phosphorylcholine has been researched along with Dermatitis, Atopic in 9 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We demonstrate that miltefosine is locally active in patients with AD and led to a sustained clinical improvement in local skin inflammation." | 5.14 | Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis. ( Dölle, S; Hoser, D; Loddenkemper, C; Maurer, M; Rasche, C; Worm, M; Zuberbier, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brauweiler, AM | 1 |
| Goleva, E | 1 |
| Leung, DYM | 1 |
| Imokawa, G | 3 |
| Andoh, T | 2 |
| Saito, A | 2 |
| Kuraishi, Y | 2 |
| Dölle, S | 1 |
| Hoser, D | 1 |
| Rasche, C | 1 |
| Loddenkemper, C | 1 |
| Maurer, M | 2 |
| Zuberbier, T | 1 |
| Worm, M | 1 |
| Haza, S | 1 |
| Magerl, M | 1 |
| Metz, M | 1 |
| Weller, K | 1 |
| Siebenhaar, F | 1 |
| Okamoto, R | 1 |
| Arikawa, J | 1 |
| Ishibashi, M | 1 |
| Kawashima, M | 2 |
| Takagi, Y | 1 |
| Di Marzio, L | 1 |
| Centi, C | 1 |
| Cinque, B | 1 |
| Masci, S | 1 |
| Giuliani, M | 1 |
| Arcieri, A | 1 |
| Zicari, L | 1 |
| De Simone, C | 1 |
| Cifone, MG | 1 |
| Murata, Y | 1 |
| Ogata, J | 1 |
| Higaki, Y | 1 |
| Yada, Y | 1 |
| Higuchi, K | 1 |
| Tsuchiya, T | 1 |
| Kawainami, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Pathology Assessment With Optical Technologies (SPOT): a Cross- Sectional Clinical Study in Atopic Dermatitis Patients and Healthy Subjects[NCT04295824] | 80 participants (Anticipated) | Observational | 2020-08-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for phosphorylcholine and Dermatitis, Atopic
| Article | Year |
|---|---|
A possible mechanism underlying the ceramide deficiency in atopic dermatitis: expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide.
Topics: Amidohydrolases; Ceramides; Dermatitis, Atopic; Epidermis; Glucosylceramides; Humans; Phosphorylchol | 2009 |
Miltefosine: a novel treatment option for mast cell-mediated diseases.
Topics: Antineoplastic Agents; Dermatitis, Atopic; Humans; Mast Cells; Mastocytosis; Phosphorylcholine; Urti | 2013 |
2 trials available for phosphorylcholine and Dermatitis, Atopic
| Article | Year |
|---|---|
Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Derma | 2010 |
Effect of the lactic acid bacterium Streptococcus thermophilus on stratum corneum ceramide levels and signs and symptoms of atopic dermatitis patients.
Topics: Administration, Topical; Adolescent; Adult; Ceramides; Dermatitis, Atopic; Female; Humans; Male; Pho | 2003 |
5 other studies available for phosphorylcholine and Dermatitis, Atopic
| Article | Year |
|---|---|
Th2 cytokines increase Staphylococcus aureus alpha toxin-induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6).
Topics: Bacterial Toxins; Cell Death; Cells, Cultured; Ceramides; Cytokines; Dermatitis, Atopic; Hemolysin P | 2014 |
Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin.
Topics: Animals; Calcium; Dermatitis, Atopic; Ganglia, Spinal; Histamine; Histamine H1 Antagonists, Non-Seda | 2009 |
Involvement of leukotriene B4 in spontaneous itch-related behaviour in NC mice with atopic dermatitis-like skin lesions.
Topics: Administration, Topical; Animals; Arachidonate 5-Lipoxygenase; Dermatitis, Atopic; Disease Models, A | 2011 |
Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis.
Topics: Adolescent; Adult; Ceramides; Dermatitis, Atopic; Epidermis; Humans; Phosphorylcholine; Psychosine; | 2003 |
Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency?
Topics: Amidohydrolases; Ceramides; Dermatitis, Atopic; Humans; Hydrolysis; Phosphorylcholine; Sphingomyelin | 1996 |