phosphorylcholine has been researched along with Hyperplasia in 9 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial was a randomized controlled study of zotarolimus-eluting, phosphorylcholine-coated, cobalt-alloy stents for the treatment of de novo coronary lesions compared with using PES for the same treatment." | 9.14 | Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. ( Ako, J; Fitzgerald, PJ; Hasegawa, T; Honda, Y; Kandzari, DE; Leon, MB; Miyazawa, A; Sakurai, R; Tsujino, I; Waseda, K; Yock, PG, 2009) |
| " Perifosine is a novel alkyl-lysophospholipid that can induce apoptosis in multiple myeloma (MM) tumor cells, both in vitro and in vivo." | 7.74 | Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model. ( Anderson, KC; Bronson, R; Catley, L; Chauhan, D; Hideshima, T; Munshi, NC; Neri, P; Song, W; Tai, YT; Tassone, P, 2007) |
| " The purpose of this study was to determine the efficacy of local methylprednisolone (MP) delivery using PC-coated stents to inhibit inflammatory response and in-stent neointimal hyperplasia in an overstretched porcine coronary model." | 7.72 | Local methylprednisolone delivery using a BiodivYsio phosphorylcholine-coated drug-delivery stent reduces inflammation and neointimal hyperplasia in a porcine coronary stent model. ( De Scheerder, I; Huang, Y; Li, S; Liu, X; Verbeken, E; Wang, L, 2003) |
| "In an attempt to reduce platelet deposition and inhibit neointimal hyperplasia, we evaluated the effect of coating expanded polytetrafluoroethylene (ePTFE) grafts with phosphorylcholine (PC), a lipid found in animal cell membranes, in a dog model of femoral arteriovenous (AV) grafts." | 7.70 | Phosphorylcholine coating of ePTFE reduces platelet deposition and neointimal hyperplasia in arteriovenous grafts. ( Chen, C; Hanson, SR; Lumsden, AB; Ofenloch, JC; Yianni, YP, 1998) |
| "This study attempts to prevent neointimal hyperplasia by coating the graft luminal surface with a derivative of phosphorylcholine (PC), thereby providing a biocompatible surface with the assumption of limiting pannus tissue ingrowth from the graft anastomoses." | 7.69 | Phosphorylcholine coating of ePTFE grafts reduces neointimal hyperplasia in canine model. ( Campbell, EJ; Chen, C; Hanson, SR; Lumsden, AB; Noe, B; Ofenloch, JC; Stratford, PW; Taylor, AS; Yianni, YP, 1997) |
| "The ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial was a randomized controlled study of zotarolimus-eluting, phosphorylcholine-coated, cobalt-alloy stents for the treatment of de novo coronary lesions compared with using PES for the same treatment." | 5.14 | Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. ( Ako, J; Fitzgerald, PJ; Hasegawa, T; Honda, Y; Kandzari, DE; Leon, MB; Miyazawa, A; Sakurai, R; Tsujino, I; Waseda, K; Yock, PG, 2009) |
| " Perifosine is a novel alkyl-lysophospholipid that can induce apoptosis in multiple myeloma (MM) tumor cells, both in vitro and in vivo." | 3.74 | Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model. ( Anderson, KC; Bronson, R; Catley, L; Chauhan, D; Hideshima, T; Munshi, NC; Neri, P; Song, W; Tai, YT; Tassone, P, 2007) |
| " The purpose of this study was to determine the efficacy of local methylprednisolone (MP) delivery using PC-coated stents to inhibit inflammatory response and in-stent neointimal hyperplasia in an overstretched porcine coronary model." | 3.72 | Local methylprednisolone delivery using a BiodivYsio phosphorylcholine-coated drug-delivery stent reduces inflammation and neointimal hyperplasia in a porcine coronary stent model. ( De Scheerder, I; Huang, Y; Li, S; Liu, X; Verbeken, E; Wang, L, 2003) |
| "In an attempt to reduce platelet deposition and inhibit neointimal hyperplasia, we evaluated the effect of coating expanded polytetrafluoroethylene (ePTFE) grafts with phosphorylcholine (PC), a lipid found in animal cell membranes, in a dog model of femoral arteriovenous (AV) grafts." | 3.70 | Phosphorylcholine coating of ePTFE reduces platelet deposition and neointimal hyperplasia in arteriovenous grafts. ( Chen, C; Hanson, SR; Lumsden, AB; Ofenloch, JC; Yianni, YP, 1998) |
