Page last updated: 2024-10-19

phosphorylcholine and Otitis Media

phosphorylcholine has been researched along with Otitis Media in 12 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.

Research Excerpts

ExcerptRelevanceReference
"A prospective randomized double-blind controlled trial in children with recurrent acute otitis media and chronic otitis media with effusion; 240 children were randomized to receive a phosphorylcholine-coated tube in one ear and an uncoated tube in the other."9.15A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media. ( Corsten, G; Hong, P; Johnson, LB; Smith, N, 2011)
"A prospective randomized double-blind controlled trial in children with recurrent acute otitis media and chronic otitis media with effusion; 240 children were randomized to receive a phosphorylcholine-coated tube in one ear and an uncoated tube in the other."5.15A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media. ( Corsten, G; Hong, P; Johnson, LB; Smith, N, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's5 (41.67)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Kadowaki, Y1
Hirano, T1
Fujita, K1
Kawano, T1
Matsunaga, T1
Yoshinaga, K1
Suzuki, M1
Langereis, JD1
van Dongen, TM1
Stol, K1
Venekamp, RP1
Schilder, AG1
Hermans, PW1
Armbruster, CE1
Hong, W3
Pang, B2
Dew, KE1
Juneau, RA1
Byrd, MS1
Love, CF1
Kock, ND1
Swords, WE3
Hong, P1
Smith, N1
Johnson, LB1
Corsten, G1
Johnson, RW1
McGillivary, G1
Denoël, P1
Poolman, J1
Bakaletz, LO2
Månsson, M1
Hood, DW1
Moxon, ER1
Schweda, EK1
Mason, K1
Jurcisek, J1
Novotny, L1
West-Barnette, S1
Andersson, B3
Fogh, A1
Jørgensen, F2
Larsson, S1
Leffler, H1
Magnusson, G1
Nylén, O3
Südow, C1
Svanborg Edén, C1
Rosen, IA1
Håkansson, A1
Aniansson, G1
Hansson, C1
Sabharwal, H1
Svanborg, C1
Tong, HH1
Blue, LE1
James, MA1
Chen, YP1
DeMaria, TF1
Hanson, LA1
Edén, CS1

Trials

2 trials available for phosphorylcholine and Otitis Media

ArticleYear
A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media.
    The Laryngoscope, 2011, Volume: 121, Issue:1

    Topics: Acute Disease; Child; Child, Preschool; Chronic Disease; Coated Materials, Biocompatible; Double-Bli

2011
Gamma-globulin treatment of recurrent acute otitis media in children.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:6

    Topics: Acute Disease; Female; Follow-Up Studies; Humans; Immunization, Passive; Immunoglobulin A, Secretory

1990

Other Studies

10 other studies available for phosphorylcholine and Otitis Media

ArticleYear
Phase variation with altering phosphorylcholine expression of nontypeable Haemophilus influenzae affects bacteria clearance and mucosal immune response in the middle ear and nasopharynx.
    Auris, nasus, larynx, 2021, Volume: 48, Issue:1

    Topics: Animals; C-Reactive Protein; Cytokines; Disease Models, Animal; Ear, Middle; Haemophilus Infections;

2021
Resistance to complement-mediated killing and IgM binding to non-typeable Haemophilus influenzae is not altered when ascending from the nasopharynx to the middle ears in children with otitis media.
    Medical microbiology and immunology, 2013, Volume: 202, Issue:6

    Topics: Antibodies, Bacterial; Child; Child, Preschool; Cohort Studies; Complement System Proteins; DNA, Bac

2013
LuxS promotes biofilm maturation and persistence of nontypeable haemophilus influenzae in vivo via modulation of lipooligosaccharides on the bacterial surface.
    Infection and immunity, 2009, Volume: 77, Issue:9

    Topics: Animals; Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Chinchilla; Haemophilus influenzae; Hom

2009
Abrogation of nontypeable Haemophilus influenzae protein D function reduces phosphorylcholine decoration, adherence to airway epithelial cells, and fitness in a chinchilla model of otitis media.
    Vaccine, 2011, Feb-01, Volume: 29, Issue:6

    Topics: Animals; Bacterial Adhesion; Bacterial Proteins; Carrier Proteins; Chinchilla; Epithelial Cells; Hae

2011
Structural characterization of a novel branching pattern in the lipopolysaccharide from nontypeable Haemophilus influenzae.
    European journal of biochemistry, 2003, Volume: 270, Issue:14

    Topics: Acetylation; Carbohydrate Conformation; Carbohydrate Sequence; Glycosylation; Haemophilus influenzae

2003
Phosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media.
    Infection and immunity, 2007, Volume: 75, Issue:2

    Topics: Animals; Bacterial Proteins; Biofilms; Chinchilla; Colony Count, Microbial; Diacylglycerol Cholineph

2007
Phosphorylcholine expression by nontypeable Haemophilus influenzae correlates with maturation of biofilm communities in vitro and in vivo.
    Journal of bacteriology, 2007, Volume: 189, Issue:22

    Topics: Animals; Bacterial Proteins; Bacteriological Techniques; Biofilms; Chinchilla; Gene Expression Regul

2007
Attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells in vitro--mechanism of binding.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1984, Volume: 92, Issue:3

    Topics: Adhesiveness; Fibronectins; Humans; Immunoglobulins; Mucous Membrane; Otitis Media; Pharynx; Phospho

1984
Antibodies to pneumococcal polysaccharides in human milk: lack of relationship to colonization and acute otitis media.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:6

    Topics: Adult; Animals; Antibodies, Bacterial; Bacterial Capsules; Breast Feeding; Female; Humans; Infant; I

1996
Evaluation of phase variation of nontypeable Haemophilus influenzae lipooligosaccharide during nasopharyngeal colonization and development of otitis media in the chinchilla model.
    Infection and immunity, 2000, Volume: 68, Issue:8

    Topics: Animals; Antigens, Bacterial; Bacterial Proteins; Chinchilla; Disease Models, Animal; Genes, Bacteri

2000