phosphorylcholine has been researched along with Thyroid Neoplasms in 5 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perifosine could potently inhibit thyroid cancer cell growth when used alone, but a strong antagonism occurred between this drug and PLX4032 or AZD6244 in the inhibition of thyroid cancer cell growth with all combination index values higher than 1." | 1.38 | The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells. ( Liu, D; Liu, R; Xing, M, 2012) |
| "EphA2 protein was expressed in thyroid cancer cell lines and in benign and malignant human thyroid tumors but not in normal thyroid." | 1.38 | Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt. ( Howe, JR; Komorowski, RA; Lal, G; O'Malley, Y; Shilyansky, J; Sugg, SL; Weigel, RJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, D | 2 |
| Hou, P | 2 |
| Liu, Z | 1 |
| Wu, G | 1 |
| Xing, M | 3 |
| Bojdani, E | 1 |
| Liu, R | 1 |
| O'Malley, Y | 1 |
| Lal, G | 1 |
| Howe, JR | 1 |
| Weigel, RJ | 1 |
| Komorowski, RA | 1 |
| Shilyansky, J | 1 |
| Sugg, SL | 1 |
| Afrasiabi, E | 1 |
| Blom, T | 1 |
| Balthasar, S | 1 |
| Törnquist, K | 1 |
5 other studies available for phosphorylcholine and Thyroid Neoplasms
| Article | Year |
|---|---|
Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Humans; Mi | 2009 |
Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways.
Topics: Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Intracellular Signaling Pept | 2010 |
The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma; Cell Proliferation; Down- | 2012 |
Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt.
Topics: Adenocarcinoma, Follicular; Cell Line, Tumor; Humans; Immunoblotting; Neoplasm Invasiveness; Phospho | 2012 |
Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Movement; Cell | 2007 |