Page last updated: 2024-10-19

phosphorylcholine and Cystic Fibrosis

phosphorylcholine has been researched along with Cystic Fibrosis in 3 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Miltefosine has structural similarity to the PC and sphingomyelin substrates of PlcHR, and we found that it inhibits the cleavage of these choline-containing lipids in vitro."1.37Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection. ( Allard, JL; Allen, GB; Gross, MJ; Hogan, DA; Leclair, LW; Lundblad, LK; Rajamani, S; Vasil, ML; Wargo, MJ, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wargo, MJ1
Gross, MJ1
Rajamani, S1
Allard, JL1
Lundblad, LK1
Allen, GB1
Vasil, ML1
Leclair, LW1
Hogan, DA1
Rubin, BK1
Krieg, DP1
Bass, JA1
Mattingly, SJ1

Reviews

1 review available for phosphorylcholine and Cystic Fibrosis

ArticleYear
Therapeutic aerosols and airway secretions.
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 1996,Spring, Volume: 9, Issue:1

    Topics: Aerosols; Animals; Anti-Asthmatic Agents; Asthma; Cystic Fibrosis; Drug Combinations; Fatty Alcohols

1996

Other Studies

2 other studies available for phosphorylcholine and Cystic Fibrosis

ArticleYear
Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection.
    American journal of respiratory and critical care medicine, 2011, Aug-01, Volume: 184, Issue:3

    Topics: Animals; Antifungal Agents; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Disease Models, Animal; H

2011
Phosphorylcholine stimulates capsule formation of phosphate-limited mucoid Pseudomonas aeruginosa.
    Infection and immunity, 1988, Volume: 56, Issue:4

    Topics: Alginates; Choline; Cystic Fibrosis; Extracellular Space; Glucuronic Acid; Hexuronic Acids; Microsco

1988