold, H; Chen, D; Daniel, CJ; Farrell, AS; Janghorban, M; Laraway, BJ; Lum, L; Scanlan, C; Sears, R; Troxell, M; Zhang, X, 2012) |
"In tamoxifen-resistant breast cancer cells, BG alone or in combination with antiestrogen (tamoxifen [TAM]/ICI 182,780 [fulvestrant, Faslodex]) therapy enhances p53 upregulated modulator of apoptosis (PUMA) expression, cytochrome C release and poly (ADP-ribose) polymerase (PARP) cleavage, all indicative of apoptosis." | 1.38 | MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. ( Baidas, S; Baker, CH; Bobustuc, GC; Caparas, ML; Constantino, SM; Isley, B; Jeudy, S; Konduri, SD; Limaye, A; Maddipatla, S; Shah, N; Smith, JS; Srivenugopal, KS, 2012) |
"Co-treatment of etoposide and KG-135 markedly elevated the expression and phosphorylation at the serine 15 residue of p53 as well as the cellular levels of Bax and p21(Waf1/Cip1)." | 1.36 | Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. ( Cho, SJ; Choi, JS; Kim, HY; Lee, SK; Lee, WH; Park, BD; Park, JH; Surh, YJ, 2010) |
"Importantly, Parvin-beta suppressed breast cancer growth in vivo, with associated decreased proliferation." | 1.35 | Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation. ( Bowser, MJ; Delemos, AS; Hannigan, GE; Johnstone, CN; Liu, Y; Mongroo, PS; Rich, AS; Rustgi, AK; Schupp, M; Tobias, JW, 2008) |
"Taken together, treatment of breast cancer cells that overexpress HER2 with the anti-HER2 antibody trastuzumab inhibits CDK2, Rb phosphorylation, E2F activity, NPAT, and histone H4 via PI3K signaling that are needed for both DNA and histone synthesis during progression from G(1) phase to S phase of the cell cycle." | 1.33 | Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway. ( Bast, RC; Bedrosian, I; Keyomarsi, K; Le, XF; Lee, MH; Lu, Z; Mao, W; Murray, M; Zhao, J, 2006) |
"Analysis of 65 ErbB2-expressing primary breast cancers reveals a highly significant relationship between Ser1113 phosphorylation and EGFR overexpression (p < 0." | 1.31 | Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer. ( Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H, 2001) |
"Casein kinase II was found to phosphorylate the purified recombinant hER on serine 167 in vitro." | 1.29 | Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor. ( Arnold, SF; Jaffe, H; Notides, AC; Obourn, JD, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.85) | 18.7374 |
1990's | 5 (9.26) | 18.2507 |
2000's | 18 (33.33) | 29.6817 |
2010's | 23 (42.59) | 24.3611 |
2020's | 7 (12.96) | 2.80 |
Authors | Studies |
---|---|
Zhu, H | 1 |
Su, Z | 1 |
Ning, J | 1 |
Zhou, L | 1 |
Tan, L | 1 |
Sayed, S | 1 |
Song, J | 1 |
Wang, Z | 1 |
Li, H | 1 |
Sun, Q | 1 |
Liu, S | 1 |
Sha, O | 1 |
Leng, F | 1 |
Chen, X | 1 |
Lu, D | 1 |
