phosphorylethanolamine has been researched along with Aging in 13 studies
phosphorylethanolamine: RN given refers to parent cpd; structure
O-phosphoethanolamine : The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The regional neurochemical profile evolution indicated that aging induces general modifications of neurotransmission processes (reduced GABA and glutamate), primary energy metabolism (altered glucose, alanine, and lactate) and turnover of lipid membranes (modification of choline-containing compounds and phosphorylethanolamine), which are all probably involved in the frequently observed age-related cognitive decline." | 3.80 | Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by 1H magnetic resonance spectroscopy. ( Do, KQ; Duarte, JM; Gruetter, R, 2014) |
| "Preliminary studies in Alzheimer's disease have demonstrated elevated levels of phosphomonoesters and phosphodiesters in the areas of Alzheimer's brain which exhibit neuropathological changes." | 2.37 | 31P nuclear magnetic resonance (NMR) spectroscopy of brain in aging and Alzheimer's disease. ( Panchalingam, K; Pettegrew, JW; Post, JF; Withers, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Grapentine, S | 1 |
| Singh, RK | 1 |
| Basu, P | 1 |
| Sivanesan, S | 1 |
| Mattos, G | 1 |
| Oresajo, O | 1 |
| Cheema, J | 1 |
| Demeke, W | 1 |
| Dolinsky, VW | 1 |
| Bakovic, M | 1 |
| Gonzalez-Covarrubias, V | 1 |
| Beekman, M | 1 |
| Uh, HW | 1 |
| Dane, A | 1 |
| Troost, J | 1 |
| Paliukhovich, I | 1 |
| van der Kloet, FM | 1 |
| Houwing-Duistermaat, J | 1 |
| Vreeken, RJ | 1 |
| Hankemeier, T | 1 |
| Slagboom, EP | 1 |
| Harper, DG | 1 |
| Jensen, JE | 1 |
| Ravichandran, C | 1 |
| Sivrioglu, Y | 1 |
| Silveri, M | 1 |
| Iosifescu, DV | 1 |
| Renshaw, PF | 2 |
| Forester, BP | 1 |
| Duarte, JM | 1 |
| Do, KQ | 1 |
| Gruetter, R | 2 |
| Rao, R | 1 |
| Tkac, I | 1 |
| Townsend, EL | 1 |
| Georgieff, MK | 1 |
| Zelenka, PS | 1 |
| Jernigan, HM | 3 |
| Kador, PF | 1 |
| Kinoshita, JH | 1 |
| Babb, SM | 1 |
| Wald, LL | 1 |
| Cohen, BM | 1 |
| Villafuerte, RA | 1 |
| Gruber, SA | 1 |
| Yurgelun-Todd, DA | 1 |
| Van der Grond, J | 1 |
| Dijkstra, G | 1 |
| Roelofsen, B | 1 |
| Mali, WP | 1 |
| Zigler, JS | 1 |
| Pettegrew, JW | 2 |
| Kopp, SJ | 1 |
| Minshew, NJ | 1 |
| Glonek, T | 1 |
| Feliksik, JM | 1 |
| Tow, JP | 1 |
| Cohen, MM | 1 |
| Burri, R | 1 |
| Lazeyras, F | 1 |
| Aue, WP | 1 |
| Straehl, P | 1 |
| Bigler, P | 1 |
| Althaus, U | 1 |
| Herschkowitz, N | 1 |
| Withers, G | 1 |
| Panchalingam, K | 1 |
| Post, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Combination of Cytidine and Omega-3 Fatty Acids in Bipolar Disorder: Are There Additive or Synergistic Mood Stabilizing Effects?[NCT00854737] | Phase 2 | 90 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phosphorylethanolamine and Aging
| Article | Year |
|---|---|
31P nuclear magnetic resonance (NMR) spectroscopy of brain in aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Brain; Ethanolamines; Humans; Magnetic Resonance Spectroscopy; Or | 1987 |
1 trial available for phosphorylethanolamine and Aging
| Article | Year |
|---|---|
Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study.
Topics: Administration, Oral; Aged; Aging; Analysis of Variance; Brain; Brain Chemistry; Cytidine Diphosphat | 2002 |
11 other studies available for phosphorylethanolamine and Aging
| Article | Year |
|---|---|
Pcyt2 deficiency causes age-dependant development of nonalcoholic steatohepatitis and insulin resistance that could be attenuated with phosphoethanolamine.
Topics: Aging; Animals; Ethanolamines; Fatty Acids; Glucose; Insulin Resistance; Mice; Mice, Knockout; Non-a | 2022 |
Lipidomics of familial longevity.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Biomarkers; Chromatography, Liquid; Cohort Stud | 2013 |
Tissue-specific differences in brain phosphodiesters in late-life major depression.
Topics: Aged; Aged, 80 and over; Aging; Brain; Case-Control Studies; Depressive Disorder, Major; Ethanolamin | 2014 |
Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by 1H magnetic resonance spectroscopy.
Topics: Aging; Alanine; Animals; Cerebral Cortex; Cognition; Corpus Striatum; Energy Metabolism; Ethanolamin | 2014 |
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; | 2003 |
Phosphorylcholine and phosphorylethanolamine concentrations in the lens.
Topics: Aging; Animals; Cataract; Chickens; Choline; Culture Techniques; Ethanolamines; Female; Humans; Lens | 1982 |
Carrier mediated transport of choline in rat lens.
Topics: Aging; Animals; Biological Transport, Active; Choline; Culture Techniques; Ethanolamines; Lens, Crys | 1981 |
31P-NMR determination of phosphomonoesters in relation to phospholipid biosynthesis in testis of the rat at different ages.
Topics: Aging; Animals; Ethanolamines; Kinetics; Magnetic Resonance Spectroscopy; Male; Phospholipids; Phosp | 1991 |
Phosphorylcholine and phosphorylethanolamine in human and rhesus monkey lenses.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Child; Child, Preschool; Choline; Cultur | 1989 |
31P nuclear magnetic resonance studies of phosphoglyceride metabolism in developing and degenerating brain: preliminary observations.
Topics: Adult; Aged; Aging; Alzheimer Disease; Animals; Brain; Ethanolamines; Female; Glycerophosphates; Hum | 1987 |
Correlation between 31P NMR phosphomonoester and biochemically determined phosphorylethanolamine and phosphatidylethanolamine during development of the rat brain.
Topics: Aging; Animals; Brain; Ethanolamines; Female; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inb | 1988 |