Page last updated: 2024-10-19

phosphorylcholine and Lung Diseases

phosphorylcholine has been researched along with Lung Diseases in 21 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Lung Diseases: Pathological processes involving any part of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary hemorrhage was present in 55% of 159 infants undergoing autopsy; the incidence was not different in infants treated with surfactant or air placebo."2.67Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group. ( Derleth, D; Finer, N; Long, W; McMurray, B; Mullett, M; Peliowski, A; Sankaran, K; van Houten, J; Walker, D; Wold, D, 1992)
"Pulmonary hemorrhage was defined by an onset of bright red blood from the endotracheal tube in quantities that resulted in increased ventilatory support and a new infiltrate on a chest radiograph."1.29Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study. ( Buck, R; Garland, J; Weinberg, M, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (95.24)18.2507
2000's0 (0.00)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bahadue, FL1
Soll, R1
Strüber, M1
Cremer, J1
Harringer, W1
Hirt, SW1
Costard-Jäckle, A1
Haverich, A1
Huang, YC2
Sane, AC1
Simonson, SG1
Fawcett, TA1
Moon, RE1
Fracica, PJ2
Menache, MG1
Piantadosi, CA2
Young, SL2
Duhaylongsod, FG1
Welty-Wolf, KE1
Crapo, JD1
Findlay, RD1
Taeusch, HW1
David-Cu, R1
Walther, FJ2
Mullett, M2
Schumacher, R1
Sundell, H1
Easa, D2
Long, W8
Sell, M1
Cotton, R1
Hirata, T1
Guthrie, R1
LeBlanc, M1
Mammel, M1
Gerdes, J2
Gerdes, M1
Beaumont, E1
Cook, L1
Dhanireddy, R1
Kopleman, A1
Jarret, R1
Gong, A1
Anday, E1
Boros, S2
Bucciarelli, R1
Burchfield, D1
Zucker, J1
Sauve, R1
Vincer, M1
Bard, H2
Derleth, D2
Stevenson, D1
Pauly, T1
Robertson, C1
McMillan, D2
Chernick, V1
Finer, N2
Schiff, D2
Watts, J1
Krzeski, R1
Garland, J1
Buck, R1
Weinberg, M1
Sherman, MP1
Campbell, LA1
Merritt, TA1
Long, WA1
Gunkel, JH1
Curstedt, T1
Robertson, B1
Majeed-Saidan, MA1
al-Hifzi, I1
Khan, M1
Rogers, D1
Abbasi, S1
Bhutani, VK1
Gerdes, JS1
Balaraman, V1
Meister, J1
Ku, TL1
Sood, SL1
Tam, E1
Killeen, J1
Uyehara, CF1
Egan, E1
Bhatt-Mehta, V1
Schumacher, RE1
van Houten, J1
McMurray, B1
Peliowski, A1
Walker, D1
Wold, D1
Sankaran, K1
Corbet, A1
Allen, A1
Vaughan, R1
Houle, L1
Edwards, K1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pulse Oximetry With Clinical Observation to Screen for Lung Disease in Neonates[NCT02533583]15,000 participants (Anticipated)Observational2015-11-30Active, not recruiting
Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants: an International Multicentric Randomized Control Trial (LUNG Study)[NCT05198375]668 participants (Anticipated)Interventional2022-04-05Recruiting
Comparison of Two Different Natural Surfactants in the Treatment of Pulmonary Hemorrhage[NCT01860014]20 participants (Actual)Interventional2010-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phosphorylcholine and Lung Diseases

ArticleYear
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012

Trials

10 trials available for phosphorylcholine and Lung Diseases

ArticleYear
One-year follow-up of 66 premature infants weighing 500 to 699 grams treated with a single dose of synthetic surfactant or air placebo at birth: results of a double-blind trial. American Exosurf Neonatal Study Group I.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up St

1995
One-year follow-up of 273 infants with birth weights of 700 to 1100 grams after prophylactic treatment of respiratory distress syndrome with synthetic surfactant or air placebo. American Exosurf Neonatal Study Group I.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Fem

1995
Health and neurodevelopmental outcome at 1-year adjusted age in 508 infants weighing 700 to 1100 grams who received prophylaxis with one versus three doses of synthetic surfactant. American Exosurf Neonatal Study Groups I and II.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies

