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phosphoserine and Aging

phosphoserine has been researched along with Aging in 23 studies

Phosphoserine: The phosphoric acid ester of serine.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Thus, to the extent that somatodendritic DA release affects behavior, TH regulation in the midbrain may be critical for DA bioavailability to influence behavior."1.38Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. ( Pruett, BS; Salvatore, MF, 2012)
" Growth factors increase locomotor activity in both PD and aging models and increase DA bioavailability and ser31 TH phosphorylation in SN, suggesting that ser31 TH phosphorylation status in the SN, not striatum, regulates DA bioavailability necessary for locomotor activity."1.35Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation. ( Dempsey, C; Pruett, BS; Salvatore, MF; Spann, SL, 2009)
"Together, these results show ser31 TH phosphorylation regulates DA bioavailability in intact neuropil, its status in the SN may regulate locomotor activity generation, and it may represent an accurate target for treating locomotor deficiency."1.35Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation. ( Dempsey, C; Pruett, BS; Salvatore, MF; Spann, SL, 2009)
"The neuropathological hallmarks of Alzheimer's disease and other tauopathies include senile plaques and/or neurofibrillary tangles."1.32Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. ( Bing, G; Bronson, R; Huang, HK; Hunter, T; Li, X; Liou, YC; Lu, KP; Ryo, A; Sun, A; Uchida, T; Yu, ZX; Zhou, XZ, 2003)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's5 (21.74)29.6817
2010's12 (52.17)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Sengupta, DC1
Lantz, CL1
Rumi, MAK1
Quinlan, EM1
Wang, Z1
Su, D1
Sun, Z1
Liu, S1
Sun, L1
Li, Q1
Guan, L1
Liu, Y2
Ma, X1
Hu, S1
Ludwik, KA1
Sandusky, ZM1
Stauffer, KM1
Li, Y1
Boyd, KL1
O'Doherty, GA1
Stricker, TP1
Lannigan, DA1
Batchu, SN1
Yerra, VG1
Advani, SL1
Klein, T1
Advani, A1
Calvo, B1
Thornton, TM1
Rincon, M1
Tranque, P1
Fernandez, M1
Chen, W1
Liu, N1
Zhang, H2
Qiao, J1
Jia, W1
Zhu, S1
Mao, Z1
Kang, J1
Hou, X1
Fiesel, FC1
Truban, D1
Castanedes Casey, M1
Lin, WL1
Soto, AI1
Tacik, P1
Rousseau, LG1
Diehl, NN1
Heckman, MG1
Lorenzo-Betancor, O1
Ferrer, I1
Arbelo, JM1
Steele, JC1
Farrer, MJ1
Cornejo-Olivas, M1
Torres, L1
Mata, IF1
Graff-Radford, NR1
Wszolek, ZK1
Ross, OA1
Murray, ME1
Dickson, DW1
Springer, W1
Seo, S1
Mathison, A1
Grzenda, A1
Podratz, J1
Calvo, E1
Brimijoin, S1
Windebank, A1
Iovanna, J1
Lomberk, G1
Urrutia, R1
Núñez-Santana, FL1
Oh, MM1
Antion, MD1
Lee, A1
Hell, JW1
Disterhoft, JF1
Qi, GJ1
Chen, Q1
Chen, LJ1
Shu, Y1
Bu, LL1
Shao, XY1
Zhang, P1
Jiao, FJ1
Shi, J1
Tian, B1
Luo, X1
Ribeiro, M1
Bray, ER1
Lee, DH1
Yungher, BJ1
Mehta, ST1
Thakor, KA1
Diaz, F1
Lee, JK1
Moraes, CT1
Bixby, JL1
Lemmon, VP1
Park, KK1
Arif, A1
Terenzi, F1
Potdar, AA1
Jia, J1
Sacks, J1
China, A1
Halawani, D1
Vasu, K1
Li, X2
Brown, JM1
Chen, J1
Kozma, SC1
Thomas, G1
Fox, PL1
Henson, SM1
Franzese, O1
Macaulay, R1
Libri, V1
Azevedo, RI1
Kiani-Alikhan, S1
Plunkett, FJ1
Masters, JE1
Jackson, S1
Griffiths, SJ1
Pircher, HP1
Soares, MV1
Akbar, AN1
Salvatore, MF2
Pruett, BS2
Spann, SL1
Dempsey, C1
Sarma, S1
Li, N1
van Oort, RJ1
Reynolds, C1
Skapura, DG1
Wehrens, XH1
Sofola, O1
Kerr, F1
Rogers, I1
Killick, R1
Augustin, H1
Gandy, C1
Allen, MJ1
Hardy, J1
Lovestone, S1
Partridge, L1
Wiley, LA1
Rajagopal, R1
Dattilo, LK1
Beebe, DC1
Liou, YC1
Sun, A1
Ryo, A1
Zhou, XZ1
Yu, ZX1
Huang, HK1
Uchida, T1
Bronson, R1
Bing, G1
Hunter, T1
Lu, KP1
Hirai, Y1
Fujita, SC1
Iwatsubo, T1
Hasegawa, M1
Stefani, A1
Spadoni, F1
Bernardi, G1
Cloos, PA1
Jensen, AL1
McKee, MD1
Nanci, A1
Landis, WJ1
Gotoh, Y1
Gerstenfeld, LC1
Glimcher, MJ1

Other Studies

23 other studies available for phosphoserine and Aging

ArticleYear
17α Estradiol promotes plasticity of spared inputs in the adult amblyopic visual cortex.
    Scientific reports, 2019, 12-13, Volume: 9, Issue:1