| "This study attempts to prevent neointimal hyperplasia by coating the graft luminal surface with a derivative of phosphorylcholine (PC), thereby providing a biocompatible surface with the assumption of limiting pannus tissue ingrowth from the graft anastomoses." | 3.69 | Phosphorylcholine coating of ePTFE grafts reduces neointimal hyperplasia in canine model. ( Campbell, EJ; Chen, C; Hanson, SR; Lumsden, AB; Noe, B; Ofenloch, JC; Stratford, PW; Taylor, AS; Yianni, YP, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caroff, J | 1 |
| Tamura, T | 1 |
| King, RM | 1 |
| Lylyk, PN | 1 |
| Langan, ET | 1 |
| Brooks, OW | 1 |
| Clarençon, F | 1 |
| Wainwright, JM | 1 |
| Spelle, L | 1 |
| Marosfoi, M | 1 |
| Gounis, MJ | 1 |
| Puri, AS | 1 |
| Trousil, S | 1 |
| Lee, P | 1 |
| Pinato, DJ | 1 |
| Ellis, JK | 1 |
| Dina, R | 1 |
| Aboagye, EO | 1 |
| Keun, HC | 1 |
| Sharma, R | 1 |
| van Beusekom, HM | 1 |
| Ferrero, V | 1 |
| Ribichini, F | 1 |
| van der Giessen, WJ | 1 |
| Waseda, K | 1 |
| Miyazawa, A | 1 |
| Ako, J | 1 |
| Hasegawa, T | 1 |
| Tsujino, I | 1 |
| Sakurai, R | 1 |
| Yock, PG | 1 |
| Honda, Y | 1 |
| Kandzari, DE | 1 |
| Leon, MB | 1 |
| Fitzgerald, PJ | 1 |
| Huang, Y | 1 |
| Liu, X | 1 |
| Wang, L | 1 |
| Verbeken, E | 1 |
| Li, S | 1 |
| De Scheerder, I | 1 |
| Dubé, H | 1 |
| Clifford, AG | 1 |
| Barry, CM | 1 |
| Schwarten, DE | 1 |
| Schwartz, LB | 1 |
| Catley, L | 1 |
| Hideshima, T | 1 |
| Chauhan, D | 1 |
| Neri, P | 1 |
| Tassone, P | 1 |
| Bronson, R | 1 |
| Song, W | 1 |
| Tai, YT | 1 |
| Munshi, NC | 1 |
| Anderson, KC | 1 |
| Chen, C | 2 |
| Lumsden, AB | 2 |
| Ofenloch, JC | 2 |
| Noe, B | 1 |
| Campbell, EJ | 1 |
| Stratford, PW | 1 |
| Yianni, YP | 2 |
| Taylor, AS | 1 |
| Hanson, SR | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled Trial of the Medtronic Endeavor Drug (ABT-578) Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions[NCT00217269] | 1,548 participants (Actual) | Interventional | 2005-04-30 | Completed | |||
| [NCT00973375] | 30 participants (Anticipated) | Observational | 2009-05-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for phosphorylcholine and Hyperplasia
| Article | Year |
|---|---|
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible | 2009 |
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible | 2009 |
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible | 2009 |
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible | 2009 |
8 other studies available for phosphorylcholine and Hyperplasia
| Article | Year |
|---|---|
Phosphorylcholine surface modified flow diverter associated with reduced intimal hyperplasia.
Topics: Animals; Coronary Vessels; Endovascular Procedures; Hyperplasia; Intracranial Aneurysm; Neointima; P | 2018 |
Alterations of choline phospholipid metabolism in endometrial cancer are caused by choline kinase alpha overexpression and a hyperactivated deacylation pathway.
Topics: Adenocarcinoma; Cell Line; Cell Line, Tumor; Choline; Choline Kinase; Endometrial Neoplasms; Female; | 2014 |
Quinaprilat-eluting stents do not attenuate intimal thickening following stenting in porcine coronary arteries.
Topics: Angiography; Angioplasty, Balloon; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessel P | 2009 |
Local methylprednisolone delivery using a BiodivYsio phosphorylcholine-coated drug-delivery stent reduces inflammation and neointimal hyperplasia in a porcine coronary stent model.
Topics: Animals; Anti-Inflammatory Agents; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompat | 2003 |
Comparison of the vascular responses to balloon-expandable stenting in the coronary and peripheral circulations: long-term results in an animal model using the TriMaxx stent.
Topics: Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Animals; Arterial Occlusive Diseases; Coated M | 2007 |
Alkyl phospholipid perifosine induces myeloid hyperplasia in a murine myeloma model.
Topics: Animals; Apoptosis; Cell Line; Female; Hematopoiesis; Humans; Hyperplasia; Leukocytosis; Mice; Multi | 2007 |
Phosphorylcholine coating of ePTFE grafts reduces neointimal hyperplasia in canine model.
Topics: Animals; Biocompatible Materials; Blood Vessel Prosthesis; Carotid Arteries; Cell Division; Dogs; Gr | 1997 |
Phosphorylcholine coating of ePTFE reduces platelet deposition and neointimal hyperplasia in arteriovenous grafts.
Topics: Anastomosis, Surgical; Animals; Antimetabolites; Blood Platelets; Bromodeoxyuridine; Cell Division; | 1998 |