Page last updated: 2024-10-19

phosphorylcholine and Stomach Neoplasms

phosphorylcholine has been researched along with Stomach Neoplasms in 7 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
"Perifosine is a bioavailable alkylphospholipid exhibiting antitumor activity in a series of cancer types."1.39Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth. ( Guo, R; Liang, S; Liu, D; Wang, X; Xu, H; Xu, Z; Yang, L; Zhang, Z, 2013)
"Perifosine inhibits the growth of gastric cancer cells possibly through inhibition of the Akt/GSK3β/C-MYC signaling pathway-mediated down-regulation of AEG-1 that subsequently down-regulated cyclin D1."1.39AEG-1 is a target of perifosine and is over-expressed in gastric dysplasia and cancers. ( Chen, X; Huang, W; Li, P; Liang, S; Liu, D; Ma, Z; Wang, X; Yang, L; Zhai, S, 2013)
"Perifosine is an alkylphospholipid exhibiting antitumor activity as shown in both preclinical studies and clinical trials."1.39MicroRNA-27a inhibitors alone or in combination with perifosine suppress the growth of gastric cancer cells. ( Liang, S; Liu, D; Luo, X; Sun, Q; Wang, X; Xu, L; Yang, L; Zhao, X, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liang, S3
Guo, R1
Zhang, Z1
Liu, D3
Xu, H1
Xu, Z1
Wang, X3
Yang, L3
Huang, W1
Chen, X1
Ma, Z1
Zhai, S1
Li, P1
Yamada, H1
Hasegawa, Y1
Suzuki, Y1
Imai, H1
Matsuda, T1
Kimura, Y1
Toshimitsu, A1
Aoyama, Y1
Kondo, T1
Soma, D1
Kitayama, J1
Konno, T1
Ishihara, K1
Yamada, J1
Kamei, T1
Ishigami, H1
Kaisaki, S1
Nagawa, H1
Takeuchi, H1
Ueda, M1
Oyama, T1
Shimizu, Y1
Kitagawa, Y1
Busch, T1
Armacki, M1
Eiseler, T1
Joodi, G1
Temme, C1
Jansen, J1
von Wichert, G1
Omary, MB1
Spatz, J1
Seufferlein, T1
Sun, Q1
Xu, L1
Luo, X1
Zhao, X1

Reviews

1 review available for phosphorylcholine and Stomach Neoplasms

ArticleYear
Molecular diagnosis and translymphatic chemotherapy targeting sentinel lymph nodes of patients with early gastrointestinal cancers.
    Digestion, 2010, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Humans; Lymph Nodes; Lymphatic Metastasis

2010

Other Studies

6 other studies available for phosphorylcholine and Stomach Neoplasms

ArticleYear
Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth.
    Oncology reports, 2013, Volume: 29, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Pro

2013
AEG-1 is a target of perifosine and is over-expressed in gastric dysplasia and cancers.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Proliferatio

2013
Magnetic resonance imaging of tumor with a self-traceable polymer conjugated with an antibody fragment.
    Bioorganic & medicinal chemistry letters, 2015, Jul-01, Volume: 25, Issue:13

    Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Female; Humans; Immunoconjugates; Magnetic Resonance Ima

2015
Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer.
    Cancer science, 2009, Volume: 100, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Carrier

2009
Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells.
    Journal of cell science, 2012, May-01, Volume: 125, Issue:Pt 9

    Topics: Cell Line, Tumor; Cell Movement; Cytoskeleton; Epithelial Cells; Extracellular Signal-Regulated MAP

2012
MicroRNA-27a inhibitors alone or in combination with perifosine suppress the growth of gastric cancer cells.
    Molecular medicine reports, 2013, Volume: 7, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Female; G

2013