    Topics: Aging; Amblyopia; Animals; Biomarkers; Disks Large Homolog 4 Protein; Estradiol; Evoked Potentials,

2019
MDM2 phosphorylation mediates H
    Biochemical and biophysical research communications, 2020, 07-12, Volume: 528, Issue:1

    Topics: Aging; Apoptosis; Cataract; Cell Line; Epithelial Cells; Female; Humans; Hydrogen Peroxide; Lens, Cr

2020
RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha.
    Cell reports, 2020, 07-21, Volume: 32, Issue:3

    Topics: Aging; Animals; Breast; Epithelial Cell Adhesion Molecule; Epithelium; Estrogen Receptor alpha; Estr

2020
The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Directly Enhances the Contractile Recovery of Mouse Hearts at a Concentration Equivalent to that Achieved with Standard Dosing in Humans.
    International journal of molecular sciences, 2020, Aug-11, Volume: 21, Issue:16

    Topics: Aging; Animals; Calcium Signaling; Diabetes Mellitus, Experimental; Diet, High-Fat; Dipeptidyl-Pepti

2020
Regulation of GSK3β by Ser
    Molecular neurobiology, 2021, Volume: 58, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Cell Nucleus; Cells, Cultured; DNA Damage; Glyc

2021
Sirt6 Promotes DNA End Joining in iPSCs Derived from Old Mice.
    Cell reports, 2017, 03-21, Volume: 18, Issue:12

    Topics: Aging; Animals; Cellular Reprogramming; DNA End-Joining Repair; DNA-Activated Protein Kinase; DNA-Bi

2017
Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease.
    Autophagy, 2018, Volume: 14, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; alpha-Synuclein; Biomarkers; Brain; Cohort Studies; Female; HeLa Cel

2018
Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway.
    Scientific reports, 2018, 10-10, Volume: 8, Issue:1

    Topics: Aging; Amino Acid Sequence; Animals; Cell Differentiation; Chromobox Protein Homolog 5; Chromosomal

2018
Surface L-type Ca2+ channel expression levels are increased in aged hippocampus.
    Aging cell, 2014, Volume: 13, Issue:1

    Topics: Aging; Animals; Antibody Specificity; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Den

2014
Phosphorylation of Connexin 43 by Cdk5 Modulates Neuronal Migration During Embryonic Brain Development.
    Molecular neurobiology, 2016, Volume: 53, Issue:5

    Topics: Aging; Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Brain; Cell Membrane; Cell Movement;

2016
Enhanced Transcriptional Activity and Mitochondrial Localization of STAT3 Co-induce Axon Regrowth in the Adult Central Nervous System.
    Cell reports, 2016, Apr-12, Volume: 15, Issue:2

    Topics: Adenosine Triphosphate; Aging; Animals; Axons; Central Nervous System; Ciliary Neurotrophic Factor;

2016
EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
    Nature, 2017, 02-16, Volume: 542, Issue:7641

    Topics: Adaptor Proteins, Signal Transducing; Adipocytes; Adiposity; Aging; Amino Acyl-tRNA Synthetases; Ani

2017
KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.
    Blood, 2009, Jun-25, Volume: 113, Issue:26

    Topics: Adult; Aged; Aging; Cadherins; CD28 Antigens; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell

2009
Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation.
    PloS one, 2009, Dec-23, Volume: 4, Issue:12

    Topics: Aging; Animals; Biological Availability; Dopamine; Longevity; Motor Activity; Phosphorylation; Phosp

2009
Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jul-20, Volume: 107, Issue:29

    Topics: Aging; Animals; Calcium; Cardiomyopathies; Cyclic AMP-Dependent Protein Kinases; Death, Sudden; Fibr

2010
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.
    PLoS genetics, 2010, Sep-02, Volume: 6, Issue:9

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Drosophil

2010
The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.
    Disease models & mechanisms, 2011, Volume: 4, Issue:4

    Topics: Activin Receptors, Type I; Aging; Animals; Apoptosis; Biomarkers; Bone Morphogenetic Protein Recepto

2011
Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Aging; Animals; Dendrites; Dopamine; Hydrazines; Levodopa; Male; Neostriatum; Neural Pathways; Nucle

2012
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.
    Nature, 2003, Jul-31, Volume: 424, Issue:6948

    Topics: Aging; Alzheimer Disease; Amino Acid Motifs; Animals; Behavior, Animal; Gene Deletion; Gene Expressi

2003
Phosphorylated alpha-synuclein in normal mouse brain.
    FEBS letters, 2004, Aug-13, Volume: 572, Issue:1-3

    Topics: Aging; alpha-Synuclein; Animals; Brain; Cerebral Cortex; Corpus Striatum; Hippocampus; Male; Mice; M

2004
Group III metabotropic glutamate receptor agonists modulate high voltage-activated Ca2+ currents in pyramidal neurons of the adult rat.
    Experimental brain research, 1998, Volume: 119, Issue:2

    Topics: Aging; Aminobutyrates; Animals; Calcium; Calcium Channels; Electric Conductivity; Excitatory Amino A

1998
Age-related de-phosphorylation of proteins in dentin: a biological tool for assessment of protein age.
    Biogerontology, 2000, Volume: 1, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Amino Acids; Dentin; Female; Humans; Male; Middle Aged; Phosphoprote

2000
Developmental appearance and ultrastructural immunolocalization of a major 66 kDa phosphoprotein in embryonic and post-natal chicken bone.
    The Anatomical record, 1990, Volume: 228, Issue:1

    Topics: Aging; Animals; Blotting, Western; Bone and Bones; Bone Development; Calcification, Physiologic; Chi

1990