Page last updated: 2024-10-20

phosphorylcholine and Schistosoma mansoni Infection

phosphorylcholine has been researched along with Schistosoma mansoni Infection in 6 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors."7.83Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016)
"Miltefosine (MFS) is an alkylphosphocholine used for the local treatment of cutaneous metastases of breast cancer and oral therapy of visceral leishmaniasis."5.42Miltefosine Lipid Nanocapsules for Single Dose Oral Treatment of Schistosomiasis Mansoni: A Preclinical Study. ( Amer, EI; Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2015)
"A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors."3.83Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016)
"Miltefosine (MFS) is an alkylphosphocholine used for the local treatment of cutaneous metastases of breast cancer and oral therapy of visceral leishmaniasis."1.42Miltefosine Lipid Nanocapsules for Single Dose Oral Treatment of Schistosomiasis Mansoni: A Preclinical Study. ( Amer, EI; Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2015)
"Edelfosine oral treatment also showed in vivo schistosomicidal activity and decreased significantly the egg burden in the liver, a key event in schistosomiasis."1.40In vitro and in vivo anti-schistosomal activity of the alkylphospholipid analog edelfosine. ( Dakir, EL; Dakir, el H; López-Abán, J; Mollinedo, F; Muro, A; Varela-M, RE; Yepes, E, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Eissa, MM5
El-Azzouni, MZ5
El-Khordagui, LK4
Abdel Bary, A2
El-Moslemany, RM4
Abdel Salam, SA2
Yepes, E1
Varela-M, RE1
López-Abán, J1
Dakir, el H1
Dakir, EL1
Mollinedo, F1
Muro, A1
Ramadan, AA2
Amer, EI2
Baddour, NM1

Other Studies

6 other studies available for phosphorylcholine and Schistosoma mansoni Infection

ArticleYear
Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni.
    Parasites & vectors, 2020, Sep-15, Volume: 13, Issue:1

    Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Combinations; Drug Compounding; Female;

2020
Evaluation of prophylactic efficacy and safety of praziquantel-miltefosine nanocombination in experimental Schistosomiasis mansoni.
    Acta tropica, 2020, Volume: 212

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Carriers; Drug Combinations; Granuloma; Lipids;

2020
In vitro and in vivo anti-schistosomal activity of the alkylphospholipid analog edelfosine.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Apoptosis; Female; Mice; Phospholipid Ethers;

2014
Miltefosine Lipid Nanocapsules for Single Dose Oral Treatment of Schistosomiasis Mansoni: A Preclinical Study.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Hemolysis; Liver;

2015
Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni.
    Acta tropica, 2016, Volume: 159

    Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Repositioning; Granuloma; Liver; Mice; N

2016
Miltefosine, a promising novel agent for schistosomiasis mansoni.
    International journal for parasitology, 2011, Volume: 41, Issue:2

    Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Liver; Male; Mice; Microscopy, Electron, Scan

2011