Page last updated: 2024-10-19

phosphorylcholine and Coronary Restenosis

phosphorylcholine has been researched along with Coronary Restenosis in 23 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Research Excerpts

ExcerptRelevanceReference
"The ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial was a randomized controlled study of zotarolimus-eluting, phosphorylcholine-coated, cobalt-alloy stents for the treatment of de novo coronary lesions compared with using PES for the same treatment."9.14Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. ( Ako, J; Fitzgerald, PJ; Hasegawa, T; Honda, Y; Kandzari, DE; Leon, MB; Miyazawa, A; Sakurai, R; Tsujino, I; Waseda, K; Yock, PG, 2009)
"The ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial was a randomized controlled study of zotarolimus-eluting, phosphorylcholine-coated, cobalt-alloy stents for the treatment of de novo coronary lesions compared with using PES for the same treatment."5.14Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. ( Ako, J; Fitzgerald, PJ; Hasegawa, T; Honda, Y; Kandzari, DE; Leon, MB; Miyazawa, A; Sakurai, R; Tsujino, I; Waseda, K; Yock, PG, 2009)
"Patients (n =1,197) treated for single coronary artery stenosis were enrolled in a prospective, randomized, double-blind study and randomly assigned to receive the Endeavor zotarolimus-eluting phosphorylcholine polymer-coated stent (n= 598) or the same bare metal stent but without the drug or the polymer coating (n=599)."5.12Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial. ( Bonan, R; Fajadet, J; Fitzgerald, PJ; Kuck, KH; Kuntz, RE; Laarman, GJ; Münzel, T; Ormiston, J; Popma, JJ; Wijns, W, 2007)
"Zotarolimus is a recently developed pharmacologic agent with both antiproliferative and anti-inflammatory properties."2.43Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent. ( Kandzari, DE; Leon, MB, 2006)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's20 (86.96)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Waseda, K1
Miyazawa, A1
Ako, J1
Hasegawa, T1
Tsujino, I1
Sakurai, R2
Yock, PG2
Honda, Y2
Kandzari, DE2
Leon, MB5
Fitzgerald, PJ4
Habara, S1
Mitsudo, K2
Kadota, K2
Goto, T1
Fujii, S1
Yamamoto, H1
Katoh, H1
Oka, N1
Fuku, Y1
Hosogi, S1
Hirono, A1
Maruo, T1
Tanaka, H1
Shigemoto, Y1
Hasegawa, D1
Tasaka, H1
Kusunose, M1
Otsuru, S1
Okamoto, Y1
Saito, N1
Tsujimoto, Y1
Sethi, A1
Bahekar, A1
Bhuriya, R1
Bajaj, A1
Singh, PP1
Arora, R1
Khosla, S1
New, G2
Moses, JW3
Roubin, GS2
Colombo, A2
Iyer, SS1
Tio, FO1
Mehran, R2
Kipshidze, N2
Babapulle, MN1
Eisenberg, MJ1
Kipshidze, NN1
Iversen, P1
Kim, HS1
Yiazdi, H1
Dangas, G1
Seaborn, R1
Tio, F1
Waksman, R1
Tsapenko, M1
Stone, GW1
Iyer, S1
Iversen, PL1
Hausleiter, J1
Kastrati, A1
Mehilli, J1
Schühlen, H1
Pache, J1
Dotzer, F1
Glatthor, C1
Siebert, S1
Dirschinger, J1
Schömig, A1
Shinozaki, N1
Yokoi, H1
Iwabuchi, M1
Nosaka, H1
Nobuyoshi, M1
Lowe, R1
Menown, IB1
Nogareda, G1
Penn, IM1
Bakhai, A1
Booth, J1
Delahunty, N1
Nugara, F1
Clayton, T1
McNeill, J1
Davies, SW1
Cumberland, DC2
Stables, RH1
Rodriguez, A1
Rodríguez Alemparte, M1
Fernández Pereira, C1
Sampaolesi, A1
da Rocha Loures Bueno, R1
Vigo, F1
Obregón, A1
Palacios, IF1
Airoldi, F1
Di Mario, C1
Ribichini, F1
Presbitero, P1
Sganzerla, P1
Ferrero, V1
Vassanelli, C1
Briguori, C1
Carlino, M1
Montorfano, M1
Biondi-Zoccai, GG1
Chieffo, A1
Ferrari, A1
Fajadet, J2
Wijns, W2
Laarman, GJ1
Kuck, KH1
Ormiston, J1
Münzel, T1
Popma, JJ3
Bonan, R1
Kuntz, RE2
Abizaid, A3
Lansky, AJ1
Tanajura, LF2
Feres, F2
Staico, R1
Mattos, L1
Chaves, A1
Centemero, M1
Sousa, AG1
Sousa, JE1
Zaugg, MJ1
Schwartz, LB2
Han, Y1
Liang, M1
Kang, J1
Qi, Y1
Deng, J1
Xu, K1
Yan, C1
Fan, D1
Jia, Z1
Yan, X1
Liu, X1
Dong, W1
Sun, F1
Ji, J1
Xu, J1
Ren, K1
Chen, W1
Shen, J1
Qiu, H1
Gao, R1
Hongo, Y1
Yamasaki, M1
Bonneau, HN1
Cutlip, D1
Zimetbaum, P1
Hattori, K1
Solberg, B1
Larracas, C1
Costa, Jde R1
Zheng, H1
Barragan, P1
Corcos, T1
Siméoni, JB1
Favereau, X1
Roquebert, PO1
Guérin, Y1
Sainsous, J1
Grenadier, E1
Roguin, A1
Hertz, I1
Peled, B1
Boulos, M1
Nikolsky, E1
Amikam, S1
Kerner, A1
Cohen, S1
Beyar, R1
Armstrong, J1
Gunn, J1
Arnold, N1
Malik, N1
Chan, KH1
Vick, T1
Stratford, P1
Holt, CM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Controlled Trial of the Medtronic Endeavor Drug (ABT-578) Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions[NCT00217269]1,548 participants (Actual)Interventional2005-04-30Completed
[NCT00973375]30 participants (Anticipated)Observational2009-05-31Recruiting
Non-randomized, Open-label, Historical Control, Single Group Assignment Trial of a Reduced Dose of Unfractionated Heparin in Patients Undergoing Percutaneous Coronary Interventions[NCT00735280]Phase 42,505 participants (Actual)Interventional2008-08-31Completed
A Prospective, Multi-Center, Non-Randomized, Single-Arm Trial to Evaluate the Safety and Feasibility of the TriMaxx Coronary Stent in de Novo Coronary Artery Lesions.[NCT00596661]Phase 1100 participants (Actual)Interventional2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for phosphorylcholine and Coronary Restenosis

