Page last updated: 2024-10-19

phosphorylcholine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

phosphorylcholine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 5 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research Excerpts

ExcerptRelevanceReference
"Treatment with perifosine (20 μmol/L) resulted in autophagy in CML cells as shown by the increased formation of acidic vesicular organelles and the accumulation of LC3-II."1.38Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro. ( Liu, YY; Qian, WB; Tong, Y; You, LS, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmad, HM1
Muiwo, P1
Muthuswami, R1
Bhattacharya, A1
Tong, Y1
Liu, YY1
You, LS1
Qian, WB1
Konstantinov, SM2
Eibl, H2
Berger, MR2
Topashka-Ancheva, M1
Benner, A1
Vehmeyer, K1
Unger, C1

Other Studies

5 other studies available for phosphorylcholine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
FosB regulates expression of miR-22 during PMA induced differentiation of K562 cells to megakaryocytes.
    Biochimie, 2017, Volume: 133

    Topics: Cell Differentiation; Early Growth Response Protein 1; Early Growth Response Protein 2; Gene Express

2017
Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cell Line, Tumor; Cell Sur

2012
Alkylphosphocholines induce apoptosis in HL-60 and U-937 leukemic cells.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:3

    Topics: Apoptosis; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Leukemia, Myel

1998
Alkylphosphocholines: Effects on human leukemic cell lines and normal bone marrow cells.
    International journal of cancer, 1998, Aug-31, Volume: 77, Issue:5

    Topics: Alkylation; Animals; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cell Cycle; Cell Division;

1998
Hexadecylphosphocholine stimulates the colony-stimulating factor-dependent growth of hemopoietic progenitor cells.
    Experimental hematology, 1992, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Colony-Stimulating Factors; Dose-Response R

1992