Oviya, RP | 1 |
Thangaretnam, KP | 1 |
Ramachandran, B | 1 |
Ramanathan, P | 1 |
Jayavelu, S | 1 |
Gopal, G | 1 |
Rajkumar, T | 1 |
Ehlén, Å | 1 |
Martin, C | 1 |
Miron, S | 1 |
Julien, M | 1 |
Theillet, FX | 1 |
Ropars, V | 1 |
Sessa, G | 1 |
Beaurepere, R | 1 |
Boucherit, V | 1 |
Duchambon, P | 1 |
El Marjou, A | 1 |
Zinn-Justin, S | 1 |
Carreira, A | 1 |
Chen, K | 1 |
Jiao, X | 1 |
Di Rocco, A | 1 |
Shen, D | 1 |
Xu, S | 1 |
Ertel, A | 1 |
Yu, Z | 1 |
Di Sante, G | 1 |
Wang, M | 1 |
Li, Z | 1 |
Pestell, TG | 1 |
Casimiro, MC | 1 |
Skordalakes, E | 1 |
Achilefu, S | 1 |
Pestell, RG | 1 |
Kim, JJ | 1 |
Lee, SY | 1 |
Choi, JH | 1 |
Woo, HG | 1 |
Xhemalce, B | 1 |
Miller, KM | 1 |
Dimri, S | 1 |
Malhotra, R | 1 |
Shet, T | 1 |
Mokal, S | 1 |
Gupta, S | 1 |
De, A | 1 |
Cai, Z | 1 |
Li, CF | 1 |
Han, F | 1 |
Liu, C | 1 |
Zhang, A | 1 |
Hsu, CC | 1 |
Peng, D | 1 |
Zhang, X | 2 |
Jin, G | 1 |
Rezaeian, AH | 1 |
Wang, G | 1 |
Zhang, W | 1 |
Pan, BS | 1 |
Wang, CY | 1 |
Wang, YH | 1 |
Wu, SY | 1 |
Yang, SC | 1 |
Hsu, FC | 1 |
D'Agostino, RB | 1 |
Furdui, CM | 1 |
Kucera, GL | 1 |
Parks, JS | 1 |
Chilton, FH | 1 |
Huang, CY | 1 |
Tsai, FJ | 1 |
Pasche, B | 1 |
Watabe, K | 1 |
Lin, HK | 1 |
Yoshimaru, T | 1 |
Ono, M | 1 |
Bando, Y | 1 |
Chen, YA | 1 |
Mizuguchi, K | 1 |
Shima, H | 1 |
Komatsu, M | 1 |
Imoto, I | 1 |
Izumi, K | 1 |
Honda, J | 1 |
Miyoshi, Y | 1 |
Sasa, M | 1 |
Katagiri, T | 1 |
Lagman, J | 1 |
Sayegh, P | 1 |
Lee, CS | 1 |
Sulon, SM | 1 |
Jacinto, AZ | 1 |
Sok, V | 1 |
Peng, N | 1 |
Alp, D | 1 |
Benovic, JL | 1 |
So, CH | 1 |
Liu, RM | 1 |
Tian, XY | 1 |
Huang, XT | 1 |
Zhou, H | 1 |
Wei, C | 1 |
Cao, Y | 2 |
Yang, X | 1 |
Zheng, Z | 1 |
Guan, K | 1 |
Wang, Q | 2 |
Tai, Y | 1 |
Zhang, Y | 1 |
Ma, S | 1 |
Ge, X | 1 |
Xu, C | 1 |
Li, J | 1 |
Yan, H | 1 |
Ling, Y | 1 |
Song, T | 1 |
Zhu, L | 1 |
Zhang, B | 1 |
Xu, Q | 1 |
Hu, C | 1 |
Bian, XW | 1 |
He, X | 1 |
Zhong, H | 1 |
Dressing, GE | 1 |
Knutson, TP | 1 |
Schiewer, MJ | 1 |
Daniel, AR | 1 |
Hagan, CR | 1 |
Diep, CH | 1 |
Knudsen, KE | 1 |
Lange, CA | 2 |
Li, D | 1 |
Yallowitz, A | 1 |
Ozog, L | 1 |
Marchenko, N | 1 |
Lee, MS | 1 |
Kim, S | 1 |
Kim, BG | 1 |
Won, C | 1 |
Nam, SH | 1 |
Kang, S | 1 |
Kim, HJ | 1 |
Kang, M | 1 |
Ryu, J | 1 |
Song, HE | 1 |
Lee, D | 1 |
Ye, SK | 1 |
Jeon, NL | 1 |
Kim, TY | 1 |
Cho, NH | 1 |
Lee, JW | 1 |
Abdel-Fatah, TM | 1 |
Middleton, FK | 1 |
Arora, A | 1 |
Agarwal, D | 1 |
Chen, T | 1 |
Moseley, PM | 1 |
Perry, C | 1 |
Doherty, R | 1 |
Chan, S | 1 |
Green, AR | 1 |
Rakha, E | 1 |
Ball, G | 1 |
Ellis, IO | 1 |
Curtin, NJ | 1 |
Madhusudan, S | 1 |
Hicks, MJ | 1 |
Hu, Q | 1 |
Macrae, E | 1 |
DeWille, J | 1 |
Sau, A | 1 |
Lau, R | 1 |
Cabrita, MA | 1 |
Nolan, E | 1 |
Crooks, PA | 1 |
Visvader, JE | 1 |
