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phosphorylcholine and Cancer of Colon

phosphorylcholine has been researched along with Cancer of Colon in 11 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
" Human HT29 (colon) and MDA-MB-231 (breast) carcinoma cells were examined by proton (1H) and phosphorus (31P) magnetic resonance spectroscopy (MRS) before and after treatment with MN58b both in culture and in xenografts."3.73Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models. ( Al-Saffar, NM; Chung, YL; Griffiths, JR; Jackson, LE; Judson, IR; Lacal, JC; Leach, MO; Madhu, B; Ramírez de Molina, A; Troy, H; Workman, P, 2006)
"Treatment with LAQ824 resulted in altered phospholipid metabolism and compromised tumor bioenergetics."1.35Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. ( Aherne, W; Atadja, P; Beloueche-Babari, M; Chung, YL; Griffiths, JR; Jackson, LE; Judson, IR; Kristeleit, R; Leach, MO; Troy, H; Workman, P, 2008)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Adamová, B2
Říhová, K2
Pokludová, J2
Beneš, P2
Šmarda, J2
Navrátilová, J2
Morii, Y1
Tsubaki, M1
Takeda, T1
Otubo, R1
Seki, S1
Yamatomo, Y1
Imano, M1
Satou, T1
Shimomura, K1
Nishida, S1
Yamada, H1
Hasegawa, Y1
Imai, H1
Takayama, Y1
Sugihara, F1
Matsuda, T1
Tochio, H1
Shirakawa, M1
Sando, S1
Kimura, Y1
Toshimitsu, A1
Aoyama, Y1
Kondo, T1
Chen, YC1
Tsai, TL1
Ye, XH1
Lin, TH1
Teymouri, M1
Farzaneh, H1
Badiee, A1
Golmohammadzadeh, S1
Sadri, K1
Jaafari, MR1
Gao, D1
Wang, Y1
Xie, W1
Yang, T1
Jiang, Y1
Guo, Y1
Guan, J1
Liu, H1
Beloueche-Babari, M2
Arunan, V1
Troy, H3
te Poele, RH1
te Fong, AC1
Jackson, LE3
Payne, GS1
Griffiths, JR3
Judson, IR3
Workman, P3
Leach, MO3
Chung, YL3
Mori, N1
Delsite, R1
Natarajan, K1
Kulawiec, M1
Bhujwalla, ZM1
Singh, KK1
Al-Saffar, NM1
Ramírez de Molina, A1
Madhu, B1
Lacal, JC1
Kristeleit, R1
Aherne, W1
Atadja, P1
Nakagami, K1
Uchida, T1
Ohwada, S1
Koibuchi, Y1
Suda, Y1
Sekine, T1
Morishita, Y1

Other Studies

11 other studies available for phosphorylcholine and Cancer of Colon

ArticleYear
Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Humans; Phosp

2023
Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Humans; Phosp

2023
Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Humans; Phosp

2023
Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Humans; Phosp

2023
Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in colon cancer cells harboring the PIK3CA mutation.
    European journal of pharmacology, 2021, May-05, Volume: 898

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caco-2 Cel

2021
Magnetic resonance imaging of tumor with a self-traceable phosphorylcholine polymer.
    Journal of the American Chemical Society, 2015, Jan-21, Volume: 137, Issue:2

    Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Magnetic Resonance Imaging; Mice; Phosphorylcholine; P

2015
Anti-proliferative effect on a colon adenocarcinoma cell line exerted by a membrane disrupting antimicrobial peptide KL15.
    Cancer biology & therapy, 2015, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Amino Acid Sequence; Antimicrobial Cationic Peptides; Bacterial Proteins; Caco-2 Cel

2015
Investigation of Hexadecylphosphocholine (miltefosine) usage in Pegylated liposomal doxorubicin as a synergistic ingredient: In vitro and in vivo evaluation in mice bearing C26 colon carcinoma and B16F0 melanoma.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Dec-01, Volume: 80

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Delivery Syst

2015
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Mar-01, Volume: 1014

    Topics: Antineoplastic Agents; Biological Products; Cell Survival; Chromatography, High Pressure Liquid; Col

2016
Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.
    Cancer research, 2012, Feb-15, Volume: 72, Issue:4

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Choline Kinase; Colonic Neoplasms; Drug Evaluation, Pr

2012
Loss of p53 function in colon cancer cells results in increased phosphocholine and total choline.
    Molecular imaging, 2004, Volume: 3, Issue:4

    Topics: Cell Line, Tumor; Choline; Colonic Neoplasms; Gene Deletion; Genes, p53; Humans; Mutation; Phosphory

2004
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
    Cancer research, 2006, Jan-01, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Butanes; Carcinoma; Choline Kin

2006
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:4

    Topics: Acetylation; Animals; Biomarkers, Tumor; Blotting, Western; Cell Cycle; Cell Proliferation; Colonic

2008
Increased choline kinase activity and elevated phosphocholine levels in human colon cancer.
    Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Blotting, Western; Case-Control Studies; Choline Kinase; Colonic Neo

1999