ArticleYear
Zotarolimus-eluting stent versus sirolimus-eluting and paclitaxel-eluting stents for percutaneous coronary intervention: a meta-analysis of randomized trials.
    Archives of cardiovascular diseases, 2012, Volume: 105, Issue:11

    Topics: Coated Materials, Biocompatible; Confidence Intervals; Coronary Angiography; Coronary Restenosis; Dr

2012
Coated stents for the prevention of restenosis: Part II.
    Circulation, 2002, Nov-26, Volume: 106, Issue:22

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Antineoplastic Agents; Clinical Trials as Topic; Coa

2002
Local application of antisense for prevention of restenosis.
    Methods in molecular medicine, 2005, Volume: 106

    Topics: Angioplasty; Animals; Catheterization; Clinical Trials as Topic; Coronary Restenosis; Coronary Vesse

2005
Coronary stents: in these days of climate change should all stents wear coats?
    Heart (British Cardiac Society), 2005, Volume: 91 Suppl 3

    Topics: Carbon; Carbon Compounds, Inorganic; Chromium Alloys; Coronary Restenosis; Heparin; Humans; Metals;

2005
Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent.
    Journal of interventional cardiology, 2006, Volume: 19, Issue:5

    Topics: Anti-Inflammatory Agents; Blood Vessel Prosthesis Implantation; Clinical Trials as Topic; Coated Mat

2006

Trials

10 trials available for phosphorylcholine and Coronary Restenosis

ArticleYear
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:8

    Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible

2009
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:8

    Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible

2009
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:8

    Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible

2009
Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:8

    Topics: Aged; Alloys; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Coated Materials, Biocompatible

2009
A randomized trial comparing phosphorylcholine-coated stenting with balloon angioplasty as well as abciximab with placebo for restenosis reduction in small coronary arteries.
    Journal of internal medicine, 2004, Volume: 256, Issue:5

