phosphorylcholine has been researched along with Corneal Neovascularization in 1 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Corneal Neovascularization: New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hackett, JM | 1 |
| Lagali, N | 1 |
| Merrett, K | 1 |
| Edelhauser, H | 1 |
| Sun, Y | 1 |
| Gan, L | 1 |
| Griffith, M | 1 |
| Fagerholm, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Clinical Trial to Evaluate the Safety and Effectiveness of the Collagen-phosphorylcholine Corneal Substitutes in Patients Requiring Lamellar Keratoplasty[NCT02277054] | 5 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Implant safety and tolerability will be measured by absence/presence of its lysis as well as by degree of eye inflammation based on conjunctival injection, perifocal corneal haze, aqueous humor transparency, increased intraocular pressure and self reported postoperative pain. Each item is scored 0-4: 0 = no symptom, 4 = severe symptom. (NCT02277054)
Timeframe: 12 months
| Intervention | events (Number) |
|---|---|
| RHCIII-MPC Cornea Substitute | 0 |
Cornea is considered to have healed up when there is no defect of corneal epithelium, which is confirmed by fluorescein staining of corneal surface (NCT02277054)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| RHCIII-MPC Cornea Substitute | 5 |
Improvement of 1 or more lines in Corrected Distance Visual Acuity in comparison to preoperative visual acuity (NCT02277054)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| RHCIII-MPC Cornea Substitute | 3 |
1 other study available for phosphorylcholine and Corneal Neovascularization
| Article | Year |
|---|---|
Biosynthetic corneal implants for replacement of pathologic corneal tissue: performance in a controlled rabbit alkali burn model.
Topics: Animals; Artificial Organs; Burns, Chemical; Collagen Type III; Cornea; Corneal Neovascularization; | 2011 |