phosphorylcholine has been researched along with Classical Niemann-Pick Disease in 3 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The majority of adverse events were mild and included headache, nausea, and abdominal pain." | 2.87 | Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months. ( Diaz, GA; Ji, AJ; Jouvin, MH; Lachmann, RH; Nandy, I; Puga, AC; Wasserstein, MP, 2018) |
| "Acid sphingomyelinase deficiency (ASMd, Niemann-Pick disease A/B) and Niemann-Pick type C disease (NPC) share core clinical symptoms." | 1.46 | Quantitation of plasmatic lysosphingomyelin and lysosphingomyelin-509 for differential screening of Niemann-Pick A/B and C diseases. ( Asfaw, B; Gulinello, ME; Jahnova, H; Kuchar, L; Ledvinova, J; Lugowska, A; Malinova, V; Poupetova, H; Sikora, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wasserstein, MP | 1 |
| Diaz, GA | 1 |
| Lachmann, RH | 1 |
| Jouvin, MH | 1 |
| Nandy, I | 1 |
| Ji, AJ | 1 |
| Puga, AC | 1 |
| Kuchar, L | 1 |
| Sikora, J | 1 |
| Gulinello, ME | 1 |
| Poupetova, H | 1 |
| Lugowska, A | 1 |
| Malinova, V | 1 |
| Jahnova, H | 1 |
| Asfaw, B | 1 |
| Ledvinova, J | 1 |
| Chiulli, N | 1 |
| Codazzi, F | 1 |
| Di Cesare, A | 1 |
| Gravaghi, C | 1 |
| Zacchetti, D | 1 |
| Grohovaz, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Long-Term Study to Assess the Ongoing Safety and Efficacy of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency[NCT02004704] | Phase 2 | 25 participants (Actual) | Interventional | 2013-12-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for phosphorylcholine and Classical Niemann-Pick Disease
| Article | Year |
|---|---|
Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months.
Topics: Adult; Biomarkers; Bone Density; Enzyme Replacement Therapy; Female; Hexosaminidases; Humans; Lipids | 2018 |
2 other studies available for phosphorylcholine and Classical Niemann-Pick Disease
| Article | Year |
|---|---|
Quantitation of plasmatic lysosphingomyelin and lysosphingomyelin-509 for differential screening of Niemann-Pick A/B and C diseases.
Topics: Biomarkers; Case-Control Studies; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Niemann- | 2017 |
Sphingosylphosphocholine effects on cultured astrocytes reveal mechanisms potentially involved in neurotoxicity in Niemann-Pick type A disease.
Topics: Animals; Apoptosis; Astrocytes; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Fluorescent Dy | 2007 |