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phosphorylcholine and Libman-Sacks Disease

phosphorylcholine has been researched along with Libman-Sacks Disease in 17 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"Glomerulonephritis was addressed by detection of proteinuria, and immunoglobulin complex deposition in the mesangium of the kidneys of the mice by immunofluorescence."5.42Successful modulation of murine lupus nephritis with tuftsin-phosphorylcholine. ( Barshak, I; Bashi, T; Ben-Ami Shor, D; Blank, M; Fridkin, M; Gendelman, O; Shoenfeld, Y; Versini, M; Volkov, A, 2015)
"IgM antibodies against phosphorylcholine (anti-PC) are negatively associated with atherosclerosis, cardiovascular disease (CVD) and systemic lupus erythematosus (SLE), where the risk of CVD and atherosclerosis is high."3.88IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors. ( Ajeganova, S; Frostegård, J; Gillgren, P; Liu, A; Lundström, SL; Rahman, M; Steuer, J; Sun, J; Zhang, B; Zubarev, RA, 2018)
"Atherosclerosis is the main cause of CVD in the general population, and in SLE, increased atherosclerosis, especially the prevalence of atherosclerotic plaques, has been demonstrated."3.01Systemic lupus erythematosus and cardiovascular disease. ( Frostegård, J, 2023)
"Atherosclerosis is a chronic inflammatory disease characterized by the presence of activated immune-competent cells in the lesions, producing mainly proinflammatory cytokines."2.45Natural antibodies against phosphorylcholine in cardiovascular disease. ( de Faire, U; Frostegård, J, 2009)
"Glomerulonephritis was addressed by detection of proteinuria, and immunoglobulin complex deposition in the mesangium of the kidneys of the mice by immunofluorescence."1.42Successful modulation of murine lupus nephritis with tuftsin-phosphorylcholine. ( Barshak, I; Bashi, T; Ben-Ami Shor, D; Blank, M; Fridkin, M; Gendelman, O; Shoenfeld, Y; Versini, M; Volkov, A, 2015)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's0 (0.00)18.2507
2000's7 (41.18)29.6817
2010's7 (41.18)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Frostegård, J6
Sun, J1
Lundström, SL1
Zhang, B1
Zubarev, RA1
Steuer, J1
Gillgren, P1
Rahman, M2
Ajeganova, S1
Liu, A2
Villamil-Gómez, WE1
Calderón-Gomezcaseres, Á1
Rodriguez-Morales, AJ1
López, P1
Rodríguez-Carrio, J1
Martínez-Zapico, A1
Pérez-Álvarez, ÁI1
Benavente, L1
Caminal-Montero, L1
Suárez, A1
Grönwall, C2
Reynolds, H1
Kim, JK1
Buyon, J1
Goldberg, JD1
Clancy, RM1
Silverman, GJ2
Bashi, T1
Blank, M2
Ben-Ami Shor, D1
Fridkin, M1
Versini, M1
Gendelman, O1
Volkov, A1
Barshak, I1
Shoenfeld, Y2
Sing, S1
Golabkesh, Z1
Fiskesund, R1
Gustafsson, T2
Jogestrand, T2
Frostegård, AG1
Hafström, I1
Su, J2
Hua, X2
Concha, H1
Svenungsson, E1
Cederholm, A1
Zandman-Goddard, G1
de Faire, U2
Anania, C1
Vikström, M1
Heimbürger, M1
Akhter, E1
Oh, C1
Burlingame, RW1
Petri, M1
Das, T1
Sen, AK1
Kempf, T1
Pramanik, SR1
Mandal, C2
Sharma, A1
Isenberg, DA1
Diamond, B1
Carson, MJ1
Lo, D1
Kabarowski, JH1
Zhu, K1
Le, LQ1
Witte, ON1
Xu, Y1
Zouali, M1
Migliorini, P1
Stollar, DB1

Reviews

3 reviews available for phosphorylcholine and Libman-Sacks Disease

ArticleYear
Systemic lupus erythematosus and cardiovascular disease.
    Journal of internal medicine, 2023, Volume: 293, Issue:1

    Topics: Antibodies, Antiphospholipid; Atherosclerosis; Cardiovascular Diseases; Humans; Inflammation; Lupus

