phosphorylcholine has been researched along with Lymph Node Metastasis in 6 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the response rate and toxicity of the alkylphosphocholine analogue, perifosine, in patients with metastatic or recurrent malignant melanoma." | 9.11 | Phase II study of perifosine in previously untreated patients with metastatic melanoma. ( Baetz, T; Belanger, K; Davis, M; Eisenhauer, E; Ernst, DS; Lohmann, R; Smylie, M; Wainman, N, 2005) |
| "To assess the response rate and toxicity of the alkylphosphocholine analogue, perifosine, in patients with metastatic or recurrent malignant melanoma." | 5.11 | Phase II study of perifosine in previously untreated patients with metastatic melanoma. ( Baetz, T; Belanger, K; Davis, M; Eisenhauer, E; Ernst, DS; Lohmann, R; Smylie, M; Wainman, N, 2005) |
| "The treatment of localized colorectal cancer (CRC) depends on resection of the primary tumor with adequate margins and sufficient lymph node sampling." | 1.40 | Phospholipid ether analogs for the detection of colorectal tumors. ( Albrecht, DM; Clipson, L; Deming, DA; Grudzinski, JP; Halberg, RB; Hall, LT; Leystra, AA; Lubner, SJ; Maher, ME; Matkowskyj, KA; Washington, MK; Weichert, JP, 2014) |
| "Perifosine is a bioavailable alkylphospholipid exhibiting antitumor activity in a series of cancer types." | 1.39 | Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth. ( Guo, R; Liang, S; Liu, D; Wang, X; Xu, H; Xu, Z; Yang, L; Zhang, Z, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, S | 1 |
| Guo, R | 1 |
| Zhang, Z | 1 |
| Liu, D | 1 |
| Xu, H | 1 |
| Xu, Z | 1 |
| Wang, X | 1 |
| Yang, L | 1 |
| Oyama, T | 2 |
| Takeuchi, H | 2 |
| Matsuda, S | 1 |
| Ozawa, S | 1 |
| Kitajima, M | 1 |
| Kitagawa, Y | 2 |
| Deming, DA | 1 |
| Maher, ME | 1 |
| Leystra, AA | 1 |
| Grudzinski, JP | 1 |
| Clipson, L | 1 |
| Albrecht, DM | 1 |
| Washington, MK | 1 |
| Matkowskyj, KA | 1 |
| Hall, LT | 1 |
| Lubner, SJ | 1 |
| Weichert, JP | 1 |
| Halberg, RB | 1 |
| Ueda, M | 1 |
| Shimizu, Y | 1 |
| Ernst, DS | 1 |
| Eisenhauer, E | 1 |
| Wainman, N | 1 |
| Davis, M | 1 |
| Lohmann, R | 1 |
| Baetz, T | 1 |
| Belanger, K | 1 |
| Smylie, M | 1 |
| Marsh, Rde W | 1 |
| Rocha Lima, CM | 1 |
| Levy, DE | 1 |
| Mitchell, EP | 1 |
| Rowland, KM | 1 |
| Benson, AB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study Of Perifosine (D-21266) In Previously Untreated Patients With Metastatic Or Recurrent Malignant Melanoma[NCT00053781] | Phase 2 | 18 participants (Actual) | Interventional | 2003-06-20 | Completed | ||
| Phase II Trial Of Perifosine In Locally Advanced, Unresectable Or Metastatic Pancreatic Adenocarcinoma[NCT00059982] | Phase 2 | 0 participants | Interventional | 2003-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phosphorylcholine and Lymph Node Metastasis
| Article | Year |
|---|---|
Molecular diagnosis and translymphatic chemotherapy targeting sentinel lymph nodes of patients with early gastrointestinal cancers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Humans; Lymph Nodes; Lymphatic Metastasis | 2010 |
2 trials available for phosphorylcholine and Lymph Node Metastasis
| Article | Year |
|---|---|
Phase II study of perifosine in previously untreated patients with metastatic melanoma.
Topics: Adult; Aged; Aged, 80 and over; Arthralgia; Chondrocalcinosis; Female; Humans; Liver Neoplasms; Lung | 2005 |
A phase II trial of perifosine in locally advanced, unresectable, or metastatic pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antiemetics; Child; Disease Progression; Drug Administra | 2007 |
3 other studies available for phosphorylcholine and Lymph Node Metastasis
| Article | Year |
|---|---|
Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth.
Topics: Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Pro | 2013 |
Translymphatic chemotherapy targeting sentinel lymph nodes using a novel phospholipid polymer-Paclitaxel conjugate.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Line, Tumor; Cell Survival; Disease Mo | 2014 |
Phospholipid ether analogs for the detection of colorectal tumors.
Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Female; Humans; Indoles; Intestinal Neoplasms; Iodobe | 2014 |