Page last updated: 2024-10-19

phosphorylcholine and Coronary Artery Stenosis

phosphorylcholine has been researched along with Coronary Artery Stenosis in 8 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased incidence of adverse events in coronary artery disease (CAD)."7.81Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease. ( Akhavanpoor, M; Buss, SJ; Conradson, G; Doesch, AO; Domschke, G; Erbel, C; Gitsioudis, G; Gleissner, CA; Haeussler, J; Hofmann, NP; Katus, HA; Korosoglou, G; Linden, F, 2015)
"Patients (n =1,197) treated for single coronary artery stenosis were enrolled in a prospective, randomized, double-blind study and randomly assigned to receive the Endeavor zotarolimus-eluting phosphorylcholine polymer-coated stent (n= 598) or the same bare metal stent but without the drug or the polymer coating (n=599)."5.12Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial. ( Bonan, R; Fajadet, J; Fitzgerald, PJ; Kuck, KH; Kuntz, RE; Laarman, GJ; Münzel, T; Ormiston, J; Popma, JJ; Wijns, W, 2007)
"Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased incidence of adverse events in coronary artery disease (CAD)."3.81Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease. ( Akhavanpoor, M; Buss, SJ; Conradson, G; Doesch, AO; Domschke, G; Erbel, C; Gitsioudis, G; Gleissner, CA; Haeussler, J; Hofmann, NP; Katus, HA; Korosoglou, G; Linden, F, 2015)
"Zotarolimus is a recently developed pharmacologic agent with both antiproliferative and anti-inflammatory properties."2.43Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent. ( Kandzari, DE; Leon, MB, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gleissner, CA1
Erbel, C1
Haeussler, J1
Akhavanpoor, M1
Domschke, G1
Linden, F1
Doesch, AO1
Conradson, G1
Buss, SJ1
Hofmann, NP1
Gitsioudis, G1
Katus, HA1
Korosoglou, G1
Bakhai, A1
Booth, J1
Delahunty, N1
Nugara, F1
Clayton, T1
McNeill, J1
Davies, SW1
Cumberland, DC1
Stables, RH1
Kandzari, DE1
Leon, MB1
Fajadet, J1
Wijns, W1
Laarman, GJ1
Kuck, KH1
Ormiston, J1
Münzel, T1
Popma, JJ2
Fitzgerald, PJ2
Bonan, R1
Kuntz, RE1
Dubé, H1
Clifford, AG1
Barry, CM1
Schwarten, DE1
Schwartz, LB3
Abizaid, A3
Lansky, AJ1
Tanajura, LF2
Feres, F2
Staico, R1
Mattos, L1
Chaves, A1
Centemero, M1
Sousa, AG1
Sousa, JE1
Zaugg, MJ1
Hattori, K1
Solberg, B1
Larracas, C1
Costa, Jde R1
Zheng, H1
Barragan, P1
Corcos, T1
Siméoni, JB1
Favereau, X1
Roquebert, PO1
Guérin, Y1
Sainsous, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Multi-Center, Non-Randomized, Single-Arm Trial to Evaluate the Safety and Feasibility of the TriMaxx Coronary Stent in de Novo Coronary Artery Lesions.[NCT00596661]Phase 1100 participants (Actual)Interventional2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phosphorylcholine and Coronary Artery Stenosis

ArticleYear
Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent.
    Journal of interventional cardiology, 2006, Volume: 19, Issue:5

    Topics: Anti-Inflammatory Agents; Blood Vessel Prosthesis Implantation; Clinical Trials as Topic; Coated Mat

2006

Trials

3 trials available for phosphorylcholine and Coronary Artery Stenosis

ArticleYear
The SV stent study: a prospective, multicentre, angiographic evaluation of the BiodivYsio phosphorylcholine coated small vessel stent in small coronary vessels.
    International journal of cardiology, 2005, Jun-22, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Coated Materials, Biocompatible; Cor

2005
Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial.
    Minerva cardioangiologica, 2007, Volume: 55, Issue:1

    Topics: Aged; Australia; Cardiovascular Agents; Coronary Angiography; Coronary Restenosis; Coronary Stenosis

2007
Percutaneous coronary revascularization using a trilayer metal phosphorylcholine-coated zotarolimus-eluting stent.
    The American journal of cardiology, 2007, May-15, Volume: 99, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis Implantation; Cardiovascular Agents; C

2007

Other Studies

4 other studies available for phosphorylcholine and Coronary Artery Stenosis

ArticleYear
Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2015, Volume: 104, Issue:1

    Topics: Aged; Autoantibodies; Biomarkers; Chi-Square Distribution; Coronary Angiography; Coronary Artery Dis

2015
Comparison of the vascular responses to balloon-expandable stenting in the coronary and peripheral circulations: long-term results in an animal model using the TriMaxx stent.
    Journal of vascular surgery, 2007, Volume: 45, Issue:4

    Topics: Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Animals; Arterial Occlusive Diseases; Coated M

2007
Clinical and angiographic results of percutaneous coronary revascularization using a trilayer stainless steel-tantalum-stainless steel phosphorylcholine-coated stent: the TriMaxx trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Dec-01, Volume: 70, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Brazil; Cardiovascular Agents; Cardiovascular Diseases; Corona

2007
Clinical experience with a new biocompatible phosphorylcholine-coated coronary stent.
    The Journal of invasive cardiology, 1999, Volume: 11, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis; Blood Vesse

1999