Pratt, MA | 1 |
Mohammed, HN | 1 |
Pickard, MR | 1 |
Mourtada-Maarabouni, M | 1 |
Bhattacharya, R | 1 |
Mukherjee, N | 1 |
Dasgupta, H | 1 |
Islam, MS | 1 |
Alam, N | 1 |
Roy, A | 1 |
Das, P | 1 |
Roychoudhury, S | 1 |
Panda, CK | 1 |
Gonzalez, N | 1 |
Cardama, GA | 1 |
Comin, MJ | 1 |
Segatori, VI | 1 |
Pifano, M | 1 |
Alonso, DF | 1 |
Gomez, DE | 1 |
Menna, PL | 1 |
Vanneste, M | 1 |
Hanoux, V | 1 |
Bouakka, M | 1 |
Bonnamy, PJ | 1 |
Neubauer, H | 1 |
Clare, SE | 1 |
Wozny, W | 1 |
Schwall, GP | 1 |
Poznanovic, S | 1 |
Stegmann, W | 1 |
Vogel, U | 1 |
Sotlar, K | 1 |
Wallwiener, D | 1 |
Kurek, R | 1 |
Fehm, T | 1 |
Cahill, MA | 1 |
Li, C | 1 |
Liang, YY | 1 |
Feng, XH | 1 |
Tsai, SY | 1 |
Tsai, MJ | 1 |
O'Malley, BW | 1 |
Hong, X | 1 |
Liu, Y | 2 |
Hu, G | 1 |
Zhao, D | 1 |
Shen, J | 1 |
Shen, F | 1 |
Cao, X | 1 |
Law, M | 1 |
Corsino, P | 1 |
Parker, NT | 1 |
Law, BK | 1 |
Lee, WH | 1 |
Choi, JS | 1 |
Kim, HY | 1 |
Park, JH | 1 |
Park, BD | 1 |
Cho, SJ | 1 |
Lee, SK | 1 |
Surh, YJ | 1 |
Andersen, JN | 1 |
Sathyanarayanan, S | 1 |
Di Bacco, A | 1 |
Chi, A | 1 |
Zhang, T | 1 |
Chen, AH | 1 |
Dolinski, B | 1 |
Kraus, M | 1 |
Roberts, B | 1 |
Arthur, W | 1 |
Klinghoffer, RA | 1 |
Gargano, D | 1 |
Li, L | 1 |
Feldman, I | 1 |
Lynch, B | 1 |
Rush, J | 1 |
Hendrickson, RC | 1 |
Blume-Jensen, P | 1 |
Paweletz, CP | 1 |
Woolley, AG | 1 |
Algie, M | 1 |
Samuel, W | 1 |
Harfoot, R | 1 |
Wiles, A | 1 |
Hung, NA | 1 |
Tan, PH | 1 |
Hains, P | 1 |
Valova, VA | 1 |
Huschtscha, L | 1 |
Royds, JA | 1 |
Perez, D | 1 |
Yoon, HS | 1 |
Cohen, SB | 1 |
Robinson, PJ | 1 |
Bay, BH | 1 |
Lasham, A | 1 |
Braithwaite, AW | 1 |
Farrell, AS | 1 |
Daniel, CJ | 1 |
Arnold, H | 1 |
Scanlan, C | 1 |
Laraway, BJ | 1 |
Janghorban, M | 1 |
Lum, L | 1 |
Chen, D | 1 |
Troxell, M | 1 |
Sears, R | 1 |
Khan, JA | 1 |
Amazit, L | 1 |
Bellance, C | 1 |
Guiochon-Mantel, A | 1 |
Lombès, M | 1 |
Loosfelt, H | 1 |
Bobustuc, GC | 1 |
Smith, JS | 1 |
Maddipatla, S | 1 |
Jeudy, S | 1 |
Limaye, A | 1 |
Isley, B | 1 |
Caparas, ML | 1 |
Constantino, SM | 1 |
Shah, N | 1 |
Baker, CH | 1 |
Srivenugopal, KS | 1 |
Baidas, S | 1 |
Konduri, SD | 1 |
Mao, L | 1 |
Dauchy, RT | 1 |
Blask, DE | 1 |
Slakey, LM | 1 |
Xiang, S | 1 |
Yuan, L | 1 |
Dauchy, EM | 1 |
Shan, B | 1 |
Brainard, GC | 1 |
Hanifin, JP | 1 |
Frasch, T | 1 |
Duplessis, TT | 1 |
Hill, SM | 1 |
Hammer, A | 1 |
Rider, L | 1 |
Oladimeji, P | 1 |
Cook, L | 1 |
Li, Q | 1 |
Mattingly, RR | 1 |
Diakonova, M | 1 |
Hofseth, LJ | 1 |
Saito, S | 1 |
Hussain, SP | 1 |
Espey, MG | 1 |
Miranda, KM | 1 |
Araki, Y | 1 |
Jhappan, C | 1 |
Higashimoto, Y | 1 |
He, P | 1 |
Linke, SP | 1 |
Quezado, MM | 1 |
Zurer, I | 1 |
Rotter, V | 1 |
Wink, DA | 1 |
Appella, E | 1 |
Harris, CC | 1 |
