Page last updated: 2024-10-19

phosphorylcholine and Filariasis

phosphorylcholine has been researched along with Filariasis in 13 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Filariasis: Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.

Research Excerpts

ExcerptRelevanceReference
"Antiphosphorylcholine antibodies were present in jird sera for the first 12 weeks after larval injection, but thereafter, antibody titers decreased to undetectable levels."1.27Brugia malayi: detection of parasite antigen in sera from infected jirds. ( Weil, GJ, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goodridge, HS2
Deehan, MR1
Harnett, W4
Harnett, MM2
Stepek, G1
Houston, KM1
Egan, CA1
GarcĂ­a, P1
Bancroft, A1
Devaney, E1
Al-Qaoud, KM1
Fleischer, B1
Hoerauf, A1
Lal, RB3
Kumaraswami, V1
Steel, C1
Nutman, TB1
Wenger, JD1
Forsyth, KP1
Kazura, JW1
Ottesen, EA2
Worms, MJ1
Kapil, A1
Grainger, M1
Parkhouse, RM2
Weil, GJ1
Maizels, RM1
Morgan, TM1
Gregory, WF1
Selkirk, ME1
Partono, F1
Almond, NM1

Reviews

2 reviews available for phosphorylcholine and Filariasis

ArticleYear
Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product.
    Cellular signalling, 2005, Volume: 17, Issue:1

    Topics: Animals; B-Lymphocytes; Filariasis; Filarioidea; Humans; Lymphocytes; Macrophages; Phosphorylcholine

2005
Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62.
    Immunology, 2005, Volume: 115, Issue:3

    Topics: Animals; Antibody Formation; B-Lymphocytes; Filariasis; Filarioidea; Glycoproteins; Helminth Protein

2005

Other Studies

11 other studies available for phosphorylcholine and Filariasis

ArticleYear
Investigation of strategies with potential for producing a phosphorylcholine-free version of the filarial nematode immunomodulator, ES-62.
    Journal of helminthology, 2006, Volume: 80, Issue:3

    Topics: Animals; beta-N-Acetylhexosaminidases; Enzyme Inhibitors; Esterases; Filariasis; Filarioidea; Helmin

2006
The analysis of the humoral response of the BALB/c mouse immunized with radiation attenuated third stage larvae of Brugia pahangi.
    Parasite immunology, 1993, Volume: 15, Issue:3

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Brugia pahangi; Electrophoresi

1993
The Xid defect imparts susceptibility to experimental murine filariosis--association with a lack of antibody and IL-10 production by B cells in response to phosphorylcholine.
    International immunology, 1998, Volume: 10, Issue:1

    Topics: Animals; Antibodies, Helminth; B-Lymphocytes; Disease Models, Animal; Disease Susceptibility; Filari

1998
Phosphocholine-containing antigens of Brugia malayi nonspecifically suppress lymphocyte function.
    The American journal of tropical medicine and hygiene, 1990, Volume: 42, Issue:1

    Topics: Adult; Animals; Antigens, Helminth; Brugia; Choline; Dose-Response Relationship, Immunologic; Elepha

1990
Identification of phosphorylcholine epitope-containing antigens in Brugia malayi and relation of serum epitope levels to infection status of jirds with brugian filariasis.
    The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, Helminth; Brugia; Choline; Electrophoresis, Polyacrylamid

1988
Enhanced diagnostic specificity in human filariasis by IgG4 antibody assessment.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:5

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Cross Reactions; Enzyme-Linked Immunosorbent Assa

1988
Origin, kinetics of circulation and fate in vivo of the major excretory-secretory product of Acanthocheilonema viteae.
    Parasitology, 1989, Volume: 99 Pt 2

    Topics: Animals; Antigens, Helminth; Cross Reactions; Dipetalonema; Dipetalonema Infections; Electrophoresis

1989
Antibodies to phosphocholine-bearing antigens in lymphatic filariasis and changes following treatment with diethylcarbamazine.
    Clinical and experimental immunology, 1989, Volume: 75, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antibodies; Antigens; Blood; Choline; Diethylcarbamazine; Elephant

1989
Brugia malayi: detection of parasite antigen in sera from infected jirds.
    Experimental parasitology, 1988, Volume: 67, Issue:1

    Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Brugia; Elephantiasis, Fi

1988
Circulating antibodies and antigens in Presbytis monkeys infected with the filarial parasite Wuchereria bancrofti.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1988, Volume: 39, Issue:3

    Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Antigens, Surface; Blotti

1988
The Ig class distribution of anti-phosphoryl choline responses in mice infected with parasitic nematodes.
    Immunology, 1986, Volume: 59, Issue:4

    Topics: Animals; Choline; Dipetalonema Infections; Filariasis; Immunoglobulins; Mice; Mice, Inbred Strains;

1986