phosphorylcholine has been researched along with Cystic Fibrosis in 3 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Excerpt | Relevance | Reference |
---|---|---|
"Miltefosine has structural similarity to the PC and sphingomyelin substrates of PlcHR, and we found that it inhibits the cleavage of these choline-containing lipids in vitro." | 1.37 | Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection. ( Allard, JL; Allen, GB; Gross, MJ; Hogan, DA; Leclair, LW; Lundblad, LK; Rajamani, S; Vasil, ML; Wargo, MJ, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wargo, MJ | 1 |
Gross, MJ | 1 |
Rajamani, S | 1 |
Allard, JL | 1 |
Lundblad, LK | 1 |
Allen, GB | 1 |
Vasil, ML | 1 |
Leclair, LW | 1 |
Hogan, DA | 1 |
Rubin, BK | 1 |
Krieg, DP | 1 |
Bass, JA | 1 |
Mattingly, SJ | 1 |
1 review available for phosphorylcholine and Cystic Fibrosis
Article | Year |
---|---|
Therapeutic aerosols and airway secretions.
Topics: Aerosols; Animals; Anti-Asthmatic Agents; Asthma; Cystic Fibrosis; Drug Combinations; Fatty Alcohols | 1996 |
2 other studies available for phosphorylcholine and Cystic Fibrosis
Article | Year |
---|---|
Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection.
Topics: Animals; Antifungal Agents; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Disease Models, Animal; H | 2011 |
Phosphorylcholine stimulates capsule formation of phosphate-limited mucoid Pseudomonas aeruginosa.
Topics: Alginates; Choline; Cystic Fibrosis; Extracellular Space; Glucuronic Acid; Hexuronic Acids; Microsco | 1988 |