Shen, WH | 1 |
Yin, Y | 1 |
Broussard, SR | 1 |
McCusker, RH | 1 |
Freund, GG | 1 |
Dantzer, R | 1 |
Kelley, KW | 1 |
Murphy, L | 1 |
Cherlet, T | 1 |
Adeyinka, A | 1 |
Niu, Y | 1 |
Snell, L | 1 |
Watson, P | 1 |
Wesierska-Gadek, J | 1 |
Gueorguieva, M | 1 |
Horky, M | 1 |
Gburcik, V | 1 |
Bot, N | 1 |
Maggiolini, M | 1 |
Picard, D | 1 |
Yamashita, H | 1 |
Nishio, M | 1 |
Kobayashi, S | 1 |
Ando, Y | 1 |
Sugiura, H | 1 |
Zhang, Z | 1 |
Hamaguchi, M | 1 |
Mita, K | 1 |
Fujii, Y | 1 |
Iwase, H | 1 |
Le, XF | 1 |
Bedrosian, I | 1 |
Mao, W | 1 |
Murray, M | 1 |
Lu, Z | 1 |
Keyomarsi, K | 1 |
Lee, MH | 1 |
Zhao, J | 1 |
Bast, RC | 1 |
Sarwar, N | 1 |
Kim, JS | 1 |
Jiang, J | 1 |
Peston, D | 1 |
Sinnett, HD | 1 |
Madden, P | 1 |
Gee, JM | 1 |
Nicholson, RI | 1 |
Lykkesfeldt, AE | 1 |
Shousha, S | 1 |
Coombes, RC | 1 |
Ali, S | 1 |
Rodrik, V | 1 |
Gomes, E | 1 |
Hui, L | 1 |
Rockwell, P | 1 |
Foster, DA | 1 |
Sekine, Y | 1 |
Ikeda, O | 1 |
Hayakawa, Y | 1 |
Tsuji, S | 1 |
Imoto, S | 1 |
Aoki, N | 1 |
Sugiyama, K | 1 |
Matsuda, T | 1 |
Johnstone, CN | 1 |
Mongroo, PS | 1 |
Rich, AS | 1 |
Schupp, M | 1 |
Bowser, MJ | 1 |
Delemos, AS | 1 |
Tobias, JW | 1 |
Hannigan, GE | 1 |
Rustgi, AK | 1 |
Arnold, SF | 1 |
Obourn, JD | 1 |
Jaffe, H | 1 |
Notides, AC | 1 |
Geier, A | 1 |
Hemi, R | 1 |
Haimsohn, M | 1 |
Beery, R | 1 |
Karasik, A | 1 |
Craig, AL | 2 |
Burch, L | 1 |
Vojtesek, B | 1 |
Mikutowska, J | 1 |
Thompson, A | 1 |
Hupp, TR | 2 |
Blaydes, JP | 1 |
Burch, LR | 1 |
Thompson, AM | 1 |
Shen, T | 1 |
Horwitz, KB | 1 |
Ouyang, X | 1 |
Gulliford, T | 1 |
Zhang, H | 1 |
Smith, G | 1 |
Huang, G | 1 |
Epstein, RJ | 1 |
Clark, DE | 1 |
Poteet-Smith, CE | 1 |
Smith, JA | 1 |
Lannigan, DA | 1 |
Métivier, R | 1 |
Gay, FA | 1 |
Hübner, MR | 1 |
Flouriot, G | 1 |
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Gannon, F | 1 |
Kah, O | 1 |
Pakdel, F | 1 |
Lin, YZ | 1 |
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Clinton, GM | 1 |
Schütze, S | 1 |
Scheurich, P | 1 |
Pfizenmaier, K | 1 |
Krönke, M | 1 |
54 other studies available for phosphoserine and Breast Cancer
Article | Year |
---|---|
Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer.
Topics: Animals; beta Catenin; Breast Neoplasms; Casein Kinase I; Cell Line, Tumor; Cell Movement; Cell Prol | 2021 |
Mitochondrial ribosomal small subunit (MRPS) MRPS23 protein-protein interaction reveals phosphorylation by CDK11-p58 affecting cell proliferation and knockdown of MRPS23 sensitizes breast cancer cells to CDK1 inhibitors.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; C | 2022 |
Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1.
Topics: Aneuploidy; BRCA2 Protein; Breast Neoplasms; Cell Cycle Proteins; Chromosome Segregation; Chromosome | 2020 |
