Page last updated: 2024-10-19

phosphorylcholine and Chronic Illness

phosphorylcholine has been researched along with Chronic Illness in 20 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"After 4 weeks of treatment, Urticaria Activity Score (UAS7) levels were substantially more reduced in miltefosine-treated patients (-6."9.17Randomized, double-blind, placebo-controlled study of safety and efficacy of miltefosine in antihistamine-resistant chronic spontaneous urticaria. ( Bieber, T; Biedermann, T; Brasch, J; Dominicus, R; Hunzelmann, N; Jakob, T; Magerl, M; Mahler, V; Maurer, M; Popp, G; Rother, M; Schäkel, K; Schlingensiepen, R; Schmitt, J; Siebenhaar, F; Simon, JC; Staubach, P; Wedi, B; Weidner, C, 2013)
"A prospective randomized double-blind controlled trial in children with recurrent acute otitis media and chronic otitis media with effusion; 240 children were randomized to receive a phosphorylcholine-coated tube in one ear and an uncoated tube in the other."9.15A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media. ( Corsten, G; Hong, P; Johnson, LB; Smith, N, 2011)
"After 4 weeks of treatment, Urticaria Activity Score (UAS7) levels were substantially more reduced in miltefosine-treated patients (-6."5.17Randomized, double-blind, placebo-controlled study of safety and efficacy of miltefosine in antihistamine-resistant chronic spontaneous urticaria. ( Bieber, T; Biedermann, T; Brasch, J; Dominicus, R; Hunzelmann, N; Jakob, T; Magerl, M; Mahler, V; Maurer, M; Popp, G; Rother, M; Schäkel, K; Schlingensiepen, R; Schmitt, J; Siebenhaar, F; Simon, JC; Staubach, P; Wedi, B; Weidner, C, 2013)
"A prospective randomized double-blind controlled trial in children with recurrent acute otitis media and chronic otitis media with effusion; 240 children were randomized to receive a phosphorylcholine-coated tube in one ear and an uncoated tube in the other."5.15A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media. ( Corsten, G; Hong, P; Johnson, LB; Smith, N, 2011)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's9 (45.00)18.2507
2000's2 (10.00)29.6817
2010's5 (25.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Dean, DA1
Gautham, G1
Siqueira-Neto, JL1
McKerrow, JH1
Dorrestein, PC1
McCall, LI1
Mano, C1
Kongkaew, A1
Tippawangkosol, P1
Junkum, A1
Siriyasatien, P1
Jariyapan, N1
Zhao, C1
Li, Z1
Ji, L1
Ma, J1
Ge, RL1
Cui, S1
Barrio, S1
Gallardo, M1
Arenas, A1
Ayala, R1
Rapado, I1
Rueda, D1
Jiménez-Ubieto, A1
Albizua, E1
Burgaleta, C1
Gilsanz, F1
Martinez-Lopez, J1
Hong, P1
Smith, N1
Johnson, LB1
Corsten, G1
Magerl, M1
Rother, M1
Bieber, T1
Biedermann, T1
Brasch, J1
Dominicus, R1
Hunzelmann, N1
Jakob, T1
Mahler, V1
Popp, G1
Schäkel, K1
Schlingensiepen, R1
Schmitt, J1
Siebenhaar, F1
Simon, JC1
Staubach, P1
Wedi, B1
Weidner, C1
Maurer, M1
Bahadue, FL1
Soll, R1
Vasseneix, C1
Gargala, G1
François, A1
Hellot, MF1
Duclos, C1
Muraine, M1
Benichou, J1
Ballet, JJ1
Brasseur, G1
Favennec, L1
Barbier, M1
Oliver, A1
Rao, J1
Hanna, SL1
Goldberg, JB1
Albertí, S1
Proietti, C1
Imperiale, A1
Chiti, D1
Sell, M1
Cotton, R1
Hirata, T1
Guthrie, R1
LeBlanc, M1
Mammel, M1
Long, W2
Sauve, R1
Vincer, M1
Bard, H1
Derleth, D1
Stevenson, D1
Pauly, T1
Robertson, C1
Anzueto, A1
Jubran, A1
Ohar, JA1
Piquette, CA1
Rennard, SI1
Colice, G1
Pattishall, EN1
Barrett, J1
Engle, M1
Perret, KA1
Rubin, BK1
Aramaki, M1
Nagasawa, T1
Koseki, T1
Ishikawa, I1
Potwarka, JJ1
Drost, DJ1
Williamson, PC1
Carr, T1
Canaran, G1
Rylett, WJ1
Neufeld, RW1
Salvadorini, F1
Galeone, F1
Marescotti, V1
Saba, P1
Lal, RB1
Dhawan, RR1
Ramzy, RM1
Farris, RM1
Gad, AA1
Nightingale, SL1
Nishinarita, S1
Sawada, S1
Horie, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pulse Oximetry With Clinical Observation to Screen for Lung Disease in Neonates[NCT02533583]15,000 participants (Anticipated)Observational2015-11-30Active, not recruiting
Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants: an International Multicentric Randomized Control Trial (LUNG Study)[NCT05198375]668 participants (Anticipated)Interventional2022-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phosphorylcholine and Chronic Illness

ArticleYear
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant

2012

Trials

7 trials available for phosphorylcholine and Chronic Illness

ArticleYear
A randomized double-blind controlled trial of phosphorylcholine-coated tympanostomy tube versus standard tympanostomy tube in children with recurrent acute and chronic otitis media.
    The Laryngoscope, 2011, Volume: 121, Issue:1