1995
One-year follow-up evaluation of 260 premature infants with respiratory distress syndrome and birth weights of 700 to 1350 grams randomized to two rescue doses of synthetic surfactant or air placebo. American Exosurf Neonatal Study Group I.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up St

1995
Outcome at 1-year adjusted age of 957 infants weighing more than 1250 grams with respiratory distress syndrome randomized to receive synthetic surfactant or air placebo. American and Canadian Exosurf Neonatal Study Groups.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Fem

1995
Effects of two rescue doses of synthetic surfactant in 344 infants with respiratory distress syndrome weighing 750 to 1249 grams: a double-blind, placebo-controlled multicenter Canadian trial. Canadian Exosurf Neonatal Study Group.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Lung D

1995
Long-term pulmonary consequences of respiratory distress syndrome in preterm infants treated with exogenous surfactant.
    The Journal of pediatrics, 1993, Volume: 122, Issue:3

    Topics: Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Prema

1993
A multicenter, randomized trial comparing synthetic surfactant with modified bovine surfactant extract in the treatment of neonatal respiratory distress syndrome. Vermont-Oxford Neonatal Network.
    Pediatrics, 1996, Volume: 97, Issue:1

    Topics: Biological Products; Chronic Disease; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Low

1996
Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
    The Journal of pediatrics, 1992, Volume: 120, Issue:2 Pt 2

    Topics: Autopsy; Double-Blind Method; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Incidence; Infa

1992
Retrospective search for bleeding diathesis among premature newborn infants with pulmonary hemorrhage after synthetic surfactant treatment. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
    The Journal of pediatrics, 1992, Volume: 120, Issue:2 Pt 2

    Topics: Double-Blind Method; Drug Combinations; Fatty Alcohols; Hemorrhagic Disorders; Humans; Infant, Newbo

1992

Other Studies

10 other studies available for phosphorylcholine and Lung Diseases

ArticleYear
Nebulized synthetic surfactant in reperfusion injury after single lung transplantation.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:2

    Topics: Adult; Aerosols; Drug Combinations; Fatty Alcohols; Female; Humans; Lung Diseases; Lung Transplantat

1995
Artificial surfactant attenuates hyperoxic lung injury in primates. I. Physiology and biochemistry.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:5

    Topics: Animals; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Fatty Alcohols; Hemodynamics; Lung Di

1995
Artificial surfactant attenuates hyperoxic lung injury in primates. II. Morphometric analysis.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:5

    Topics: Aerosols; Animals; Blood Gas Analysis; Cell Division; Drug Combinations; Endothelium; Fatty Alcohols

1995
Lysis of red blood cells and alveolar epithelial toxicity by therapeutic pulmonary surfactants.
    Pediatric research, 1995, Volume: 37, Issue:1

    Topics: Animals; Biological Products; Drug Combinations; Epithelial Cells; Epithelium; Fatty Alcohols; Hemol

1995
Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study.
    Pediatrics, 1994, Volume: 94, Issue:5

    Topics: Cohort Studies; Drug Combinations; Ductus Arteriosus, Patent; Fatty Alcohols; Female; Hemorrhage; Hu

1994
Effect of different surfactants on pulmonary group B streptococcal infection in premature rabbits.
    The Journal of pediatrics, 1994, Volume: 125, Issue:6 Pt 1

    Topics: Animals; Animals, Newborn; Biological Products; Cell Division; Drug Combinations; Fatty Alcohols; Lu

1994
Pulmonary haemorrhage in low-birthweight babies.
    Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837

    Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Hyaline Membrane Disease; Infant, Low Birth W

1993
Pulmonary haemorrhage, surfactant, and low-birthweight babies.
    Lancet (London, England), 1993, Mar-13, Volume: 341, Issue:8846

    Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Lu

1993
Lavage administration of dilute surfactants after acute lung injury in neonatal piglets.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:1

    Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage; Disease Models, Animal; Drug Combinations; Fatty

1998
Criteria for use of colfosceril (Exosurf) in neonates.
    Clinical pharmacy, 1992, Volume: 11, Issue:4

    Topics: Apnea; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Newborn; Intubation, Intratrac

1992