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Membrane; Cyclin D1; Cyclin-Dependent Kinases; Female; Ge | 2020 |
PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
Topics: Acetylation; Amino Acid Sequence; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; BRCA2 Prote | 2020 |
Noncanonical pS727 post translational modification dictates major STAT3 activation and downstream functions in breast cancer.
Topics: Animals; Anthelmintics; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice | 2020 |
Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.
Topics: AMP-Activated Protein Kinases; Animals; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Cell S | 2020 |
A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.
Topics: A Kinase Anchor Proteins; Amino Acid Sequence; Breast Neoplasms; Cell Line, Tumor; Cyclic AMP-Depend | 2017 |
G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel.
Topics: Acetylation; Apoptosis; Biocatalysis; Breast Neoplasms; Docetaxel; Drug Resistance, Neoplasm; Female | 2019 |
Transfer of Ser7 phosphorylated CENP-A from centromere to midbody during mitosis in MCF-7 cells.
Topics: Adenocarcinoma; Autoantigens; Biological Transport; Breast Neoplasms; Centromere; Centromere Protein | 2013 |
Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Estrogen Receptor alpha; F | 2014 |
Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Extracts; Cell Line, Tumor; Chlorocebus aethiops; COS Ce | 2014 |
A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; DNA-Binding Proteins; ErbB Receptors; Fem | 2014 |
Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation.
Topics: Actins; Animals; Breast Neoplasms; Cattle; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Nucl | 2014 |
Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.
Topics: Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chec | 2015 |
Mitogen-activated protein kinase signaling controls basal and oncostatin M-mediated JUNB gene expression.
Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Extracellular Space; Female; Gene Expression Regulat | 2015 |
Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Breast; Breast Neoplasms; Cell Line, | 2016 |
The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr | 2016 |
Frequent alterations of SLIT2-ROBO1-CDC42 signalling pathway in breast cancer: clinicopathological correlation.
Topics: Adult; Aged; Breast Neoplasms; cdc42 GTP-Binding Protein; Disease Progression; DNA Methylation; Fema | 2016 |
Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells.
Topics: Breast Neoplasms; Drug Resistance, Neoplasm; Estrogens; Female; Humans; MCF-7 Cells; Models, Biologi | 2017 |
Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells.
