phosphoserine has been researched along with Ataxia Telangiectasia in 9 studies
Phosphoserine: The phosphoric acid ester of serine.
Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine does not inhibit Chk2/Cds1 activity directly, but rather, blocks the activation of Chk2/Cds1 by inhibiting ATM kinase activity." | 1.31 | Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. ( Chaturvedi, P; Johanson, RA; Khanna, KK; Mattern, MR; Mishra, R; Scott, SP; Spring, K; Winkler, JD; Zhou, BB, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golding, SE | 1 |
| Rosenberg, E | 1 |
| Valerie, N | 1 |
| Hussaini, I | 1 |
| Frigerio, M | 1 |
| Cockcroft, XF | 1 |
| Chong, WY | 1 |
| Hummersone, M | 1 |
| Rigoreau, L | 1 |
| Menear, KA | 1 |
| O'Connor, MJ | 1 |
| Povirk, LF | 1 |
| van Meter, T | 1 |
| Valerie, K | 1 |
| Hofseth, LJ | 1 |
| Saito, S | 1 |
| Hussain, SP | 1 |
| Espey, MG | 1 |
| Miranda, KM | 1 |
| Araki, Y | 1 |
| Jhappan, C | 1 |
| Higashimoto, Y | 1 |
| He, P | 1 |
| Linke, SP | 1 |
| Quezado, MM | 1 |
| Zurer, I | 1 |
| Rotter, V | 1 |
| Wink, DA | 1 |
| Appella, E | 1 |
| Harris, CC | 1 |
| Horejsí, Z | 1 |
| Falck, J | 1 |
| Bakkenist, CJ | 1 |
| Kastan, MB | 2 |
| Lukas, J | 1 |
| Bartek, J | 1 |
| Lavin, MF | 1 |
| Scott, SP | 2 |
| Kozlov, S | 1 |
| Gueven, N | 1 |
| Oricchio, E | 1 |
| Saladino, C | 1 |
| Iacovelli, S | 1 |
| Soddu, S | 1 |
| Cundari, E | 1 |
| Zhou, BB | 1 |
| Chaturvedi, P | 1 |
| Spring, K | 1 |
| Johanson, RA | 1 |
| Mishra, R | 1 |
| Mattern, MR | 1 |
| Winkler, JD | 1 |
| Khanna, KK | 1 |
| Chen, MJ | 1 |
| Lin, YT | 1 |
| Lieberman, HB | 1 |
| Chen, G | 1 |
| Lee, EY | 1 |
| Miyakoda, M | 1 |
| Suzuki, K | 1 |
| Kodama, S | 1 |
| Watanabe, M | 1 |
| Taniguchi, T | 1 |
| Garcia-Higuera, I | 1 |
| Xu, B | 1 |
| Andreassen, PR | 1 |
| Gregory, RC | 1 |
| Kim, ST | 1 |
| Lane, WS | 1 |
| D'Andrea, AD | 1 |
9 other studies available for phosphoserine and Ataxia Telangiectasia
| Article | Year |
|---|---|
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Movement; C | 2009 |
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation.
Topics: Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Cycle | 2003 |
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; C | 2004 |
Analyzing the regulation and function of ATM.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cloning, Molecul | 2004 |
ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Centr | 2006 |
Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Caffeine; cdc25 Phosphatases; Cell Cy | 2000 |
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; DNA- | 2001 |
Activation of ATM and phosphorylation of p53 by heat shock.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell | 2002 |
Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Trans | 2002 |