2023
Intravenous immunoglobulins in systemic lupus erythematosus: from the bench to the bedside.
    Lupus, 2009, Volume: 18, Issue:10

    Topics: Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Antiphospholipid Syndrome; Humans; Immunoglobu

2009
Natural antibodies against phosphorylcholine in cardiovascular disease.
    Annals of the New York Academy of Sciences, 2009, Volume: 1173

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Immunoglobulin M; Lipoproteins, LDL; Lupu

2009

Other Studies

14 other studies available for phosphorylcholine and Libman-Sacks Disease

ArticleYear
IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors.
    Atherosclerosis, 2018, Volume: 268

    Topics: Atherosclerosis; Autoimmunity; Case-Control Studies; Cells, Cultured; Dendritic Cells; Female; Flow

2018
Visceral leishmaniasis in a patient with systemic lupus erythematosus from Colombia, Latin America.
    Le infezioni in medicina, 2019, Mar-01, Volume: 27, Issue:1

    Topics: Adult; Antiprotozoal Agents; Colombia; Humans; Leishmaniasis, Visceral; Lupus Erythematosus, Systemi

2019
IgM anti-phosphorylcholine antibodies associate with senescent and IL-17+ T cells in SLE patients with a pro-inflammatory lipid profile.
    Rheumatology (Oxford, England), 2020, 02-01, Volume: 59, Issue:2

    Topics: Adult; Atherosclerosis; Autoantibodies; Biomarkers; Carotid Arteries; Female; Humans; Immunoglobulin

2020
Relation of carotid plaque with natural IgM antibodies in patients with systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2014, Volume: 153, Issue:1

    Topics: Adult; Autoantibodies; Biomarkers; Carotid Arteries; Female; Humans; Immunoglobulin M; Lupus Erythem

2014
Successful modulation of murine lupus nephritis with tuftsin-phosphorylcholine.
    Journal of autoimmunity, 2015, Volume: 59

    Topics: Animals; Autoantibodies; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Glomerul

2015
IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms.
    Clinical immunology (Orlando, Fla.), 2016, Volume: 166-167

    Topics: Adult; Apoptosis; Atherosclerosis; B-Lymphocytes; Biomarkers; Carotid Intima-Media Thickness; CD3 Co

2016
Natural antibodies against phosphorylcholine as potential protective factors in SLE.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:8

    Topics: Adult; Autoantibodies; Binding, Competitive; Cardiovascular Diseases; Cross Reactions; Endothelium,

2008
Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus erythematosus.
    Arthritis research & therapy, 2010, Volume: 12, Issue:6

    Topics: Autoantibodies; Autoantigens; Carotid Arteries; Enzyme-Linked Immunosorbent Assay; Female; Humans; I

2010
IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE.
    Clinical immunology (Orlando, Fla.), 2012, Volume: 142, Issue:3

    Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Antigens; Apoptosis; Autoantibodies; Cardiovascular Disease

2012
Induction of glycosylation in human C-reactive protein under different pathological conditions.
    The Biochemical journal, 2003, Jul-15, Volume: 373, Issue:Pt 2

    Topics: Amino Acid Sequence; C-Reactive Protein; Electrophoresis, Polyacrylamide Gel; Galactose; Glucose; Gl

2003
Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: clues to their origin.
    Journal of autoimmunity, 2001, Volume: 16, Issue:4

    Topics: Antibodies, Antinuclear; Cross Reactions; Humans; Immunoglobulin G; Immunoglobulin Isotypes; Lupus E

2001
Immunology. The push-me pull-you of T cell activation.
    Science (New York, N.Y.), 2001, Jul-27, Volume: 293, Issue:5530

    Topics: Animals; Antigen Presentation; Antigens; Arteriosclerosis; B-Lymphocytes; Cell Cycle Proteins; Human

2001
Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.
    Science (New York, N.Y.), 2001, Jul-27, Volume: 293, Issue:5530

    Topics: Animals; Arteriosclerosis; Calcium; Cell Cycle Proteins; Cell Line; Chemotaxis, Leukocyte; Humans; J

2001
Murine lupus anti-DNA antibodies cross-react with the hapten (4-hydroxy-5-iodo-3-nitrophenyl)acetyl, but immunization-induced anti-DNA antibodies do not.
    European journal of immunology, 1987, Volume: 17, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Cross Reactions; DNA; DNA, Si

1987