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Coronary Re

2004
Initial and follow-up results of the BiodivYsio phosphorylcholine coated stent for treatment of coronary artery disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:3

    Topics: Aged; Coated Materials, Biocompatible; Coronary Angiography; Coronary Artery Disease; Coronary Reste

2005
The SV stent study: a prospective, multicentre, angiographic evaluation of the BiodivYsio phosphorylcholine coated small vessel stent in small coronary vessels.
    International journal of cardiology, 2005, Jun-22, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Coated Materials, Biocompatible; Cor

2005
Latin American randomized trial of balloon angioplasty vs coronary stenting for small vessels (LASMAL): immediate and long-term results.
    The American journal of medicine, 2005, Volume: 118, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis Implantation; Cineangiography; Coated

2005
17-beta-estradiol eluting stent versus phosphorylcholine-coated stent for the treatment of native coronary artery disease.
    The American journal of cardiology, 2005, Sep-01, Volume: 96, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Coated Materials, Biocompatible; Coronary Angiography; Coronary Dise

2005
Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial.
    Minerva cardioangiologica, 2007, Volume: 55, Issue:1

    Topics: Aged; Australia; Cardiovascular Agents; Coronary Angiography; Coronary Restenosis; Coronary Stenosis

2007
Percutaneous coronary revascularization using a trilayer metal phosphorylcholine-coated zotarolimus-eluting stent.
    The American journal of cardiology, 2007, May-15, Volume: 99, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis Implantation; Cardiovascular Agents; C

2007
Detailed intravascular ultrasound analysis of Zotarolimus-eluting phosphorylcholine-coated cobalt-chromium alloy stent in de novo coronary lesions (results from the ENDEAVOR II trial).
    The American journal of cardiology, 2007, Sep-01, Volume: 100, Issue:5

    Topics: Chromium Alloys; Coated Materials, Biocompatible; Cohort Studies; Coronary Artery Disease; Coronary

2007
Stenting very small coronary narrowings (< 2 mm) using the biocompatible phosphorylcholine-coated coronary stent.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2002, Volume: 55, Issue:3

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Coated Materials, Biocompatible; Coronary Artery Diseas

2002

Other Studies

8 other studies available for phosphorylcholine and Coronary Restenosis

ArticleYear
Serial clinical and angiographic follow-up after phosphorylcholine-coated stent implantation.
    International heart journal, 2011, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Coronary Angiography; Coronary Restenosis; Drug-Eluting Stents; Female; Hum

2011
Estrogen-eluting, phosphorylcholine-coated stent implantation is associated with reduced neointimal formation but no delay in vascular repair in a porcine coronary model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2002, Volume: 57, Issue:2

    Topics: Animals; Coated Materials, Biocompatible; Coronary Restenosis; Drug Delivery Systems; Endothelium, V

2002
Advanced c-myc antisense (AVI-4126)-eluting phosphorylcholine-coated stent implantation is associated with complete vascular healing and reduced neointimal formation in the porcine coronary restenosis model.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2004, Volume: 61, Issue:4

    Topics: Animals; Blood Vessel Prosthesis Implantation; Coated Materials, Biocompatible; Coronary Angiography

2004
Estrogen-eluting stent implantation inhibits neointimal formation and extracellular signal-regulated kinase activation.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Nov-01, Volume: 70, Issue:5

    Topics: Analysis of Variance; Animals; Blotting, Western; Coated Materials, Biocompatible; Coronary Restenos

2007
[Pilot study of a cell membrane like biomimetic drug-eluting coronary stent].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2007, Volume: 24, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Animals; Coated Materials, Biocompatible; Coronary Restenosis; Drug-

2007
Clinical and angiographic results of percutaneous coronary revascularization using a trilayer stainless steel-tantalum-stainless steel phosphorylcholine-coated stent: the TriMaxx trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Dec-01, Volume: 70, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Brazil; Cardiovascular Agents; Cardiovascular Diseases; Corona

2007
Clinical experience with a new biocompatible phosphorylcholine-coated coronary stent.
    The Journal of invasive cardiology, 1999, Volume: 11, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis; Blood Vesse

1999
Angiopeptin-eluting stents: observations in human vessels and pig coronary arteries.
    The Journal of invasive cardiology, 2002, Volume: 14, Issue:5

    Topics: Animals; Cardiovascular Agents; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vesse

2002