Page last updated: 2024-10-19

phosphorylcholine and Schizophrenia

phosphorylcholine has been researched along with Schizophrenia in 8 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
" Inconsistent alterations of phosphocholine (PC), phosphoethanolamine (PE), glycerophosphocholine (GPC) and glycerophosphoethanolamine (GPE) have been described in schizophrenia, which might be overcome by specific editing techniques."3.79Altered phospholipid metabolism in schizophrenia: a phosphorus 31 nuclear magnetic resonance spectroscopy study. ( Ende, G; Englisch, S; Esser, A; Meyer-Lindenberg, A; Tunc-Skarka, N; Weber-Fahr, W; Zink, M, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Yi, W1
Ji, Y1
Gao, H1
Luo, S1
Pan, R1
Song, J1
He, Y1
Li, Y1
Wu, Y1
Yan, S1
Liang, Y1
Sun, X1
Jin, X1
Mei, L1
Cheng, J1
Su, H1
Rapoport, JL1
Weber-Fahr, W1
Englisch, S1
Esser, A1
Tunc-Skarka, N1
Meyer-Lindenberg, A1
Ende, G1
Zink, M1
Lutkenhoff, ES1
van Erp, TG1
Thomas, MA1
Therman, S1
Manninen, M1
Huttunen, MO1
Kaprio, J1
Lönnqvist, J1
O'Neill, J1
Cannon, TD1
Ross, RG1
Hunter, SK1
McCarthy, L1
Beuler, J1
Hutchison, AK1
Wagner, BD1
Leonard, S1
Stevens, KE1
Freedman, R1
Potwarka, JJ1
Drost, DJ1
Williamson, PC1
Carr, T1
Canaran, G1
Rylett, WJ1
Neufeld, RW1
Fukuzako, H1
Fukuzako, T1
Hashiguchi, T1
Kodama, S1
Takigawa, M1
Fujimoto, T1
Salvadorini, F1
Galeone, F1
Marescotti, V1
Saba, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Trial of Phosphatidylcholine During Pregnancy and Infant Serum Choline Levels[NCT00332124]Phase 1351 participants (Actual)Interventional2006-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for phosphorylcholine and Schizophrenia

ArticleYear
Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
    The American journal of psychiatry, 2013, Volume: 170, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Attention; Brain; Child, Preschool; Choline; DNA Mutational

2013
A 1H-decoupled 31P chemical shift imaging study of medicated schizophrenic patients and healthy controls.
    Biological psychiatry, 1999, Mar-15, Volume: 45, Issue:6

    Topics: Adult; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Chronic Disease; Female; Humans; Magne

1999

Other Studies

6 other studies available for phosphorylcholine and Schizophrenia

ArticleYear
Effects of urban particulate matter on gut microbiome and partial schizophrenia-like symptoms in mice: Evidence from shotgun metagenomic and metabolomic profiling.
    The Science of the total environment, 2023, Jan-20, Volume: 857, Issue:Pt 1

    Topics: Animals; Dizocilpine Maleate; Estriol; Estrogens; Feces; Gastrointestinal Microbiome; Mice; Particul

2023
Prevention of schizophrenia: an impossible dream?
    The American journal of psychiatry, 2013, Volume: 170, Issue:3

    Topics: Attention; Brain; Choline; Female; Humans; Male; Neural Inhibition; Nootropic Agents; Phosphorylchol

2013
Altered phospholipid metabolism in schizophrenia: a phosphorus 31 nuclear magnetic resonance spectroscopy study.
    Psychiatry research, 2013, Dec-30, Volume: 214, Issue:3

    Topics: Adult; Antipsychotic Agents; Brain; Case-Control Studies; Cerebellum; Cerebral Cortex; Cross-Section

2013
Proton MRS in twin pairs discordant for schizophrenia.
    Molecular psychiatry, 2010, Volume: 15, Issue:3

    Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glycerylphosphorylcholine; Hippocampus; Humans; Inos

2010
Changes in levels of phosphorus metabolites in temporal lobes of drug-naive schizophrenic patients.
    The American journal of psychiatry, 1999, Volume: 156, Issue:8

    Topics: Adult; Analysis of Variance; Brief Psychiatric Rating Scale; Esters; Ethanolamines; Female; Function

1999
[Effect of CDP-choline on GH release in patients with chronic psychopathy].
    La Clinica terapeutica, 1978, Jun-30, Volume: 85, Issue:6

    Topics: Adult; Choline; Chronic Disease; Depression; Female; Growth Hormone; Humans; Male; Mental Disorders;

1978