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phosphorylcholine and Leukocytosis

phosphorylcholine has been researched along with Leukocytosis in 5 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Leukocytosis: A transient increase in the number of leukocytes in a body fluid.

Research Excerpts

ExcerptRelevanceReference
"34 patients with metastatic colorectal cancer were treated with the ether lipid miltefosine (hexadecylphosphocholine)."9.07Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer. ( Planting, AS; Stoter, G; Verweij, J, 1993)
" Perifosine is a novel alkyl-lysophospholipid that can induce apoptosis in multiple myeloma (MM) tumor cells, both in vitro and in vivo."7.74Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model. ( Anderson, KC; Bronson, R; Catley, L; Chauhan, D; Hideshima, T; Munshi, NC; Neri, P; Song, W; Tai, YT; Tassone, P, 2007)
"34 patients with metastatic colorectal cancer were treated with the ether lipid miltefosine (hexadecylphosphocholine)."5.07Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer. ( Planting, AS; Stoter, G; Verweij, J, 1993)
" Perifosine is a novel alkyl-lysophospholipid that can induce apoptosis in multiple myeloma (MM) tumor cells, both in vitro and in vivo."3.74Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model. ( Anderson, KC; Bronson, R; Catley, L; Chauhan, D; Hideshima, T; Munshi, NC; Neri, P; Song, W; Tai, YT; Tassone, P, 2007)
" In addition, at the highest dosage group in rats, an increase in white blood cell counts (WBC) was observed."2.67Increases in leucocyte and platelet counts induced by the alkyl phospholipid hexadecylphosphocholine. ( Drogendijk, TE; Oosterom, R; Planting, AS; Pronk, LC; Stoter, G; Verweij, J, 1994)
" A dose-response relationship was seen after daily oral treatment with complete suppression of tumor growth at doses of 46."1.27Characterization of the antitumor activity of hexadecylphosphocholine (D 18506). ( Berger, MR; Eibl, H; Engel, J; Hilgard, P; Schumacher, W; Stekar, J; Unger, C; Voegeli, R, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Catley, L1
Hideshima, T1
Chauhan, D1
Neri, P1
Tassone, P1
Bronson, R1
Song, W1
Tai, YT1
Munshi, NC1
Anderson, KC1
Pronk, LC1
Planting, AS2
Oosterom, R1
Drogendijk, TE1
Stoter, G2
Verweij, J2
Murray, SE1
Lallman, HR1
Heard, AD1
Rittenberg, MB1
Stenzel-Poore, MP1
Hilgard, P1
Stekar, J1
Voegeli, R1
Engel, J1
Schumacher, W1
Eibl, H1
Unger, C1
Berger, MR1

Trials

2 trials available for phosphorylcholine and Leukocytosis

ArticleYear
Increases in leucocyte and platelet counts induced by the alkyl phospholipid hexadecylphosphocholine.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma,

1994
Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Leuk

1993

Other Studies

3 other studies available for phosphorylcholine and Leukocytosis

ArticleYear
Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model.
    Experimental hematology, 2007, Volume: 35, Issue:7

    Topics: Animals; Apoptosis; Cell Line; Female; Hematopoiesis; Humans; Hyperplasia; Leukocytosis; Mice; Multi

2007
A genetic model of stress displays decreased lymphocytes and impaired antibody responses without altered susceptibility to Streptococcus pneumoniae.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jul-15, Volume: 167, Issue:2

    Topics: Animals; Antibody Formation; B-Lymphocytes; Genetic Predisposition to Disease; Hemocyanins; Injectio

2001
Characterization of the antitumor activity of hexadecylphosphocholine (D 18506).
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Choline; Cyclophosphamide; Dose-Response Re

1988