    Topics: Acute Disease; Child; Child, Preschool; Chronic Disease; Coated Materials, Biocompatible; Double-Bli

2011
Randomized, double-blind, placebo-controlled study of safety and efficacy of miltefosine in antihistamine-resistant chronic spontaneous urticaria.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27, Issue:3

    Topics: Chronic Disease; Double-Blind Method; Histamine Antagonists; Humans; Phosphorylcholine; Placebos; Ur

2013
One-year follow-up of 273 infants with birth weights of 700 to 1100 grams after prophylactic treatment of respiratory distress syndrome with synthetic surfactant or air placebo. American Exosurf Neonatal Study Group I.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Fem

1995
Outcome at 1-year adjusted age of 957 infants weighing more than 1250 grams with respiratory distress syndrome randomized to receive synthetic surfactant or air placebo. American and Canadian Exosurf Neonatal Study Groups.
    The Journal of pediatrics, 1995, Volume: 126, Issue:5 Pt 2

    Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Fem

1995
A multicenter, randomized trial comparing synthetic surfactant with modified bovine surfactant extract in the treatment of neonatal respiratory distress syndrome. Vermont-Oxford Neonatal Network.
    Pediatrics, 1996, Volume: 97, Issue:1

    Topics: Biological Products; Chronic Disease; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Low

1996
Effects of aerosolized surfactant in patients with stable chronic bronchitis: a prospective randomized controlled trial.
    JAMA, 1997, Nov-05, Volume: 278, Issue:17

    Topics: Administration, Intranasal; Aerosols; Aged; Bronchitis; Chronic Disease; Double-Blind Method; Drug C

1997
A 1H-decoupled 31P chemical shift imaging study of medicated schizophrenic patients and healthy controls.
    Biological psychiatry, 1999, Mar-15, Volume: 45, Issue:6

    Topics: Adult; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Chronic Disease; Female; Humans; Magne

1999

Other Studies

12 other studies available for phosphorylcholine and Chronic Illness

ArticleYear
Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:10

    Topics: Animals; Carnitine; Chagas Cardiomyopathy; Chronic Disease; Heart; Humans; Male; Metabolomics; Mice;

2021
In vitro susceptibility to miltefosine of amphotericin B-resistant Leishmania (Mundinia) martiniquensis.
    Parasitology research, 2023, Volume: 122, Issue:12

    Topics: Amphotericin B; Antiprotozoal Agents; Chronic Disease; Humans; Leishmania; Leishmaniasis; Leishmania

2023
PI3K-Akt Signal Transduction Molecules Maybe Involved in Downregulation of Erythroblasts Apoptosis and Perifosine Increased Its Apoptosis in Chronic Mountain Sickness.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Nov-26, Volume: 23

    Topics: Adult; Altitude Sickness; Apoptosis; bcl-X Protein; Bone Marrow Cells; Caspase 9; Celecoxib; China;

2017
Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm.
    British journal of haematology, 2013, Volume: 161, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Cell Proliferation; Cells, Cultured; Chronic D

2013
A keratitis rat model for evaluation of anti-Acanthamoeba polyphaga agents.
    Cornea, 2006, Volume: 25, Issue:5

    Topics: Acanthamoeba; Acanthamoeba Keratitis; Administration, Topical; Animals; Antiprotozoal Agents; Benzam

2006
Novel phosphorylcholine-containing protein of Pseudomonas aeruginosa chronic infection isolates interacts with airway epithelial cells.
    The Journal of infectious diseases, 2008, Feb-01, Volume: 197, Issue:3

    Topics: Acute Disease; Animals; Bacterial Proteins; Chronic Disease; Disease Models, Animal; Humans; Mice; M

2008
[Treatment of chronic hepatopathies with phosphorylcholine and pantethine].
    La Clinica terapeutica, 1984, Aug-15, Volume: 110, Issue:3

    Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Female; Humans; Liver Diseases; Male; Midd

1984
Presence of activated B-1 cells in chronic inflamed gingival tissue.
    Journal of clinical immunology, 1998, Volume: 18, Issue:6

    Topics: Adult; Antibodies, Bacterial; B-Lymphocyte Subsets; Chronic Disease; DNA, Single-Stranded; Escherich

1998
[Effect of CDP-choline on GH release in patients with chronic psychopathy].
    La Clinica terapeutica, 1978, Jun-30, Volume: 85, Issue:6

    Topics: Adult; Choline; Chronic Disease; Depression; Female; Growth Hormone; Humans; Male; Mental Disorders;

1978
C-reactive protein in patients with lymphatic filariasis: increased expression on lymphocytes in chronic lymphatic obstruction.
    Journal of clinical immunology, 1991, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antigens, Helminth; Binding, Competitive; C-Reactive Protein; Chro

1991
From the Food and Drug Administration.
    JAMA, 1990, Oct-10, Volume: 264, Issue:14

    Topics: Chronic Disease; Diet Fads; Dietary Fiber; Drug Combinations; Esophageal Stenosis; Fatty Alcohols; F

1990
Phosphorylcholine antibodies in pulmonary infection.
    Medical microbiology and immunology, 1990, Volume: 179, Issue:4

    Topics: Acute Disease; Adult; Aged; Animals; Antibody Specificity; B-Lymphocytes; Bronchitis; Bronchopneumon

1990