phosphorylcholine has been researched along with Niemann-Pick Diseases in 15 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Iwahori, A | 1 |
| Maekawa, M | 1 |
| Narita, A | 1 |
| Kato, A | 1 |
| Sato, T | 1 |
| Ogura, J | 1 |
| Sato, Y | 1 |
| Kikuchi, M | 1 |
| Noguchi, A | 1 |
| Higaki, K | 1 |
| Okuyama, T | 1 |
| Takahashi, T | 1 |
| Eto, Y | 1 |
| Mano, N | 1 |
| Zhou, YF | 1 |
| Metcalf, MC | 1 |
| Garman, SC | 1 |
| Edmunds, T | 1 |
| Qiu, H | 1 |
| Wei, RR | 1 |
| Lansmann, S | 1 |
| Schuette, CG | 1 |
| Bartelsen, O | 1 |
| Hoernschemeyer, J | 1 |
| Linke, T | 1 |
| Weisgerber, J | 1 |
| Sandhoff, K | 1 |
| Harzer, K | 2 |
| Rolfs, A | 1 |
| Bauer, P | 1 |
| Zschiesche, M | 2 |
| Mengel, E | 2 |
| Backes, J | 1 |
| Kustermann-Kuhn, B | 1 |
| Bruchelt, G | 1 |
| van Diggelen, OP | 2 |
| Mayrhofer, H | 1 |
| Krägeloh-Mann, I | 1 |
| Voznyi, YV | 1 |
| Keulemans, JL | 1 |
| Schoonderwoerd, K | 1 |
| Ledvinova, J | 1 |
| Santer, R | 1 |
| Fujiwaki, T | 1 |
| Tasaka, M | 1 |
| Yamaguchi, S | 1 |
| Gal, AE | 2 |
| Brady, RO | 2 |
| Barranger, JA | 1 |
| Pentchev, PG | 2 |
| Berger, A | 1 |
| Rosenthal, D | 1 |
| Spiegel, S | 1 |
| Ohno, K | 1 |
| Rodriguez-Lafrasse, C | 1 |
| Vanier, MT | 1 |
| Jansen, SM | 1 |
| Groener, JE | 1 |
| Bax, W | 1 |
| Suter, A | 1 |
| Saftig, P | 1 |
| Somerharju, P | 1 |
| Poorthuis, BJ | 1 |
| Patrick, AD | 1 |
| Young, E | 1 |
| Kleijer, WJ | 1 |
| Niermeijer, MF | 1 |
| Den Tandt, WR | 1 |
| Jaeken, J | 1 |
| Leroy, JG | 1 |
| Eggermont, E | 1 |
| Hibbert, SR | 1 |
| Strasberg, PM | 1 |
| Callahan, JW | 1 |
1 review available for phosphorylcholine and Niemann-Pick Diseases
| Article | Year |
|---|---|
[Niemann-Pick disease types A and B].
Topics: Animals; Cell Differentiation; Ceramides; Glycoproteins; Humans; Lysosomes; Mice; Mutation; Niemann- | 1995 |
14 other studies available for phosphorylcholine and Niemann-Pick Diseases
| Article | Year |
|---|---|
Development of a Diagnostic Screening Strategy for Niemann-Pick Diseases Based on Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analyses of N-Palmitoyl-O-phosphocholine-serine and Sphingosylphosphorylcholine.
Topics: Chromatography, Liquid; Humans; Niemann-Pick Diseases; Phosphatidylcholines; Phosphorylcholine; Sphi | 2020 |
Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; HEK293 Cells; Humans; | 2016 |
Human acid sphingomyelinase.
Topics: Amino Acid Sequence; Ceramides; Disulfides; Glycosylation; Humans; Indicators and Reagents; Molecula | 2003 |
Niemann-Pick disease type A and B are clinically but also enzymatically heterogeneous: pitfall in the laboratory diagnosis of sphingomyelinase deficiency associated with the mutation Q292 K.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Enzyme Tests; Diagnostic Errors; Humans; | 2003 |
A new fluorimetric enzyme assay for the diagnosis of Niemann-Pick A/B, with specificity of natural sphingomyelinase substrate.
Topics: Blood Chemical Analysis; Ceramides; Chemistry, Clinical; Clinical Enzyme Tests; Diagnosis, Different | 2005 |
Quantitative evaluation of sphingomyelin and glucosylceramide using matrix-assisted laser desorption ionization time-of-flight mass spectrometry with sphingosylphosphorylcholine as an internal standard. Practical application to tissues from patients with
Topics: Child, Preschool; Gaucher Disease; Glucosylceramides; Humans; Liver; Niemann-Pick Diseases; Phosphor | 2008 |
The diagnosis of type A and type B Niemann Pick disease and detection of carriers using leukocytes and a chromogenic analogue of sphingomyelin.
Topics: Choline; Genetic Carrier Screening; Humans; Leukocytes; Niemann-Pick Diseases; Nitrophenols; Phospho | 1980 |
Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1.
Topics: 3T3 Cells; Animals; Base Sequence; Binding Sites; Cell Division; Cell Nucleus; DNA; DNA-Binding Prot | 1995 |
Sphingosylphosphorylcholine in Niemann-Pick disease brain: accumulation in type A but not in type B.
Topics: Brain; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Liver; Niemann-Pick D | 1999 |
Biosynthesis of phosphatidylcholine from a phosphocholine precursor pool derived from the late endosomal/lysosomal degradation of sphingomyelin.
Topics: Alkaline Phosphatase; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Digitonin; Dos | 2001 |
Prenatal diagnosis of Niemann-Pick disease type A using chromogenic substrate.
Topics: Amniotic Fluid; Choline; Female; Fibroblasts; Humans; Niemann-Pick Diseases; Phosphorylcholine; Preg | 1977 |
A micromethod for sphingomyelinase assay using a chromogenic artificial substrate. Its use in the diagnosis of Niemann-Pick disease.
Topics: Adolescent; Child; Child, Preschool; Choline; Female; Fibroblasts; Humans; Male; Methods; Niemann-Pi | 1979 |
A practical chromogenic procedure for the detection of homozygotes and heterozygous carriers of Niemann-Pick disease.
Topics: Amniotic Fluid; Cells, Cultured; Cerebrosides; Choline; Clinical Enzyme Tests; Fibroblasts; Glucosyl | 1975 |
Lysosphingolipids and mitochondrial function. II. Deleterious effects of sphingosylphosphorylcholine.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Choline; Erythrocytes; Hemolysi | 1988 |