Topics: Acetylation; Breast Neoplasms; E1A-Associated p300 Protein; Estrogen Receptor alpha; Estrogens; Fema | 2017 |
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1.
Topics: Amino Acid Substitution; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninf | 2008 |
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.
Topics: Breast Neoplasms; Gene Expression Regulation; Genome; HeLa Cells; Humans; Nuclear Receptor Coactivat | 2008 |
EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma.
Topics: Animals; Antigens, Neoplasm; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, | 2009 |
Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-kappaB using in silico molecular docking.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclic AMP Res | 2010 |
Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation.
Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Carcinoma, Hepatocellular; | 2010 |
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.
Topics: Adaptor Proteins, Signal Transducing; Animals; Basophils; Biomarkers, Tumor; Breast Neoplasms; Cell | 2010 |
Prognostic association of YB-1 expression in breast cancers: a matter of antibody.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Neoplasm; Breast Neoplasms; Cell Nucleus; Cohort Studies | 2011 |
Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression.
Topics: Alternative Splicing; Animals; Axin Protein; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expres | 2012 |
p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization.
Topics: Breast Neoplasms; Cell Line, Tumor; Endometrial Neoplasms; Female; Gonanes; Humans; Ligands; MAP Kin | 2011 |
MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumo | 2012 |
Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β.
Topics: Animals; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Circadian Rhythm; Enzyme Activation; Epit | 2012 |
Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Clone Cells; Contractile Proteins; Female; Filami | 2013 |
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation.
Topics: Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Cycle | 2003 |
Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis.
Topics: Adenocarcinoma; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cyc | 2004 |
Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo.
Topics: Biomarkers, Tumor; Biopsy; Blotting, Western; Breast Neoplasms; Cell Differentiation; Cell Line, Tum | 2004 |
Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 3; Caspas | 2005 |
SPBP is a phosphoserine-specific repressor of estrogen receptor alpha.
Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line; Cell Proliferation; Estrogen Receptor alpha; Femal | 2005 |
Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chlorocebus aethiop | 2005 |
Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; | 2006 |
Phosphorylation of ERalpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERalpha phosphorylation in breast cancer progression.
Topics: Biomarkers, Tumor; Breast Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Estrogen Recept | 2006 |
Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Gene Expression Regulation, Neoplastic; Gl | 2006 |
DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.
Topics: Breast Neoplasms; Dual-Specificity Phosphatases; Estradiol; Estrogen Receptor alpha; Female; HeLa Ce | 2007 |
Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation.
Topics: Actinin; Animals; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell | 2008 |
Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.
Topics: Animals; Breast Neoplasms; Casein Kinase II; Cells, Cultured; Estradiol; Moths; Neoplasms, Hormone-D | 1994 |
Phosphorylation of A 27-kDa protein correlates with survival of protein-synthesis-inhibited MCF-7 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Carcinoma; Cell S | 1997 |
Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Breast Neoplasms; Cell L | 1999 |
Dephosphorylation of p53 at Ser20 after cellular exposure to low levels of non-ionizing radiation.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Epitopes; Female; Humans; Nuclear Proteins; Phosphorylatio | 1999 |
Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome.
Topics: Acetylcysteine; Breast Neoplasms; Consensus Sequence; Cysteine Endopeptidases; Down-Regulation; Enzy | 2000 |
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.
Topics: Animals; Antibodies, Monoclonal; Becaplermin; Breast Neoplasms; Cells, Cultured; Colforsin; Epiderma | 2001 |
Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Binding Sites; Breast Neoplasms; Cell Line; | 2001 |
Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.
Topics: Adenocarcinoma; Breast Neoplasms; COUP Transcription Factor I; DNA; DNA-Binding Proteins; Enzyme Inh | 2002 |
Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474.
Topics: Blood; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Phosphorylation; | 1990 |
Tumor necrosis factor signal transduction. Tissue-specific serine phosphorylation of a 26-kDa cytosolic protein.
Topics: Breast Neoplasms; Cell Differentiation; Cell Division; Cytosol; Electrophoresis, Polyacrylamide Gel; | 1989 |